Searching for up to 100 curated homologs for GFF2620 FitnessBrowser__Phaeo:GFF2620 (270 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
33% identity, 83% coverage of query (115 bits)
4zv2A An ancestral arginine-binding protein bound to glutamine
33% identity, 83% coverage of query (115 bits)
TcyJ / b1920 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
tcyJ / P0AEM9 cystine ABC transporter periplasmic binding protein (EC 7.4.2.12) from Escherichia coli (strain K12) (see 13 papers)
TCYJ_ECOLI / P0AEM9 L-cystine-binding protein TcyJ; CBP; Protein FliY; Sulfate starvation-induced protein 7; SSI7 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.3.10 / P0AEM9 Cystine-binding periplasmic protein FLIY aka CysX aka B1920, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 7 papers)
30% identity, 83% coverage of query (104 bits)
5t0wA Crystal structure of the ancestral amino acid-binding protein anccdt- 1, a precursor of cyclohexadienyl dehydratase
32% identity, 80% coverage of query (103 bits)
Build an alignment for GFF2620 and 4 homologs with ≥ 30% identity
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2q2cA Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus
29% identity, 84% coverage of query (101 bits)
2pvuA Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus
29% identity, 84% coverage of query (101 bits)
2q2aA / D0VWX8 Crystal structures of the arginine-, lysine-, histidine-binding protein artj from the thermophilic bacterium geobacillus stearothermophilus (see paper)
29% identity, 84% coverage of query (100 bits)
TCYA_BACSU / P42199 L-cystine-binding protein TcyA from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.3.14 / P42199 TcyA (YckK), component of Uptake system for L-cystine from Bacillus subtilis (see 5 papers)
29% identity, 84% coverage of query (99.8 bits)
SMc00140 L-lysine ABC transporter, substrate-binding component from Sinorhizobium meliloti 1021
30% identity, 94% coverage of query (93.2 bits)
TC 3.A.1.3.23 / Q9HU31 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter periplasmic binding protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
28% identity, 84% coverage of query (92.0 bits)
GlnH / b0811 L-glutamine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 13 papers)
GlnH / P0AEQ3 L-glutamine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli (strain K12) (see 13 papers)
GLNH_ECOLI / P0AEQ3 Glutamine-binding periplasmic protein; GlnBP from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.2 / P0AEQ3 Glutamine-binding periplasmic protein GlnH aka B0811 aka GlnBP, component of Three component ABC L-glutamine porter. The basal ATPase activity (ATP hydrolysis in the absence of substrate) is mainly caused by the docking of the closed-unliganded state of GlnH onto the transporter domain of GlnPQ. Unlike glutamine, arginine binds both GlnH domains, but does not trigger their closing. Comparison of the ATPase activity in nanodiscs with glutamine transport in proteoliposomes suggested that the stoichiometry of ATP per substrate is close to two from Escherichia coli (see 7 papers)
glnH / GB|AAN79369.1 glutamine ABC transporter, periplasmic glutamine-binding protein GlnH from Escherichia coli (see 7 papers)
27% identity, 94% coverage of query (91.3 bits)
AO356_09900 ABC transporter for L-Lysine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
27% identity, 95% coverage of query (89.4 bits)
8eyzA / P0AEQ3 Engineered glutamine binding protein bound to gln and a cobaloxime ligand (see paper)
27% identity, 84% coverage of query (86.3 bits)
Ac3H11_2555 ABC transporter for L-Histidine, periplasmic substrate-binding component 1 from Acidovorax sp. GW101-3H11
28% identity, 83% coverage of query (85.9 bits)
3i6vA / Q5LTV6 Crystal structure of a periplasmic his/glu/gln/arg/opine family- binding protein from silicibacter pomeroyi in complex with lysine
29% identity, 84% coverage of query (83.6 bits)
6svfA / Q9WZ62 Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
27% identity, 84% coverage of query (81.6 bits)
4ohnA / A0A0H2UKY8 Crystal structure of an abc uptake transporter substrate binding protein from streptococcus pneumoniae with bound histidine
26% identity, 85% coverage of query (77.8 bits)
3k4uE / Q7MAG0 Crystal structure of putative binding component of abc transporter from wolinella succinogenes dsm 1740 complexed with lysine
25% identity, 85% coverage of query (76.6 bits)
TC 3.A.1.3.17 / Q8YSA2 Basic amino acid uptake transporter, BgtAB (see paper)
26% identity, 85% coverage of query (76.3 bits)
TC 3.A.1.3.6 / P35120 NocT aka ATU6027 aka AGR_PTI_67, component of Nopaline porter from Agrobacterium tumefaciens (see 3 papers)
24% identity, 94% coverage of query (73.6 bits)
HISJ_CAMJE / Q46125 Probable histidine-binding protein; HBP; p29 from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) (see paper)
26% identity, 81% coverage of query (73.2 bits)
2pyyB / D0VWX9 Crystal structure of the glur0 ligand-binding core from nostoc punctiforme in complex with (l)-glutamate (see paper)
27% identity, 75% coverage of query (72.8 bits)
BPHYT_RS24000 L-histidine ABC transporter, substrate-binding component from Burkholderia phytofirmans PsJN
27% identity, 84% coverage of query (72.0 bits)
4g4pA / Q837S0 Crystal structure of glutamine-binding protein from enterococcus faecalis at 1.5 a (see paper)
25% identity, 85% coverage of query (71.6 bits)
AO353_03055 ABC transporter for L-Arginine and L-Citrulline, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
25% identity, 91% coverage of query (70.9 bits)
5ovzA / P35120 High resolution structure of the pbp noct in complex with nopaline (see paper)
23% identity, 84% coverage of query (70.9 bits)
5otcA Structure of the periplasmic binding protein (pbp) noct from agrobacterium tumefaciens c58 in complex with noroctopinic acid.
23% identity, 84% coverage of query (70.5 bits)
5otaA Structure of the periplasmic binding protein (pbp) noct from agrobacterium tumefaciens c58 in complex with octopinic acid
23% identity, 84% coverage of query (70.5 bits)
5ot9A Structure of the periplasmic binding protein (pbp) noct from a.Tumefaciens c58 in complex with histopine.
23% identity, 84% coverage of query (70.5 bits)
4powA Structure of the pbp noct in complex with pyronopaline
23% identity, 84% coverage of query (70.5 bits)
AO356_18700 L-Arginine ABC transporter, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
24% identity, 91% coverage of query (69.7 bits)
Pf6N2E2_5660 L-Arginine ABC transporter, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
24% identity, 91% coverage of query (69.7 bits)
ARTP_BACSU / P54535 Arginine-binding extracellular protein ArtP from Bacillus subtilis (strain 168) (see paper)
25% identity, 84% coverage of query (68.9 bits)
ARGBP_PSEAE / G3XD47 L-arginine-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 3 papers)
TC 3.A.1.3.11 / O50181 AotJ aka PA0888, component of Arginine/ornithine (but not lysine) porter from Pseudomonas aeruginosa (see 2 papers)
27% identity, 90% coverage of query (68.6 bits)
AAC45332.1 high affinity cystine binding protein from Lactobacillus reuteri (see 4 papers)
23% identity, 97% coverage of query (68.6 bits)
HP15_3031 L-arginine ABC transporter, periplasmic substrate-binding component ArtJ/HisJ/ArtI/AotJ/ArgT from Marinobacter adhaerens HP15
26% identity, 93% coverage of query (68.2 bits)
5itoA Structure of the periplasmic binding protein m117n-noct from a. Tumefaciens in complex with octopine
23% identity, 84% coverage of query (67.4 bits)
PP_3593 L-lysine and D-lysine ABC transporter, substrate-binding component from Pseudomonas putida KT2440
25% identity, 82% coverage of query (67.0 bits)
Pf1N1B4_3431 ABC transporter for L-Arginine and L-Citrulline, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N1B4
25% identity, 91% coverage of query (66.6 bits)
5l9oA Crystal structure of agrobacterium tumefaciens c58 strain pbp soca in complex with glucopine
30% identity, 76% coverage of query (66.6 bits)
5lomB / Q7D447 Crystal structure of the pbp soca from agrobacterium tumefaciens c58 in complex with dfg at 1.5 a resolution (see paper)
30% identity, 76% coverage of query (66.2 bits)
GLNH_BACSU / O34563 ABC transporter glutamine-binding protein GlnH from Bacillus subtilis (strain 168) (see paper)
26% identity, 78% coverage of query (66.2 bits)
4ymxA / Q8RCC4 Crystal structure of the substrate binding protein of an amino acid abc transporter (see paper)
26% identity, 80% coverage of query (66.2 bits)
5l9oB Crystal structure of agrobacterium tumefaciens c58 strain pbp soca in complex with glucopine
30% identity, 76% coverage of query (66.2 bits)
HisJ / b2309 histidine ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
HISJ_ECOLI / P0AEU0 Histidine-binding periplasmic protein; HBP from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.29 / P0AEU0 Histidine-binding periplasmic protein, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
hisJ / GB|AAC75369.1 histidine ABC transporter, periplasmic histidine-binding protein HisJ from Escherichia coli (see 7 papers)
24% identity, 84% coverage of query (65.5 bits)
YXEM_BACSU / P54952 Probable amino-acid-binding protein YxeM from Bacillus subtilis (strain 168) (see 2 papers)
23% identity, 81% coverage of query (64.7 bits)
1hslA / P0AEU0 Refined 1.89 angstroms structure of the histidine-binding protein complexed with histidine and its relationship with many other active transport(slash)chemosensory receptors (see paper)
24% identity, 84% coverage of query (64.7 bits)
3vvfA Crystal structure of ttc0807 complexed with arginine
26% identity, 84% coverage of query (64.3 bits)
3vveA Crystal structure of ttc0807 complexed with lysine
26% identity, 84% coverage of query (64.3 bits)
3vvdA / Q72JG5 Crystal structure of ttc0807 complexed with ornithine (see paper)
26% identity, 84% coverage of query (64.3 bits)
HISJ_SALTY / P02910 Histidine-binding periplasmic protein; HBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
hisJ / GB|AAV76512.1 histidine ABC transporter, periplasmic histidine-binding protein HisJ from Salmonella enterica subsp. enterica serovar Typhimurium (see 5 papers)
24% identity, 84% coverage of query (64.3 bits)
3vv5A Crystal structure of ttc0807 complexed with (s)-2-aminoethyl-l- cysteine (aec)
26% identity, 84% coverage of query (64.3 bits)
8gu1A Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with pimozide
23% identity, 83% coverage of query (60.8 bits)
6aalA Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with arginine
23% identity, 83% coverage of query (60.8 bits)
6a80A Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with cystine
23% identity, 83% coverage of query (60.8 bits)
8gtuA / C6XGT2 Crystal structure of putative amino acid binding periplasmic abc transporter protein from candidatus liberibacter asiaticus in complex with clidinium (see paper)
23% identity, 83% coverage of query (60.8 bits)
5orgA / P0A4F8 Structure of the periplasmic binding protein (pbp) occj from a. Tumefaciens b6 in complex with octopine. (see paper)
23% identity, 85% coverage of query (58.9 bits)
8b5dA Exploring the ligand binding and conformational dynamics of receptor domain 1 of the abc transporter glnpq
26% identity, 83% coverage of query (57.8 bits)
ARGT_SALTY / P02911 Lysine/arginine/ornithine-binding periplasmic protein; LAO-binding protein from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 6 papers)
argT / RF|NP_461297.1 lysine/arginine/ornithine ABC transporter, periplasmic lysine/arginine/ornithine-binding protein ArgT from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
25% identity, 91% coverage of query (57.8 bits)
4zefA / Q837S0 Crystal structure of substrate binding domain 2 (sbd2) of abc transporter glnpq from enterococcus faecalis
26% identity, 82% coverage of query (57.0 bits)
6fxgB / Q9CES5 Crystal structure of substrate binding domain 1 (sbd1) of abc transporter glnpq in complex with asparagine
26% identity, 83% coverage of query (56.2 bits)
8b5eA Exploring the ligand binding and conformational dynamics of receptor domain 1 of the abc transporter glnpq
26% identity, 83% coverage of query (56.2 bits)
2ylnA / Q5F9M1 Crystal structure of the l-cystine solute receptor of neisseria gonorrhoeae in the closed conformation (see paper)
26% identity, 83% coverage of query (56.2 bits)
4h5fA Crystal structure of an amino acid abc transporter substrate-binding protein from streptococcus pneumoniae canada mdr_19a bound to l- arginine, form 1
24% identity, 81% coverage of query (56.2 bits)
1lstA Three-dimensional structures of the periplasmic lysine-, arginine-, ornithine-binding protein with and without a ligand
24% identity, 83% coverage of query (52.8 bits)
1lahE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein
24% identity, 83% coverage of query (52.8 bits)
1lagE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein
24% identity, 83% coverage of query (52.8 bits)
1lafE / P02911 Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein (see paper)
24% identity, 83% coverage of query (52.8 bits)
5owfA Structure of a lao-binding protein mutant with glutamine
24% identity, 83% coverage of query (52.4 bits)
3fasA / P19493 X-ray structure of iglur4 flip ligand-binding core (s1s2) in complex with (s)-glutamate at 1.40a resolution (see paper)
22% identity, 84% coverage of query (51.6 bits)
8i0bA The crystal structure of human glutamate receptor 2 in complex with lt-102
22% identity, 75% coverage of query (51.2 bits)
2xhdA Crystal structure of n-((2s)-5-(6-fluoro-3-pyridinyl)-2,3- dihydro-1h-inden-2-yl)-2-propanesulfonamide in complex with the ligand binding domain of the human glua2 receptor
22% identity, 75% coverage of query (51.2 bits)
3tqlA / Q83E49 Structure of the amino acid abc transporter, periplasmic amino acid- binding protein from coxiella burnetii. (see paper)
23% identity, 83% coverage of query (51.2 bits)
4u1oA Glua2flip slbd complexed with kainate and (r,r)-2b crystal form c
22% identity, 75% coverage of query (50.8 bits)
3pmwA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
22% identity, 75% coverage of query (50.4 bits)
3o6hA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
22% identity, 75% coverage of query (50.4 bits)
4fatA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
22% identity, 75% coverage of query (50.4 bits)
3pmxA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
22% identity, 75% coverage of query (50.4 bits)
3pmvA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
22% identity, 75% coverage of query (50.4 bits)
3o6iA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
22% identity, 75% coverage of query (50.4 bits)
3o6gA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
22% identity, 75% coverage of query (50.4 bits)
3o29A Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
22% identity, 75% coverage of query (50.4 bits)
3o28A Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
22% identity, 75% coverage of query (50.4 bits)
5i59B Glutamate- and glycine-bound glun1/glun2a agonist binding domains with mpx 007
23% identity, 89% coverage of query (50.4 bits)
3o2aA Ligand-binding domain of glua2 (flip) ionotropic glutamate receptor in complex with an allosteric modulator
22% identity, 75% coverage of query (50.4 bits)
8hqrA / Q4FLC2 Crystal structure of the arginine-/lysine-binding protein sar11_1210 from 'candidatus pelagibacter ubique' htcc1062 bound to arginine
23% identity, 84% coverage of query (50.4 bits)
4nf5B Crystal structure of glun1/glun2a ligand-binding domain in complex with glycine and d-ap5
24% identity, 83% coverage of query (50.4 bits)
6uzgB Crystal structure of glun1/glun2a-4m mutant ligand-binding domain in complex with glycine and homoquinolinic acid
24% identity, 82% coverage of query (50.1 bits)
6odlA Crystal structure of glun2a agonist binding domain with 4-butyl-(s)- ccg-iv
24% identity, 82% coverage of query (49.3 bits)
5vihB Crystal structure of glun1/glun2a nmda receptor agonist binding domains with glycine and antagonist, 4-fluorophenyl-acepc
23% identity, 83% coverage of query (49.3 bits)
2a5sA Crystal structure of the nr2a ligand binding core in complex with glutamate
24% identity, 82% coverage of query (49.3 bits)
4uq6B / P19491 Electron density map of glua2em in complex with ly451646 and glutamate (see paper)
22% identity, 76% coverage of query (49.3 bits)
4jwxA Glun2a ligand-binding core in complex with propyl-nhp5g
24% identity, 82% coverage of query (49.3 bits)
5vijB Crystal structure of glun1/glun2a nmda receptor agonist binding domains with glycine and antagonist, 4-bromophenyl-acepc
24% identity, 82% coverage of query (49.3 bits)
3en3A Crystal structure of the glur4 ligand-binding domain in complex with kainate
22% identity, 75% coverage of query (48.9 bits)
6usvB Crystal structure of glun1/glun2a ligand-binding domain in complex with glycine and sdz 220-040
24% identity, 82% coverage of query (48.9 bits)
5viiB Crystal structure of glun1/glun2a nmda receptor agonist binding domains with glycine and antagonist, 4-(3-fluoropropyl)phenyl-acepc
24% identity, 82% coverage of query (48.9 bits)
5i56B Agonist-bound glun1/glun2a agonist binding domains with tcn201
24% identity, 82% coverage of query (48.9 bits)
5dexB Crystal structure of glun1/glun2a nmda receptor agonist binding domains with glycine and antagonist, phenyl-acepc
24% identity, 82% coverage of query (48.9 bits)
6ovdB Crystal structure of glun1/glun2a nmda receptor agonist binding domains with glycine and antagonist, 3-ethylphenyl-acepc
24% identity, 82% coverage of query (48.9 bits)
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Lawrence Berkeley National Laboratory