Searching for up to 100 curated homologs for GFF2461 FitnessBrowser__Marino:GFF2461 (258 a.a.)
Found high-coverage hits (≥70%) to 64 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Amt / b4214 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
cysQ / P22255 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) from Escherichia coli (strain K12) (see 7 papers)
CYSQ_ECOLI / P22255 3'(2'),5'-bisphosphate nucleotidase CysQ; 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase; EC 3.1.3.7 from Escherichia coli (strain K12) (see 5 papers)
45% identity, 95% coverage of query (202 bits)
pssB / AAA81571.1 pssB from Rhizobium leguminosarum (see paper)
43% identity, 96% coverage of query (168 bits)
5zonA / P95189 Histidinol phosphate phosphatase from mycobacterium tuberculosis (see paper)
32% identity, 90% coverage of query (85.9 bits)
5yhtA Crystal structure of a phosphatase from mycobacterium tuberculosis in complex with its substrate
32% identity, 90% coverage of query (85.9 bits)
HISN_MYCTU / P95189 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P95189 histidinol-phosphatase (EC 3.1.3.15) from Mycobacterium tuberculosis (see paper)
32% identity, 90% coverage of query (85.5 bits)
hisN / Q8NS80 histidinol-phosphatase (EC 3.1.3.15) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 2 papers)
HISN_CORGL / Q8NS80 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
Q8NS80 histidinol-phosphatase (EC 3.1.3.15) from Corynebacterium glutamicum (see 2 papers)
30% identity, 80% coverage of query (83.6 bits)
Build an alignment for GFF2461 and 6 homologs with ≥ 30% identity
Or download the sequences
TM1415 / O33832 inositol monophosphatase subunit (EC 3.1.3.25) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
BSUHB_THEMA / O33832 Fructose-1,6-bisphosphatase/inositol-1-monophosphatase; FBPase/IMPase; Inositol-1-phosphatase; I-1-Pase; EC 3.1.3.11; EC 3.1.3.25 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 3 papers)
O33832 inositol-phosphate phosphatase (EC 3.1.3.25) from Thermotoga maritima (see paper)
2p3nA / O33832 Thermotoga maritima impase tm1415 (see paper)
28% identity, 79% coverage of query (81.3 bits)
Ga0059261_2035 Histidinol-phosphatase [alternative form] (EC 3.1.3.15) from Sphingomonas koreensis DSMZ 15582
28% identity, 89% coverage of query (78.6 bits)
Q5U789 L-galactose 1-phosphate phosphatase (EC 3.1.3.93) from Actinidia deliciosa (see paper)
26% identity, 93% coverage of query (76.6 bits)
IMP2_SOLLC / P54927 Inositol monophosphatase 2; IMP 2; IMPase 2; LeIMP2; Inositol-1(or 4)-monophosphatase 2; EC 3.1.3.25 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see 2 papers)
26% identity, 84% coverage of query (73.9 bits)
HISN_STRCO / Q9K4B1 Histidinol-phosphatase; HolPase; Histidinol-phosphate phosphatase; EC 3.1.3.15 from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
31% identity, 80% coverage of query (72.0 bits)
Q3LS17 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) from Arthrospira platensis (see paper)
29% identity, 86% coverage of query (72.0 bits)
VTC4 / Q9M8S8 L-galactose-1-phosphate phosphatase//inositol or phosphatidylinositol phosphatase (EC 3.1.3.25; EC 3.1.3.93) from Arabidopsis thaliana (see 3 papers)
VTC4_ARATH / Q9M8S8 Inositol-phosphate phosphatase; L-galactose 1-phosphate phosphatase; Myo-inositol monophosphatase; EC 3.1.3.25; EC 3.1.3.93 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9M8S8 inositol-phosphate phosphatase (EC 3.1.3.25); L-galactose 1-phosphate phosphatase (EC 3.1.3.93) from Arabidopsis thaliana (see 5 papers)
26% identity, 82% coverage of query (71.6 bits)
B3DFH0 inositol-phosphate phosphatase (EC 3.1.3.25) from Hordeum vulgare (see paper)
27% identity, 88% coverage of query (71.2 bits)
AZOBR_RS03845 Histidinol-phosphatase [alternative form] (EC 3.1.3.15) from Azospirillum brasilense Sp245
27% identity, 87% coverage of query (70.9 bits)
IMP1_SOLLC / P54926 Inositol monophosphatase 1; IMP 1; IMPase 1; LeIMP1; Inositol-1(or 4)-monophosphatase 1; EC 3.1.3.25 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
26% identity, 96% coverage of query (70.1 bits)
Q23493 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) from Caenorhabditis elegans (see paper)
26% identity, 97% coverage of query (70.1 bits)
B3GK03 L-galactose 1-phosphate phosphatase (EC 3.1.3.93) from Nicotiana tabacum (see paper)
26% identity, 93% coverage of query (68.9 bits)
IMP3_SOLLC / P54928 Inositol monophosphatase 3; IMP 3; IMPase 3; LeIMP3; Inositol-1(or 4)-monophosphatase 3; EC 3.1.3.25 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see paper)
26% identity, 88% coverage of query (68.6 bits)
IMPA3_MOUSE / Q80V26 Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase; Golgi-resident PAP phosphatase; gPAPP; 3'(2'), 5'-bisphosphate nucleotidase 2; Inositol monophosphatase domain-containing protein 1; Myo-inositol monophosphatase A3; Phosphoadenosine phosphate 3'-nucleotidase; EC 3.1.3.7 from Mus musculus (Mouse) (see paper)
25% identity, 74% coverage of query (67.0 bits)
PGA1_c21860 Histidinol-phosphatase [alternative form] (EC 3.1.3.15) from Phaeobacter inhibens BS107
30% identity, 88% coverage of query (65.9 bits)
A0A1I9GET0 inositol-phosphate phosphatase (EC 3.1.3.25) from Staphylococcus aureus (see 2 papers)
25% identity, 85% coverage of query (65.1 bits)
6ib8B / P0ADG4 Structure of a complex of suhb and nusa ar2 domain (see paper)
26% identity, 90% coverage of query (64.7 bits)
SUHB_PSEAE / Q9HXI4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
28% identity, 88% coverage of query (64.7 bits)
SsyA / b2533 Nus factor SuhB (EC 3.1.3.25; EC 3.1.3.19) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
suhB / P0ADG4 Nus factor SuhB (EC 3.1.3.25; EC 3.1.3.19) from Escherichia coli (strain K12) (see 16 papers)
SUHB_ECOLI / P0ADG4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Escherichia coli (strain K12) (see 14 papers)
26% identity, 88% coverage of query (64.7 bits)
5dw8A Crystal structure of 2'amp bound saimpase-ii
27% identity, 76% coverage of query (63.9 bits)
2qflA Structure of suhb: inositol monophosphatase and extragenic suppressor from e. Coli
26% identity, 88% coverage of query (63.9 bits)
6tqoT Rrn anti-termination complex
26% identity, 86% coverage of query (63.5 bits)
INPP_ENTH1 / C4M633 Inositol polyphosphate 1-phosphatase; EhIPPase; 3'(2'),5'-bisphosphate nucleotidase; EC 3.1.3.57; EC 3.1.3.7 from Entamoeba histolytica (strain ATCC 30459 / HM-1:IMSS / ABRM) (see paper)
25% identity, 92% coverage of query (63.2 bits)
4qxdB / C4M633 Crystal structure of inositol polyphosphate 1-phosphatase from entamoeba histolytica (see paper)
25% identity, 92% coverage of query (63.2 bits)
5j16A Crystal structure of inositol monophosphate bound saimpase-ii
27% identity, 76% coverage of query (63.2 bits)
INM2_YEAST / Q05533 Inositol monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2; EC 3.1.3.25 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
27% identity, 72% coverage of query (62.8 bits)
SUHB_SALT1 / A0A0F6B4W4 Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Salmonella typhimurium (strain 14028s / SGSC 2262) (see paper)
26% identity, 88% coverage of query (62.8 bits)
3lv0A / A0A0H3M6W8 Crystal structure of extragenic suppressor protein suhb from bartonella henselae, native
28% identity, 93% coverage of query (61.6 bits)
SUHB_BURCJ / B4ED80 Putative Nus factor SuhB; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.25 from Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) (see paper)
27% identity, 75% coverage of query (59.3 bits)
CYSQ_MYCTU / P9WKJ1 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; 3'(2'),5'-bisphosphate nucleotidase; 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; D-fructose-1,6-bisphosphate 1-phosphohydrolase; DPNPase; Fructose-1,6-bisphosphatase; FBPase; Inositol-1-monophosphatase; I-1-Pase; IMPase; Inositol-1-phosphatase; EC 3.1.3.7; EC 3.1.3.11; EC 3.1.3.25 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WKJ1 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) from Mycobacterium tuberculosis (see 2 papers)
30% identity, 80% coverage of query (59.3 bits)
5djjA / P9WKJ1 Structure of m. Tuberculosis cysq, a pap phosphatase with po4 and 2mg bound (see paper)
29% identity, 80% coverage of query (58.9 bits)
IMPA2 / O14732 inositol monophosphatase 2 monomer (EC 3.1.3.25) from Homo sapiens (see 5 papers)
IMPA2_HUMAN / O14732 Inositol monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2; EC 3.1.3.25 from Homo sapiens (Human) (see 3 papers)
26% identity, 87% coverage of query (58.5 bits)
5djkA Structure of m. Tuberculosis cysq, a pap phosphatase with po4 and 2ca bound
29% identity, 80% coverage of query (58.5 bits)
5djhA Structure of m. Tuberculosis cysq, a pap phosphatase with amp, po4, and 3mg bound
27% identity, 80% coverage of query (58.5 bits)
5djgA Structure of m. Tuberculosis cysq, a pap phosphatase with pap, mg, and li bound
27% identity, 80% coverage of query (58.2 bits)
3luzA Crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacement
28% identity, 93% coverage of query (57.4 bits)
IMPA2_MOUSE / Q91UZ5 Inositol monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-monophosphatase 2; Myo-inositol monophosphatase A2; EC 3.1.3.25 from Mus musculus (Mouse) (see paper)
Q91UZ5 inositol-phosphate phosphatase (EC 3.1.3.25) from Mus musculus (see paper)
25% identity, 94% coverage of query (57.0 bits)
1k9yA / P32179 The papase hal2p complexed with magnesium ions and reaction products: amp and inorganic phosphate (see paper)
23% identity, 85% coverage of query (57.0 bits)
MET22_YEAST / P32179 3'(2'),5'-bisphosphate nucleotidase; 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; DPNPase; Halotolerance protein HAL2; Methionine-requiring protein 22; EC 3.1.3.7 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
23% identity, 85% coverage of query (57.0 bits)
1qgxA X-ray structure of yeast hal2p
23% identity, 85% coverage of query (57.0 bits)
1ka1A The papase hal2p complexed with calcium and magnesium ions and reaction substrate: pap
23% identity, 85% coverage of query (57.0 bits)
1k9zA The papase hal2p complexed with zinc ions
23% identity, 85% coverage of query (57.0 bits)
IMPL1_ARATH / Q94F00 Phosphatase IMPL1, chloroplastic; Protein MYO-INOSITOL MONOPHOSPHATASE-LIKE 1; EC 3.1.3.25 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q94F00 inositol-phosphate phosphatase (EC 3.1.3.25) from Arabidopsis thaliana (see 3 papers)
24% identity, 92% coverage of query (56.6 bits)
IMPA1_CAEEL / Q19420 Inositol monophosphatase ttx-7; IMP; IMPase; Abnormal thermotaxis protein 7; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase; EC 3.1.3.25; EC 3.1.3.94 from Caenorhabditis elegans (see 2 papers)
23% identity, 79% coverage of query (55.1 bits)
3luzB / A0A0H3M6W8 Crystal structure of extragenic suppressor protein suhb from bartonella henselae, via combined iodide sad molecular replacement (see paper)
31% identity, 79% coverage of query (55.1 bits)
4as5A / O55023 Structure of mouse inositol monophosphatase 1 (see paper)
22% identity, 94% coverage of query (53.1 bits)
IMPA1_MOUSE / O55023 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Mus musculus (Mouse) (see 3 papers)
O55023 inositol-phosphate phosphatase (EC 3.1.3.25) from Mus musculus (see 2 papers)
22% identity, 94% coverage of query (52.8 bits)
2bjiA / P20456 High resolution structure of myo-inositol monophosphatase, the target of lithium therapy (see paper)
22% identity, 90% coverage of query (51.2 bits)
IMPA1_BOVIN / P20456 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Bos taurus (Bovine) (see 2 papers)
22% identity, 90% coverage of query (51.2 bits)
1imdA Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis
21% identity, 90% coverage of query (48.9 bits)
6giuA / P29218 Human impase with l-690330 (see paper)
21% identity, 90% coverage of query (48.5 bits)
IMPA1 / P29218 inositol monophosphatase 1 monomer (EC 3.1.3.25) from Homo sapiens (see 5 papers)
IMPA1_HUMAN / P29218 Inositol monophosphatase 1; IMP 1; IMPase 1; D-galactose 1-phosphate phosphatase; Inositol-1(or 4)-monophosphatase 1; Lithium-sensitive myo-inositol monophosphatase A1; EC 3.1.3.25; EC 3.1.3.94 from Homo sapiens (Human) (see 9 papers)
P29218 inositol-phosphate phosphatase (EC 3.1.3.25) from Homo sapiens (see 4 papers)
21% identity, 90% coverage of query (48.5 bits)
6zk0AAA human impase with ebselen
21% identity, 90% coverage of query (48.5 bits)
4as4A Structure of human inositol monophosphatase 1
21% identity, 90% coverage of query (48.5 bits)
2hhmA Structure of inositol monophosphatase, the putative target of lithium therapy
21% identity, 90% coverage of query (48.5 bits)
1imbA Structural analysis of inositol monophosphatase complexes with substrates
21% identity, 90% coverage of query (48.5 bits)
1awbA Human myo-inositol monophosphatase in complex with d-inositol-1- phosphate and calcium
21% identity, 90% coverage of query (48.5 bits)
Q8NS79 histidinol-phosphatase (EC 3.1.3.15) from Corynebacterium glutamicum (see paper)
25% identity, 77% coverage of query (46.2 bits)
Or start over
Lawrence Berkeley National Laboratory