Searching for up to 100 curated homologs for GFF2489 FitnessBrowser__WCS417:GFF2489 (493 a.a.)

Found high-coverage hits (≥70%) to 16 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

1lj8A / O08355 Crystal structure of mannitol dehydrogenase in complex with NAD (see paper)
    95% identity, 100% coverage of query (951 bits)

O08355 mannitol 2-dehydrogenase (EC 1.1.1.67) from Pseudomonas fluorescens (see 5 papers)
    95% identity, 100% coverage of query (951 bits)

1m2wA Pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with NAD and d-mannitol
    95% identity, 100% coverage of query (951 bits)

M2DH_ASPFU / Q4WQY4 Mannitol 2-dehydrogenase; M2DH; MDH; EC 1.1.1.67 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
Q4WQY4 mannitol 2-dehydrogenase (EC 1.1.1.67) from Aspergillus fumigatus (see 2 papers)
    44% identity, 98% coverage of query (413 bits)

7rk5B / Q4WQY4 Mannitol-2-dehydrogenase bound to nadh from aspergillus fumigatus
    44% identity, 98% coverage of query (411 bits)

DSF1_YEAST / P0CX08 Mannitol dehydrogenase DSF1; Deletion suppressor of MPT5 mutation protein 1; EC 1.1.1.67 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
MAN2_YEAST / P0CX09 Mannitol dehydrogenase 2; EC 1.1.1.67 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    42% identity, 99% coverage of query (401 bits)

Q9KWR5 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Gluconobacter oxydans (see paper)
    43% identity, 87% coverage of query (363 bits)

sr / BAB83933.1 L-sorbose reductase from Gluconobacter oxydans (see paper)
    43% identity, 87% coverage of query (360 bits)

YeiQ / b2172 putative oxidoreductase YeiQ from Escherichia coli K-12 substr. MG1655 (see 2 papers)
    40% identity, 97% coverage of query (351 bits)

R9UHL6 mannitol 2-dehydrogenase (EC 1.1.1.67) from Saccharina japonica (see paper)
    40% identity, 94% coverage of query (347 bits)

UxuB / b4323 D-mannonate oxidoreductase (EC 1.1.1.57) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
uxuB / P39160 D-mannonate oxidoreductase (EC 1.1.1.57) from Escherichia coli (strain K12) (see 4 papers)
    40% identity, 95% coverage of query (341 bits)

4im7A / A0A0H2V7F2 Crystal structure of fructuronate reductase (ydfi) from e. Coli cft073 (efi target efi-506389) complexed with nadh and d-mannonate
    39% identity, 96% coverage of query (333 bits)

YdfI / b1542 putative oxidoreductase YdfI from Escherichia coli K-12 substr. MG1655 (see 2 papers)
    39% identity, 96% coverage of query (333 bits)

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Build an alignment for GFF2489 and 13 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

uxuB / Q9WXS3 D-mannonate dehydrogenase (EC 1.1.1.57) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
UXUB_THEMA / Q9WXS3 D-mannonate oxidoreductase; Fructuronate reductase; Mannonate dehydrogenase; EC 1.1.1.57 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
    29% identity, 70% coverage of query (127 bits)

CA265_RS19880 Altronate oxidoreductase (EC 1.1.1.58) from Pedobacter sp. GW460-11-11-14-LB5
    24% identity, 99% coverage of query (120 bits)

UxaB / b1521 tagaturonate reductase (EC 1.1.1.58) from Escherichia coli K-12 substr. MG1655 (see 11 papers)
uxaB / P0A6L7 tagaturonate reductase (EC 1.1.1.58) from Escherichia coli (strain K12) (see 10 papers)
    24% identity, 82% coverage of query (95.9 bits)

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