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Searching for up to 100 curated homologs for GFF2860 FitnessBrowser__Marino:GFF2860 (672 a.a.)

Found high-coverage hits (≥70%) to 17 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.5.26 / P63395 Uncharacterized ABC transporter ATP-binding protein Rv1281c/MT1318, component of The glutathione transporter, OppA (Dasgupta et al., 2010). OppA binds glutathione and the nanopeptide, bradykinin. Also regulates cytokine release, apoptosis and the innate immune response of macrophages infected with M. tuberculosis from Mycobacterium tuberculosis (see 2 papers)
    43% identity, 89% coverage of query (470 bits)

8j5qD / P9WQJ5 Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- translocation state (see paper)
    43% identity, 89% coverage of query (468 bits)

GsiA / b0829 glutathione ABC transporter ATP binding subunit GsiA (EC 7.4.2.10) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
gsiA / P75796 glutathione ABC transporter ATP binding subunit GsiA (EC 7.4.2.10) from Escherichia coli (strain K12) (see 3 papers)
GSIA_ECOLI / P75796 Glutathione import ATP-binding protein GsiA; EC 7.4.2.10 from Escherichia coli (strain K12) (see paper)
P75796 ABC-type glutathione transporter (EC 7.4.2.10) from Escherichia coli (see paper)
TC 3.A.1.5.11 / P75796 Hypothetical ABC transporter ATP-binding protein yliA, component of Glutathione porter, YliABCD or GsiABCD from Escherichia coli (see 4 papers)
    42% identity, 93% coverage of query (466 bits)

8j5tD Cryo-em structure of mycobacterium tuberculosis oppabcd in the catalytic intermediate state
    42% identity, 89% coverage of query (465 bits)

8j5sD Cryo-em structure of mycobacterium tuberculosis oppabcd in the pre- catalytic intermediate state
    42% identity, 89% coverage of query (465 bits)

Q8ZQM4 ABC-type glutathione transporter (EC 7.4.2.10) from Salmonella enterica subsp. enterica serovar Typhimurium (see paper)
    43% identity, 92% coverage of query (463 bits)

TC 3.A.1.5.23 / Q9F9T4 EppD, component of The Ethylene diamine tetraacetate (EDTA) uptake porter, EppABCD (see 2 papers)
    41% identity, 88% coverage of query (409 bits)

TC 3.A.1.5.8 / Q97UG5 MalK, component of Maltose and maltooligosaccharide porter from Sulfolobus solfataricus (see paper)
    34% identity, 91% coverage of query (358 bits)

Build an alignment

Build an alignment for GFF2860 and 8 homologs with ≥ 30% identity

Select sequences

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Change minimum %identity:

Additional hits (identity < 30%)

P0A9U3 Probable ATP-binding protein YbiT from Escherichia coli (strain K12)
    24% identity, 81% coverage of query (95.1 bits)

YbiT / b0820 putative ATP-binding protein YbiT from Escherichia coli K-12 substr. MG1655 (see 7 papers)
YBIT_ECOL6 / P0A9U4 Probable ATP-binding protein YbiT from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
ybiT / MB|P0A9U3 uncharacterized ABC transporter ATP-binding protein ybiT from Escherichia coli K12 (see 2 papers)
    24% identity, 81% coverage of query (95.1 bits)

3j5sD / P0A9W3 Etta binds to ribosome exit site and regulates translation by restricting ribosome and tRNA dynamics (see paper)
    23% identity, 78% coverage of query (94.0 bits)

YjjK / b4391 energy-dependent translational throttle protein EttA from Escherichia coli K-12 substr. MG1655 (see 9 papers)
ETTA_ECOLI / P0A9W3 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Escherichia coli (strain K12) (see 2 papers)
CH_004211 ABC transporter, ATP-binding protein YjiK from Escherichia coli K12 (see paper)
    23% identity, 78% coverage of query (94.0 bits)

ETTA_ECOL6 / A0A0H2VFI8 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see paper)
    23% identity, 78% coverage of query (90.9 bits)

VMLR_BACSU / P39115 Ribosome protection protein VmlR; Multidrug resistance system ATP-binding protein VmlR from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.121.3 / P39115 Antibiotic (virginiamycin and lincomycin) resistance protein, VmlR from Bacillus subtilis (see paper)
    22% identity, 80% coverage of query (86.3 bits)

6ha8V / P39115 6ha8V (see paper)
    21% identity, 79% coverage of query (80.9 bits)

ETTA_MYCTU / P9WQK3 Energy-dependent translational throttle protein EttA; Translational regulatory factor EttA; EC 3.6.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    24% identity, 77% coverage of query (79.7 bits)

7mscx 70SIC in complex with MtbEttA at Pre_R0 state
    24% identity, 77% coverage of query (79.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory