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Searching for up to 100 curated homologs for GFF3013 FitnessBrowser__Marino:GFF3013 (308 a.a.)

Found high-coverage hits (≥70%) to 54 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PS417_22140 glucose/xylose ABC transporter, permease component 2 from Pseudomonas simiae WCS417
    73% identity, 94% coverage of query (444 bits)

PfGW456L13_1895 ABC transporter for D-Galactose and D-Glucose, permease component 1 from Pseudomonas fluorescens GW456-L13
    73% identity, 94% coverage of query (443 bits)

TC 3.A.1.1.30 / Q88P37 GtsB (GLcF), component of Glucose porter, GtsABCD from Pseudomonas putida (strain KT2440) (see paper)
    73% identity, 94% coverage of query (439 bits)

Ac3H11_2064 glucose ABC transporter, permease component 1 from Acidovorax sp. GW101-3H11
    64% identity, 94% coverage of query (393 bits)

SMc04258 ABC transporter for D-Cellobiose and D-Salicin, permease component 2 from Sinorhizobium meliloti 1021
    44% identity, 100% coverage of query (248 bits)

XACH_HALVD / D4GP36 Xylose/arabinose import permease protein XacH from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    34% identity, 88% coverage of query (150 bits)

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Build an alignment for GFF3013 and 6 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 3.A.1.1.42 / TC 3.A.1.1.43 / Q9FBS6 Putative sugar-transporter integral membrane protein, component of α-glucoside uptake permease, Agl3E/Agl3F/Agl3G. Plays a role in normal morphogenesis and antibiotic production. Strongly induced by trehalose and melibiose, and weakly induced by lactose and glycerol but not glucose (Hillerich and Westpheling 2006).The operon is controlled by a GntR homologue, Agl3R, and downstream of the gntR from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    28% identity, 97% coverage of query (107 bits)

MELD_BACSU / O34706 Melibiose/raffinose/stachyose import permease protein MelD from Bacillus subtilis (strain 168) (see paper)
    30% identity, 78% coverage of query (104 bits)

GGTC_SYNY3 / Q55472 Osmoprotective compounds uptake permease protein GgtC from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
TC 3.A.1.1.32 / Q55472 Membrane bound sugar transport protein, component of The glucosylglycerol uptake transporter (functions in osmoprotection and also transports sucrose and trehalose (Mikkat and Hagemann, 2000) (most similar to 3.A.1.1.8) from Synechocystis sp. (strain PCC 6803) (see paper)
    28% identity, 78% coverage of query (100 bits)

SM_b20326 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 1 (ThuF) from Sinorhizobium meliloti 1021
TC 3.A.1.1.17 / Q9R9Q6 ThuF aka RB0312 aka SMB20326, component of Trehalose/maltose/sucrose porter (trehalose inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 3 papers)
    28% identity, 88% coverage of query (99.8 bits)

TC 3.A.1.1.19 / Q8L125 PalF, component of Platinose (isomaltulose) (6-O-α-D-glucopyranosyl-D-fructofuranose) porter from Agrobacterium tumefaciens (see 3 papers)
    28% identity, 88% coverage of query (97.4 bits)

TC 3.A.1.1.13 / Q97UZ0 GlcT, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see paper)
    28% identity, 90% coverage of query (97.4 bits)

SM_b21104 ABC transporter for L-Fucose, permease component 1 from Sinorhizobium meliloti 1021
    24% identity, 92% coverage of query (97.1 bits)

TC 3.A.1.1.41 / G4FGN7 ABC-type transporter, integral membrane subunit, component of Trehalose porter. Also binds sucrose (Boucher and Noll, 2011). Induced by glucose and trehalose. Directly regulated by trehalose-responsive regulator TreR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    28% identity, 91% coverage of query (96.7 bits)

TC 3.A.1.1.25 / Q72H67 Maltose transport system permease protein malF aka TT_C1628, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    28% identity, 80% coverage of query (95.5 bits)

TC 3.A.1.1.20 / Q7WWQ9 Transmembrane permease MsmF, component of The fructooligosaccharide porter, MsmEFGK from Lactobacillus acidophilus (see 2 papers)
msmF / GI|33149339 transmembrane permease MsmF from Lactobacillus acidophilus (see paper)
    30% identity, 74% coverage of query (94.7 bits)

NGCF_STRCO / O50500 Diacetylchitobiose uptake system permease protein NgcF from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    29% identity, 74% coverage of query (94.4 bits)

TC 3.A.1.1.28 / Q00750 MsmF aka SMU.879, component of The raffinose/stachyose transporter, MsmEFGK (MalK (3.A.1.1.27) can probably substitute for MsmK; Webb et al., 2008). This system may also transport melibiose, isomaltotriose and sucrose as well as isomaltosaccharides from Streptococcus mutans (see 2 papers)
    28% identity, 76% coverage of query (94.4 bits)

UgpA / b3452 sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA (EC 7.6.2.10) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
UgpA / P10905 sn-glycerol 3-phosphate ABC transporter membrane subunit UgpA (EC 7.6.2.10) from Escherichia coli (strain K12) (see 20 papers)
UGPA_ECOLI / P10905 sn-glycerol-3-phosphate transport system permease protein UgpA from Escherichia coli (strain K12) (see 5 papers)
P10905 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Escherichia coli (see paper)
TC 3.A.1.1.3 / P10905 UgpA aka B3452, component of Glycerol-phosphate porter. Transports both glycerol-3-P and glycerol-3-P diesters including glycerophosphocholine but not glycerol-2-P from Escherichia coli (see 5 papers)
    28% identity, 92% coverage of query (94.0 bits)

PGA1_c27940 N-Acetyl-D-glucosamine ABC transport system, permease component 1 from Phaeobacter inhibens BS107
    31% identity, 93% coverage of query (94.0 bits)

TC 3.A.1.1.37 / Q9WYB4 Predicted arabinoside porter. Regulated by arabinose-responsive regulator AraR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    27% identity, 92% coverage of query (94.0 bits)

MALF_THELN / O51924 Trehalose/maltose transport system permease protein MalF from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 3 papers)
    29% identity, 78% coverage of query (91.7 bits)

Dshi_1651 glucose/maltose/trehalose/sucrose ABC transporter, permease component 1 from Dinoroseobacter shibae DFL-12
    28% identity, 79% coverage of query (89.0 bits)

TC 3.A.1.1.18 / Q8RJU9 NgcF, component of N-Acetylglucosamine/N,N'-diacetyl chitobiose porter (NgcK (C) not identified) from Streptomyces olivaceoviridis (Streptomyces corchorusii) (see paper)
    26% identity, 85% coverage of query (85.9 bits)

SMc02872 ABC transporter for N-Acetyl-D-glucosamine, permease protein 1 from Sinorhizobium meliloti 1021
    30% identity, 79% coverage of query (82.4 bits)

TC 3.A.1.1.38 / Q9WYQ0 ABC-type transporter, integral membrane subunit, component of Inositol phosphate porter (Rodionova et al. 2013). Binds inositol phosphate with low Kd and inositol with a lower affinity from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    24% identity, 91% coverage of query (80.9 bits)

TC 3.A.1.1.21 / Q9L026 BxlF, component of The xylobiose porter; BxlEFG(K) from Streptomyces coelicolor (see paper)
    25% identity, 79% coverage of query (80.9 bits)

TC 3.A.1.1.11 / Q93KC0 TogM, component of Saturated and unsaturated oligogalacturonide transporter, TogMNAB (transports di- to tetrasaccharide pectin degradation products which consist of D-galacuronate, sometimes with 4-deoxy-L-threo-5-hexosulose uronate at the reducing end of the oligosaccharide) (Hugouvieux-Cotte-Pattat et al. 2001). Regulated by pectin utilization regulator KdgR from Erwinia chrysanthemi (see paper)
    28% identity, 79% coverage of query (80.9 bits)

HSERO_RS17005 ABC transporter for D-sorbitol/xylitol, permease component 1 from Herbaspirillum seropedicae SmR1
    26% identity, 74% coverage of query (79.7 bits)

TC 3.A.1.1.7 / O51924 MalF, component of Maltose/trehalose porter from Thermococcus litoralis (see paper)
    29% identity, 78% coverage of query (77.8 bits)

PGA1_c13200 ABC transporter for D-Sorbitol, permease component 2 from Phaeobacter inhibens BS107
    27% identity, 91% coverage of query (76.6 bits)

TC 3.A.1.1.45 / Q8NMV4 ABC-type sugar transport system, permease component, component of Maltose transporter, MusEFGKI from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
    25% identity, 75% coverage of query (76.3 bits)

sugA / P9WG03 ABC-type trehalose transporter integral membrane protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGA_MYCTU / P9WG03 Trehalose transport system permease protein SugA from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
TC 3.A.1.1.31 / O50452 PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGA, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
    28% identity, 94% coverage of query (75.5 bits)

PS417_12710 ABC transporter for D-Mannitol and D-Sorbitol, permease component 2 from Pseudomonas simiae WCS417
    25% identity, 72% coverage of query (74.3 bits)

Q6MNM0 ABC-type maltose transporter (EC 7.5.2.1) from Bdellovibrio bacteriovorus (see paper)
TC 3.A.1.1.51 / Q6MNM0 Maltose - maltoheptose transporter, MalEFGK from Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100)
    23% identity, 89% coverage of query (73.9 bits)

Pf6N2E2_1962 ABC transporter for D-sorbitol, permease component 1 from Pseudomonas fluorescens FW300-N2E2
    25% identity, 72% coverage of query (73.6 bits)

AO356_00020 ABC transporter for D-Sorbitol, permease component 2 from Pseudomonas fluorescens FW300-N2C3
    25% identity, 72% coverage of query (73.6 bits)

TC 3.A.1.1.49 / O30492 MtlF, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
    25% identity, 72% coverage of query (73.2 bits)

SM_b21220 ABC transporter for D-Glucosamine, permease component 2 from Sinorhizobium meliloti 1021
    29% identity, 76% coverage of query (73.2 bits)

mtlF / Q4KC56 polyol ABC-type transporter permease component MtlF from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    24% identity, 72% coverage of query (72.4 bits)

DASB_STRCO / Q9K490 Diacetylchitobiose uptake system permease protein DasB from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    24% identity, 84% coverage of query (70.9 bits)

Pf1N1B4_5113 sucrose ABC transporter, permease component 1 from Pseudomonas fluorescens FW300-N1B4
    26% identity, 79% coverage of query (70.9 bits)

TC 3.A.1.1.44 / Q9KZ07 Putative maltose permease, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    28% identity, 75% coverage of query (69.3 bits)

TC 3.A.1.1.50 / Q5SLB6 Sugar ABC transporter, permease protein, component of Probable glycerophosphocholine (GPC) uptake porter (Chandravanshi et al. 2016). The system may include a receptor and three membrane proteins (of 378 aas and 6 TMSs, 299 aas and 7 TMSs, and 113 aas and 3 TMSs (?). The ATPase has not been identified from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
    26% identity, 83% coverage of query (68.9 bits)

Dshi_0548 ABC transporter for Xylitol, permease component 1 from Dinoroseobacter shibae DFL-12
    26% identity, 80% coverage of query (68.6 bits)

7cagA / A0R2C2 Mycobacterium smegmatis lpqy-sugabc complex in the catalytic intermediate state (see paper)
    29% identity, 86% coverage of query (67.0 bits)

smoG / Q7CS30 ABC-type 3-(6-sulfo-α-D-quinovosyl)-sn-glycerol transporter permease subunit from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
    27% identity, 92% coverage of query (65.5 bits)

Ac3H11_2943 ABC transporter for D-Sorbitol, permease component 2 from Acidovorax sp. GW101-3H11
    23% identity, 71% coverage of query (65.5 bits)

TC 3.A.1.1.35 / G3LHZ0 GlpP, component of Glycerol uptake porter, GlpSTPQV from Rhizobium leguminosarum bv. viciae
    27% identity, 71% coverage of query (63.2 bits)

TC 3.A.1.1.6 / Q48396 CymF, component of Cyclodextrin porter from Klebsiella oxytoca (see paper)
    24% identity, 91% coverage of query (63.2 bits)

TC 3.A.1.1.48 / D6ZW63 MalF-type ABC sugar transport systems permease component, component of The lacto-N-biose I (LNB; Gal β-1,3-GlcNAc)/galacto-N-biose (GNB; Gal β-1,3-GalNAc) transporter from Bifidobacterium longum subsp. longum (strain JDM301)
    23% identity, 80% coverage of query (62.4 bits)

SM_b21653 ABC transporter for Lactose, permease component 1 from Sinorhizobium meliloti 1021
    24% identity, 93% coverage of query (62.4 bits)

TC 3.A.1.1.4 / P29823 LacF, component of Lactose porter from Agrobacterium radiobacter (see paper)
    26% identity, 79% coverage of query (62.4 bits)

ARAP_BACSU / P94529 Arabinooligosaccharides transport system permease protein AraP from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.1.34 / P94529 L-arabinose transport system permease protein AraP, component of The arabinosaccharide transporter AraNPQMsmX. Transports α-1,5-arabinooligosaccharides, at least up to four L-arabinosyl units; the key transporter for α-1,5-arabinotriose and α-1,5-arabinotetraose, but not for α-1,5-arabinobiose which is transported by AraE. MsmX is also used by the MdxEFG-MsmX system (3.A.1.1.36) (Ferreira and Sá-Nogueira, 2010). Involved in the uptake of pectin oligosaccharides with either MsmX or YurJ as the ATPase from Bacillus subtilis (see 4 papers)
araP / GB|CAB14834.1 L-arabinose transport system permease protein AraP from Bacillus subtilis (see 4 papers)
    25% identity, 71% coverage of query (55.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory