Searching for up to 100 curated homologs for GFF2883 FitnessBrowser__Phaeo:GFF2883 (97 a.a.)
Found high-coverage hits (≥70%) to 11 curated proteins.
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PHS_DROME / O76454 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Drosophila melanogaster (Fruit fly) (see paper)
49% identity, 98% coverage of query (104 bits)
PHS_MOUSE / P61458 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Mus musculus (Mouse) (see paper)
52% identity, 96% coverage of query (100 bits)
PCBD1 / P61457 Pterin-4-alpha-carbinolamine dehydratase (EC 4.2.1.96) from Homo sapiens (see paper)
PHS_HUMAN / P61457 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Homo sapiens (Human) (see 5 papers)
PHS_RAT / P61459 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Rattus norvegicus (Rat) (see 7 papers)
51% identity, 96% coverage of query (99.8 bits)
1dcpA Dcoh, a bifunctional protein-binding transcriptional coactivator, complexed with biopterin
51% identity, 96% coverage of query (99.8 bits)
1f93A / P61459 Crystal structure of a complex between the dimerization domain of hnf-1 alpha and the coactivator dcoh (see paper)
51% identity, 96% coverage of query (99.4 bits)
PHS_CHICK / O73930 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; cDcoH; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Gallus gallus (Chicken) (see paper)
51% identity, 96% coverage of query (98.6 bits)
PHS2_MOUSE / Q9CZL5 Pterin-4-alpha-carbinolamine dehydratase 2; PHS 2; 4-alpha-hydroxy-tetrahydropterin dehydratase 2; DcoH-like protein DCoHm; Dimerization cofactor of hepatocyte nuclear factor 1 from muscle; HNF-1-alpha dimerization cofactor; EC 4.2.1.96 from Mus musculus (Mouse) (see paper)
50% identity, 93% coverage of query (98.2 bits)
PCBD2 / Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2 (EC 4.2.1.96) from Homo sapiens (see 3 papers)
PHS2_HUMAN / Q9H0N5 Pterin-4-alpha-carbinolamine dehydratase 2; PHS 2; 4-alpha-hydroxy-tetrahydropterin dehydratase 2; DcoH-like protein DCoHm; Dimerization cofactor of hepatocyte nuclear factor 1 from muscle; HNF-1-alpha dimerization cofactor; EC 4.2.1.96 from Homo sapiens (Human) (see paper)
Q9H0N5 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Homo sapiens (see paper)
47% identity, 96% coverage of query (96.7 bits)
2v6tB / Q2Q449 Crystal structure of a complex of pterin-4a-carbinolamine dehydratase from toxoplasma gondii with 7,8-dihydrobiopterin (see paper)
45% identity, 75% coverage of query (78.2 bits)
Q2Q449 4a-hydroxytetrahydrobiopterin dehydratase (EC 4.2.1.96) from Toxoplasma gondii (see paper)
45% identity, 75% coverage of query (78.2 bits)
PHS_SCHPO / O42658 Pterin-4-alpha-carbinolamine dehydratase; PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Overlapping meiotic transcript 2; Pterin carbinolamine dehydratase; PCD; EC 4.2.1.96 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
omt2 / RF|NP_594610.1 4-alpha-hydroxytetrahydrobiopterin dehydratase (predicted); EC 4.2.1.96 from Schizosaccharomyces pombe (see 2 papers)
42% identity, 78% coverage of query (77.4 bits)
Build an alignment for GFF2883 and 11 homologs with ≥ 30% identity
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Lawrence Berkeley National Laboratory