Searching for up to 100 curated homologs for GFF3596 FitnessBrowser__WCS417:GFF3596 (362 a.a.)
Found high-coverage hits (≥70%) to 55 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ASPQ_PSEFA / O68897 Glutaminase-asparaginase; L-ASNase/L-GLNase; L-asparagine/L-glutamine amidohydrolase; EC 3.5.1.38 from Pseudomonas fluorescens biotype A (see paper)
97% identity, 100% coverage of query (677 bits)
6wywA Crystal structure of pseudomonas 7a glutaminase-asparaginase in complex with l-asp at ph 4.5
84% identity, 91% coverage of query (565 bits)
6wyyA Crystal structure of pseudomonas 7a glutaminase-asparaginase in complex with l-glu at ph 6.5
83% identity, 91% coverage of query (561 bits)
1djoA / P10182 Crystal structure of pseudomonas 7a glutaminase-asparaginase with the inhibitor donv covalently bound in the active site (see paper)
87% identity, 91% coverage of query (558 bits)
4pgaA Glutaminase-asparaginase from pseudomonas 7a
87% identity, 91% coverage of query (558 bits)
1djpA Crystal structure of pseudomonas 7a glutaminase-asparaginase with the inhibitor don covalently bound in the active site
87% identity, 91% coverage of query (558 bits)
6wyzA Crystal structure of pseudomonas 7a glutaminase-asparaginase (mutant k173m) in complex with d-glu at ph 5.5
82% identity, 91% coverage of query (553 bits)
ASPQ_PSES7 / P10182 Glutaminase-asparaginase; L-ASNase/L-GLNase; L-asparagine/L-glutamine amidohydrolase; PGA; EC 3.5.1.38 from Pseudomonas sp. (strain ATCC 29598 / 7A) (see paper)
84% identity, 93% coverage of query (547 bits)
ansB / PDB|1AGX_A glutaminase-asparaginase; EC 3.5.1.38 from Acinetobacter glutaminasificans (see 3 papers)
62% identity, 91% coverage of query (414 bits)
ASPG2_BACSU / O34482 L-asparaginase 2; L-ASNase 2; L-asparagine amidohydrolase 2; EC 3.5.1.1 from Bacillus subtilis (strain 168) (see paper)
49% identity, 94% coverage of query (303 bits)
C0KWF5 asparaginase (EC 3.5.1.1) from Escherichia coli (see paper)
49% identity, 91% coverage of query (294 bits)
5k3oA / P50286 Wolinella succinogenes l-asparaginase p121 and l-aspartic acid (see paper)
47% identity, 90% coverage of query (294 bits)
5k45A Wolinella succinogenes l-asparaginase p121 + l-glutamic acid
47% identity, 90% coverage of query (294 bits)
AnsB / b2957 L-asparaginase 2 (EC 3.5.1.38; EC 3.5.1.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ansB / P00805 L-asparaginase 2 (EC 3.5.1.38) from Escherichia coli (strain K12) (see 73 papers)
ASPG2_ECOLI / P00805 L-asparaginase 2; L-asparaginase II; L-ASNase II; L-asparagine amidohydrolase II; Colaspase; EC 3.5.1.1 from Escherichia coli (strain K12) (see 5 papers)
49% identity, 91% coverage of query (291 bits)
P50286 asparaginase (EC 3.5.1.1) from Wolinella succinogenes (see paper)
47% identity, 90% coverage of query (290 bits)
1ho3A Crystal structure analysis of e. Coli l-asparaginase ii (y25f mutant)
49% identity, 91% coverage of query (290 bits)
7r5qA Escherichia coli type ii asparaginase n24s mutant in complex with glu
46% identity, 91% coverage of query (286 bits)
1jazA Crystal structure of monoclinic form of d90e mutant of escherichia coli asparaginase ii
46% identity, 91% coverage of query (286 bits)
ansB1 / Q6Q4F4 L-asparaginase subunit (EC 3.5.1.38) from Pectobacterium atrosepticum (see 10 papers)
Q6Q4F4 asparaginase (EC 3.5.1.1) from Pectobacterium atrosepticum (see paper)
45% identity, 97% coverage of query (285 bits)
2gvnA / I1SBD9 L-asparaginase from erwinia carotovora in complex with aspartic acid (see paper)
47% identity, 91% coverage of query (283 bits)
ASPG_DICCH / P06608 L-asparaginase; L-ASNase; L-asparagine amidohydrolase; EC 3.5.1.1 from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see 3 papers)
45% identity, 91% coverage of query (281 bits)
6pa3A / P00805 E. Coli l-asparaginase ii double mutant (t89v,k162t) in complex with l-asn at ph 7.0 (see paper)
48% identity, 91% coverage of query (280 bits)
1hg0A X-ray structure of the complex between erwinia chrysanthemi l- asparaginase and succinic acid
44% identity, 91% coverage of query (279 bits)
2wltA / Q9ZLB9 The crystal structure of helicobacter pylori l-asparaginase at 1.4 a resolution (see paper)
44% identity, 91% coverage of query (278 bits)
1jsrA Crystal structure of erwinia chrysanthemi l-asparaginase complexed with 6-hydroxy-l-norleucine
44% identity, 91% coverage of query (277 bits)
1jslA Crystal structure of erwinia chrysanthemi l-asparaginase complexed with 6-hydroxy-d-norleucine
44% identity, 91% coverage of query (277 bits)
7u6mC / P06608 Albumin binding domain fused to a mutant of the erwinia asparaginase (see paper)
44% identity, 92% coverage of query (276 bits)
Q66CJ2 asparaginase (EC 3.5.1.1) from Yersinia pseudotuberculosis (see 2 papers)
46% identity, 86% coverage of query (275 bits)
Q9ZLB9 asparaginase (EC 3.5.1.1) from Helicobacter pylori J99 (see paper)
43% identity, 91% coverage of query (273 bits)
fraE / Q8ZLD3 N-(1-deoxy-D-fructos-1-yl)-L-asparaginase (EC 3.5.1.1) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
45% identity, 93% coverage of query (272 bits)
Q6Q4F3 asparaginase (EC 3.5.1.1) from Dickeya chrysanthemi (see 2 papers)
45% identity, 91% coverage of query (272 bits)
2hlnA L-asparaginase from erwinia carotovora in complex with glutamic acid
45% identity, 91% coverage of query (265 bits)
B6ZCD8 asparaginase (EC 3.5.1.1) from Helicobacter pylori (see paper)
I0ZIE0 asparaginase (EC 3.5.1.1) from Helicobacter pylori (see paper)
44% identity, 91% coverage of query (264 bits)
BPHYT_RS08815 L-asparaginase (EC 3.5.1.1) from Burkholderia phytofirmans PsJN
46% identity, 91% coverage of query (263 bits)
A0A2X5A091 asparaginase (EC 3.5.1.1); glutaminase (EC 3.5.1.2) from Helicobacter pylori (see paper)
43% identity, 91% coverage of query (261 bits)
1hfwA X-ray structure of the complex between erwinia chrysanthemi l-asparaginase and l-glutamate
43% identity, 91% coverage of query (257 bits)
1hg1A X-ray structure of the complex between erwinia chrysanthemi l-asparaginase and d-aspartate
43% identity, 91% coverage of query (255 bits)
ASP22_YEAST / P0CX77 L-asparaginase 2-2; L-asparaginase II; L-asparagine amidohydrolase II; ASP II; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
ASP23_YEAST / P0CX78 L-asparaginase 2-3; L-asparaginase II; L-asparagine amidohydrolase II; ASP II; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
ASP24_YEAST / P0CX79 L-asparaginase 2-4; L-asparaginase II; L-asparagine amidohydrolase II; ASP II; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
ASP21_YEAST / P0CZ17 L-asparaginase 2-1; L-asparaginase II; L-asparagine amidohydrolase II; ASP II; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
P0CZ17 asparaginase (EC 3.5.1.1) from Saccharomyces cerevisiae (see paper)
36% identity, 91% coverage of query (184 bits)
P38986 asparaginase (EC 3.5.1.1) from Saccharomyces cerevisiae (see paper)
34% identity, 90% coverage of query (171 bits)
P38986 L-asparaginase 1; L-asparaginase I; L-asparagine amidohydrolase I; ASP I; EC 3.5.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
34% identity, 90% coverage of query (171 bits)
Build an alignment for GFF3596 and 40 homologs with ≥ 30% identity
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8h4aB / A0A6I7U6Y2 Blasnase-t13a/m57p
29% identity, 90% coverage of query (125 bits)
7cbuA Blasnase-t13a with l-asp
29% identity, 87% coverage of query (124 bits)
7c8xA Blasnase-t13a with l-asn
30% identity, 87% coverage of query (124 bits)
7c8qA Blasnase-t13a with d-asn
30% identity, 87% coverage of query (124 bits)
J9H7D1 asparaginase (EC 3.5.1.1) from Staphylococcus sp. (see paper)
28% identity, 90% coverage of query (123 bits)
1zq1A / Q9V0T9 Structure of gatde tRNA-dependent amidotransferase from pyrococcus abyssi (see paper)
28% identity, 92% coverage of query (106 bits)
gatD / O26802 glutamyl-tRNA(Gln) amidotransferase subunit D (EC 6.3.5.7) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see paper)
27% identity, 93% coverage of query (90.9 bits)
ASPG_MYCTU / P9WPX5 L-asparaginase; L-ASNase; L-asparagine amidohydrolase; EC 3.5.1.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
31% identity, 77% coverage of query (74.3 bits)
4q0mA / Q8TZE8 Crystal structure of pyrococcus furiosus l-asparaginase (see paper)
26% identity, 73% coverage of query (70.9 bits)
ASPG_PYRFU / Q8TZE8 L-asparaginase; EC 3.5.1.1 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see 5 papers)
Q8TZE8 asparaginase (EC 3.5.1.1) from Pyrococcus furiosus (see 2 papers)
26% identity, 72% coverage of query (70.9 bits)
CA265_RS25090 L-asparaginase (EC 3.5.1.1) from Pedobacter sp. GW460-11-11-14-LB5
26% identity, 79% coverage of query (61.6 bits)
PfGW456L13_740 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens GW456-L13
23% identity, 77% coverage of query (51.2 bits)
Pf6N2E2_4087 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N2E2
23% identity, 77% coverage of query (49.3 bits)
AO356_11100 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N2C3
23% identity, 77% coverage of query (48.9 bits)
Pf1N1B4_2023 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N1B4
23% identity, 77% coverage of query (48.9 bits)
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Lawrence Berkeley National Laboratory