Searching for up to 100 curated homologs for GFF3090 FitnessBrowser__Marino:GFF3090 (240 a.a.)
Found high-coverage hits (≥70%) to 44 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.3.11 / O50183 AotP aka AotM aka PA0890, component of Arginine/ornithine (but not lysine) porter from Pseudomonas aeruginosa (see 2 papers)
53% identity, 90% coverage of query (217 bits)
Pf1N1B4_3433 ABC transporter for L-Arginine and L-Citrulline, permease component 2 from Pseudomonas fluorescens FW300-N1B4
50% identity, 95% coverage of query (207 bits)
PS417_21735 ABC transporter for L-Arginine, permease component 2 from Pseudomonas simiae WCS417
52% identity, 78% coverage of query (207 bits)
AO353_03045 ABC transporter for L-Arginine and L-Citrulline, permease component 1 from Pseudomonas fluorescens FW300-N2E3
50% identity, 95% coverage of query (202 bits)
BPHYT_RS07680 ABC transporter for L-Arginine, permease component 1 from Burkholderia phytofirmans PsJN
49% identity, 88% coverage of query (198 bits)
AO356_18710 L-Arginine ABC transporter, permease component 1 from Pseudomonas fluorescens FW300-N2C3
51% identity, 78% coverage of query (192 bits)
Pf6N2E2_5662 L-Arginine ABC transporter, permease protein AotM from Pseudomonas fluorescens FW300-N2E2
50% identity, 78% coverage of query (191 bits)
TC 3.A.1.3.6 / P35113 NocM aka ATU6025 aka AGR_PTI_65, component of Nopaline porter from Agrobacterium tumefaciens (see 3 papers)
48% identity, 80% coverage of query (187 bits)
HisM / b2307 lysine/arginine/ornithine ABC transporter / histidine ABC transporter, membrane subunit HisM (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
HISM_ECOLI / P0AEU3 Histidine/lysine/arginine/ornithine transport system permease protein HisM from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.29 / P0AEU3 Histidine transport system permease protein HisM, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
46% identity, 90% coverage of query (185 bits)
AO356_09910 ABC transporter for L-Lysine, permease component 2 from Pseudomonas fluorescens FW300-N2C3
47% identity, 86% coverage of query (184 bits)
HISM_SALTY / P0A2I7 Histidine/lysine/arginine/ornithine transport system permease protein HisM from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 5 papers)
TC 3.A.1.3.1 / P0A2I7 Histidine transport system permease protein HisM aka STM2352, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
46% identity, 90% coverage of query (182 bits)
TC 3.A.1.3.23 / Q9HU29 Amino acid (Lysine/arginine/ornithine/histidine/octopine) ABC transporter membrane protein, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
45% identity, 86% coverage of query (173 bits)
TC 3.A.1.3.5 / P35114 OCM1 aka OccM, component of Octopine porter from Agrobacterium tumefaciens (see 2 papers)
40% identity, 94% coverage of query (165 bits)
Pf6N2E2_2960 ABC transporter for L-Lysine, permease component 2 from Pseudomonas fluorescens FW300-N2E2
42% identity, 92% coverage of query (159 bits)
AO356_05505 ABC transporter for L-Lysine, permease component 2 from Pseudomonas fluorescens FW300-N2C3
41% identity, 92% coverage of query (158 bits)
BPHYT_RS24010 L-histidine ABC transporter, permease component 2 from Burkholderia phytofirmans PsJN
41% identity, 73% coverage of query (152 bits)
SMc00138 L-lysine ABC transporter, permease component 2 from Sinorhizobium meliloti 1021
38% identity, 88% coverage of query (142 bits)
PP_3595 L-lysine and D-lysine ABC transporter, permease component 2 from Pseudomonas putida KT2440
39% identity, 70% coverage of query (126 bits)
ArtM / b0861 L-arginine ABC transporter membrane subunit ArtM (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see paper)
ArtM / P0AE30 L-arginine ABC transporter membrane subunit ArtM (EC 7.4.2.1) from Escherichia coli (strain K12) (see 2 papers)
ARTM_ECOLI / P0AE30 Arginine ABC transporter permease protein ArtM from Escherichia coli (strain K12) (see paper)
TC 3.A.1.3.3 / P0AE30 Arginine transport system permease protein ArtM aka B0861, component of Arginine porter from Escherichia coli (see 6 papers)
34% identity, 90% coverage of query (125 bits)
ARGU_CORGL / Q8NQU3 Arginine transport system permease protein ArgU from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
36% identity, 85% coverage of query (124 bits)
ARTQ_BACSU / P54536 Arginine transport system permease protein ArtQ from Bacillus subtilis (strain 168) (see paper)
33% identity, 88% coverage of query (112 bits)
4ymtC / Q8RCC3 Crystal structure of an amino acid abc transporter complex with arginines (see paper)
35% identity, 85% coverage of query (110 bits)
4ymwC Crystal structure of an amino acid abc transporter with histidines
35% identity, 85% coverage of query (110 bits)
TC 3.A.1.3.12 / P73544 BgtB aka GLNH aka SLL1270, component of Arginine/lysine/histidine/glutamine porter (see paper)
32% identity, 93% coverage of query (108 bits)
Ac3H11_2554 ABC transporter for L-Histidine, permease component 1 from Acidovorax sp. GW101-3H11
31% identity, 88% coverage of query (106 bits)
TcyL / b1918 cystine ABC transporter membrane subunit (EC 7.4.2.12) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
tcyL / P0AFT2 cystine ABC transporter membrane subunit (EC 7.4.2.12) from Escherichia coli (strain K12) (see 3 papers)
TCYL_ECOLI / P0AFT2 L-cystine transport system permease protein TcyL from Escherichia coli (strain K12) (see 5 papers)
TC 3.A.1.3.10 / P0AFT2 Inner membrane amino-acid ABC transporter permease protein YECS CysY aka B1918, component of Cystine/cysteine/diaminopimelate transporter, CysXYZ; these proteins are also designated FliY/YecS/YecC from Escherichia coli (see 4 papers)
33% identity, 88% coverage of query (105 bits)
TC 3.A.1.3.17 / Q8YSA2 Basic amino acid uptake transporter, BgtAB (see paper)
31% identity, 85% coverage of query (103 bits)
TCYL_BACSU / O34315 L-cystine transport system permease protein TcyL from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.3.13 / O34315 TcyL (YtmL), component of Uptake system for L-cystine (Km=2.5 μM), L-cystathionine, L-djenkolate ( 2-amino-3-[(2-amino-3-hydroxy-3-oxopropyl)sulfanylmethylsulfanyl] propanoic acid), and S-methyl-L-cysteine from Bacillus subtilis (see 4 papers)
30% identity, 86% coverage of query (103 bits)
TCYM_BACSU / O34931 L-cystine transport system permease protein TcyM from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.3.13 / O34931 TcyM (YtmM), component of Uptake system for L-cystine (Km=2.5 μM), L-cystathionine, L-djenkolate ( 2-amino-3-[(2-amino-3-hydroxy-3-oxopropyl)sulfanylmethylsulfanyl] propanoic acid), and S-methyl-L-cysteine from Bacillus subtilis (see 4 papers)
32% identity, 86% coverage of query (101 bits)
Build an alignment for GFF3090 and 29 homologs with ≥ 30% identity
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TC 3.A.1.3.25 / Q9CES5 Glutamine ABC transporter permease and substrate binding protein protein, component of Glutamine transporter, GlnQP. Takes up glutamine, asparagine and glutamate which compete for each other for binding both substrate and the transmembrane protein constituent of the system (Fulyani et al. 2015). Tandem substrate binding domains (SBDs) differ in substrate specificity and affinity, allowing cells to efficiently accumulate different amino acids via a single ABC transporter. Analysis revealed the roles of individual residues in determining the substrate affinity from Lactococcus lactis subsp. lactis (strain IL1403)
27% identity, 86% coverage of query (95.9 bits)
TC 3.A.1.3.5 / P0A4N5 Octopine transport system permease protein occQ, component of Octopine porter from Agrobacterium tumefaciens (see 2 papers)
35% identity, 72% coverage of query (94.7 bits)
GltJ / b0654 glutamate/aspartate ABC transporter membrane subunit GltJ (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GltJ / P0AER3 glutamate/aspartate ABC transporter membrane subunit GltJ (EC 7.4.2.1) from Escherichia coli (strain K12) (see 2 papers)
GLTJ_ECOLI / P0AER3 Glutamate/aspartate import permease protein GltJ from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.3.4 / P0AER3 Glutamate/aspartate transport system permease protein GltJ aka B0654, component of Glutamate/aspartate porter from Escherichia coli (see 4 papers)
31% identity, 90% coverage of query (94.0 bits)
AO356_05500 ABC transporter for L-Lysine, permease component 1 from Pseudomonas fluorescens FW300-N2C3
34% identity, 70% coverage of query (93.6 bits)
TCYB_BACSU / P42200 L-cystine transport system permease protein TcyB from Bacillus subtilis (strain 168) (see paper)
TC 3.A.1.3.14 / P42200 TcyB (YckJ), component of Uptake system for L-cystine from Bacillus subtilis (see 4 papers)
30% identity, 87% coverage of query (92.4 bits)
AO353_21720 ABC transporter for D-glucosamine, permease component 2 from Pseudomonas fluorescens FW300-N2E3
25% identity, 88% coverage of query (90.5 bits)
AO356_00470 ABC transporter for D-Glucosamine, permease component 1 from Pseudomonas fluorescens FW300-N2C3
Pf6N2E2_2051 ABC transporter for D-Glucosamine Hydrochloride, permease component 1 from Pseudomonas fluorescens FW300-N2E2
25% identity, 88% coverage of query (89.4 bits)
YXEN_BACSU / P54953 Probable amino-acid permease protein YxeN from Bacillus subtilis (strain 168) (see paper)
32% identity, 72% coverage of query (89.4 bits)
TC 3.A.1.3.22 / Q9I404 Amino acid ABC transporter membrane protein, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
28% identity, 87% coverage of query (88.2 bits)
TC 3.A.1.3.18 / Q8YPM7 NatH, component of Acidic and neutral amino acid uptake transporter NatFGH/BgtA. BgtA is shared with BgtAB (see paper)
31% identity, 87% coverage of query (85.9 bits)
Pf1N1B4_773 ABC transporter for L-asparagine and L-glutamate, permease subunit 2 from Pseudomonas fluorescens FW300-N1B4
28% identity, 86% coverage of query (85.5 bits)
PfGW456L13_4772 ABC transporter for L-Asparagine and possibly other L-amino acids, permease component 2 from Pseudomonas fluorescens GW456-L13
29% identity, 88% coverage of query (85.1 bits)
GLNM_BACSU / O34671 Probable glutamine ABC transporter permease protein GlnM from Bacillus subtilis (strain 168) (see paper)
31% identity, 88% coverage of query (84.0 bits)
TC 3.A.1.3.19 / Q88NY3 PP1070, component of Acidic amino acid uptake porter, AatJMQP from Pseudomonas putida (strain KT2440) (see paper)
31% identity, 79% coverage of query (83.2 bits)
Pf1N1B4_3432 ABC transporter for L-Arginine and L-Citrulline, permease component 1 from Pseudomonas fluorescens FW300-N1B4
27% identity, 86% coverage of query (83.2 bits)
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Lawrence Berkeley National Laboratory