Searching for up to 100 curated homologs for GFF3577 FitnessBrowser__Phaeo:GFF3577 (559 a.a.)

Found high-coverage hits (≥70%) to 24 curated proteins.

Removed hits that are identical to the query, leaving 23

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SM_b21163 Urocanate hydratase (EC 4.2.1.49) from Sinorhizobium meliloti 1021
    84% identity, 100% coverage of query (960 bits)

Ga0059261_3961 Urocanate hydratase (EC 4.2.1.49) from Sphingomonas koreensis DSMZ 15582
    76% identity, 100% coverage of query (889 bits)

AO356_09630 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas fluorescens FW300-N2C3
    76% identity, 98% coverage of query (878 bits)

Pf1N1B4_1587 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas fluorescens FW300-N1B4
    76% identity, 98% coverage of query (877 bits)

Pf6N2E2_3805 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas fluorescens FW300-N2E2
    76% identity, 98% coverage of query (877 bits)

PfGW456L13_326 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas fluorescens GW456-L13
    75% identity, 99% coverage of query (873 bits)

AO353_12250 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas fluorescens FW300-N2E3
    75% identity, 98% coverage of query (872 bits)

hutU / P25080 urocanase subunit (EC 4.2.1.49) from Pseudomonas putida (see 4 papers)
HUTU_PSEPU / P25080 Urocanate hydratase; Urocanase; Imidazolonepropionate hydrolase; EC 4.2.1.49 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
    75% identity, 98% coverage of query (870 bits)

PS417_01720 Urocanate hydratase (EC 4.2.1.49) from Pseudomonas simiae WCS417
    74% identity, 100% coverage of query (869 bits)

1uwkA / P25080 The high resolution structure of urocanate hydratase from pseudomonas putida in complex with urocanate (see paper)
    75% identity, 98% coverage of query (865 bits)

BWI76_RS08735 Urocanate hydratase (EC 4.2.1.49) from Klebsiella michiganensis M5al
    73% identity, 100% coverage of query (860 bits)

Ac3H11_2557 Urocanate hydratase (EC 4.2.1.49) from Acidovorax sp. GW101-3H11
    70% identity, 100% coverage of query (839 bits)

7jfzA / Q5ZVR1 Structure of urocanate hydratase from legionella pneumophila bound to NAD
    69% identity, 98% coverage of query (785 bits)

hutU / P25503 HutU (EC 4.2.1.49) from Bacillus subtilis (strain 168) (see 2 papers)
HUTU_BACSU / P25503 Urocanate hydratase; Urocanase; Imidazolonepropionate hydrolase; EC 4.2.1.49 from Bacillus subtilis (strain 168) (see paper)
    62% identity, 99% coverage of query (701 bits)

2fknB / P25503 Crystal structure of urocanase from bacillus subtilis
    63% identity, 97% coverage of query (698 bits)

HUTU_GEOKA / Q5L084 Urocanate hydratase; Urocanase; Imidazolonepropionate hydrolase; EC 4.2.1.49 from Geobacillus kaustophilus (strain HTA426)
    62% identity, 98% coverage of query (694 bits)

1x87A / Q5L084 2.4a x-ray structure of urocanase protein complexed with NAD
    55% identity, 98% coverage of query (570 bits)

7nedA / A0A0Q9KFZ4 Thiourocanate hydratase from paenibacillus sp. Soil724d2 in complex with cofactor NAD+ and urocanate (see paper)
    50% identity, 96% coverage of query (540 bits)

8q9vA / A0A6P2DXK2 S-methylthiourocanate hydratase from variovorax sp. Ra8 in complex with NAD+ and imidazolone propionate (see paper)
    48% identity, 98% coverage of query (467 bits)

6uekA / Q4D9S6 Structure of urocanate hydratase from trypanosoma cruzi in complex with NAD+ (see paper)
    38% identity, 96% coverage of query (323 bits)

HUTU_HUMAN / Q96N76 Urocanate hydratase; Urocanase; Imidazolonepropionate hydrolase; EC 4.2.1.49 from Homo sapiens (Human) (see paper)
    34% identity, 95% coverage of query (303 bits)

Sama_1632 Urocanate hydratase (EC 4.2.1.49) from Shewanella amazonensis SB2B
    35% identity, 96% coverage of query (298 bits)

6uekD / Q4D9S6 Structure of urocanate hydratase from trypanosoma cruzi in complex with NAD+ (see paper)
    37% identity, 96% coverage of query (290 bits)

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