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Searching for up to 100 curated homologs for GFF3313 FitnessBrowser__Phaeo:GFF3313 (604 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 2.A.15.1.6 / D0U567 The glycine betaine, dimethylsulfoniopropionate:Na+ symporter from Psychrobacter sp. J466 (see paper)
    45% identity, 99% coverage of query (465 bits)

BETL_LISMN / Q9X4A5 Glycine betaine transporter BetL; Glycine betaine-Na(+) symporter from Listeria monocytogenes (see 4 papers)
TC 2.A.15.1.11 / Q9X4A5 Glycine betaine transporter BetL (Glycine betaine-Na(+) symporter) from Listeria monocytogenes (see 4 papers)
    32% identity, 93% coverage of query (276 bits)

GBTR_ACIAD / Q6F754 Glycine betaine transporter from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
TC 2.A.15.1.9 / Q6F754 High affinity glycine betaine uptake system from Acinetobacter sp. (strain ADP1) (see paper)
    33% identity, 96% coverage of query (266 bits)

BCCT1_VIBPA / Q87PP5 Glycine betaine/proline/choline/ectoine transporter VP1456 from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) (see paper)
    31% identity, 96% coverage of query (258 bits)

OPUD_BACSU / P54417 Glycine betaine transporter OpuD from Bacillus subtilis (strain 168) (see paper)
TC 2.A.15.1.1 / P54417 Glycine betaine:Na+ symporter (also transports dimethylsulfonioacetate and dimethylsulfoniopropionate) from Bacillus subtilis (see 3 papers)
    30% identity, 93% coverage of query (254 bits)

BETS_RHIML / G3XCN6 Glycine betaine/proline betaine transporter BetS from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
TC 2.A.15.1.5 / Q92WM0 Glycine-betaine/proline-betaine:Na+ symporter, BetS; BetT, OpuD (see 2 papers)
    32% identity, 96% coverage of query (254 bits)

BETT2_ACIAD / Q6FDF5 Osmo-dependent choline transporter BetT2 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
    32% identity, 95% coverage of query (250 bits)

TC 2.A.15.1.3 / Q4ZLW8 Low affinity (0.9 mM), high efficiency, choline/glycine betaine:H+ symporter, BetT from Pseudomonas syringae pv. syringae (strain B728a) (see paper)
    33% identity, 89% coverage of query (248 bits)

ECTP_CORGL / Q79VE0 Ectoine/glycine betaine/proline transporter EctP from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
TC 2.A.15.1.2 / Q79VE0 Ectosine/glycine betaine/proline:Na+ symporter (see 2 papers)
ectP / CAA04760.1 EctP protein from Corynebacterium glutamicum (see paper)
    33% identity, 91% coverage of query (248 bits)

BCCT2_VIBPA / Q87NZ5 Glycine betaine/proline/choline transporter VP1723 from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) (see paper)
    30% identity, 92% coverage of query (229 bits)

Build an alignment

Build an alignment for GFF3313 and 10 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q0PCR9 ABC-type quaternary amine transporter (EC 7.6.2.9) from Aphanothece halophytica (see paper)
    28% identity, 95% coverage of query (225 bits)

LCOP_CORGL / Q8NN75 Betaine/ectoine transporter LcoP; Low capacity osmoregulated permease from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
TC 2.A.15.1.7 / Q8NN75 The ectoine/glycine:Na+ symporter, LcoP from Corynebacterium glutamicum (see paper)
    30% identity, 84% coverage of query (198 bits)

BCCT4_VIBPA / Q87J97 Glycine betaine transporter 2 from Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) (see paper)
    28% identity, 82% coverage of query (150 bits)

CARNT_ACIB2 / D0C9N4 Carnitine transporter from Acinetobacter baumannii (strain ATCC 19606 / DSM 30007 / JCM 6841 / CCUG 19606 / CIP 70.34 / NBRC 109757 / NCIMB 12457 / NCTC 12156 / 81) (see paper)
    25% identity, 84% coverage of query (114 bits)

CAIT_PROMH / B4EY22 L-carnitine/gamma-butyrobetaine antiporter from Proteus mirabilis (strain HI4320) (see 2 papers)
TC 2.A.15.2.2 / B4EY22 The L-carnitine:γ-butyrobetaine antiporter, CaiT from Proteus mirabilis (strain HI4320) (see 2 papers)
    26% identity, 91% coverage of query (113 bits)

2wswA / B4EY22 Crystal structure of carnitine transporter from proteus mirabilis (see paper)
    25% identity, 91% coverage of query (109 bits)

4m8jA Crystal structure of cait r262e bound to gamma-butyrobetaine
    25% identity, 91% coverage of query (109 bits)

YaaP / b0040 L-carnitine:γ-butyrobetaine antiporter from Escherichia coli K-12 substr. MG1655 (see paper)
caiT / P31553 L-carnitine:γ-butyrobetaine antiporter from Escherichia coli (strain K12) (see 4 papers)
CAIT_ECOLI / P31553 L-carnitine/gamma-butyrobetaine antiporter from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.15.2.1 / P31553 Carnitine:γ-butyrobetaine antiporter from Escherichia coli (see 7 papers)
    25% identity, 91% coverage of query (103 bits)

3hfxA Crystal structure of carnitine transporter
    25% identity, 91% coverage of query (103 bits)

2wsxA / P31553 Crystal structure of carnitine transporter from escherichia coli (see paper)
    25% identity, 91% coverage of query (99.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory