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Searching for up to 100 curated homologs for GFF3304 FitnessBrowser__psRCH2:GFF3304 (369 a.a.)

Found high-coverage hits (≥70%) to 62 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

GLYOX_PSEPK / Q88Q83 Glycine oxidase; GO; EC 1.4.3.19 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
Q88Q83 glycine oxidase (EC 1.4.3.19) from Pseudomonas putida (see paper)
    70% identity, 99% coverage of query (522 bits)

dada* / AAB39269.1 dada* from Pseudomonas aeruginosa (see 2 papers)
    70% identity, 95% coverage of query (513 bits)

L7T8Y9 glycine oxidase (EC 1.4.3.19) from Bacillus cereus (see 2 papers)
    32% identity, 94% coverage of query (189 bits)

7cyxA / Q81HQ7 Crystal strcuture of glycine oxidase from bacillus cereus atcc 14579 (see paper)
    32% identity, 94% coverage of query (184 bits)

hcnC / O85228 hydrogen cyanide synthase HcnC subunit (EC 1.4.99.5) from Pseudomonas protegens (strain DSM 19095 / LMG 27888 / CFBP 6595 / CHA0) (see paper)
HCNC_PSEPH / O85228 Hydrogen cyanide synthase subunit HcnC; HcnC; Glycine dehydrogenase (cyanide-forming); EC 1.4.99.5 from Pseudomonas protegens (strain DSM 19095 / LMG 27888 / CFBP 6595 / CHA0) (see 3 papers)
    30% identity, 96% coverage of query (160 bits)

C7E717 glycine dehydrogenase (cyanide-forming) (subunit 1/3) (EC 1.4.99.5) from Pseudomonas fluorescens (see paper)
    30% identity, 96% coverage of query (160 bits)

HCNC_PSEAE / G3XD12 Hydrogen cyanide synthase subunit HcnC; HcnC; Glycine dehydrogenase (cyanide-forming); EC 1.4.99.5 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 6 papers)
    30% identity, 98% coverage of query (156 bits)

3if9A / O31616 Crystal structure of glycine oxidase g51s/a54r/h244a mutant in complex with inhibitor glycolate (see paper)
    31% identity, 90% coverage of query (155 bits)

thiO / O31616 glycine oxidase monomer (EC 1.4.3.19; EC 1.4.3.3) from Bacillus subtilis (strain 168) (see 3 papers)
GLYOX_BACSU / O31616 Glycine oxidase; GO; EC 1.4.3.19 from Bacillus subtilis (strain 168) (see 5 papers)
    31% identity, 90% coverage of query (154 bits)

1ng3A Complex of thio (glycine oxidase) with acetyl-glycine
    30% identity, 90% coverage of query (152 bits)

GLYOX_BACLI / S5FMM4 Glycine oxidase; GO; BliGO; EC 1.4.3.19 from Bacillus licheniformis (see paper)
S5FMM4 glycine oxidase (EC 1.4.3.19) from Bacillus licheniformis (see paper)
    30% identity, 90% coverage of query (137 bits)

Build an alignment

Build an alignment for GFF3304 and 11 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

4yshA / Q5L2C2 Crystal structure of glycine oxidase from geobacillus kaustophilus
    29% identity, 92% coverage of query (120 bits)

4yshB Crystal structure of glycine oxidase from geobacillus kaustophilus
    29% identity, 92% coverage of query (119 bits)

GLYOX_GEOKA / Q5L2C2 Glycine oxidase; GO; GOX; GOXK; EC 1.4.3.19 from Geobacillus kaustophilus (strain HTA426) (see paper)
Q5L2C2 glycine oxidase (EC 1.4.3.19) from Geobacillus kaustophilus (see paper)
    29% identity, 92% coverage of query (115 bits)

AZOBR_RS08020 D-alanine dehydrogenase (EC 1.4.99.-) from Azospirillum brasilense Sp245
    27% identity, 95% coverage of query (110 bits)

DADA_KLEAE / O30745 D-amino acid dehydrogenase; D-alanine dehydrogenase; EC 1.4.99.- from Klebsiella aerogenes (Enterobacter aerogenes) (see paper)
    27% identity, 96% coverage of query (110 bits)

DadR / b1189 D-amino acid dehydrogenase (EC 1.4.5.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
dadA / P0A6J5 D-amino acid dehydrogenase (EC 1.4.5.1) from Escherichia coli (strain K12) (see 22 papers)
DADA_ECOLI / P0A6J5 D-amino acid dehydrogenase; D-alanine dehydrogenase; EC 1.4.99.- from Escherichia coli (strain K12) (see 4 papers)
dadA / AAC36880.1 D-amino acid dehydrogenase from Escherichia coli (see paper)
    27% identity, 96% coverage of query (106 bits)

DADA1_PSEAE / Q9HTQ0 D-amino acid dehydrogenase 1; D-alanine dehydrogenase 1; EC 1.4.99.- from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9HTQ0 D-arginine dehydrogenase (EC 1.4.99.6) from Pseudomonas aeruginosa (see paper)
    27% identity, 95% coverage of query (106 bits)

Psest_3793 D-alanine dehydrogenase (EC 1.4.99.-) from Pseudomonas stutzeri RCH2
    27% identity, 95% coverage of query (100 bits)

6j38A / X5IYZ1 Crystal structure of cmis2 (see paper)
    29% identity, 92% coverage of query (99.4 bits)

6j39A Crystal structure of cmis2 with inhibitor
    29% identity, 92% coverage of query (99.4 bits)

6pxsA / Q11HA4 Crystal structure of iminodiacetate oxidase (idaa) from chelativorans sp. Bnc1 (see paper)
    30% identity, 97% coverage of query (97.1 bits)

Q51890 L-amino-acid oxidase (EC 1.4.3.2) from Proteus mirabilis (see paper)
aad / AAA86752.1 amino acid deaminase from Proteus mirabilis (see paper)
    23% identity, 96% coverage of query (96.3 bits)

lhpB / Q9I477 D-hydroxyproline dehydrogenase β subunit from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    28% identity, 98% coverage of query (95.9 bits)

2gagB Heteroteterameric sarcosine: structure of a diflavin metaloenzyme at 1.85 a resolution
    24% identity, 96% coverage of query (95.1 bits)

Q8U1G2 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus furiosus (see paper)
    25% identity, 89% coverage of query (94.0 bits)

mabO / Q8GAI3 4-methylaminobutyrate oxidase (demethylating) (EC 1.5.3.19) from Paenarthrobacter nicotinovorans (see 2 papers)
MABO1_PAENI / Q8GAI3 4-methylaminobutanoate oxidase (formaldehyde-forming); MABO; Demethylating gamma-N-methylaminobutyrate oxidase; Gamma-N-methylaminobutyrate oxidase 1; EC 1.5.3.19 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see 2 papers)
    28% identity, 95% coverage of query (93.6 bits)

5i39A / Q9LCB2 High resolution structure of l-amino acid deaminase from proteus vulgaris with the deletion of the specific insertion sequence (see paper)
    23% identity, 96% coverage of query (92.0 bits)

amaD / Q88GX1 D-lysine oxidase (EC 1.4.3.3) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
    24% identity, 97% coverage of query (89.7 bits)

TSOXB_ARTSP / Q9AGP3 Sarcosine oxidase subunit beta; Sarcosine oxidase subunit B; Sarcosine oxidase (5,10-methylenetetrahydrofolate-forming) subunit beta; Tetrameric sarcosine oxidase subunit beta; TSOX subunit beta; EC 1.5.3.24 from Arthrobacter sp.
    24% identity, 85% coverage of query (88.6 bits)

soxB / P40875 sarcosine oxidase β subunit (EC 1.5.3.24) from Corynebacterium sp. (strain P-1) (see 3 papers)
TSOXB_CORS1 / P40875 Sarcosine oxidase subunit beta; Sarcosine oxidase subunit B; Sarcosine oxidase (5,10-methylenetetrahydrofolate-forming) subunit beta; Tetrameric sarcosine oxidase subunit beta; TSOX subunit beta; EC 1.5.3.24 from Corynebacterium sp. (strain P-1) (see 7 papers)
    24% identity, 85% coverage of query (88.2 bits)

Q8U022 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus furiosus (see paper)
    25% identity, 90% coverage of query (87.8 bits)

O59445 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus horikoshii (see paper)
    24% identity, 90% coverage of query (86.7 bits)

Q5JFG7 proline dehydrogenase (EC 1.5.5.2) from Thermococcus kodakarensis (see paper)
    23% identity, 89% coverage of query (84.3 bits)

ooxB / Q59159 octopine oxidase subunit B from Agrobacterium tumefaciens (strain Ach5) (see paper)
    24% identity, 99% coverage of query (83.6 bits)

Q76M73 proline dehydrogenase (EC 1.5.5.2) from Thermococcus profundus (see 2 papers)
    25% identity, 89% coverage of query (82.8 bits)

1y56B / O59089 Crystal structure of l-proline dehydrogenase from p.Horikoshii (see paper)
    22% identity, 89% coverage of query (82.4 bits)

O59089 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus horikoshii (see paper)
    22% identity, 89% coverage of query (82.4 bits)

5hxwA / Q9LCB2 L-amino acid deaminase from proteus vulgaris (see paper)
    22% identity, 96% coverage of query (82.4 bits)

Q5JFG2 proline dehydrogenase (EC 1.5.5.2) from Thermococcus kodakarensis (see paper)
    25% identity, 89% coverage of query (81.3 bits)

DMGDH / Q9UI17 dimethylglycine dehydrogenase (EC 1.5.8.4) from Homo sapiens (see 6 papers)
M2GD_HUMAN / Q9UI17 Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; EC 1.5.8.4 from Homo sapiens (Human) (see 2 papers)
Q9UI17 dimethylglycine dehydrogenase (EC 1.5.8.4) from Homo sapiens (see 2 papers)
    26% identity, 96% coverage of query (80.9 bits)

Q9LCB2 L-amino-acid oxidase (EC 1.4.3.2) from Proteus vulgaris (see paper)
    22% identity, 96% coverage of query (79.7 bits)

Dmgdh / Q63342 dimethylglycine dehydrogenase, mitochondrial (EC 1.5.8.4) from Rattus norvegicus (see 9 papers)
M2GD_RAT / Q63342 Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; EC 1.5.8.4 from Rattus norvegicus (Rat) (see 3 papers)
Q63342 dimethylglycine dehydrogenase (EC 1.5.8.4) from Rattus norvegicus (see 3 papers)
    26% identity, 96% coverage of query (78.6 bits)

4pabB / Q63342 Crystal structure of the precursor form of rat dmgdh complexed with tetrahydrofolate (see paper)
    26% identity, 96% coverage of query (78.6 bits)

5fjmA / A0A158RFS7 Structure of l-amino acid deaminase from proteus myxofaciens (see paper)
    23% identity, 93% coverage of query (77.8 bits)

5fjnA Structure of l-amino acid deaminase from proteus myxofaciens in complex with anthranilate
    23% identity, 93% coverage of query (77.8 bits)

Q9DBT9 dimethylglycine dehydrogenase (EC 1.5.8.4) from Mus musculus (see paper)
    25% identity, 96% coverage of query (77.4 bits)

Q5RKL4 dimethylglycine dehydrogenase (EC 1.5.8.4) from Rattus norvegicus (see paper)
    25% identity, 96% coverage of query (76.6 bits)

B2ZHY0 L-amino-acid oxidase (EC 1.4.3.2) from Proteus mirabilis (see paper)
    21% identity, 97% coverage of query (74.7 bits)

7xxpA F316a-glycine-streptothricin f complex
    29% identity, 93% coverage of query (70.9 bits)

7xxmA Orf1-glycine-4-aminobutylthricin complex
    29% identity, 93% coverage of query (70.1 bits)

8griF / A0A125SZC1 Orf1-e312a-glycine-glycylthricin (see paper)
    28% identity, 93% coverage of query (67.8 bits)

lhpB / Q88NF6 D-hydroxyproline dehydrogenase subunit from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
    26% identity, 91% coverage of query (63.5 bits)

RR42_RS25930 glycine dehydrogenase (deaminating) (EC 1.4.1.10) from Cupriavidus basilensis FW507-4G11
    22% identity, 93% coverage of query (63.2 bits)

noxB / Q59157 nopaline oxidase subunit B from Rhizobium radiobacter (see paper)
noxB / CAA82962.1 NoxB from Agrobacterium tumefaciens (see 3 papers)
    24% identity, 86% coverage of query (60.8 bits)

SOX_HUMAN / Q9P0Z9 Peroxisomal sarcosine oxidase; PSO; L-pipecolate oxidase; L-pipecolic acid oxidase; EC 1.5.3.1; EC 1.5.3.7 from Homo sapiens (Human) (see paper)
Q9P0Z9 L-pipecolate oxidase (EC 1.5.3.7) from Homo sapiens (see paper)
    23% identity, 96% coverage of query (60.8 bits)

7fgpA / A0A1M6P181 Crystal structure of aureimonas altamirenisis flavin-containing opine dehydrogenase (fad-bound form)
    26% identity, 99% coverage of query (58.9 bits)

dmg1 / Q9AGP8 dimethylglycine oxidase (EC 1.5.3.10) from Arthrobacter globiformis (see 7 papers)
DMGO_ARTGO / Q9AGP8 Dimethylglycine oxidase; DMGO; EC 1.5.3.10 from Arthrobacter globiformis (see 4 papers)
Q9AGP8 dimethylglycine oxidase (EC 1.5.3.10) from Arthrobacter globiformis (see paper)
    25% identity, 86% coverage of query (57.0 bits)

1pj6A / Q9AGP8 Crystal structure of dimethylglycine oxidase of arthrobacter globiformis in complex with folic acid (see paper)
    25% identity, 86% coverage of query (56.6 bits)

1pj7A Structure of dimethylglycine oxidase of arthrobacter globiformis in complex with folinic acid
    25% identity, 86% coverage of query (56.6 bits)

3gsiA Crystal structure of d552a dimethylglycine oxidase mutant of arthrobacter globiformis in complex with tetrahydrofolate
    25% identity, 86% coverage of query (56.6 bits)

5ez7A / Q9HUH4 Crystal structure of the fad dependent oxidoreductase pa4991 from pseudomonas aeruginosa (see paper)
    30% identity, 82% coverage of query (50.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory