Searching for up to 100 curated homologs for GFF260 FitnessBrowser__WCS417:GFF260 (291 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
O54574 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptococcus pneumoniae (see paper)
70% identity, 99% coverage of query (425 bits)
cps19fL / AAC44969.1 glucose-1-phosphate thymidyl transferase from Streptococcus pneumoniae (see 2 papers)
69% identity, 99% coverage of query (422 bits)
4ho9A / Q9AGY4 Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with udp-galactose and utp
70% identity, 98% coverage of query (419 bits)
rmlA / Q6T1W3 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Aneurinibacillus thermoaerophilus (see 3 papers)
70% identity, 98% coverage of query (419 bits)
4ho4A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with thymidine and glucose-1-phosphate
70% identity, 98% coverage of query (419 bits)
4ho6A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with udp-glucose and utp
70% identity, 98% coverage of query (419 bits)
4ho5A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with tdp-glucose
70% identity, 98% coverage of query (419 bits)
4ho3A Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with thymidine triphosphate
70% identity, 98% coverage of query (419 bits)
RMLA_STRMU / P95778 Glucose-1-phosphate thymidylyltransferase; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase; EC 2.7.7.24 from Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (see paper)
69% identity, 99% coverage of query (414 bits)
rmlA / Q6E7F3 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Escherichia coli (see paper)
69% identity, 98% coverage of query (414 bits)
4hocA Crystal structure of glucose 1-phosphate thymidylyltransferase from aneurinibacillus thermoaerophilus complexed with udp-n- acetylglucosamine
70% identity, 98% coverage of query (412 bits)
YifG / b3789 dTDP-glucose pyrophosphorylase 2 (EC 2.7.7.24) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
rffH / P61887 glucose-1-phosphate thymidylyltransferase 2 (EC 2.7.7.24) from Escherichia coli (strain K12) (see 4 papers)
RMLA2_ECOLI / P61887 Glucose-1-phosphate thymidylyltransferase 2; G1P-TT 2; dTDP-glucose pyrophosphorylase 2; dTDP-glucose synthase 2; EC 2.7.7.24 from Escherichia coli (strain K12) (see 2 papers)
rmlA2 / RF|NP_418236 dTDP-glucose pyrophosphorylase 2; EC 2.7.7.24 from Escherichia coli K12 (see 6 papers)
67% identity, 98% coverage of query (406 bits)
1mc3A / P61887 Crystal structure of rffh (see paper)
67% identity, 98% coverage of query (406 bits)
1lvwA / O27819 Crystal structure of glucose-1-phosphate thymidylyltransferase, rmla, complex with dtdp
67% identity, 99% coverage of query (405 bits)
rfbC/D / AAA63158.1 TDP-deoxyglucose-epimerase from Neisseria meningitidis (see paper)
66% identity, 99% coverage of query (401 bits)
Q9HU22 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Pseudomonas aeruginosa (see paper)
65% identity, 99% coverage of query (395 bits)
4b5bA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (395 bits)
4b4gA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (395 bits)
4b42A Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (395 bits)
4b3uA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (395 bits)
4asyA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (395 bits)
4b2xB / Q9HU22 Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
65% identity, 99% coverage of query (394 bits)
4b4mA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
4asjA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
1g3lA The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (rmla). Tdp-l-rhamnose complex.
65% identity, 99% coverage of query (394 bits)
1g2vA The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (rmla). Ttp complex.
65% identity, 99% coverage of query (394 bits)
1g1lA The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (rmla). Tdp-glucose complex.
65% identity, 99% coverage of query (394 bits)
1g0rA The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (rmla). Thymidine/glucose- 1-phosphate complex.
65% identity, 99% coverage of query (394 bits)
1fxoA The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (rmla). Tmp complex.
65% identity, 99% coverage of query (394 bits)
5fu8A Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
4b2wA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
5fuhA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
4b4bA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
5fyeA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
5fu0A Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
5ftvA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
5ftsA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
4arwA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
3zllA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
3zlkA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
65% identity, 99% coverage of query (394 bits)
6n0uA / B2JFC5 Crystal structure of a glucose-1-phosphate thymidylyltransferase from burkholderia phymatum bound to 2'-deoxy-thymidine-b-l-rhamnose
66% identity, 98% coverage of query (393 bits)
rhsA / AAC44072.1 glucose-1-phosphate thymidylyltransferase from Sphingomonas sp. S88 (see paper)
65% identity, 98% coverage of query (392 bits)
5ifyA / A4JC15 Crystal structure of glucose-1-phosphate thymidylyltransferase from burkholderia vietnamiensis in complex with 2 -deoxyuridine-5'- monophosphate and 2'-deoxy-thymidine-b-l-rhamnose
64% identity, 98% coverage of query (390 bits)
Som / b2039 dTDP-glucose pyrophosphorylase (EC 2.7.7.24) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
rfbA / P37744 glucose-1-phosphate thymidylyltransferase 1 (EC 2.7.7.24) from Escherichia coli (strain K12) (see 6 papers)
RMLA1_ECOLI / P37744 Glucose-1-phosphate thymidylyltransferase 1; G1P-TT 1; dTDP-glucose pyrophosphorylase 1; dTDP-glucose synthase 1; EC 2.7.7.24 from Escherichia coli (strain K12) (see paper)
rmlA1 / GB|AAC75100.1 glucose-1-phosphate thymidylyltransferase 1; EC 2.7.7.24 from Escherichia coli K12 (see 6 papers)
62% identity, 100% coverage of query (389 bits)
gtt / Q93EK1 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Saccharopolyspora spinosa (see paper)
63% identity, 98% coverage of query (388 bits)
1h5tA Thymidylyltransferase complexed with thymidylyldiphosphate-glucose
63% identity, 99% coverage of query (388 bits)
1h5rA Thymidylyltransferase complexed with thimidine and glucose-1-phospate
63% identity, 99% coverage of query (388 bits)
1h5sB / P37744 Thymidylyltransferase complexed with tmp (see paper)
64% identity, 98% coverage of query (387 bits)
RMLA_SALTY / P26393 Glucose-1-phosphate thymidylyltransferase; dTDP-glucose pyrophosphorylase; Ep; dTDP-glucose synthase; EC 2.7.7.24 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
62% identity, 98% coverage of query (383 bits)
6t37A Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
64% identity, 99% coverage of query (382 bits)
1iinA Thymidylyltransferase complexed with udp-glucose
62% identity, 98% coverage of query (382 bits)
1iimA Thymidylyltransferase complexed with ttp
62% identity, 98% coverage of query (382 bits)
3pkpA Q83s variant of s. Enterica rmla with datp
62% identity, 98% coverage of query (381 bits)
3pkpB Q83s variant of s. Enterica rmla with datp
62% identity, 98% coverage of query (381 bits)
rfbA / A4FPS2 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) (see 2 papers)
61% identity, 98% coverage of query (380 bits)
RMLA3_ECOLX / P55253 Glucose-1-phosphate thymidylyltransferase; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase; EC 2.7.7.24 from Escherichia coli (see paper)
rmlA / AAC63614.1 RmlA from Escherichia coli (see 6 papers)
62% identity, 98% coverage of query (379 bits)
rmlA / AAA16191.1 glucose-1-phosphate thymidyltransferase from Xanthomonas campestris pv. campestris (see 4 papers)
63% identity, 98% coverage of query (377 bits)
3pkqA Q83d variant of s. Enterica rmla with dgtp
61% identity, 98% coverage of query (374 bits)
RMLA_MYCS2 / A0QPF9 Glucose-1-phosphate thymidylyltransferase; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase; EC 2.7.7.24 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
62% identity, 98% coverage of query (363 bits)
6t38A Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
61% identity, 99% coverage of query (363 bits)
RMLA_MYCTU / P9WH13 Glucose-1-phosphate thymidylyltransferase; Glc-1-P thymidylyltransferase; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase; EC 2.7.7.24 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 5 papers)
P9WH13 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Mycobacterium tuberculosis (see paper)
61% identity, 99% coverage of query (362 bits)
Q5EPE6 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Campylobacter jejuni (see paper)
59% identity, 99% coverage of query (362 bits)
6b5eB / P9WH13 Mycobacterium tuberculosis rmla in complex with dtdp-glucose (see paper)
61% identity, 98% coverage of query (361 bits)
6tqgA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor
61% identity, 99% coverage of query (351 bits)
sibI / C0LTM3 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptosporangium sibiricum (see paper)
57% identity, 98% coverage of query (345 bits)
6b5kA Mycobacterium tuberculosis rmla in complex with mg/dttp
60% identity, 98% coverage of query (341 bits)
novV / Q9L9E6 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces niveus (see 2 papers)
56% identity, 100% coverage of query (338 bits)
desIII / Q9ZGH2 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces venezuelae (see paper)
57% identity, 99% coverage of query (336 bits)
gerD / Q331R2 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces sp. KCTC 0041BP (see paper)
54% identity, 98% coverage of query (330 bits)
tylA1 / Q54143 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces fradiae (see 2 papers)
53% identity, 98% coverage of query (297 bits)
oac3 / CAA80332.1 OAC3, partial from Azorhizobium caulinodans (see paper)
66% identity, 73% coverage of query (289 bits)
3hl3A / A0A6L8PCC3 2.76 angstrom crystal structure of a putative glucose-1-phosphate thymidylyltransferase from bacillus anthracis in complex with a sucrose.
46% identity, 82% coverage of query (194 bits)
A0A4Y1W0P1 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Bacillus anthracis (see paper)
46% identity, 82% coverage of query (194 bits)
4ecmA 2.3 angstrom crystal structure of a glucose-1-phosphate thymidylyltransferase from bacillus anthracis in complex with thymidine-5-diphospho-alpha-d-glucose and pyrophosphate
46% identity, 82% coverage of query (194 bits)
RMLA_BACSU / P39629 Glucose-1-phosphate thymidylyltransferase; Spore coat polysaccharide biosynthesis protein SpsI; dTDP-glucose pyrophosphorylase; dTDP-glucose synthase; EC 2.7.7.24 from Bacillus subtilis (strain 168) (see paper)
43% identity, 82% coverage of query (188 bits)
ravd / D1H0J0 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces ravidus (see 2 papers)
37% identity, 83% coverage of query (154 bits)
oleS / Q9RR29 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces antibioticus (see paper)
OLES_STRAT / Q9RR29 Glucose-1-phosphate thymidylyltransferase; EC 2.7.7.24 from Streptomyces antibioticus (see paper)
38% identity, 81% coverage of query (152 bits)
agl11 / D4GU70 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
AGL11_HALVD / D4GU70 Low-salt glycan biosynthesis nucleotidyltransferase Agl11; EC 2.7.7.- from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
37% identity, 90% coverage of query (150 bits)
Q2HR55 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces sp. (see paper)
36% identity, 81% coverage of query (149 bits)
mtmD / Q194R4 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces argillaceus (see paper)
mtmD / CAK50774.1 dTDP-glucose synthase from Streptomyces argillaceus (see 21 papers)
39% identity, 81% coverage of query (148 bits)
Q400H3 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Thermus caldophilus (see paper)
38% identity, 81% coverage of query (147 bits)
dnmL / C6K8M0 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces peucetius subsp. caesius ATCC 27952 (see 2 papers)
C6K8M0 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) from Streptomyces peucetius (see paper)
36% identity, 81% coverage of query (141 bits)
Build an alignment for GFF260 and 82 homologs with ≥ 30% identity
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GLMU_METJA / Q58501 Bifunctional protein GlmU; EC 2.7.7.23; EC 2.3.1.157 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 2 papers)
28% identity, 81% coverage of query (92.4 bits)
ST0452 / Q975F9 multifunctional glucose-1-phosphate thymidylyltransferase/hexosamine-1-phosphate N-acetyltransferase/UDP-N-acetylhexosamine diphosphorylase (EC 2.7.7.24; EC 2.7.7.23; EC 2.7.7.83; EC 2.3.1.157; EC 2.3.1.276) from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (see 2 papers)
S1PNA_SULTO / Q975F9 Bifunctional sugar-1-phosphate nucleotidylyltransferase/acetyltransferase; EC 2.7.7.24; EC 2.7.7.9; EC 2.7.7.83; EC 2.7.7.23; EC 2.3.1.276; EC 2.3.1.157 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see 5 papers)
Q975F9 glucosamine-1-phosphate N-acetyltransferase (EC 2.3.1.157); galactosamine-1-phosphate N-acetyltransferase (EC 2.3.1.276); UDP-N-acetylglucosamine diphosphorylase (EC 2.7.7.23); glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24); aldose-1-phosphate nucleotidyltransferase (EC 2.7.7.37); UDP-N-acetylgalactosamine diphosphorylase (EC 2.7.7.83); UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Sulfurisphaera tokodaii (see 7 papers)
2ggqA / Q975F9 Complex of hypothetical glucose-1-phosphate thymidylyltransferase from sulfolobus tokodaii
28% identity, 81% coverage of query (91.3 bits)
aglF / D4GYH1 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.64) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 2 papers)
AGLF_HALVD / D4GYH1 UTP--glucose-1-phosphate uridylyltransferase AglF; Archaeal glycosylation protein F; EC 2.7.7.9 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 3 papers)
aglF / CAQ51229.1 archaeal glycosylation protein F from Haloferax volcanii (see paper)
30% identity, 71% coverage of query (90.9 bits)
5z09A St0452(y97n)-utp binding form
28% identity, 81% coverage of query (90.9 bits)
Q54800 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Streptococcus pneumoniae (see paper)
cap3C / CAA87405.1 glucosephosphate uridylyltransferase from Streptococcus pneumoniae (see 2 papers)
25% identity, 83% coverage of query (82.8 bits)
3jukA / O25363 The crystal structure of udp-glucose pyrophosphorylase complexed with udp-glucose (see paper)
27% identity, 80% coverage of query (80.9 bits)
3jukD The crystal structure of udp-glucose pyrophosphorylase complexed with udp-glucose
27% identity, 81% coverage of query (80.9 bits)
O25363 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Helicobacter pylori (see paper)
26% identity, 81% coverage of query (79.0 bits)
Q8PK83 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Xanthomonas citri (see paper)
27% identity, 84% coverage of query (78.6 bits)
A0A0H2X8N4 UTP-glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) from Xanthomonas campestris pv. campestris (see paper)
27% identity, 84% coverage of query (78.2 bits)
YNGB_BACSU / O31822 UTP--glucose-1-phosphate uridylyltransferase YngB; Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; UGPase; Uridine diphosphoglucose pyrophosphorylase; EC 2.7.7.9 from Bacillus subtilis (strain 168) (see paper)
26% identity, 72% coverage of query (78.2 bits)
8f73E / Q9I291 Crystal structure of pseudomonas aeruginosa udp-glucose phosphorylase in complex with udp-glucose
26% identity, 81% coverage of query (77.8 bits)
7d73E Cryo-em structure of gmppa/gmppb complex bound to gtp (state i)
24% identity, 84% coverage of query (68.9 bits)
GMPPB_HUMAN / Q9Y5P6 Mannose-1-phosphate guanyltransferase beta; GDP-mannose pyrophosphorylase B; GTP-mannose-1-phosphate guanylyltransferase beta; EC 2.7.7.13 from Homo sapiens (Human) (see 4 papers)
Q9Y5P6 mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) from Homo sapiens (see paper)
7d72K / Q9Y5P6 Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose (see paper)
24% identity, 84% coverage of query (68.9 bits)
7d72E Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose
24% identity, 84% coverage of query (68.9 bits)
5i1fA / A4JT02 Crystal structure of utp-glucose-1-phosphate uridylyltransferase from burkholderia vietnamiensis in complex with uridine-5'-diphosphate- glucose
25% identity, 71% coverage of query (68.2 bits)
2ux8G / Q5FYV5 Crystal structure of sphingomonas elodea atcc 31461 glucose-1- phosphate uridylyltransferase in complex with glucose-1-phosphate. (see paper)
24% identity, 73% coverage of query (67.0 bits)
7whsA / E9BG32 Cryo-em structure of leishmanial gdp-mannose pyrophosphorylase in complex with gtp (see paper)
23% identity, 83% coverage of query (67.0 bits)
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