Sites on a Tree

 

Searching for up to 100 curated homologs for GFF3014 FitnessBrowser__psRCH2:GFF3014 (285 a.a.)

Found high-coverage hits (≥70%) to 8 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO353_17195 3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6) from Pseudomonas fluorescens FW300-N2E3
    87% identity, 100% coverage of query (519 bits)

PS417_06700 3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6) from Pseudomonas simiae WCS417
    87% identity, 100% coverage of query (518 bits)

PfGW456L13_4592 3-oxoadipate CoA-transferase subunit A (EC 2.8.3.6) from Pseudomonas fluorescens GW456-L13
    86% identity, 100% coverage of query (515 bits)

CATI_PSEKB / Q8VPF3 3-oxoadipate CoA-transferase subunit A; 3-oxoadipate:succinyl-CoA transferase subunit A; Beta-ketoadipate:succinyl-CoA transferase subunit A; EC 2.8.3.6 from Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13) (see paper)
Q8VPF3 3-oxoadipate CoA-transferase (subunit 2/2) (EC 2.8.3.6) from Pseudomonas knackmussii (see 2 papers)
    86% identity, 99% coverage of query (514 bits)

gctA / Q59111 GctA (EC 2.8.3.12) from Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) (see paper)
Q59111 glutaconate CoA-transferase (subunit 2/2) (EC 2.8.3.12) from Acidaminococcus fermentans (see paper)
    34% identity, 100% coverage of query (133 bits)

Build an alignment

Build an alignment for GFF3014 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

6co9A / Q0S7P9 Crystal structure of rhodococcus jostii rha1 ipdab cochea-coa complex (see paper)
    27% identity, 98% coverage of query (77.0 bits)

IPDA_RHOJR / Q0S7P9 Cholesterol ring-cleaving hydrolase IpdA subunit; (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase alpha subunit; COCHEA-CoA hydrolase alpha subunit; EC 4.1.99.- from Rhodococcus jostii (strain RHA1) (see 2 papers)
    27% identity, 98% coverage of query (76.6 bits)

ipdA / P9WPW1 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA ligase α subunit from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 6 papers)
IPDA_MYCTU / P9WPW1 Cholesterol ring-cleaving hydrolase IpdA subunit; (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase alpha subunit; COCHEA-CoA hydrolase alpha subunit; EC 4.1.99.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
    30% identity, 96% coverage of query (75.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory