Searching for up to 100 curated homologs for GFF2963 FitnessBrowser__WCS417:GFF2963 (371 a.a.)
Found high-coverage hits (≥70%) to 71 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
K7ZP76 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Paracoccus laeviglucosivorans (see paper)
lgdA / BAM68195.1 scyllo-inositol dehydrogenase with L-glucose dehydrogenase activity from Paracoccus laeviglucosivorans (see 2 papers)
47% identity, 95% coverage of query (282 bits)
5yaqB Crystal structure of scyllo-inositol dehydrogenase with l-glucose dehydrogenase activity complexed with scyllo-inosose
47% identity, 94% coverage of query (279 bits)
5ya8A Crystal structure of scyllo-inositol dehydrogenase with l-glucose dehydrogenase activity complexed with myo-inositol
47% identity, 94% coverage of query (279 bits)
6ktkC / K7ZP76 Crystal structure of scyllo-inositol dehydrogenase r178a mutant, complexed with nadh and l-glucono-1,5-lactone, from paracoccus laeviglucosivorans (see paper)
46% identity, 95% coverage of query (277 bits)
6a3jC / F0M433 Levoglucosan dehydrogenase, complex with nadh and l-sorbose (see paper)
40% identity, 98% coverage of query (263 bits)
Asphe3_10730 / F0M433 levoglucosan dehydrogenase monomer (EC 1.1.1.425) from Pseudarthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3) (see 2 papers)
LGDH_PSEPM / F0M433 Levoglucosan dehydrogenase; LGDH; 1,6-anhydro-beta-D-glucose dehydrogenase; PpLGDH; EC 1.1.1.425 from Pseudarthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3) (Arthrobacter phenanthrenivorans) (see paper)
F0M433 levoglucosan dehydrogenase (EC 1.1.1.425) from Pseudarthrobacter phenanthrenivorans (see paper)
39% identity, 99% coverage of query (261 bits)
6a3iA Levoglucosan dehydrogenase, complex with nadh and levoglucosan
40% identity, 99% coverage of query (259 bits)
Q5KYQ3 inositol 2-dehydrogenase (EC 1.1.1.18) from Geobacillus kaustophilus (see paper)
33% identity, 100% coverage of query (204 bits)
Echvi_3375 predicted 3-ketohexose reductase from Echinicola vietnamensis KMM 6221, DSM 17526
33% identity, 92% coverage of query (184 bits)
Build an alignment for GFF2963 and 9 homologs with ≥ 30% identity
Or download the sequences
Echvi_1844 predicted 3-ketohexose reductase from Echinicola vietnamensis KMM 6221, DSM 17526
28% identity, 86% coverage of query (124 bits)
CCNA_01702 predicted 3-ketohexose reductase from Caulobacter crescentus NA1000
30% identity, 90% coverage of query (122 bits)
6jw7A / Q6L737 The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin a (see paper)
33% identity, 73% coverage of query (120 bits)
6jw6A The crystal structure of kand2 in complex with NAD
33% identity, 73% coverage of query (120 bits)
6jw8A The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin b
33% identity, 73% coverage of query (120 bits)
CA265_RS15350 predicted 3-ketohexose reductase from Pedobacter sp. GW460-11-11-14-LB5
28% identity, 77% coverage of query (114 bits)
iolX / P40332 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Bacillus subtilis (strain 168) (see paper)
IOLX_BACSU / P40332 scyllo-inositol 2-dehydrogenase (NAD(+)); EC 1.1.1.370 from Bacillus subtilis (strain 168) (see paper)
P40332 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Bacillus subtilis (see 2 papers)
30% identity, 72% coverage of query (107 bits)
1evjA Crystal structure of glucose-fructose oxidoreductase (gfor) delta1-22 s64d
29% identity, 74% coverage of query (103 bits)
SM_b20330 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) from Sinorhizobium meliloti 1021
29% identity, 72% coverage of query (100 bits)
gfo / Q07982 glucose-fructose oxidoreductase (EC 1.1.99.28) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) (see paper)
Q07982 glucose-fructose oxidoreductase (EC 1.1.99.28) from Zymomonas mobilis (see 4 papers)
26% identity, 99% coverage of query (100 bits)
1h6dA / Q07982 Oxidized precursor form of glucose-fructose oxidoreductase from zymomonas mobilis complexed with glycerol (see paper)
26% identity, 99% coverage of query (100 bits)
1rydA Crystal structure of glucose-fructose oxidoreductase from zymomonas mobilis
26% identity, 99% coverage of query (100 bits)
iolG / Q9WYP5 myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
IOLG_THEMA / Q9WYP5 Myo-inositol 2-dehydrogenase; EC 1.1.1.18 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9WYP5 D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Thermotoga maritima (see paper)
27% identity, 74% coverage of query (99.4 bits)
5a05A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with maltotriose
27% identity, 83% coverage of query (96.7 bits)
5a04A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glucose
27% identity, 83% coverage of query (96.7 bits)
5a03E Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose
27% identity, 83% coverage of query (96.7 bits)
5a02A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glycerol
27% identity, 83% coverage of query (96.7 bits)
5a03C / Q9A8X3 Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose (see paper)
27% identity, 83% coverage of query (96.3 bits)
APSD_PARG4 / B1G894 D-apiose dehydrogenase; EC 1.1.1.420 from Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) (see paper)
28% identity, 79% coverage of query (96.3 bits)
YM94_YEAST / Q04869 Uncharacterized protein YMR315W from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
27% identity, 73% coverage of query (96.3 bits)
5a06A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with sorbitol
27% identity, 83% coverage of query (96.3 bits)
1zh8A / Q9WYE8 Crystal structure of oxidoreductase (tm0312) from thermotoga maritima at 2.50 a resolution
24% identity, 80% coverage of query (95.5 bits)
apsD / B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium radiobacter (strain K84 / ATCC BAA-868) (see paper)
APSD_RHIR8 / B9JK80 D-apiose dehydrogenase; EC 1.1.1.420 from Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter) (see paper)
B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium tumefaciens (see paper)
30% identity, 83% coverage of query (94.4 bits)
5uhwA / B9JK80 Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+ and magnesium
30% identity, 82% coverage of query (92.8 bits)
5uiaA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, r-2,3-dihydroxyisovalerate and magnesium
30% identity, 82% coverage of query (92.8 bits)
5ui9A Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, 2 -hydroxy-2-hydroxymethyl propanoic acid and magnesium
30% identity, 82% coverage of query (92.8 bits)
5uhzA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, d-apionate and magnesium
30% identity, 82% coverage of query (92.8 bits)
ntdC / O07564 glucose-6-phosphate 3-dehydrogenase (EC 1.1.1.361) from Bacillus subtilis (strain 168) (see 4 papers)
NTDC_BACSU / O07564 Glucose-6-phosphate 3-dehydrogenase; EC 1.1.1.361 from Bacillus subtilis (strain 168) (see 3 papers)
O07564 glucose-6-phosphate 3-dehydrogenase (EC 1.1.1.361) from Bacillus subtilis (see 2 papers)
27% identity, 70% coverage of query (92.4 bits)
D4GR07 L-arabinose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.376) from Haloferax volcanii (see paper)
28% identity, 80% coverage of query (85.5 bits)
3q2kK / Q79H45 Crystal structure of the wlba dehydrogenase from bordetella pertussis in complex with nadh and udp-glcnaca (see paper)
28% identity, 82% coverage of query (84.7 bits)
cbaC / Q44258 3-chlorobenzoate-cis-diol hydrogenase from Comamonas testosteroni (see paper)
cbaC / AAC45718.1 1-carboxy-3-chloro-3,4-dihydroxycyclohexa-1, 5-diene dehydrogenase from Conidiobolus coronatus (see 4 papers)
28% identity, 71% coverage of query (83.6 bits)
3q2kC / Q79H45 Crystal structure of the wlba dehydrogenase from bordetella pertussis in complex with nadh and udp-glcnaca (see paper)
28% identity, 73% coverage of query (83.6 bits)
DHDH_MACFU / Q7JK39 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; Jmo2DD; EC 1.3.1.20; EC 1.1.1.179 from Macaca fuscata fuscata (Japanese macaque) (see 3 papers)
DHDH_MACFA / Q9TQS6 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Cmo2DD; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; EC 1.3.1.20; EC 1.1.1.179 from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
Q9TQS6 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Macaca fascicularis (see 2 papers)
27% identity, 72% coverage of query (82.0 bits)
2o4uX / Q9TQS6 Crystal structure of mammalian dimeric dihydrodiol dehydrogenase (see paper)
27% identity, 72% coverage of query (82.0 bits)
2poqX Dimeric dihydrodiol dehydrogenase complexed with inhibitor, isoascorbic acid
27% identity, 72% coverage of query (82.0 bits)
UGNO_METMP / Q6M0B9 UDP-N-acetylglucosamine 3-dehydrogenase; UDP-GlcNAc oxidoreductase; UDP-N-acetyl-alpha-D-glucosamine:NAD(+) 3-oxidoreductase; EC 1.1.1.374 from Methanococcus maripaludis (strain S2 / LL) (see paper)
Q6M0B9 UDP-N-acetylglucosamine 3-dehydrogenase (EC 1.1.1.374) from Methanococcus maripaludis (see paper)
24% identity, 74% coverage of query (79.7 bits)
SM_b20899 Inositol 2-dehydrogenase (EC 1.1.1.18) from Sinorhizobium meliloti 1021
MI2D_RHIME / O68965 Inositol 2-dehydrogenase; Myo-inositol 2-dehydrogenase; MI-dehydrogenase; EC 1.1.1.18 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
O68965 inositol 2-dehydrogenase (EC 1.1.1.18) from Sinorhizobium meliloti (see paper)
28% identity, 71% coverage of query (79.3 bits)
HSERO_RS12095 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Herbaspirillum seropedicae SmR1
27% identity, 78% coverage of query (78.2 bits)
Q5R5J5 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Pongo abelii (see paper)
26% identity, 72% coverage of query (78.2 bits)
3ceaA / F9ULF9 Crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from lactobacillus plantarum at 2.40 a resolution
24% identity, 73% coverage of query (77.8 bits)
6o15A / P39353 Crystal structure of a putative oxidoreductase yjhc from escherichia coli in complex with NAD(h) (see paper)
26% identity, 76% coverage of query (76.3 bits)
PS417_11875 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas simiae WCS417
28% identity, 72% coverage of query (75.9 bits)
3e18A / Q929L3 Crystal structure of NAD-binding protein from listeria innocua
26% identity, 73% coverage of query (75.9 bits)
NanY / b4280 KpLE2 phage-like element; 2,7-anhydro-N-acetylneuraminate hydratase from Escherichia coli K-12 substr. MG1655 (see 4 papers)
nanY / P39353 KpLE2 phage-like element; 2,7-anhydro-N-acetylneuraminate hydratase from Escherichia coli (strain K12) (see 6 papers)
NANY_ECOLI / P39353 2,7-anhydro-N-acetylneuraminate hydratase; EcNanOx; EC 4.2.1.- from Escherichia coli (strain K12) (see 4 papers)
26% identity, 76% coverage of query (75.9 bits)
P72782 biliverdin reductase (EC 1.3.1.24) from Synechocystis sp. PCC 6803 (see paper)
28% identity, 73% coverage of query (74.3 bits)
5b3uB / P72782 Crystal structure of biliverdin reductase in complex with NADP+ from synechocystis sp. Pcc 6803 (see paper)
28% identity, 73% coverage of query (74.3 bits)
5b3vA Crystal structure of biliverdin reductase in complex with biliverdin and NADP+ from synechocystis sp. Pcc 6803
28% identity, 73% coverage of query (74.3 bits)
DHDH_HUMAN / Q9UQ10 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; Hum2DD; EC 1.3.1.20; EC 1.1.1.179 from Homo sapiens (Human) (see paper)
25% identity, 73% coverage of query (73.9 bits)
AO353_21365 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas fluorescens FW300-N2E3
28% identity, 72% coverage of query (73.2 bits)
4n54A / A0A0J9X1Y7 Crystal structure of scyllo-inositol dehydrogenase from lactobacillus casei with bound cofactor NAD(h) and scyllo-inositol
24% identity, 83% coverage of query (73.2 bits)
AO356_23190 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas fluorescens FW300-N2C3
28% identity, 72% coverage of query (72.0 bits)
E1U888 inositol 2-dehydrogenase (EC 1.1.1.18) from Lacticaseibacillus casei (see paper)
24% identity, 83% coverage of query (70.5 bits)
3rc1A / B3TMR8 Crystal structure of kijd10, a 3-ketoreductase from actinomadura kijaniata incomplex with NADP and tdp-benzene (see paper)
27% identity, 71% coverage of query (68.2 bits)
KIJDR_ACTKI / B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; 3-ketoreductase; NADPH-dependent C3-ketoreductase; EC 1.1.1.384 from Actinomadura kijaniata (see paper)
B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Actinomadura kijaniata (see paper)
27% identity, 71% coverage of query (68.2 bits)
NANY_RUMGV / A7B558 2,7-anhydro-N-acetylneuraminate hydratase; RgNanOx; EC 4.2.1.- from Ruminococcus gnavus (strain ATCC 29149 / VPI C7-9) (see 2 papers)
22% identity, 87% coverage of query (66.6 bits)
3q2iA / Q7NQL0 Crystal structure of the wlba dehydrognase from chromobactrium violaceum in complex with nadh and udp-glcnaca at 1.50 a resolution (see paper)
24% identity, 76% coverage of query (66.6 bits)
6z3cAAA / A0A2N5NNS3 6z3cAAA (see paper)
22% identity, 87% coverage of query (66.6 bits)
Q7NQL0 UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase (EC 1.1.1.335) from Chromobacterium violaceum (see paper)
24% identity, 76% coverage of query (66.2 bits)
8qc8D Crystal structure of NAD-dependent glycoside hydrolase from flavobacterium sp. (Strain k172) in complex with co-factor NAD+ (see paper)
24% identity, 71% coverage of query (60.8 bits)
8qc2A Crystal structure of NAD-dependent glycoside hydrolase from flavobacterium sp. (Strain k172) in complex with co-factor NAD+ and sulfoquinovose (sq)
24% identity, 71% coverage of query (58.9 bits)
8qc8B Crystal structure of NAD-dependent glycoside hydrolase from flavobacterium sp. (Strain k172) in complex with co-factor NAD+ (see paper)
24% identity, 71% coverage of query (58.9 bits)
8qc6A / A0A1C9WRL0 Crystal structure of NAD-dependent glycoside hydrolase from arthrobacter sp. U41 in complex with NAD+ and sulfoquinovose (sq) (see paper)
23% identity, 72% coverage of query (53.1 bits)
Or start over
Lawrence Berkeley National Laboratory