Searching for up to 100 curated homologs for GFF3437 FitnessBrowser__Phaeo:GFF3437 (408 a.a.)
Found high-coverage hits (≥70%) to 94 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
CA265_RS15860 threonine deaminase (EC 4.3.1.19) from Pedobacter sp. GW460-11-11-14-LB5
47% identity, 100% coverage of query (381 bits)
ilvA / AAA96639.1 threonine dehydratase from Bacillus subtilis (see 3 papers)
45% identity, 98% coverage of query (338 bits)
Q04513 threonine ammonia-lyase (EC 4.3.1.19) from Corynebacterium glutamicum (see paper)
43% identity, 96% coverage of query (300 bits)
A0QX60 threonine ammonia-lyase (EC 4.3.1.19) from Mycolicibacterium smegmatis (see paper)
44% identity, 92% coverage of query (296 bits)
TD_NICAT / Q9AXU4 Threonine dehydratase; Threonine deaminase; EC 4.3.1.19 from Nicotiana attenuata (Coyote tobacco) (see 2 papers)
Q9AXU4 threonine ammonia-lyase (EC 4.3.1.19) from Nicotiana attenuata (see paper)
38% identity, 87% coverage of query (210 bits)
TD1_SOLLC / A0FKE6 Threonine dehydratase 1 biosynthetic, chloroplastic; SlTD1; Threonine deaminase 1; EC 4.3.1.19 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see 2 papers)
37% identity, 93% coverage of query (204 bits)
TD2_SOLLC / P25306 Threonine dehydratase 2 biosynthetic, chloroplastic; SlTD2; Threonine deaminase 2; EC 4.3.1.17; EC 4.3.1.19 from Solanum lycopersicum (Tomato) (Lycopersicon esculentum) (see 5 papers)
33% identity, 93% coverage of query (189 bits)
Ile / b3772 threonine deaminase (EC 4.3.1.19) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ilvA / P04968 threonine deaminase (EC 4.3.1.19) from Escherichia coli (strain K12) (see 21 papers)
ILVA_ECOLI / P04968 L-threonine dehydratase biosynthetic IlvA; Threonine deaminase; EC 4.3.1.19 from Escherichia coli (strain K12) (see 4 papers)
P04968 threonine ammonia-lyase (EC 4.3.1.19) from Escherichia coli (see paper)
34% identity, 98% coverage of query (186 bits)
1tdjA / P04968 Threonine deaminase (biosynthetic) from e. Coli (see paper)
34% identity, 93% coverage of query (184 bits)
V6QU65 threonine ammonia-lyase (EC 4.3.1.19) from Fusarium graminearum (see paper)
34% identity, 93% coverage of query (177 bits)
THDH_SCHPO / O94634 Threonine dehydratase, mitochondrial; Threonine deaminase; EC 4.3.1.19 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
34% identity, 83% coverage of query (174 bits)
ILV1 putative uncharacterized protein ILV1 from Candida albicans (see paper)
32% identity, 93% coverage of query (174 bits)
THDH_YEAST / P00927 Threonine dehydratase, mitochondrial; Threonine deaminase; EC 4.3.1.19 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
32% identity, 94% coverage of query (172 bits)
CH_124219 threonine deaminase [Arxula adeninivorans] from Magnaporthe grisea 70-15 (see paper)
32% identity, 93% coverage of query (162 bits)
ILV / CAA10977.1 threonine deaminase from Blastobotrys adeninivorans (see paper)
31% identity, 93% coverage of query (159 bits)
B1N2N4 L-serine ammonia-lyase (EC 4.3.1.17) from Entamoeba histolytica (see paper)
31% identity, 91% coverage of query (150 bits)
TSAL_GEOSL / Q74FW6 L-threonine ammonia-lyase; L-serine ammonia-lyase; Threonine/serine ammonia-lyase; EC 4.3.1.19; EC 4.3.1.17 from Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) (see paper)
Q74FW6 threonine ammonia-lyase (EC 4.3.1.19) from Geobacter sulfurreducens (see paper)
33% identity, 95% coverage of query (146 bits)
TSAL_THEMA / Q9WYJ1 L-threonine ammonia-lyase; L-serine ammonia-lyase; Threonine dehydratase; EC 4.3.1.19; EC 4.3.1.17 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
33% identity, 94% coverage of query (142 bits)
Ga0059261_3694 threonine deaminase (EC 4.3.1.19) from Sphingomonas koreensis DSMZ 15582
33% identity, 84% coverage of query (136 bits)
2gn2A / P11954 Crystal structure of tetrameric biodegradative threonine deaminase (tdcb) from salmonella typhimurium in complex with cmp at 2.5a resolution (hexagonal form) (see paper)
33% identity, 72% coverage of query (131 bits)
TDCB_SALTY / P11954 L-threonine dehydratase catabolic TdcB; L-serine dehydratase; Threonine deaminase; EC 4.3.1.19; EC 4.3.1.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
33% identity, 72% coverage of query (131 bits)
Tdc / b3117 catabolic threonine dehydratase (EC 4.3.1.17; EC 4.3.1.19) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
tdcB / P0AGF6 catabolic threonine dehydratase (EC 4.3.1.17; EC 4.3.1.19) from Escherichia coli (strain K12) (see 25 papers)
TDCB_ECOLI / P0AGF6 L-threonine dehydratase catabolic TdcB; L-serine dehydratase; Threonine deaminase; EC 4.3.1.19; EC 4.3.1.17 from Escherichia coli (strain K12) (see 4 papers)
tdcB / RF|NP_417587 threonine ammonia-lyase; EC 4.3.1.19 from Escherichia coli K12 (see 7 papers)
33% identity, 75% coverage of query (131 bits)
Q2V0H1 serine racemase (EC 5.1.1.18) from Pyrobaculum islandicum (see paper)
33% identity, 93% coverage of query (130 bits)
CCNA_03750 threonine deaminase (EC 4.3.1.19) from Caulobacter crescentus NA1000
35% identity, 80% coverage of query (129 bits)
Build an alignment for GFF3437 and 24 homologs with ≥ 30% identity
Or download the sequences
SRR_SCHPO / O59791 Serine racemase; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; EC 4.3.1.17; EC 4.3.1.18; EC 5.1.1.18 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 2 papers)
O59791 serine racemase (EC 5.1.1.18) from Schizosaccharomyces pombe (see 2 papers)
27% identity, 74% coverage of query (119 bits)
2zpuA / O59791 Crystal structure of modified serine racemase from s.Pombe. (see paper)
27% identity, 74% coverage of query (119 bits)
1wtcA Crystal structure of s.Pombe serine racemase complex with amppcp
27% identity, 74% coverage of query (119 bits)
1v71A Crystal structure of s.Pombe serine racemase
27% identity, 74% coverage of query (119 bits)
2zr8A Crystal structure of modified serine racemase complexed with serine
27% identity, 74% coverage of query (119 bits)
F7ZG00 serine racemase (EC 5.1.1.18) from Roseobacter litoralis (see paper)
29% identity, 75% coverage of query (116 bits)
thadh / A4F2N8 L-threo-3-hydroxy aspartate ammonia-lyase (EC 4.3.1.16) from Pseudomonas sp. (see 2 papers)
LTHAD_PSESP / A4F2N8 L-threo-3-hydroxyaspartate ammonia-lyase; L-threo-3-hydroxyaspartate dehydratase; L-THA DH; EC 4.3.1.16 from Pseudomonas sp. (see 2 papers)
A4F2N8 threo-3-hydroxy-L-aspartate ammonia-lyase (EC 4.3.1.16) from Pseudomonas sp. T62 (see paper)
29% identity, 76% coverage of query (112 bits)
AKS11_ALTAL / V5Y0V0 Threonine dehydratase-like protein AKTS1-1; AK-toxin biosynthesis protein S1-1; EC 4.3.1.- from Alternaria alternata (Alternaria rot fungus) (Torula alternata) (see 4 papers)
28% identity, 74% coverage of query (112 bits)
BHCB_PARDP / A1B8Z2 beta-hydroxyaspartate dehydratase; EC 4.2.1.- from Paracoccus denitrificans (strain Pd 1222) (see paper)
28% identity, 74% coverage of query (109 bits)
LTHAD_YEAST / P36007 L-threo-3-hydroxyaspartate ammonia-lyase; L-threo-3-hydroxyaspartate dehydratase; EC 4.3.1.16 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
27% identity, 74% coverage of query (107 bits)
L0N5C4 threo-3-hydroxy-L-aspartate ammonia-lyase (EC 4.3.1.16) from Pseudomonas sp. N99 (see paper)
27% identity, 74% coverage of query (107 bits)
Q93968 serine racemase (EC 5.1.1.18) from Caenorhabditis elegans (see paper)
29% identity, 74% coverage of query (106 bits)
K1QH67 aspartate racemase (EC 5.1.1.13) from Crassostrea gigas (see paper)
25% identity, 74% coverage of query (102 bits)
A0A0U5AKI6 serine racemase (EC 5.1.1.18) from Crassostrea gigas (see paper)
28% identity, 71% coverage of query (101 bits)
1pwhA / P09367 Rat liver l-serine dehydratase- complex with pyridoxyl-(o-methyl- serine)-5-monophosphate (see paper)
26% identity, 75% coverage of query (100 bits)
A0QY48 L-serine ammonia-lyase (EC 4.3.1.17) from Mycolicibacterium smegmatis (see paper)
32% identity, 71% coverage of query (100 bits)
Asr / BAE78960.1 aspartate racemase from Scapharca broughtonii (see paper)
27% identity, 71% coverage of query (99.8 bits)
SDSL_MOUSE / Q8R238 Serine dehydratase-like; L-serine deaminase; L-serine dehydratase/L-threonine deaminase; L-threonine dehydratase; TDH; SDH; EC 4.3.1.17; EC 4.3.1.19 from Mus musculus (Mouse) (see paper)
28% identity, 72% coverage of query (98.2 bits)
6zspAAA serine racemase bound to atp and malonate.
28% identity, 70% coverage of query (96.7 bits)
SRR / Q9GZT4 Serine racemase (EC 5.1.1.10) from Homo sapiens (see 4 papers)
SRR_HUMAN / Q9GZT4 Serine racemase; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; EC 5.1.1.18; EC 4.3.1.18; EC 4.3.1.17 from Homo sapiens (Human) (see 3 papers)
27% identity, 73% coverage of query (95.1 bits)
7nbcAAA / Q9GZT4 structure of human serine racemase in complex with DSiP fragment Z2856434779, XChem fragment screen (see paper)
27% identity, 70% coverage of query (95.1 bits)
7nbhAAA structure of human serine racemase in complex with DSiP fragment Z26781964, XChem fragment screen
27% identity, 70% coverage of query (95.1 bits)
3l6bA X-ray crystal structure of human serine racemase in complex with malonate a potent inhibitor
27% identity, 70% coverage of query (95.1 bits)
7nbfAAA structure of human serine racemase in complex with DSiP fragment Z126932614, XChem fragment screen
27% identity, 70% coverage of query (95.1 bits)
7nbdAAA structure of human serine racemase in complex with DSiP fragment Z235449082, XChem fragment screen
27% identity, 70% coverage of query (95.1 bits)
7nbcCCC structure of human serine racemase in complex with DSiP fragment Z2856434779, XChem fragment screen
27% identity, 70% coverage of query (95.1 bits)
7nbgAAA structure of human serine racemase in complex with DSiP fragment Z52314092, XChem fragment screen
27% identity, 70% coverage of query (95.1 bits)
7nbgDDD structure of human serine racemase in complex with DSiP fragment Z52314092, XChem fragment screen
27% identity, 70% coverage of query (94.7 bits)
Q54HH2 D-Serine ammonia-lyase (EC 4.3.1.18) from Dictyostelium discoideum (see paper)
25% identity, 75% coverage of query (94.0 bits)
SRR_ORYSJ / Q7XSN8 Serine racemase; D-serine dehydratase; D-serine ammonia-lyase; L-serine dehydratase; L-serine ammonia-lyase; EC 5.1.1.18; EC 4.3.1.18; EC 4.3.1.17 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
Q7XSN8 serine racemase (EC 5.1.1.18) from Oryza sativa (see paper)
26% identity, 76% coverage of query (92.4 bits)
A0A0U4MRI4 serine racemase (EC 5.1.1.18) from Penaeus monodon (see paper)
26% identity, 76% coverage of query (91.7 bits)
sr / Q2PGG3 serine racemase/D-serine ammonia-lyase (EC 5.1.1.10) from Arabidopsis thaliana (see paper)
SRR_ARATH / Q2PGG3 Serine racemase; AtSR; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; EC 4.3.1.17; EC 4.3.1.18; EC 5.1.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q2PGG3 serine racemase (EC 5.1.1.18) from Arabidopsis thaliana (see paper)
28% identity, 71% coverage of query (86.3 bits)
SDS / P20132 L-serine dehydratase (EC 4.3.1.19; EC 4.3.1.17) from Homo sapiens (see 2 papers)
SDHL_HUMAN / P20132 L-serine dehydratase/L-threonine deaminase; SDH; L-serine deaminase; L-threonine dehydratase; TDH; EC 4.3.1.17; EC 4.3.1.19 from Homo sapiens (Human) (see 2 papers)
P20132 L-serine ammonia-lyase (EC 4.3.1.17) from Homo sapiens (see 3 papers)
29% identity, 73% coverage of query (86.3 bits)
CYSK_EMENI / P50867 Cysteine synthase 1; CS 1; O-acetylserine (thiol)-lyase 1; OAS-TL 1; O-acetylserine sulfhydrylase 1; O-succinylserine sulfhydrylase; EC 2.5.1.-; EC 2.5.1.47 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
cysB / GB|AAC06128.1 cysteine synthase; EC 2.5.1.47 from Emericella nidulans (see 3 papers)
26% identity, 74% coverage of query (84.7 bits)
F5CAQ9 serine racemase (EC 5.1.1.18) from Zea mays (see paper)
27% identity, 75% coverage of query (84.3 bits)
sr / A5HUN0 serine racemase/D-serine ammonia-lyase (EC 5.1.1.10) from Hordeum vulgare (see paper)
A5HUN0 serine racemase (EC 5.1.1.18) from Hordeum vulgare (see paper)
27% identity, 71% coverage of query (84.3 bits)
A0A0U5A554 aspartate racemase (EC 5.1.1.13) from Penaeus monodon (see paper)
27% identity, 75% coverage of query (84.3 bits)
5cvcA / F5CAQ9 Structure of maize serine racemase (see paper)
27% identity, 75% coverage of query (84.0 bits)
cysB / AAC06128.1 cysteine synthase from Aspergillus nidulans (see paper)
27% identity, 70% coverage of query (84.0 bits)
1ve5A / Q5SLL4 Crystal structure of t.Th. Hb8 threonine deaminase
29% identity, 72% coverage of query (83.6 bits)
1p5jA / P20132 Crystal structure analysis of human serine dehydratase (see paper)
29% identity, 73% coverage of query (82.8 bits)
CYSK_NEUCR / Q7RYW6 Cysteine synthase 1; CS 1; O-acetylserine (thiol)-lyase 1; OAS-TL 1; O-acetylserine sulfhydrylase 1; O-succinylserine sulfhydrylase; EC 2.5.1.-; EC 2.5.1.47 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see paper)
26% identity, 80% coverage of query (78.6 bits)
SRR_RAT / Q76EQ0 Serine racemase; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; EC 5.1.1.18; EC 4.3.1.18; EC 4.3.1.17 from Rattus norvegicus (Rat) (see 2 papers)
Q76EQ0 serine racemase (EC 5.1.1.18) from Rattus norvegicus (see 6 papers)
27% identity, 72% coverage of query (76.3 bits)
1ve5D / Q5SLL4 Crystal structure of t.Th. Hb8 threonine deaminase
28% identity, 72% coverage of query (73.9 bits)
3hmkA Crystal structure of serine racemase
27% identity, 71% coverage of query (73.6 bits)
SRR_MOUSE / Q9QZX7 Serine racemase; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; EC 5.1.1.18; EC 4.3.1.18; EC 4.3.1.17 from Mus musculus (Mouse) (see 5 papers)
27% identity, 71% coverage of query (71.6 bits)
A0A0X1KHE6 L-serine ammonia-lyase (EC 4.3.1.17) from Rhizomucor miehei (see paper)
26% identity, 75% coverage of query (69.7 bits)
5c3uA / A0A0X1KHE6 Crystal structure of a fungal l-serine ammonia-lyase from rhizomucor miehei (see paper)
26% identity, 75% coverage of query (68.9 bits)
CYSK_SCHPO / O59701 Cysteine synthase 1; CS 1; O-acetylserine (thiol)-lyase 1; OAS-TL 1; O-acetylserine sulfhydrylase 1; O-succinylserine sulfhydrylase; EC 2.5.1.-; EC 2.5.1.47 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see 3 papers)
cys11 / RF|NP_595332.1 cysteine synthase from Schizosaccharomyces pombe (see 2 papers)
25% identity, 73% coverage of query (68.6 bits)
trpB1 / P50909 β subunit of tryptophan synthase (EC 4.2.1.122) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
P50909 tryptophan synthase (EC 4.2.1.20) from Thermotoga maritima (see paper)
27% identity, 73% coverage of query (65.9 bits)
A0A2U8JPY3 tryptophan synthase (indole-salvaging) (EC 4.2.1.122); tryptophan synthase (EC 4.2.1.20) from Psilocybe cubensis (see paper)
26% identity, 77% coverage of query (62.4 bits)
8egzB / P50909 Engineered tyrosine synthase (tmtyrs1) derived from t. Maritima trpb with ser bound as the amino-acrylate intermediate
26% identity, 73% coverage of query (61.2 bits)
8eh0A Engineered tyrosine synthase (tmtyrs1) derived from t. Maritima trpb with ser bound as the amino-acrylate intermediate and complexed with quinoline n-oxide
26% identity, 73% coverage of query (61.2 bits)
8egyA Engineered holo tyrosine synthase (tmtyrs1) derived from t. Maritima trpb
26% identity, 73% coverage of query (61.2 bits)
3aeyA Apo form of threonine synthase from thermus thermophilus hb8
26% identity, 70% coverage of query (58.5 bits)
P83823 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see paper)
Q5SL02 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see 2 papers)
3aexA / Q5SL02 Catalytic intermediate analogue of threonine synthase from thermus thermophilus hb8 (see paper)
26% identity, 70% coverage of query (58.5 bits)
1v7cA Crystal structure of threonine synthase from thermus thermophilus hb8 in complex with a substrate analogue
26% identity, 70% coverage of query (58.5 bits)
1uimA Crystal structure of threonine synthase from thermus thermophilus hb8, orthorhombic crystal form
26% identity, 70% coverage of query (58.2 bits)
8eh1A Engineered tyrosine synthase (tmtyrs1) derived from t. Maritima trpb with ser bound as the amino-acrylate intermediate and complexed with 4-hydroxyquinoline
26% identity, 71% coverage of query (57.8 bits)
5vm5D Engineered tryptophan synthase b-subunit from pyrococcus furiosus, pftrpb2b9, with ser bound
26% identity, 71% coverage of query (51.6 bits)
5dw0A Trpb from pyrococcus furiosus with l-serine bound as the external aldimine
24% identity, 72% coverage of query (50.8 bits)
5ixjD / Q8U093 Tryptophan synthase beta-subunit from pyrococcus furiosus with l- threonine non-covalently bound in the active site (see paper)
25% identity, 72% coverage of query (50.8 bits)
7rnpA Engineered tryptophan synthase b-subunit from pyrococcus furiosus, pftrpb2b9_h275e with 4-cl-trp non-covalently bound
24% identity, 71% coverage of query (50.8 bits)
5t6mB Structure of the tryptophan synthase b-subunit from pyroccus furiosus with b-methyltryptophan non-covalently bound
24% identity, 71% coverage of query (50.8 bits)
1v8zA X-ray crystal structure of the tryptophan synthase b2 subunit from hyperthermophile, pyrococcus furiosus
24% identity, 71% coverage of query (50.8 bits)
5t6mA Structure of the tryptophan synthase b-subunit from pyroccus furiosus with b-methyltryptophan non-covalently bound
25% identity, 72% coverage of query (50.4 bits)
6am8B Engineered tryptophan synthase b-subunit from pyrococcus furiosus, pftrpb2b9 with trp bound as e(aex2)
25% identity, 71% coverage of query (50.4 bits)
6cuzA Engineered trpb from pyrococcus furiosus, pftrpb7e6 with (2s,3r)- ethylserine bound as the amino-acrylate
24% identity, 71% coverage of query (50.4 bits)
6cutA Engineered holo trpb from pyrococcus furiosus, pftrpb7e6 with (2s,3s)- isopropylserine bound as the external aldimine
24% identity, 71% coverage of query (50.4 bits)
5dw3A Tryptophan synthase beta-subunit from pyrococcus furiosus with product l-tryptophan non-covalently bound in the active site
24% identity, 72% coverage of query (49.7 bits)
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