Searching for up to 100 curated homologs for GFF2806 FitnessBrowser__WCS417:GFF2806 (523 a.a.)
Found high-coverage hits (≥70%) to 59 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
lhpG / Q88NF5 α-ketoglutaric semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
78% identity, 100% coverage of query (801 bits)
KGSD3_AZOBR / Q08IB7 Alpha-ketoglutaric semialdehyde dehydrogenase 3; alphaKGSA dehydrogenase 3; 2,5-dioxovalerate dehydrogenase 3; KGSADH-III; EC 1.2.1.26 from Azospirillum brasilense (see paper)
Q08IB7 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see paper)
64% identity, 99% coverage of query (625 bits)
KGSD2_AZOBR / Q08IC0 Alpha-ketoglutaric semialdehyde dehydrogenase 2; alphaKGSA dehydrogenase 2; 2,5-dioxovalerate dehydrogenase 2; KGSADH-II; EC 1.2.1.26 from Azospirillum brasilense (see paper)
Q08IC0 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Azospirillum brasilense (see paper)
63% identity, 100% coverage of query (617 bits)
Ga0059261_1896 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Sphingomonas koreensis DSMZ 15582
60% identity, 97% coverage of query (559 bits)
ACIAD0131 / Q6FFQ0 α-ketoglutarate semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
KGSDH_ACIAD / Q6FFQ0 Alpha-ketoglutaric semialdehyde dehydrogenase; alphaKGSA dehydrogenase; 2,5-dioxovalerate dehydrogenase; EC 1.2.1.26 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ0 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Acinetobacter baylyi (see paper)
51% identity, 99% coverage of query (494 bits)
HSERO_RS00735 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Herbaspirillum seropedicae SmR1
51% identity, 100% coverage of query (486 bits)
PS417_11015 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas simiae WCS417
55% identity, 87% coverage of query (484 bits)
Q88GW5 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Pseudomonas putida (see paper)
54% identity, 88% coverage of query (481 bits)
kgsD / Q9I1Q0 2-ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
55% identity, 88% coverage of query (478 bits)
Pf6N2E2_612 Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) from Pseudomonas fluorescens FW300-N2E2
50% identity, 99% coverage of query (466 bits)
aldH / AAA89078.1 fatty aldehyde dehydrogenase from Vibrio harveyi (see paper)
49% identity, 95% coverage of query (458 bits)
1eyyA / Q56694 Crystal structure of the NADP+ dependent aldehyde dehydrogenase from vibrio harveyi. (see paper)
49% identity, 95% coverage of query (458 bits)
Build an alignment for GFF2806 and 12 homologs with ≥ 30% identity
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tsaD / P94682 TsaD (EC 1.2.1.62) from Comamonas testosteroni (see paper)
TSAD1_COMTE / P94682 4-(hydroxymethyl)benzenesulfonate dehydrogenase TsaD1; Toluenesulfonate aldehyde dehydrogenase TsaD; EC 1.1.1.257 from Comamonas testosteroni (Pseudomonas testosteroni) (see 2 papers)
29% identity, 92% coverage of query (84.3 bits)
5ur2B / Q6MNK1 Crystal structure of proline utilization a (puta) from bdellovibrio bacteriovorus inactivated by n-propargylglycine (see paper)
26% identity, 84% coverage of query (76.3 bits)
VDH_CORGL / Q8NMB0 Vanillin dehydrogenase; Aromatic aldehyde dehydrogenase; EC 1.2.1.67; EC 1.2.1.64; EC 1.2.1.96 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
Q8NMB0 vanillin dehydrogenase (EC 1.2.1.67) from Corynebacterium glutamicum (see paper)
27% identity, 77% coverage of query (75.1 bits)
padA / CAA66106.1 phenylacetaldehyde dehydrogenase from Escherichia coli (see paper)
27% identity, 78% coverage of query (74.3 bits)
Q6BD86 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Zoysia tenuifolia (see paper)
28% identity, 75% coverage of query (74.3 bits)
Q155V4 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda salsa (see paper)
Q8W5A1 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Suaeda liaotungensis (see 2 papers)
24% identity, 79% coverage of query (73.9 bits)
Q65NN2 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Bacillus licheniformis (see paper)
24% identity, 88% coverage of query (73.6 bits)
Q6BD93 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Zoysia tenuifolia (see paper)
27% identity, 75% coverage of query (73.6 bits)
YdbG / b1385 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
feaB / P80668 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli (strain K12) (see 10 papers)
P80668 phenylacetaldehyde dehydrogenase (EC 1.2.1.39) from Escherichia coli (see 3 papers)
27% identity, 78% coverage of query (72.0 bits)
BADH_SPIOL / P17202 Aminoaldehyde dehydrogenase BADH; 4-trimethylammoniobutyraldehyde dehydrogenase BADH; Aminobutyraldehyde dehydrogenase BADH; Betaine aldehyde dehydrogenase; SoBADH; EC 1.2.1.-; EC 1.2.1.47; EC 1.2.1.19; EC 1.2.1.8 from Spinacia oleracea (Spinach) (see 5 papers)
P17202 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Spinacia oleracea (see 3 papers)
24% identity, 83% coverage of query (71.2 bits)
xacF / D4GP41 α-ketoglutarate semialdehyde dehydrogenase subunit (EC 1.2.1.26) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see paper)
KGSDH_HALVD / D4GP41 Alpha-ketoglutarate semialdehyde dehydrogenase; KGSADH; EC 1.2.1.26 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
27% identity, 88% coverage of query (71.2 bits)
AADH2_MAIZE / C6KEM4 Aminoaldehyde dehydrogenase 2; ZmAMADH2; 4-trimethylammoniobutyraldehyde dehydrogenase AMADH2; Aminobutyraldehyde dehydrogenase AMADH2; Gamma-guanidinobutyraldehyde dehydrogenase AMADH2; EC 1.2.1.-; EC 1.2.1.47; EC 1.2.1.19; EC 1.2.1.54 from Zea mays (Maize) (see paper)
C6KEM4 aminobutyraldehyde dehydrogenase (EC 1.2.1.19) from Zea mays (see paper)
27% identity, 75% coverage of query (70.5 bits)
ALD4 / P46367 potassium-activated aldehyde dehydrogenase, mitochondrial (EC 1.2.1.4; EC 1.2.1.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 2 papers)
ALDH4_YEAST / P46367 Potassium-activated aldehyde dehydrogenase, mitochondrial; K(+)-activated acetaldehyde dehydrogenase; K(+)-ACDH; EC 1.2.1.-; EC 1.2.1.4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
P46367 aldehyde dehydrogenase [NAD(P)+] (EC 1.2.1.5) from Saccharomyces cerevisiae (see paper)
24% identity, 93% coverage of query (70.1 bits)
Q94IC0 betaine-aldehyde dehydrogenase (EC 1.2.1.8) from Hordeum vulgare (see paper)
24% identity, 79% coverage of query (69.7 bits)
Q97XA5 succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79); glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) from Saccharolobus solfataricus (see 2 papers)
25% identity, 78% coverage of query (69.3 bits)
xylA / A0A0H3C801 2,5-dioxovalerate dehydrogenase (EC 1.2.1.26) from Caulobacter vibrioides (strain NA1000 / CB15N) (see 6 papers)
27% identity, 81% coverage of query (68.9 bits)
8hapB Crystal structure of thermostable acetaldehyde dehydrogenase from hyperthermophilic archaeon sulfolobus tokodaii
24% identity, 78% coverage of query (67.4 bits)
8hapA / Q976X5 Crystal structure of thermostable acetaldehyde dehydrogenase from hyperthermophilic archaeon sulfolobus tokodaii (see paper)
24% identity, 78% coverage of query (67.4 bits)
5ekcE / G7VCG0 Thermostable aldehyde dehydrogenase from pyrobaculum sp.1860 complexed with NADP+
25% identity, 73% coverage of query (63.9 bits)
2opxA Crystal structure of lactaldehyde dehydrogenase from escherichia coli
25% identity, 80% coverage of query (63.9 bits)
5ek6A Thermostable aldehyde dehydrogenase from pyrobaculum sp. 1860 complexed with NADP and isobutyraldehyde
25% identity, 73% coverage of query (63.9 bits)
4h73A Thermostable aldehyde dehydrogenase from pyrobaculum sp. Complexed with NADP+
25% identity, 73% coverage of query (63.9 bits)
AL2C4_ARATH / Q56YU0 Aldehyde dehydrogenase family 2 member C4; ALDH1a; Protein REDUCED EPIDERMAL FLUORESCENCE 1; EC 1.2.1.3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
25% identity, 79% coverage of query (60.1 bits)
5izdA / Q9HK01 Wild-type glyceraldehyde dehydrogenase from thermoplasma acidophilum in complex with NADP
23% identity, 84% coverage of query (59.7 bits)
AADH2_PEA / Q93YB2 Aminoaldehyde dehydrogenase 2, peroxisomal; PsAMADH2; Aminobutyraldehyde dehydrogenase AMADH2; Gamma-guanidinobutyraldehyde dehydrogenase AMADH2; EC 1.2.1.-; EC 1.2.1.19; EC 1.2.1.54 from Pisum sativum (Garden pea) (Lathyrus oleraceus) (see 2 papers)
Q93YB2 aminobutyraldehyde dehydrogenase (EC 1.2.1.19) from Pisum sativum (see 2 papers)
26% identity, 74% coverage of query (57.0 bits)
3iwjA / Q93YB2 Crystal structure of aminoaldehyde dehydrogenase 2 from pisum sativum (psamadh2) (see paper)
26% identity, 74% coverage of query (56.6 bits)
3efvA / Q8ZPI3 Crystal structure of a putative succinate-semialdehyde dehydrogenase from salmonella typhimurium lt2 with bound NAD (see paper)
25% identity, 82% coverage of query (56.2 bits)
O14293 Putative aldehyde dehydrogenase-like protein C9E9.09c; EC 1.2.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
23% identity, 86% coverage of query (55.1 bits)
4go4A / C1I208 Crystal structure of pnpe in complex with nicotinamide adenine dinucleotide
25% identity, 71% coverage of query (53.1 bits)
4wb9A Human aldh1a1 complexed with nadh
24% identity, 81% coverage of query (51.2 bits)
ALDH1A1 / P00352 retinal dehydrogenase 1 (EC 1.2.1.36) from Homo sapiens (see 10 papers)
AL1A1_HUMAN / P00352 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Homo sapiens (Human) (see 7 papers)
P00352 retinal dehydrogenase (EC 1.2.1.36) from Homo sapiens (see 6 papers)
24% identity, 81% coverage of query (50.8 bits)
7um9A Human aldh1a1 with bound compound cm38
24% identity, 81% coverage of query (50.8 bits)
5l2oA Crystal structure of aldh1a1 in complex with buc22
24% identity, 81% coverage of query (50.8 bits)
5l2nA Structure of aldh1a1 in complex with buc25
24% identity, 81% coverage of query (50.8 bits)
5l2mA Structure of aldh1a1 in complex with buc11
24% identity, 81% coverage of query (50.8 bits)
4wpnA Structure of human aldh1a1 with inhibitor cm053
24% identity, 81% coverage of query (50.8 bits)
5teiA Structure of human aldh1a1 with inhibitor cm039
24% identity, 81% coverage of query (50.4 bits)
4x4lA Structure of human aldh1a1 with inhibitor cm037
24% identity, 81% coverage of query (50.4 bits)
7jwwA Crystal structure of human aldh1a1 bound to compound (r)-28
24% identity, 81% coverage of query (50.4 bits)
7jwvA Crystal structure of human aldh1a1 bound to compound (r)-28
24% identity, 81% coverage of query (50.4 bits)
7jwuA Crystal structure of human aldh1a1 bound to compound (r)-28
24% identity, 81% coverage of query (50.4 bits)
7jwtA Crystal structure of human aldh1a1 bound to compound (r)-28
24% identity, 81% coverage of query (50.4 bits)
7jwsA Crystal structure of human aldh1a1 bound to compound (r)-28
24% identity, 81% coverage of query (50.4 bits)
6dumA Aldh1a1 n121s in complex with 6-{[(3-fluorophenyl)methyl]sulfanyl}-2- (oxetan-3-yl)-5-phenyl-2,5-dihydro-4h-pyrazolo[3,4-d]pyrimidin-4-one (compound 13g)
24% identity, 81% coverage of query (50.4 bits)
4wp7A Structure of human aldh1a1 with inhibitor cm026
24% identity, 81% coverage of query (50.4 bits)
4zz7A / G5CZI2 Crystal structure of methylmalonate-semialdehyde dehydrogenase (dddc) from oceanimonas doudoroffii (see paper)
23% identity, 81% coverage of query (48.1 bits)
AL1A1_HORSE / P15437 Aldehyde dehydrogenase 1A1; 3-deoxyglucosone dehydrogenase; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; Retinal dehydrogenase 1; RALDH 1; RalDH1; EC 1.2.1.19; EC 1.2.1.28; EC 1.2.1.3; EC 1.2.1.36 from Equus caballus (Horse) (see paper)
24% identity, 81% coverage of query (47.8 bits)
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Lawrence Berkeley National Laboratory