Searching for up to 100 curated homologs for GFF2997 FitnessBrowser__WCS417:GFF2997 (273 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YeaE / b1781 methylglyoxal reductase YeaE from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yeaE / P76234 methylglyoxal reductase YeaE (EC 1.1.1.21) from Escherichia coli (strain K12) (see 3 papers)
56% identity, 100% coverage of query (311 bits)
4wghA Crystal structure of aldo/keto reductase from klebsiella pneumoniae in complex with NADP and acetate at 1.8 a resolution
58% identity, 96% coverage of query (306 bits)
6ciaA / A6T7Q7 Crystal structure of aldo-keto reductase from klebsiella pneumoniae in complex with NADPH.
58% identity, 96% coverage of query (305 bits)
5c7hA / Q92NR7 Crystal structure of aldo-keto reductase from sinorhizobium meliloti 1021 in complex with NADPH
56% identity, 97% coverage of query (289 bits)
4pmjA Crystal structure of a putative oxidoreductase from sinorhizobium meliloti 1021 in complex with NADP
56% identity, 97% coverage of query (289 bits)
6kikA / Q9X265 Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor tolrestat (see paper)
42% identity, 93% coverage of query (173 bits)
Q9X265 carbonyl reductase (NADPH) (EC 1.1.1.184) from Thermotoga maritima (see 2 papers)
42% identity, 93% coverage of query (173 bits)
6kiyA Crystal structure of a thermostable aldo-keto reductase tm1743 in complex with inhibitor epalrestat
42% identity, 93% coverage of query (173 bits)
5danA Crystal structure of a novel aldo keto reductase tm1743 from thermotoga maritima in complex with NADP+
42% identity, 93% coverage of query (173 bits)
Q8TZM9 alcohol dehydrogenase (EC 1.1.1.1) from Pyrococcus furiosus (see 2 papers)
40% identity, 92% coverage of query (152 bits)
Q5JI09 alcohol dehydrogenase (EC 1.1.1.1) from Thermococcus kodakarensis (see paper)
39% identity, 90% coverage of query (141 bits)
F2YCN5 D-xylose reductase (EC 1.1.1.307) from Zymomonas mobilis subsp. mobilis (see paper)
31% identity, 90% coverage of query (125 bits)
Q4DJ07 prostaglandin-F synthase (EC 1.1.1.188) from Trypanosoma cruzi (see paper)
32% identity, 96% coverage of query (121 bits)
4gieA / Q4DJ07 Crystal structure of prostaglandin f synthase from trypanosoma cruzi bound to NADP (see paper)
32% identity, 92% coverage of query (120 bits)
4fziA Crystal structure of prostaglandin f synthase from trypanosoma cruzi
32% identity, 92% coverage of query (120 bits)
A0QV10 Aldo-keto reductase MSMEG_2408/MSMEI_2347; EC 1.1.1.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
35% identity, 92% coverage of query (119 bits)
1vbjA / Q9GV41 The crystal structure of prostaglandin f synthase from trypanosoma brucei
32% identity, 92% coverage of query (114 bits)
PGFS_TRYBB / Q9GV41 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Trypanosoma brucei brucei (see paper)
32% identity, 92% coverage of query (114 bits)
GCY1 putative uncharacterized protein from Candida albicans (see paper)
31% identity, 93% coverage of query (114 bits)
akr5f1 organophosphate reductase from Klebsiella sp. F51-1-2 (see paper)
31% identity, 94% coverage of query (110 bits)
4g5dA / P22045 X-ray crystal structure of prostaglandin f synthase from leishmania major friedlin bound to NADPH (see paper)
33% identity, 92% coverage of query (110 bits)
PGFS_LEIMA / P22045 9,11-endoperoxide prostaglandin H2 reductase; Prostaglandin F2-alpha synthase; EC 1.1.1.- from Leishmania major (see paper)
P22045 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania major (see paper)
33% identity, 92% coverage of query (110 bits)
Build an alignment for GFF2997 and 22 homologs with ≥ 30% identity
Or download the sequences
DkgB / b0207 methylglyoxal reductase DkgB (EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
dkgB / P30863 methylglyoxal reductase DkgB (EC 1.1.1.21; EC 1.1.1.91; EC 1.1.1.346) from Escherichia coli (strain K12) (see 5 papers)
dkgB / MB|P30863 2,5-diketo-D-gluconic acid reductase B; EC 1.1.1.274 from Escherichia coli K12 (see 5 papers)
29% identity, 90% coverage of query (107 bits)
yvgN / O32210 glyoxal/methylglyoxal reductase (EC 1.1.1.283; EC 1.1.1.91) from Bacillus subtilis (strain 168) (see 3 papers)
GR_BACSU / O32210 Glyoxal reductase; GR; Methylglyoxal reductase; EC 1.1.1.-; EC 1.1.1.283 from Bacillus subtilis (strain 168) (see paper)
36% identity, 92% coverage of query (107 bits)
3d3fA / O32210 Crystal structure of yvgn and cofactor NADPH from bacillus subtilis (see paper)
36% identity, 92% coverage of query (107 bits)
IOLS_BACSU / P46336 Aldo-keto reductase IolS; AKR11A; Vegetative protein 147; VEG147; EC 1.1.1.- from Bacillus subtilis (strain 168) (see 4 papers)
28% identity, 82% coverage of query (107 bits)
1pz0A / P46336 Structure of NADPH-dependent family 11 aldo-keto reductase akr11a(holo) (see paper)
28% identity, 82% coverage of query (107 bits)
GCY1_YEAST / P14065 Glycerol 2-dehydrogenase (NADP(+)); Galactose-inducible crystallin-like protein 1; EC 1.1.1.156 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 13 papers)
29% identity, 93% coverage of query (107 bits)
3wbwA / Q5FT75 Crystal structure of gox0644 in complex with NADPH
31% identity, 93% coverage of query (106 bits)
Q5FT75 carbonyl reductase (NADPH) (EC 1.1.1.184) from Gluconobacter oxydans (see paper)
31% identity, 93% coverage of query (106 bits)
Y2971_MYCTU / P9WQA5 Aldo-keto reductase Rv2971; AKR; EC 1.1.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
34% identity, 95% coverage of query (106 bits)
3v0sA / Q3L181 Crystal structure of perakine reductase, founder member of a novel akr subfamily with unique conformational changes during NADPH binding (see paper)
30% identity, 92% coverage of query (105 bits)
Y2996_MYCBO / Q7TXI6 Aldo-keto reductase BQ2027_MB2996; EC 1.1.1.- from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
34% identity, 95% coverage of query (105 bits)
YdjG / b1771 NADH-dependent methylglyoxal reductase from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ydjG / P77256 NADH-dependent methylglyoxal reductase from Escherichia coli (strain K12) (see 4 papers)
AKRMG_ECOLI / P77256 NADH-specific methylglyoxal reductase; AKR11B2; EC 1.1.1.- from Escherichia coli (strain K12) (see 3 papers)
ydjG / RF|NP_416285 uncharacterized oxidoreductase ydjG from Escherichia coli K12 (see paper)
29% identity, 93% coverage of query (103 bits)
E3W861 carbonyl reductase (NADPH) (EC 1.1.1.184) from Bacillus sp. (in: Bacteria) (see paper)
3b3dA / O34678 B.Subtilis ytbe (see paper)
34% identity, 92% coverage of query (103 bits)
A0A3P3ZE14 prostaglandin-F synthase (EC 1.1.1.188) from Leishmania braziliensis (see paper)
31% identity, 92% coverage of query (103 bits)
Q5DD64 aldose reductase (EC 1.1.1.21) from Schistosoma japonicum (see paper)
29% identity, 92% coverage of query (102 bits)
DkgA / b3012 methylglyoxal reductase DkgA (EC 1.1.1.346) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
dkgA / Q46857 methylglyoxal reductase DkgA (EC 1.1.1.21; EC 1.1.1.346) from Escherichia coli (strain K12) (see 9 papers)
Q46857 2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming) (EC 1.1.1.346) from Escherichia coli (see paper)
31% identity, 93% coverage of query (102 bits)
GRE3 putative uncharacterized protein GRE3 from Candida albicans (see paper)
30% identity, 95% coverage of query (100 bits)
AK1C1_MACFU / Q95JH6 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fuscata fuscata (Japanese macaque) (see paper)
29% identity, 91% coverage of query (99.4 bits)
AK1C1_MACFA / Q95JH7 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Dihydrodiol dehydrogenase 1; DD-1; DD1; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
29% identity, 91% coverage of query (98.2 bits)
YPR1_YEAST / Q12458 Putative reductase 1; EC 1.1.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
29% identity, 93% coverage of query (97.8 bits)
5az1A Crystal structure of aldo-keto reductase (akr2e5) complexed with nadph (see paper)
28% identity, 96% coverage of query (97.4 bits)
P87039 D-xylose reductase (EC 1.1.1.307) from Candida tropicalis (see paper)
C1K8Y9 D-xylose reductase (EC 1.1.1.307) from Candida tropicalis (see paper)
30% identity, 95% coverage of query (97.4 bits)
YBN4_SCHPO / O42888 Uncharacterized oxidoreductase C8E4.04; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
29% identity, 93% coverage of query (97.1 bits)
A0MTG4 D-xylose reductase (EC 1.1.1.307) from Scheffersomyces shehatae (see paper)
30% identity, 93% coverage of query (97.1 bits)
PR / Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 2 papers)
PERR_RAUSE / Q3L181 Perakine reductase; EC 1.1.1.317 from Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum) (see 2 papers)
Q3L181 perakine reductase (EC 1.1.1.317) from Rauvolfia serpentina (see 3 papers)
29% identity, 92% coverage of query (97.1 bits)
D0VDT4 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149) from Bos taurus (see paper)
30% identity, 91% coverage of query (96.7 bits)
AK1A1_RAT / P51635 Aldo-keto reductase family 1 member A1; 3-DG-reducing enzyme; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Rattus norvegicus (Rat) (see 4 papers)
P51635 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Rattus norvegicus (see 2 papers)
28% identity, 92% coverage of query (96.7 bits)
eryBII / A4F7P4 dTDP-(2R,6S)-6-hydroxy-2-methyl-3-oxo-3,6-dihydro-2H-pyran-4-olate 3-ketoreductase (dTDP-4-dehydro-2,6-dideoxy-α-D-allose-forming) from Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338) (see 2 papers)
30% identity, 81% coverage of query (96.3 bits)
3gugA Crystal structure of akr1c1 l308v mutant in complex with NADP and 3,5- dichlorosalicylic acid
29% identity, 91% coverage of query (96.3 bits)
AKR1_SOYBN / C6TBN2 Probable aldo-keto reductase 1; GmAKR1; EC 1.1.1.- from Glycine max (Soybean) (Glycine hispida) (see paper)
27% identity, 86% coverage of query (95.9 bits)
M6PR / P92923 mannose 6-phosphate reductase (EC 1.1.1.224) from Apium graveolens (see paper)
P92923 mannose-6-phosphate 6-reductase (EC 1.1.1.224) from Apium graveolens (see paper)
28% identity, 92% coverage of query (95.9 bits)
AKR1C1 / Q04828 aldo-keto reductase family 1 member C1 (EC 1.1.1.149; EC 1.1.1.213; EC 1.1.1.112; EC 1.3.1.20) from Homo sapiens (see 13 papers)
AK1C1_HUMAN / Q04828 Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Chlordecone reductase homolog HAKRC; Dihydrodiol dehydrogenase 1; DD1; High-affinity hepatic bile acid-binding protein; HBAB; EC 1.1.1.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.357; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.149 from Homo sapiens (Human) (see 8 papers)
Q04828 20alpha-hydroxysteroid dehydrogenase (EC 1.1.1.149); 3beta-hydroxysteroid 3-dehydrogenase (EC 1.1.1.270); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 13 papers)
29% identity, 91% coverage of query (95.9 bits)
3debr / Q9Y020 3-dehydroecdysone 3β-reductase from Spodoptera littoralis (see 3 papers)
27% identity, 95% coverage of query (95.9 bits)
ALRA_DICDI / Q6IMN8 Aldose reductase A; ARA; Aldehyde reductase A; AlrA; EC 1.1.1.21 from Dictyostelium discoideum (Social amoeba) (see paper)
Q6IMN8 methylglyoxal reductase (NADPH) (EC 1.1.1.283) from Dictyostelium discoideum (see paper)
29% identity, 93% coverage of query (95.9 bits)
3c3uA Crystal structure of akr1c1 in complex with NADP and 3,5- dichlorosalicylic acid
29% identity, 91% coverage of query (95.9 bits)
6ijxA Crystal structure of akr1c1 complexed with meclofenamic acid
29% identity, 91% coverage of query (95.9 bits)
6a7aA Akr1c1 complexed with new inhibitor with novel scaffold
29% identity, 91% coverage of query (95.9 bits)
4yvpA Crystal structure of akr1c1 complexed with glibenclamide
29% identity, 91% coverage of query (95.9 bits)
3ntyA Crystal structure of akr1c1 in complex with NADP and 5-phenyl,3- chlorosalicylic acid
29% identity, 91% coverage of query (95.9 bits)
4jtrB Akr1c2 complex with ibuprofen
29% identity, 91% coverage of query (95.5 bits)
4l1wA / P52895 Crystal structuer of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+ and progesterone (see paper)
29% identity, 91% coverage of query (95.1 bits)
AKR1C2 / P52895 3α hydroxysteroid dehydrogenase III (EC 1.1.1.52; EC 1.1.1.395; EC 1.1.1.213; EC 1.1.1.357) from Homo sapiens (see 12 papers)
AK1C2_HUMAN / P52895 Aldo-keto reductase family 1 member C2; 3-alpha-HSD3; Chlordecone reductase homolog HAKRD; Dihydrodiol dehydrogenase 2; DD-2; DD2; Dihydrodiol dehydrogenase/bile acid-binding protein; DD/BABP; Type III 3-alpha-hydroxysteroid dehydrogenase; EC 1.-.-.-; EC 1.1.1.112; EC 1.1.1.209; EC 1.1.1.53; EC 1.1.1.62; EC 1.3.1.20; EC 1.1.1.357 from Homo sapiens (Human) (see 9 papers)
P52895 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) (EC 1.1.1.213); 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Homo sapiens (see 9 papers)
29% identity, 91% coverage of query (95.1 bits)
1ihiA Crystal structure of human type iii 3-alpha-hydroxysteroid dehydrogenase/bile acid binding protein (akr1c2) complexed with NADP+ and ursodeoxycholate
29% identity, 91% coverage of query (95.1 bits)
4jtrA Akr1c2 complex with ibuprofen
29% identity, 91% coverage of query (95.1 bits)
4jtqA Akr1c2 complex with flurbiprofen
29% identity, 91% coverage of query (95.1 bits)
4jqaA Akr1c2 complex with mefenamic acid
29% identity, 91% coverage of query (95.1 bits)
4jq4A Akr1c2 complex with indomethacin
29% identity, 91% coverage of query (95.1 bits)
4jq3A Akr1c2 complex with zomepirac
29% identity, 91% coverage of query (95.1 bits)
4jq2A Akr1c2 complex with sulindac
29% identity, 91% coverage of query (95.1 bits)
4jq1A Akr1c2 complex with naproxen
29% identity, 91% coverage of query (95.1 bits)
4xo7A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
29% identity, 91% coverage of query (95.1 bits)
2hdjA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h)
29% identity, 91% coverage of query (95.1 bits)
4xo6B Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
29% identity, 91% coverage of query (95.1 bits)
4xo6A Crystal structure of human 3-alpha hydroxysteroid dehydrogenase type 3 in complex with NADP+, 5alpha-androstan-3,17-dione and (3beta, 5alpha)-3-hydroxyandrostan-17-one
29% identity, 91% coverage of query (95.1 bits)
1xjbA Crystal structure of human type 3 3alpha-hydroxysteroid dehydrogenase in complex with NADP(h), citrate and acetate molecules
29% identity, 91% coverage of query (95.1 bits)
1j96A Human 3alpha-hsd type 3 in ternary complex with NADP and testosterone
29% identity, 91% coverage of query (95.1 bits)
DHB5_MOUSE / P70694 Estradiol 17 beta-dehydrogenase 5; 17-beta-HSD 5; EC 1.1.1.- from Mus musculus (Mouse) (see paper)
28% identity, 95% coverage of query (94.7 bits)
3ufyA Akr1c3 complex with r-naproxen
30% identity, 91% coverage of query (94.7 bits)
3r94A Akr1c3 complex with flurbiprofen
30% identity, 91% coverage of query (94.7 bits)
3r8hA Akr1c3 complex with zomepirac
30% identity, 91% coverage of query (94.7 bits)
3r8gA Akr1c3 complex with ibuprofen
30% identity, 91% coverage of query (94.7 bits)
3r7mA Akr1c3 complex with sulindac
30% identity, 91% coverage of query (94.7 bits)
3r6iA Akr1c3 complex with meclofenamic acid
30% identity, 91% coverage of query (94.7 bits)
3r58A Akr1c3 complex with naproxen
30% identity, 91% coverage of query (94.7 bits)
4falA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with 3-((3,4-dihydroisoquinolin-2(1h)-yl)sulfonyl)-n- methylbenzamide (80)
30% identity, 91% coverage of query (94.7 bits)
7x3oA Crystal structure of aldo-keto reductase 1c3 complexed with compound s07054
30% identity, 91% coverage of query (94.7 bits)
A9QVV8 D-xylose reductase (EC 1.1.1.307) from Candida tropicalis (see paper)
30% identity, 95% coverage of query (94.4 bits)
AKR1E2 / P82125 1,5-anhydro-D-fructose reductase (EC 1.1.1.263) from Sus scrofa (see paper)
AKCL2_PIG / P82125 1,5-anhydro-D-fructose reductase; AF reductase; Aldo-keto reductase family 1 member C-like protein 2; Aldo-keto reductase family 1 member CL2; Aldo-keto reductase family 1 member E2; EC 1.1.1.263 from Sus scrofa (Pig) (see paper)
30% identity, 89% coverage of query (94.4 bits)
AK1CL_MOUSE / Q91WR5 Aldo-keto reductase family 1 member C21; 17-alpha-hydroxysteroid dehydrogenase; 17-alpha-HSD; 3(or 17)-alpha-hydroxysteroid dehydrogenase; 3-alpha-hydroxysteroid dehydrogenase; Dihydrodiol dehydrogenase type 1; DD1; Dihydrodiol dehydrogenase type 3; DD3; EC 1.1.1.-; EC 1.1.1.209 from Mus musculus (Mouse) (see 7 papers)
Q91WR5 estradiol 17alpha-dehydrogenase (EC 1.1.1.148); 3(or 17)alpha-hydroxysteroid dehydrogenase (EC 1.1.1.209); 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) (EC 1.1.1.50) from Mus musculus (see 5 papers)
29% identity, 92% coverage of query (94.4 bits)
7bc1A / A9CEY6 Crystal structure of aldo-keto reductase from agrobacterium tumefaciens in a ternary complex with NADPH and glucose (see paper)
30% identity, 86% coverage of query (94.4 bits)
4hmnA Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (4-(4-chlorophenyl)piperazin-1-yl)(morpholino) methanone (24)
30% identity, 91% coverage of query (94.4 bits)
2ipfA Crystal structure of 17alpha-hydroxysteroid dehydrogenase in complex with NADP+ and epi-testosterone
29% identity, 92% coverage of query (94.4 bits)
2he5A Crystal structure of 17alpha-hydroxysteroid dehydrogenase in binary complex with NADP(h) in an open conformation
29% identity, 92% coverage of query (94.4 bits)
AKR1C4 / P17516 aldo-keto reductase family 1 member C4 (EC 1.1.1.213; EC 1.3.1.20; EC 1.1.1.225; EC 1.1.1.357) from Homo sapiens (see 9 papers)
AK1C4_HUMAN / P17516 Aldo-keto reductase family 1 member C4; 3-alpha-hydroxysteroid dehydrogenase type I; 3-alpha-HSD1; 3alpha-hydroxysteroid 3-dehydrogenase; Chlordecone reductase; CDR; Dihydrodiol dehydrogenase 4; DD-4; DD4; HAKRA; EC 1.1.1.-; EC 1.1.1.209; EC 1.1.1.210; EC 1.1.1.51; EC 1.1.1.53; EC 1.1.1.62; EC 1.1.1.357; EC 1.1.1.225 from Homo sapiens (Human) (see 11 papers)
P17516 3alpha-hydroxysteroid 3-dehydrogenase (EC 1.1.1.357) from Homo sapiens (see 4 papers)
29% identity, 91% coverage of query (94.0 bits)
Akr1a4 / Q9JII6 alcohol dehydrogenase [NADP+] (EC 1.1.1.19) from Mus musculus (see 4 papers)
AK1A1_MOUSE / Q9JII6 Aldo-keto reductase family 1 member A1; Alcohol dehydrogenase [NADP(+)]; Aldehyde reductase; Glucuronate reductase; Glucuronolactone reductase; EC 1.1.1.2; EC 1.1.1.372; EC 1.1.1.54; EC 1.1.1.19; EC 1.1.1.20 from Mus musculus (Mouse) (see 5 papers)
Q540D7 aldehyde dehydrogenase (NADP+) (EC 1.2.1.4) from Mus musculus (see paper)
Q9JII6 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Mus musculus (see paper)
27% identity, 92% coverage of query (94.0 bits)
I3ACR_SCHPO / O13848 NAD/NADP-dependent indole-3-acetaldehyde reductase; AKR3C2; EC 1.1.1.190; EC 1.1.1.191 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
SPAC19G12.09 / RF|NP_594424.1 NADH/NADPH dependent indole-3-acetaldehyde reductase AKR3C2 from Schizosaccharomyces pombe (see 3 papers)
29% identity, 91% coverage of query (94.0 bits)
2fvlA / P17516 Crystal structure of human 3-alpha hydroxysteroid/dihydrodiol dehydrogenase (akr1c4) complexed with NADP+
29% identity, 91% coverage of query (94.0 bits)
4fa3A Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 in complex with (r)-1-(naphthalen-2-ylsulfonyl)piperidine-3- carboxylic acid (86)
30% identity, 91% coverage of query (94.0 bits)
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