Searching for up to 100 curated homologs for GFF3533 FitnessBrowser__WCS417:GFF3533 (322 a.a.)
Found high-coverage hits (≥70%) to 26 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.14.8 / Q8GRB1 PvuD, component of The iron-vibrioferrin uptake porter from Vibrio parahaemolyticus (see paper)
45% identity, 98% coverage of query (234 bits)
FecD / b4288 ferric citrate ABC transporter membrane subunit FecD (EC 7.2.2.18) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FecD / P15029 ferric citrate ABC transporter membrane subunit FecD (EC 7.2.2.18) from Escherichia coli (strain K12) (see paper)
FECD_ECOLI / P15029 Fe(3+) dicitrate transport system permease protein FecD; Iron(III) dicitrate transport system permease protein FecD from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.14.1 / P15029 FecD aka B4288, component of Iron (Fe3+) or ferric-dicitrate porter from Escherichia coli (see 5 papers)
fecD / GB|AAC77244.1 iron(III) dicitrate transport system permease protein FecD from Escherichia coli K12 (see 6 papers)
46% identity, 94% coverage of query (230 bits)
YFHA_BACSU / O31569 Probable siderophore transport system permease protein YfhA from Bacillus subtilis (strain 168) (see 2 papers)
39% identity, 97% coverage of query (196 bits)
FPUB_BACAN / Q81L64 Petrobactin import system permease protein FpuB from Bacillus anthracis (see paper)
40% identity, 85% coverage of query (195 bits)
FEUC_BACSU / P40411 Iron-uptake system permease protein FeuC from Bacillus subtilis (strain 168) (see 2 papers)
TC 3.A.1.14.15 / P40411 Iron-uptake system permease protein feuC, component of Uptake transporter for the catecholic trilactone (2, 3-dihydroxybenzoate-glycine-threonine)3 siderophore bacillibactin (for ferric iron scavenging), FeuABC from Bacillus subtilis (see 5 papers)
34% identity, 97% coverage of query (177 bits)
TC 3.A.1.14.5 / Q56992 HmuU aka YPO0280 aka Y0540, component of Heme (hemin) uptake porter. The receptor, HmuT, binds two parallel stacked heme molecules, and two are transported per reaction cycle from Yersinia pestis (see 4 papers)
39% identity, 93% coverage of query (175 bits)
TC 3.A.1.14.16 / A8GDS7 HemU, component of The heme-specific uptake porter, HemTUV from Serratia proteamaculans (strain 568)
38% identity, 93% coverage of query (173 bits)
fhuG / GI|2832797 ferrichrome transport system permease protein FhuG from Bacillus subtilis (see paper)
34% identity, 99% coverage of query (164 bits)
TC 3.A.1.14.18 / Q32AY2 Putative permease of iron compound ABC transport system, component of The heme uptake porter, ShuTUV (Burkhard and Wilks, 2008). Transports a single heme per reaction cycle (Mattle et al., 2010). (3-d structure of ShuT is known (2RG7) from Shigella dysenteriae serotype 1 (strain Sd197) (see paper)
37% identity, 85% coverage of query (164 bits)
feuC / GI|1256154 iron-uptake system permease protein FeuC from Bacillus subtilis (see 5 papers)
33% identity, 91% coverage of query (154 bits)
TC 3.A.1.14.12 / Q9L179 DesB, component of Desferrioxamine B uptake porter, DesABC from Streptomyces coelicolor (see paper)
41% identity, 85% coverage of query (148 bits)
hmuU / CAC34394.1 HmuU protein from Rhizobium leguminosarum (see paper)
35% identity, 85% coverage of query (147 bits)
TC 3.A.1.14.10 / Q99YA3 Ferrichrome transport system permease protein, component of The heme porter, Shp/SiaABC (HtsABC). Shp is a cell surface heme binding protein that transfers the heme directly to HstA (Nygaard et al., 2006). The crystal structure of the heme binding domain of Shp has been solved (Aranda et al., 2007). HtsABC is required for the uptake of staphyloferrin A (Beasley et al. 2009). The Shp cell surface heme receptor feeds iron-heme to the transporter in preparation for uptake from Streptococcus pyogenes serotype M1 (see 2 papers)
33% identity, 93% coverage of query (142 bits)
FEUB_BACSU / P40410 Iron-uptake system permease protein FeuB from Bacillus subtilis (strain 168) (see 4 papers)
TC 3.A.1.14.15 / P40410 Iron-uptake system permease protein feuB, component of Uptake transporter for the catecholic trilactone (2, 3-dihydroxybenzoate-glycine-threonine)3 siderophore bacillibactin (for ferric iron scavenging), FeuABC from Bacillus subtilis (see 4 papers)
feuB / GB|BAA19495.1 iron-uptake system permease protein feuB from Bacillus subtilis (see 4 papers)
32% identity, 92% coverage of query (142 bits)
TC 3.A.1.14.4 / Q47085 CbrB, component of Iron-chrysobactine porter from Erwinia chrysanthemi (see paper)
37% identity, 95% coverage of query (141 bits)
ISDF_STAAW / Q8NX64 Probable heme-iron transport system permease protein IsdF; Iron-regulated surface determinant protein F; Staphylococcal iron-regulated protein G from Staphylococcus aureus (strain MW2) (see paper)
34% identity, 93% coverage of query (139 bits)
TC 3.A.1.14.17 / Q7A651 IsdF, component of Heme acquisition ABC uptake transporter, IsdDEF from Staphylococcus aureus (strain N315) (see paper)
34% identity, 93% coverage of query (139 bits)
YFIZ_BACSU / O31568 Probable siderophore transport system permease protein YfiZ from Bacillus subtilis (strain 168) (see 2 papers)
34% identity, 84% coverage of query (139 bits)
TC 3.A.1.14.14 / Q06A41 FtsD, component of The Fe3+ /Fe3+ferrichrome/Fe3+heme uptake porter; SiuABDG (FTSABCD) from Streptococcus pyogenes
36% identity, 99% coverage of query (136 bits)
Build an alignment for GFF3533 and 19 homologs with ≥ 30% identity
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TC 3.A.1.14.7 / Q9X664 FhuB, component of Iron (Fe3+)-hydroxamate porter (transports Fe3+-ferrichrome and Fe3+-ferrioxamine B with FhuD1, and these compounds plus aerobactin and coprogen with FhuD2) from Staphylococcus aureus (see 2 papers)
29% identity, 95% coverage of query (136 bits)
BTUCA_HALSA / Q9HQ19 Cobalamin import system permease protein BtuC from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium) (see paper)
TC 3.A.1.14.9 / Q9HQ19 Iron (III) ABC transporter permease, component of The Corrinoid porter, BtuCDE from Halobacterium salinarium (Halobacterium halobium) (see paper)
38% identity, 82% coverage of query (135 bits)
ISDF_STAA8 / Q2FZE5 Probable heme-iron transport system permease protein IsdF; Iron-regulated surface determinant protein F; Staphylococcal iron-regulated protein G from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see paper)
33% identity, 93% coverage of query (132 bits)
FHUB_BACSU / P49936 Iron(3+)-hydroxamate import system permease protein FhuB; Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein FhuB; Iron(III)-hydroxamate import system permease protein FhuB from Bacillus subtilis (strain 168) (see paper)
fhuB / GI|2832796 ferrichrome transport system permease protein FhuB from Bacillus subtilis (see paper)
33% identity, 84% coverage of query (130 bits)
FecC / b4289 ferric citrate ABC transporter membrane subunit FecC (EC 7.2.2.18) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
FecC / P15030 ferric citrate ABC transporter membrane subunit FecC (EC 7.2.2.18) from Escherichia coli (strain K12) (see paper)
FECC_ECOLI / P15030 Fe(3+) dicitrate transport system permease protein FecC; Iron(III) dicitrate transport system permease protein FecC from Escherichia coli (strain K12) (see 4 papers)
TC 3.A.1.14.1 / P15030 FecC aka B4289, component of Iron (Fe3+) or ferric-dicitrate porter from Escherichia coli (see 5 papers)
38% identity, 84% coverage of query (127 bits)
FhuB / b0153 iron(III) hydroxamate ABC transporter membrane subunit (EC 7.2.2.16) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
FhuB / P06972 iron(III) hydroxamate ABC transporter membrane subunit (EC 7.2.2.16) from Escherichia coli (strain K12) (see 2 papers)
FHUB_ECOLI / P06972 Iron(3+)-hydroxamate import system permease protein FhuB; Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein FhuB; Ferrichrome uptake protein FhuB; Iron(III)-hydroxamate import system permease protein FhuB from Escherichia coli (strain K12) (see 7 papers)
TC 3.A.1.14.3 / P06972 FhuB aka B0153, component of Iron (Fe3+)-hydroxamate (ferrichrome, coprogen, aerobactin, ferrioxamine B, schizakinen, rhodotorulic acid) porter, albomycin porter from Escherichia coli (see 7 papers)
33% identity, 87% coverage of query (120 bits)
5b57A / B4EKB4 Inward-facing conformation of abc heme importer bhuuv from burkholderia cenocepacia (see paper)
37% identity, 84% coverage of query (85.9 bits)
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Lawrence Berkeley National Laboratory