Searching for up to 100 curated homologs for GFF2911 FitnessBrowser__Marino:GFF2911 (256 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
G0HY85 acetoacetyl-CoA reductase (EC 1.1.1.36) from Haloarcula hispanica (see paper)
37% identity, 97% coverage of query (140 bits)
3pk0B / A0QQJ6 Crystal structure of short-chain dehydrogenase/reductase sdr from mycobacterium smegmatis (see paper)
38% identity, 96% coverage of query (140 bits)
PATN_PENEN / A0A075TRB3 Isoepoxydon dehydrogenase patN; IDH; Patulin biosynthesis cluster protein N; EC 1.1.1.- from Penicillium expansum (Blue mold rot fungus) (see 8 papers)
34% identity, 93% coverage of query (132 bits)
3ak4A / G1K3P5 Crystal structure of nadh-dependent quinuclidinone reductase from agrobacterium tumefaciens
38% identity, 95% coverage of query (131 bits)
FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
34% identity, 95% coverage of query (131 bits)
Q5SLC4 aldose 1-dehydrogenase (NAD+) (EC 1.1.1.121) from Thermus thermophilus (see paper)
38% identity, 96% coverage of query (131 bits)
4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
33% identity, 95% coverage of query (130 bits)
2d1yA Crystal structure of tt0321 from thermus thermophilus hb8
38% identity, 96% coverage of query (129 bits)
1vl8B / Q9WYS2 Crystal structure of gluconate 5-dehydrogenase (tm0441) from thermotoga maritima at 2.07 a resolution
36% identity, 95% coverage of query (128 bits)
uxaD / Q9WYS2 fructuronate reductase from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
36% identity, 95% coverage of query (128 bits)
PATN_ASPCL / A1CFM1 Isoepoxydon dehydrogenase patN; IDH; Patulin synthesis protein N; EC 1.1.1.- from Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) (see 3 papers)
33% identity, 95% coverage of query (128 bits)
patN / Q9HGE3 isoepoxydon dehydrogenase from Penicillium urticae (see 5 papers)
34% identity, 93% coverage of query (127 bits)
2zatA / Q8WNV7 Crystal structure of a mammalian reductase (see paper)
34% identity, 94% coverage of query (125 bits)
Q58LW6 D-arabinitol dehydrogenase (NADP+) (EC 1.1.1.287) from Gluconobacter oxydans (see paper)
36% identity, 94% coverage of query (125 bits)
snoaD / CAA12013.1 SnoaD from Streptomyces nogalater (see 3 papers)
34% identity, 95% coverage of query (125 bits)
DHRS4_PIG / Q8WNV7 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NDRD; Peroxisomal carbonyl reductase; PerCR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; Short chain dehydrogenase/reductase family 25C member 2; Protein SDR25C2; EC 1.1.1.184; EC 1.1.1.300 from Sus scrofa (Pig) (see 3 papers)
35% identity, 92% coverage of query (125 bits)
4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
36% identity, 95% coverage of query (125 bits)
DHRS4_RABIT / Q9GKX2 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase; CR; RACR; NADPH-dependent retinol dehydrogenase/reductase; NDRD; Peroxisomal short-chain alcohol dehydrogenase; PSCD; Short chain dehydrogenase/reductase family 25C member 2; Protein SDR25C2; rabNRDR; EC 1.1.1.184; EC 1.1.1.300 from Oryctolagus cuniculus (Rabbit) (see 3 papers)
35% identity, 92% coverage of query (125 bits)
Q86RB1 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Plasmodium falciparum (see paper)
34% identity, 92% coverage of query (124 bits)
1xkqA / Q9N5G4 Crystal structure of short-chain dehydrogenase/reductase of unknown function from caenorhabditis elegans with cofactor
32% identity, 95% coverage of query (124 bits)
fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
31% identity, 95% coverage of query (124 bits)
Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Staphylococcus aureus (see paper)
33% identity, 94% coverage of query (123 bits)
FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
33% identity, 94% coverage of query (123 bits)
dpsE / Q54812 daunorubicin polyketide synthase reductase from Streptomyces peucetius (see paper)
32% identity, 95% coverage of query (122 bits)
6t77A / W9B6I8 Crystal structure of klebsiella pneumoniae fabg(NADPH-dependent) NADP- complex at 1.75 a resolution (see paper)
35% identity, 96% coverage of query (122 bits)
PS417_07245 2-deoxy-D-ribonate 3-dehydrogenase from Pseudomonas simiae WCS417
PS417_07245 / A0A1N7UEI0 2-deoxy-D-ribonate dehydrogenase from Pseudomonas simiae (see paper)
34% identity, 94% coverage of query (122 bits)
6jhbB Crystal structure of NADPH and 4-hydroxyphenylpyruvic acid bound aerf from microcystis aeruginosa (see paper)
30% identity, 92% coverage of query (122 bits)
7v0hG / B4E6Z1 Crystal structure of putative glucose 1-dehydrogenase from burkholderia cenocepacia in complex with NADP and a potential reaction product
35% identity, 97% coverage of query (122 bits)
3o4rA / Q9BTZ2 Crystal structure of human dehydrogenase/reductase (sdr family) member 4 (dhrs4)
34% identity, 92% coverage of query (122 bits)
DHRS4_HUMAN / Q9BTZ2 Dehydrogenase/reductase SDR family member 4; NADPH-dependent carbonyl reductase; CR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; SCAD-SRL; Short chain dehydrogenase/reductase family 25C member 2; Protein SDR25C2; Short-chain dehydrogenase/reductase family member 4; EC 1.1.1.184 from Homo sapiens (Human) (see 7 papers)
Q9BTZ2 NADP-retinol dehydrogenase (EC 1.1.1.300) from Homo sapiens (see paper)
34% identity, 92% coverage of query (121 bits)
3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
35% identity, 97% coverage of query (120 bits)
A1IG83 (R)-aminopropanol dehydrogenase (EC 1.1.1.75) from Rhodococcus erythropolis (see paper)
36% identity, 96% coverage of query (120 bits)
3toxA / Q92SS3 Crystal structure of a short chain dehydrogenase in complex with NAD(p) from sinorhizobium meliloti 1021
36% identity, 94% coverage of query (120 bits)
3sj7A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
33% identity, 94% coverage of query (120 bits)
LOC100862709 / H6AGY1 3-dehydroecdysone-3α-reductase from Bombyx mori (see 2 papers)
32% identity, 96% coverage of query (119 bits)
R4QQK2 tropinone reductase I (EC 1.1.1.206) from Anisodus luridus (see paper)
34% identity, 95% coverage of query (119 bits)
B2L2W8 tropinone reductase I (EC 1.1.1.206) from Anisodus acutangulus (see 3 papers)
34% identity, 95% coverage of query (119 bits)
S5U393 7alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159) from Comamonas testosteroni (see paper)
34% identity, 95% coverage of query (119 bits)
1xhlA / Q19774 Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
31% identity, 95% coverage of query (118 bits)
7xqmB / Q72LQ6 Indel-mutant short chain dehydrogenase bound to sah (see paper)
38% identity, 96% coverage of query (118 bits)
1xhlB Crystal structure of putative tropinone reductase-ii from caenorhabditis elegans with cofactor and substrate
31% identity, 95% coverage of query (118 bits)
HdhA / b1619 7-α-hydroxysteroid dehydrogenase (EC 1.1.1.159) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
hdhA / P0AET8 7-α-hydroxysteroid dehydrogenase (EC 1.1.1.159) from Escherichia coli (strain K12) (see 9 papers)
HDHA_ECOLI / P0AET8 7alpha-hydroxysteroid dehydrogenase; 7alpha-HSDH; NAD-dependent 7alpha-hydroxysteroid dehydrogenase; EC 1.1.1.159 from Escherichia coli (strain K12) (see 3 papers)
1ahiA / P0AET8 7 alpha-hydroxysteroid dehydrogenase complexed with nadh and 7-oxo glycochenodeoxycholic acid (see paper)
hdhA 7-alpha-hydroxysteroid dehydrogenase; EC 1.1.1.159 from Escherichia coli K12 (see 6 papers)
33% identity, 95% coverage of query (117 bits)
A0A6B7HCZ2 tropinone reductase I (EC 1.1.1.206) from Przewalskia tangutica (see paper)
32% identity, 98% coverage of query (117 bits)
aknA / Q9L553 aclacinomycin polyketide synthase reductase from Streptomyces galilaeus (see paper)
33% identity, 93% coverage of query (117 bits)
5itvA / P39640 Crystal structure of bacillus subtilis bacc dihydroanticapsin 7- dehydrogenase in complex with nadh (see paper)
33% identity, 96% coverage of query (117 bits)
A0A2K9VPX3 D-arabinitol 4-dehydrogenase (EC 1.1.1.11) from Gluconobacter sp. JX-05 (see paper)
34% identity, 94% coverage of query (117 bits)
FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
35% identity, 96% coverage of query (117 bits)
1ahhA 7 alpha-hydroxysteroid dehydrogenase complexed with NAD+
33% identity, 95% coverage of query (117 bits)
4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
35% identity, 97% coverage of query (117 bits)
NR_NARAP / A0A1C9II22 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- from Narcissus aff. pseudonarcissus MK-2014 (Daffodil) (see paper)
NR_NARPS / A0A1A9TAK5 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- from Narcissus pseudonarcissus (Daffodil) (see 2 papers)
5ff9B / A0A1A9TAK5 Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and tyramine (see paper)
33% identity, 96% coverage of query (116 bits)
5t5qC / Q2YL80 Crystal structure of short-chain dehydrogenase/reductase sdr:glucose/ribitol dehydrogenase from brucella melitensis
35% identity, 95% coverage of query (116 bits)
6ci9D / A0QP46 Rmm microcompartment-associated aminopropanol dehydrogenase NADP + aminoacetone holo-structure (see paper)
34% identity, 97% coverage of query (116 bits)
bacC / P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (strain 168) (see paper)
BACC_BACSU / P39640 Dihydroanticapsin 7-dehydrogenase; Bacilysin biosynthesis oxidoreductase BacC; EC 1.1.1.385 from Bacillus subtilis (strain 168) (see 3 papers)
P39640 dihydroanticapsin dehydrogenase (EC 1.1.1.385) from Bacillus subtilis (see paper)
33% identity, 95% coverage of query (116 bits)
YLX6_SCHPO / Q9URX0 Uncharacterized oxidoreductase C922.06; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
33% identity, 94% coverage of query (116 bits)
BPHYT_RS16120 sorbitol dehydrogenase, D-fructose forming (EC 1.1.1.14) from Burkholderia phytofirmans PsJN
34% identity, 93% coverage of query (116 bits)
BN592_00769 / R7B6R4 3α-hydroxysteroid dehydrogenase (EC 1.1.1.52) from Eggerthella sp. CAG:298 (see paper)
R7B6R4 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213) from Eggerthella sp. CAG:298 (see paper)
33% identity, 95% coverage of query (116 bits)
DHB14_HUMAN / Q9BPX1 17-beta-hydroxysteroid dehydrogenase 14; 17-beta-HSD 14; 17-beta-hydroxysteroid dehydrogenase DHRS10; Dehydrogenase/reductase SDR family member 10; Retinal short-chain dehydrogenase/reductase retSDR3; Short chain dehydrogenase/reductase family 47C member 1; EC 1.1.1.62 from Homo sapiens (Human) (see 2 papers)
Q9BPX1 17beta-estradiol 17-dehydrogenase (EC 1.1.1.62) from Homo sapiens (see 2 papers)
33% identity, 87% coverage of query (116 bits)
AO356_20240 L-arabinose 1-dehydrogenase (EC 1.1.1.46) from Pseudomonas fluorescens FW300-N2C3
35% identity, 93% coverage of query (116 bits)
6emmA / Q9BPX1 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with salicylic acid
33% identity, 87% coverage of query (116 bits)
5fffA Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and piperonal
33% identity, 96% coverage of query (116 bits)
1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
35% identity, 96% coverage of query (116 bits)
6zt2A 17beta-hydroxysteroid dehydrogenase type 14 variant s205 in complex with 3-chloro-2,6-difluorophenol
33% identity, 86% coverage of query (116 bits)
6zdiA 17beta-hydroxysteroid dehydrogenase type 14 variant s205 in complex with 2-fluoro-5-nitrophenol
33% identity, 86% coverage of query (116 bits)
6zdeA 17beta-hydroxysteroid dehydrogenase type 14 variant s205 in complex with pentafluorophenol
33% identity, 86% coverage of query (116 bits)
6qckA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with fb262
33% identity, 87% coverage of query (116 bits)
5en4A Complex of 17-beta-hydroxysteroid dehydrogenase type 14 with inhibitor.
33% identity, 86% coverage of query (116 bits)
5l7wA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal inhibitor.
33% identity, 87% coverage of query (116 bits)
6gtbA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with fb211
33% identity, 87% coverage of query (116 bits)
5o7cA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
33% identity, 87% coverage of query (116 bits)
5o6zA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
33% identity, 87% coverage of query (116 bits)
5l7yA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal inhibitor.
33% identity, 87% coverage of query (116 bits)
5l7tA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal inhibitor.
33% identity, 87% coverage of query (116 bits)
5hs6A Human 17beta-hydroxysteroid dehydrogenase type 14 in complex with estrone
33% identity, 87% coverage of query (116 bits)
5icmA 17beta-hydroxysteroid dehydrogenase type 14 in complex with a non- steroidal inhibitor
33% identity, 87% coverage of query (116 bits)
5o72A 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
33% identity, 87% coverage of query (116 bits)
5o43A 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal 2,6-pyridinketone inhibitor.
33% identity, 86% coverage of query (116 bits)
5o6oA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal 2,6-pyridinketone inhibitor
33% identity, 86% coverage of query (116 bits)
5o42A 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal 2,6-pyridinketone inhibitor.
33% identity, 86% coverage of query (116 bits)
5o6xA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with a non-steroidal quinoline based inhibitor
33% identity, 86% coverage of query (116 bits)
6gtuA 17beta-hydroxysteroid dehydrogenase 14 variant t205 in complex with fragment j6
33% identity, 87% coverage of query (116 bits)
8hsaA / Q8YIN7 Brucella melitensis 7-alpha-hydroxysteroid dehydrogenase mutant: 1-53 truncation/m196i/i258m/k262t-NAD+
34% identity, 86% coverage of query (115 bits)
swb2 / D2KTX1 3-hydroxykynurenate reductase/dehydratase from Streptomyces sp. SNA15896 (see paper)
34% identity, 95% coverage of query (115 bits)
AFO85456.1 reductase/oxidase from Marinactinospora thermotolerans (see paper)
33% identity, 94% coverage of query (115 bits)
Q5FNX9 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Gluconobacter oxydans (see paper)
34% identity, 94% coverage of query (115 bits)
1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
35% identity, 96% coverage of query (115 bits)
6jhaA Crystal structure of NADPH bound aerf from microcystis aeruginosa (see paper)
30% identity, 92% coverage of query (114 bits)
Pf6N2E2_5967 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Pseudomonas fluorescens FW300-N2E2
34% identity, 93% coverage of query (114 bits)
GOLD_LISIN / Q92EU6 NAD-dependent glycerol dehydrogenase; Dha-forming NAD-dependent glycerol dehydrogenase; EC 1.1.1.6 from Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262) (see paper)
33% identity, 96% coverage of query (114 bits)
FABG_SALTY / P0A2C9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
34% identity, 96% coverage of query (113 bits)
Build an alignment for GFF2911 and 89 homologs with ≥ 30% identity
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3ijrF / A0A6L8PL20 2.05 angstrom resolution crystal structure of a short chain dehydrogenase from bacillus anthracis str. 'Ames ancestor' in complex with NAD+
28% identity, 96% coverage of query (113 bits)
TR1 / P50162 tropinone reductase (EC 1.1.1.206) from Datura stramonium (see paper)
TRN1_DATST / P50162 Tropinone reductase 1; Tropine dehydrogenase; Tropinone reductase I; TR-I; EC 1.1.1.206 from Datura stramonium (Jimsonweed) (Common thornapple) (see 2 papers)
P50162 tropinone reductase I (EC 1.1.1.206) from Datura stramonium (see 2 papers)
33% identity, 95% coverage of query (113 bits)
Q308C1 D-arabinitol 4-dehydrogenase (EC 1.1.1.11); D-arabinitol dehydrogenase (NADP+) (EC 1.1.1.287) from Gluconobacter oxydans (see paper)
33% identity, 94% coverage of query (113 bits)
ARC78_08055 / A0A0R0ADD3 7α-hydroxysteroid dehydrogenase (EC 1.1.1.159) from Stenotrophomonas pictorum JCM 9942 (see paper)
32% identity, 99% coverage of query (113 bits)
1ae1B / P50162 Tropinone reductase-i complex with NADP (see paper)
33% identity, 95% coverage of query (113 bits)
GMDH_GLUOX / Q5FPE5 Glucose 1-dehydrogenase; EC 1.1.1.119 from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see paper)
33% identity, 95% coverage of query (113 bits)
6pejA / Q92N06 Structure of sorbitol dehydrogenase from sinorhizobium meliloti 1021 bound to sorbitol
33% identity, 97% coverage of query (113 bits)
U5PUZ1 tropinone reductase I (EC 1.1.1.206) from Withania somnifera (see paper)
33% identity, 95% coverage of query (113 bits)
tpdE / M1WXK8 aminoalcohol dehydrogenase from Rhodococcus sp. TMP1 (see paper)
tpdE / CCN27364.1 aminoalcohol dehydrogenase from Rhodococcus sp. TMP1 (see paper)
29% identity, 96% coverage of query (113 bits)
A3GF07 carbonyl reductase (NADPH) (EC 1.1.1.184) from Scheffersomyces stipitis (see 2 papers)
31% identity, 95% coverage of query (113 bits)
H281DRAFT_00644 2-deoxy-D-ribonate 3-dehydrogenase from Paraburkholderia bryophila 376MFSha3.1
35% identity, 93% coverage of query (113 bits)
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