Searching for up to 100 curated homologs for GFF2617 FitnessBrowser__WCS417:GFF2617 (328 a.a.)
Found high-coverage hits (≥70%) to 89 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ALKR4_ARATH / Q93ZN2 Probable aldo-keto reductase 4; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
43% identity, 99% coverage of query (268 bits)
AKR1_SOYBN / C6TBN2 Probable aldo-keto reductase 1; GmAKR1; EC 1.1.1.- from Glycine max (Soybean) (Glycine hispida) (see paper)
41% identity, 99% coverage of query (251 bits)
PR / Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 2 papers)
PERR_RAUSE / Q3L181 Perakine reductase; EC 1.1.1.317 from Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum) (see 2 papers)
Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 3 papers)
41% identity, 95% coverage of query (238 bits)
STR7_STRTC / A0A3B1EFQ1 Aldo-keto reductase str7; Strobilurin A biosynthesis cluster protein r7; EC 1.1.1.- from Strobilurus tenacellus (see 3 papers)
39% identity, 96% coverage of query (229 bits)
YAKC_SCHPO / Q09923 Aldo-keto reductase yakc [NADP(+)]; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
yak3 aldose reductase YakC from Schizosaccharomyces pombe (see 3 papers)
39% identity, 93% coverage of query (225 bits)
3v0sA / Q3L181 Crystal structure of perakine reductase, founder member of a novel akr subfamily with unique conformational changes during NADPH binding (see paper)
39% identity, 91% coverage of query (210 bits)
F2YCN5 D-xylose reductase (EC 1.1.1.307) from Zymomonas mobilis subsp. mobilis (see paper)
34% identity, 79% coverage of query (167 bits)
PLR1_SCHPO / O14295 Pyridoxal reductase; PL reductase; PL-red; EC 1.1.1.65 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
plr1 / RF|NP_594584.1 pyridoxal reductase Plr1; EC 1.1.1.65 from Schizosaccharomyces pombe (see 3 papers)
31% identity, 95% coverage of query (156 bits)
FDB38_GIBM7 / W7N2Q9 Aldo-keto reductase FVEG_12638; Fusarium detoxification of benzoxazolinone cluster 2 protein FVEG_12638; FDB2 cluster protein FVEG_12638; EC 1.1.1.- from Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) (see 4 papers)
33% identity, 97% coverage of query (154 bits)
GS69_BACSU / P80874 Aldo-keto reductase YhdN; AKR11B; General stress protein 69; GSP69; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 3 papers)
31% identity, 92% coverage of query (153 bits)
FDB25_FUSPC / K3VD70 Aldo-keto reductase FPSE_08125; Fusarium detoxification of benzoxazolinone cluster protein FPSE_08125; FDB cluster protein FPSE_08125; EC 1.1.1.- from Fusarium pseudograminearum (strain CS3096) (Wheat and barley crown-rot fungus) (see 3 papers)
33% identity, 100% coverage of query (152 bits)
8hnqA / A0A6B8QJ47 The structure of a alcohol dehydrogenase akr13b2 with NADP
35% identity, 88% coverage of query (151 bits)
1pz1A / P80874 Structure of NADPH-dependent family 11 aldo-keto reductase akr11b(holo) (see paper)
31% identity, 92% coverage of query (150 bits)
IOLS_BACSU / P46336 Aldo-keto reductase IolS; AKR11A; Vegetative protein 147; VEG147; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 4 papers)
31% identity, 92% coverage of query (147 bits)
1pz0A / P46336 Structure of NADPH-dependent family 11 aldo-keto reductase akr11a(holo) (see paper)
31% identity, 92% coverage of query (147 bits)
Build an alignment for GFF2617 and 15 homologs with ≥ 30% identity
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Q5FQJ0 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans (see paper)
29% identity, 94% coverage of query (144 bits)
YajO / b0419 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli K-12 substr. MG1655 (see 7 papers)
yajO / P77735 1-deoxyxylulose-5-phosphate synthase YajO from Escherichia coli (strain K12) (see 6 papers)
YAJO_ECOLI / P77735 1-deoxyxylulose-5-phosphate synthase YajO; EC 1.1.-.- from Escherichia coli (strain K12) (see 2 papers)
P77735 1-deoxy-D-xylulose-5-phosphate synthase (EC 2.2.1.7) from Escherichia coli (see paper)
33% identity, 90% coverage of query (142 bits)
Gpr / b3001 L-glyceraldehyde 3-phosphate reductase from Escherichia coli K-12 substr. MG1655 (see 9 papers)
gpr / Q46851 L-glyceraldehyde 3-phosphate reductase (EC 1.1.1.21) from Escherichia coli (strain K12) (see 7 papers)
GPR_ECOLI / Q46851 L-glyceraldehyde 3-phosphate reductase; GAP reductase; EC 1.1.1.- from Escherichia coli (strain K12) (see 4 papers)
33% identity, 87% coverage of query (139 bits)
4aubB / Q46851 The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate (see paper)
33% identity, 87% coverage of query (137 bits)
8jwmB / A0A3R7J519 Crystal structure of akrtyl-NADP-tylosin complex (see paper)
35% identity, 89% coverage of query (135 bits)
KCAB_ARATH / O23016 Probable voltage-gated potassium channel subunit beta; K(+) channel subunit beta; Potassium voltage beta 1; KV-beta1; EC 1.1.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
35% identity, 87% coverage of query (133 bits)
8jwkD The second purified state crystal structure of akrtyl
35% identity, 89% coverage of query (132 bits)
8jwoL / A0A3R7J519 Crystal structure of akrtyl-tylosin complex (see paper)
35% identity, 89% coverage of query (131 bits)
PLR2_SCHPO / O94521 Probable pyridoxal reductase 2; PL reductase 2; PL-red 2; EC 1.1.1.65 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
28% identity, 95% coverage of query (130 bits)
8jwkH The second purified state crystal structure of akrtyl
34% identity, 92% coverage of query (130 bits)
3n6qD Crystal structure of yghz from e. Coli
32% identity, 87% coverage of query (129 bits)
YH5B_SCHPO / O94315 Uncharacterized oxidoreductase C215.11c; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
30% identity, 90% coverage of query (127 bits)
6ow0A / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
35% identity, 80% coverage of query (125 bits)
PdxI / b1406 pyridoxine 4-dehydrogenase (EC 1.1.1.65) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
pdxI / P25906 pyridoxal reductase (EC 1.1.1.65) from Escherichia coli (strain K12) (see 5 papers)
PDXI_ECOLI / P25906 Pyridoxine 4-dehydrogenase; EC 1.1.1.65 from Escherichia coli (strain K12) (see 2 papers)
ydbC / MB|P25906 putative oxidoreductase ydbC from Escherichia coli K12 (see paper)
33% identity, 91% coverage of query (125 bits)
YdjG / b1771 NADH-dependent methylglyoxal reductase from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydjG / P77256 NADH-dependent methylglyoxal reductase from Escherichia coli (strain K12) (see 4 papers)
AKRMG_ECOLI / P77256 NADH-specific methylglyoxal reductase; AKR11B2; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
ydjG / RF|NP_416285 uncharacterized oxidoreductase ydjG from Escherichia coli K12 (see paper)
31% identity, 96% coverage of query (125 bits)
AFLE_ASPPU / Q00258 Norsolorinic acid reductase A; Aflatoxin biosynthesis protein E; EC 1.1.1.- from Aspergillus parasiticus (strain ATCC 56775 / NRRL 5862 / SRRC 143 / SU-1) (see 2 papers)
nor / AAC49166.1 norsolorinic acid reductase from Aspergillus parasiticus (see paper)
30% identity, 90% coverage of query (124 bits)
4aubE The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate
31% identity, 87% coverage of query (124 bits)
KCAB_ORYSJ / Q40648 Probable voltage-gated potassium channel subunit beta; K(+) channel subunit beta; EC 1.1.1.- from Oryza sativa subsp. japonica (Rice) (see paper)
34% identity, 87% coverage of query (123 bits)
1ynpB / Q9KE47 Aldo-keto reductase akr11c1 from bacillus halodurans (apo form) (see paper)
29% identity, 92% coverage of query (122 bits)
5t79A / Q8ZNA1 X-ray crystal structure of a novel aldo-keto reductases for the biocatalytic conversion of 3-hydroxybutanal to 1,3-butanediol (see paper)
32% identity, 86% coverage of query (122 bits)
6ow0B / Q194Q1 Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
35% identity, 80% coverage of query (122 bits)
1ynqB Aldo-keto reductase akr11c1 from bacillus halodurans (holo form)
29% identity, 92% coverage of query (122 bits)
3erpA Structure of idp01002, a putative oxidoreductase from and essential gene of salmonella typhimurium
32% identity, 86% coverage of query (122 bits)
YEZB_SCHPO / O14125 Uncharacterized oxidoreductase C3A11.11c; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
30% identity, 78% coverage of query (119 bits)
6hg6A / A0A1S8QGT2 Clostridium beijerinckii aldo-keto reductase cbei_3974 with NADPH (see paper)
30% identity, 86% coverage of query (118 bits)
4aubF / Q46851 The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate (see paper)
31% identity, 87% coverage of query (116 bits)
mtmW / Q194Q1 mithramycin dehydrogenase from Streptomyces argillaceus (see 2 papers)
33% identity, 80% coverage of query (115 bits)
KCAB_SCHPO / O59826 Putative voltage-gated potassium channel subunit beta; K(+) channel subunit beta; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
33% identity, 87% coverage of query (115 bits)
AMT2_ALTAL / Q75ZG2 Aldo-keto reductase AMT2; AM-toxin biosynthesis protein 2; EC 1.1.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
31% identity, 90% coverage of query (115 bits)
1ynpA Aldo-keto reductase akr11c1 from bacillus halodurans (apo form)
28% identity, 92% coverage of query (115 bits)
eryBII / A4F7P4 dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-α-D-allose-forming) from Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) (see 2 papers)
31% identity, 91% coverage of query (114 bits)
8hw0A / A0A6B8QIS5 The structure of akr6d1
31% identity, 87% coverage of query (114 bits)
YI7E_SCHPO / Q9P7U2 Putative aryl-alcohol dehydrogenase C977.14c; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
29% identity, 95% coverage of query (114 bits)
6kikA / Q9X265 Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor tolrestat (see paper)
29% identity, 92% coverage of query (113 bits)
Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima (see 2 papers)
29% identity, 92% coverage of query (113 bits)
6kiyA Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor epalrestat
29% identity, 92% coverage of query (113 bits)
5danA Crystal structure of a novel aldo keto reductase tm1743 from thermotoga maritima in complex with NADP+
29% identity, 92% coverage of query (113 bits)
VRDA_ASPPA / B9WYE6 Versiconal hemiacetal acetate reductase; VHA reductase; EC 1.1.1.353 from Aspergillus parasiticus (see paper)
B9WYE6 versiconal hemiacetal acetate reductase (EC 1.1.1.353) from Aspergillus parasiticus (see paper)
29% identity, 90% coverage of query (112 bits)
KCAB3_XENLA / Q9PTM4 Voltage-gated potassium channel subunit beta-3; K(+) channel subunit beta-3; Kv-beta-3; EC 1.1.1.- from Xenopus laevis (African clawed frog) (see paper)
30% identity, 87% coverage of query (111 bits)
7wf3C / Q13303 Composite map of human kv1.3 channel in apo state with beta subunits (see paper)
30% identity, 93% coverage of query (111 bits)
AFTS1_ALTAL / Q75ZG3 Aldo-keto reductase AFTS1; AF-toxin biosynthesis protein S1; EC 1.1.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 3 papers)
29% identity, 94% coverage of query (110 bits)
KCAB2_HUMAN / Q13303 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; hKvbeta2; EC 1.1.1.- from Homo sapiens (Human) (see 4 papers)
29% identity, 95% coverage of query (110 bits)
GME68_PESMI / A0A5B8YXI2 Aryl-alcohol dehydrogenase GME11368; Dibenzodioxocinones biosynthesis cluster protein GME11368; EC 1.1.1.- from Pestalotiopsis microspora (see 2 papers)
29% identity, 93% coverage of query (110 bits)
KCAB2_MOUSE / P62482 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; Neuroimmune protein F5; EC 1.1.1.- from Mus musculus (Mouse) (see 8 papers)
KCAB2_RAT / P62483 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; EC 1.1.1.- from Rattus norvegicus (Rat) (see 19 papers)
29% identity, 95% coverage of query (110 bits)
KCAB2_BOVIN / Q27955 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; EC 1.1.1.- from Bos taurus (Bovine) (see paper)
29% identity, 95% coverage of query (110 bits)
1exbA Structure of the cytoplasmic beta subunit-t1 assembly of voltage- dependent k channels
29% identity, 93% coverage of query (110 bits)
3eauA Voltage-dependent k+ channel beta subunit in complex with cortisone
29% identity, 93% coverage of query (110 bits)
KCAB2_XENLA / Q9PTM5 Voltage-gated potassium channel subunit beta-2; K(+) channel subunit beta-2; Kv-beta-2; EC 1.1.1.- from Xenopus laevis (African clawed frog) (see paper)
28% identity, 95% coverage of query (109 bits)
CSH1 member of aldo-keto reductase family from Candida albicans (see 5 papers)
31% identity, 83% coverage of query (109 bits)
megBIIb / Q9F833 MegBIIb from Micromonospora megalomicea subsp. nigra (see paper)
32% identity, 88% coverage of query (109 bits)
PK81H_PSEFD / M2YMU7 Aldo-keto reductase MYCFIDRAFT_87468; PKS8-1 gene cluster protein MYCFIDRAFT_87468; EC 1.1.1.- from Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease fungus) (Mycosphaerella fijiensis) (see 2 papers)
30% identity, 96% coverage of query (109 bits)
AUSK_EMENI / C8VQ93 Aldo-keto reductase ausK; Austinoid biosynthesis clusters protein K; EC 1.1.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see 4 papers)
28% identity, 91% coverage of query (107 bits)
AUSK_PENBI / A0A0F7TN16 Aldo-keto reductase ausK; Austinoid biosynthesis clusters protein K; EC 1.1.1.- from Penicillium brasilianum (see paper)
27% identity, 91% coverage of query (107 bits)
AUSK_ASPCI / A0A0U5GHU6 Aldo-keto reductase ausK; Austinoid biosynthesis cluster protein K; EC 1.1.1.- from Aspergillus calidoustus (see 2 papers)
27% identity, 89% coverage of query (107 bits)
KCAB3_HUMAN / O43448 Voltage-gated potassium channel subunit beta-3; K(+) channel subunit beta-3; Kv-beta-3; EC 1.1.1.- from Homo sapiens (Human) (see paper)
29% identity, 87% coverage of query (107 bits)
SAN2_FUSV7 / C7ZBE5 Aldo-keto reductase NECHADRAFT_45914; Sansalvamide biosynthesis cluster protein NECHADRAFT_45914; EC 1.1.1.- from Fusarium vanettenii (strain ATCC MYA-4622 / CBS 123669 / FGSC 9596 / NRRL 45880 / 77-13-4) (Fusarium solani subsp. pisi) (see paper)
27% identity, 94% coverage of query (106 bits)
AAD16_YEAST / Q02895 Putative aryl-alcohol dehydrogenase AAD16; EC 1.1.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
27% identity, 91% coverage of query (104 bits)
KCAB1_HUMAN / Q14722 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Homo sapiens (Human) (see 13 papers)
28% identity, 92% coverage of query (104 bits)
KCAB1_RAT / P63144 Voltage-gated potassium channel subunit beta-1; K(+) channel subunit beta-1; Kv-beta-1; EC 1.1.1.- from Rattus norvegicus (Rat) (see 9 papers)
28% identity, 92% coverage of query (104 bits)
8usuA / A0A8B8PVT3 Crystal structure of l-galactose 1-dehydrogenase of myrciaria dubia in complex with NAD (see paper)
26% identity, 87% coverage of query (97.8 bits)
6ciaA / A6T7Q7 Crystal structure of aldo-keto reductase from klebsiella pneumoniae in complex with NADPH.
27% identity, 91% coverage of query (94.4 bits)
4wghA Crystal structure of aldo/keto reductase from klebsiella pneumoniae in complex with NADP and acetate at 1.8 a resolution
27% identity, 91% coverage of query (94.4 bits)
7eziA / Q2QQV2 Rice l-galactose dehydrogenase (apo form)
27% identity, 92% coverage of query (93.6 bits)
7ezlA Rice l-galactose dehydrogenase (holo form)
27% identity, 92% coverage of query (93.6 bits)
7svqA / Q6BDJ2 Crystal structure of l-galactose dehydrogenase from spinacia oleracea in complex with NAD+ (see paper)
26% identity, 87% coverage of query (91.7 bits)
5c7hA / Q92NR7 Crystal structure of aldo-keto reductase from sinorhizobium meliloti 1021 in complex with NADPH
27% identity, 88% coverage of query (79.7 bits)
4pmjA Crystal structure of a putative oxidoreductase from sinorhizobium meliloti 1021 in complex with NADP
27% identity, 88% coverage of query (79.7 bits)
ARK73_RAT / P38918 Aflatoxin B1 aldehyde reductase member 3; AFB1-AR; Aflatoxin B1 aldehyde reductase member 1; rAFAR1; EC 1.-.-.- from Rattus norvegicus (Rat) (see 2 papers)
28% identity, 83% coverage of query (76.3 bits)
1gveA / P38918 Aflatoxin aldehyde reductase (akr7a1) from rat liver (see paper)
28% identity, 83% coverage of query (75.9 bits)
YgdS / b2834 putative NADP(H)-dependent aldo-keto reductase Tas from Escherichia coli K-12 substr. MG1655 (see 6 papers)
1lqaA / P0A9T4 Tas protein from escherichia coli in complex with NADPH (see paper)
tas protein Tas from Escherichia coli str. K12 substr. MG1655 (see paper)
24% identity, 90% coverage of query (60.8 bits)
P0A9T4 Protein tas from Escherichia coli (strain K12)
24% identity, 90% coverage of query (60.8 bits)
7s5fB / A0A1U9WT24 Crystal structure of mannose-6-phosphate reductase from celery (apium graveolens) leaves with NADP+ and mannonic acid bound (see paper)
25% identity, 92% coverage of query (58.5 bits)
CPRC2_CANPA / Q76L36 NADPH-dependent conjugated polyketone reductase C2; CPR-C2; 2-dehydropantolactone reductase; Ketopantoyl-lactone reductase; EC 1.1.1.-; EC 1.1.1.358 from Candida parapsilosis (Yeast) (see 4 papers)
Q76L36 2-dehydropantolactone reductase (Si-specific) (EC 1.1.1.214); 2-dehydropantolactone reductase (EC 1.1.1.358) from Candida parapsilosis (see 4 papers)
26% identity, 80% coverage of query (45.4 bits)
4h8nA / Q76L36 Crystal structure of conjugated polyketone reductase c2 from candida parapsilosis complexed with NADPH (see paper)
26% identity, 80% coverage of query (45.1 bits)
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