Searching for up to 100 curated homologs for GFF3292 FitnessBrowser__Marino:GFF3292 (530 a.a.)
Found high-coverage hits (≥70%) to 55 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q9I0K4 isocitrate lyase (EC 4.1.3.1) from Pseudomonas aeruginosa (see 2 papers)
81% identity, 99% coverage of query (892 bits)
Psest_2014 Isocitrate lyase (EC 4.1.3.1) from Pseudomonas stutzeri RCH2
79% identity, 99% coverage of query (877 bits)
A8C781 isocitrate lyase (EC 4.1.3.1) from Azotobacter vinelandii (see paper)
78% identity, 99% coverage of query (874 bits)
6g1oA / Q9I0K4 Structure of pseudomonas aeruginosa isocitrate lyase, icl (see paper)
81% identity, 91% coverage of query (814 bits)
Q93R40 isocitrate lyase (EC 4.1.3.1) from Colwellia maris (see paper)
73% identity, 96% coverage of query (773 bits)
A8C5K8 isocitrate lyase (EC 4.1.3.1) from Colwellia psychrerythraea (see paper)
72% identity, 97% coverage of query (766 bits)
ACEA_HYPME / O50078 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1 from Hyphomicrobium methylovorum (see paper)
57% identity, 100% coverage of query (611 bits)
Build an alignment for GFF3292 and 7 homologs with ≥ 30% identity
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Q8RPZ0 isocitrate lyase (EC 4.1.3.1) from Streptomyces clavuligerus (see paper)
27% identity, 95% coverage of query (138 bits)
GCP_CAEEL / Q10663 Bifunctional glyoxylate cycle protein; Gex-3-interacting protein 7; EC 4.1.3.1; EC 2.3.3.9 from Caenorhabditis elegans (see 2 papers)
29% identity, 77% coverage of query (135 bits)
ACEA_CORGL / P42449 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
27% identity, 92% coverage of query (132 bits)
Pf1N1B4_4042 Isocitrate lyase (EC 4.1.3.1) from Pseudomonas fluorescens FW300-N1B4
27% identity, 95% coverage of query (130 bits)
Shew_1276 Isocitrate lyase (EC 4.1.3.1) from Shewanella loihica PV-4
28% identity, 82% coverage of query (129 bits)
Sama_2380 Isocitrate lyase (EC 4.1.3.1) from Shewanella amazonensis SB2B
29% identity, 79% coverage of query (129 bits)
icl / CAA82555.1 isocitrate lyase from Rhodococcus fascians (see paper)
26% identity, 92% coverage of query (126 bits)
5e9gD / P0CT06 Structural insights of isocitrate lyases from magnaporthe oryzae (see paper)
28% identity, 79% coverage of query (126 bits)
Q97YI8 isocitrate lyase (EC 4.1.3.1) from Saccharolobus solfataricus (see paper)
27% identity, 92% coverage of query (126 bits)
SO1484 Isocitrate lyase (EC 4.1.3.1) from Shewanella oneidensis MR-1
28% identity, 77% coverage of query (125 bits)
7rbxC / Q2YQA0 Crystal structure of isocitrate lyase and phosphorylmutase:isocitrate lyase from brucella melitensis biovar abortus 2308 bound to itaconic acid (see paper)
28% identity, 77% coverage of query (124 bits)
A0A3S5YB92 isocitrate lyase (EC 4.1.3.1) from Rhodococcus hoagii (see paper)
26% identity, 92% coverage of query (123 bits)
6lrtA / A9WDE7 Crystal structure of isocitrate lyase (caur_3889) from chloroflexus aurantiacus in complex with isocitrate and manganese ion
26% identity, 96% coverage of query (123 bits)
Icl / b4015 isocitrate lyase (EC 4.1.3.1) from Escherichia coli K-12 substr. MG1655 (see paper)
aceA / P0A9G6 isocitrate lyase (EC 4.1.3.1) from Escherichia coli (strain K12) (see 25 papers)
ACEA_ECOLI / P0A9G6 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1 from Escherichia coli (strain K12) (see 7 papers)
28% identity, 77% coverage of query (122 bits)
BWI76_RS01665 Isocitrate lyase (EC 4.1.3.1) from Klebsiella michiganensis M5al
29% identity, 77% coverage of query (122 bits)
7cmyC / Q81GQ9 Isocitrate lyase from bacillus cereus atcc 14579 in complex with magnessium ion, glyoxylate, and succinate
27% identity, 85% coverage of query (122 bits)
1igwC / P0A9G6 Crystal structure of the isocitrate lyase from the a219c mutant of escherichia coli (see paper)
27% identity, 77% coverage of query (121 bits)
5e9gC Structural insights of isocitrate lyases from magnaporthe oryzae
28% identity, 78% coverage of query (121 bits)
ACEA_KLULA / Q8NJ72 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) (see paper)
26% identity, 84% coverage of query (120 bits)
7ebeA / Q9P8Q7 Crystal structure of isocitrate lyase-1 from candida albicans (see paper)
28% identity, 82% coverage of query (120 bits)
ICL1 Isocitrate lyase from Candida albicans (see 2 papers)
28% identity, 82% coverage of query (120 bits)
Q9P8Q7 isocitrate lyase (EC 4.1.3.1) from Candida albicans (see 2 papers)
28% identity, 82% coverage of query (120 bits)
ACEA_PYRO7 / P0CT06 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Pyricularia oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Magnaporthe oryzae) (see paper)
P0CT06 isocitrate lyase (EC 4.1.3.1) from Pyricularia oryzae (see paper)
ICL1 isocitrate lyase from Magnaporthe grisea 70-15 (see paper)
27% identity, 82% coverage of query (118 bits)
ACEA_ORYSJ / Q6Z6M4 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1 from Oryza sativa subsp. japonica (Rice) (see 3 papers)
28% identity, 92% coverage of query (118 bits)
Ac3H11_2831 Isocitrate lyase (EC 4.1.3.1) from Acidovorax sp. GW101-3H11
27% identity, 78% coverage of query (118 bits)
5e9gB / P0CT06 Structural insights of isocitrate lyases from magnaporthe oryzae (see paper)
26% identity, 79% coverage of query (114 bits)
6c4aA / P9WKK7 Crystal structure of 3-nitropropionate modified isocitrate lyase from mycobacterium tuberculosis with pyruvate (see paper)
25% identity, 95% coverage of query (110 bits)
icl / P9WKK7 isocitrate lyase subunit (EC 4.1.3.1) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
ACEA1_MYCTE / H8EVV4 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC 4.1.3.1; EC 4.1.3.30 from Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman) (see paper)
ACEA1_MYCBO / P0A5H4 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; EC 4.1.3.1 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
ACEA1_MYCTO / P9WKK6 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC 4.1.3.1; EC 4.1.3.30 from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) (see 3 papers)
ACEA_MYCTU / P9WKK7 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 7 papers)
P9WKK7 isocitrate lyase (EC 4.1.3.1) from Mycobacterium tuberculosis (see 4 papers)
25% identity, 95% coverage of query (110 bits)
7rb1A Isocitrate lyase-1 from mycobacterium tuberculosis covalently modified by 5-descarboxy-5-nitro-d-isocitric acid
25% identity, 95% coverage of query (110 bits)
6wsiA Intact cis-2,3-epoxysuccinic acid bound to isocitrate lyase-1 from mycobacterium tuberculosis
25% identity, 95% coverage of query (110 bits)
6vb9A Covalent adduct of cis-2,3-epoxysuccinic acid with isocitrate lyase-1 from mycobacterium tuberculosis
25% identity, 95% coverage of query (110 bits)
5dqlA Crystal structure of 2-vinyl glyoxylate modified isocitrate lyase from mycobacterium tuberculosis
25% identity, 95% coverage of query (110 bits)
6xppA Crystal structure of itaconate modified mycobaterium tuberculosis isocitrate lyase
25% identity, 95% coverage of query (110 bits)
ACEA_BRANA / P25248 Isocitrate lyase; ICL; Isocitrase; Isocitratsysase; EC 4.1.3.1 from Brassica napus (Rape) (see paper)
28% identity, 84% coverage of query (109 bits)
ACEA_YEAST / P28240 Isocitrate lyase; ICL; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 19 papers)
26% identity, 82% coverage of query (108 bits)
icl / P28297 isocitrate lyase (EC 4.1.3.1) from Arabidopsis thaliana (see paper)
ACEA_ARATH / P28297 Isocitrate lyase; ICL; Isocitrase; Isocitratsysase; EC 4.1.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
27% identity, 84% coverage of query (108 bits)
ACEA_EMENI / P28298 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
acuD / PDB|1DQU_A isocitrate lyase; EC 4.1.3.1 from Emericella nidulans (see 4 papers)
27% identity, 82% coverage of query (106 bits)
1f8iA Crystal structure of isocitrate lyase:nitropropionate:glyoxylate complex from mycobacterium tuberculosis
25% identity, 95% coverage of query (106 bits)
5e9fD / P0CT06 Structural insights of isocitrate lyases from magnaporthe oryzae (see paper)
28% identity, 78% coverage of query (104 bits)
Q5YLB6 isocitrate lyase (EC 4.1.3.1) from Paracoccidioides brasiliensis (see paper)
28% identity, 82% coverage of query (103 bits)
5e9fA Structural insights of isocitrate lyases from magnaporthe oryzae
26% identity, 78% coverage of query (97.1 bits)
ACEB_YARLI / Q6BZP5 2-methylisocitrate lyase, mitochondrial; EC 4.1.3.30 from Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica) (see paper)
26% identity, 77% coverage of query (96.3 bits)
ACEA_NEUCR / P28299 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 2 papers)
26% identity, 92% coverage of query (95.5 bits)
ACEA_LEPMC / Q86ZF1 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) (see paper)
25% identity, 82% coverage of query (95.1 bits)
5e9fB / P0CT06 Structural insights of isocitrate lyases from magnaporthe oryzae (see paper)
27% identity, 78% coverage of query (94.7 bits)
Q4HYR2 isocitrate lyase (EC 4.1.3.1) from Fusarium graminearum (see paper)
26% identity, 82% coverage of query (93.2 bits)
5e9hA / Q4HYR2 Structural insights of isocitrate lyases from fusarium graminearum (see paper)
25% identity, 89% coverage of query (92.4 bits)
1igwA / P0A9G6 Crystal structure of the isocitrate lyase from the a219c mutant of escherichia coli (see paper)
26% identity, 77% coverage of query (91.7 bits)
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Lawrence Berkeley National Laboratory