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Searching for up to 100 curated homologs for GFF362 Psest_0363 tripartite ATP-independent periplasmic transporter solute receptor, DctP family (323 a.a.)

Found high-coverage hits (≥70%) to 83 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PP_1169 D-glucuronate / D-galacturonate TRAP transporter, solute receptor component from Pseudomonas putida KT2440
    78% identity, 100% coverage of query (531 bits)

4xfeA / I3UZ52 Crystal structure of a trap periplasmic solute binding protein from pseudomonas putida f1 (pput_1203), target efi-500184, with bound d- glucuronate
    79% identity, 93% coverage of query (501 bits)

4x04A / A8AR30 Crystal structure of a trap periplasmic solute binding protein from citrobacter koseri (cko_04899, target efi-510094) with bound d- glucuronate
    50% identity, 92% coverage of query (314 bits)

4x8rA / A3PLM5 Crystal structure of a trap periplasmic solute binding protein from rhodobacter sphaeroides (rsph17029_2138, target efi-510205) with bound glucuronate
    42% identity, 93% coverage of query (270 bits)

4n8yA / A5E8D2 Crystal structure of a trap periplasmic solute binding protein from bradyrhizobium sp. Btai1 b (bbta_0128), target efi-510056 (bbta_0128), complex with alpha/beta-d-galacturonate (see paper)
    43% identity, 91% coverage of query (251 bits)

4ovrA / A7IKQ4 Crystal structure of a trap periplasmic solute binding protein from xanthobacter autotrophicus py2, target efi-510329, with bound beta-d- galacturonate (see paper)
    42% identity, 90% coverage of query (248 bits)

DCTP_CHRSD / Q1QUN2 Solute-binding protein Csal_2479 from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
    36% identity, 96% coverage of query (236 bits)

DCTP1_POLSJ / Q128M1 Solute-binding protein Bpro_3107 from Polaromonas sp. (strain JS666 / ATCC BAA-500) (see paper)
    42% identity, 89% coverage of query (233 bits)

4mijA / Q128M1 Crystal structure of a trap periplasmic solute binding protein from polaromonas sp. Js666 (bpro_3107), target efi-510173, with bound alpha/beta d-galacturonate, space group p21 (see paper)
    42% identity, 87% coverage of query (232 bits)

4p3lA / Q1QUN2 Crystal structure of a trap periplasmic solute binding protein from chromohalobacter salexigens dsm 3043 (csal_2479), target efi-510085, with bound glucuronate, spg p6122 (see paper)
    37% identity, 90% coverage of query (232 bits)

4mhfA Crystal structure of a trap periplasmic solute binding protein from polaromonas sp. Js666 (bpro_3107), target efi-510173, with bound alpha/beta d-glucuronate, space group p21
    42% identity, 87% coverage of query (232 bits)

DCTP_BURCM / Q0B2F6 Solute-binding protein Bamb_6123 from Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) (Burkholderia cepacia (strain AMMD)) (see paper)
    36% identity, 99% coverage of query (229 bits)

4pf8A / A3T0C3 Crystal structure of a trap periplasmic solute binding protein from sulfitobacter sp. Nas-14.1 (target efi-510299) with bound beta-d- galacturonate (see paper)
    42% identity, 88% coverage of query (227 bits)

4n15A / Q0B2F6 Crystal structure of a trap periplasmic solute binding protein from burkholderia ambifaria (bam_6123), target efi-510059, with bound beta-d-glucuronate (see paper)
    36% identity, 91% coverage of query (223 bits)

4n17A Crystal structure of a trap periplasmic solute binding protein from burkholderia ambifaria (bam_6123), target efi-510059, with bound beta-d-galacturonate
    36% identity, 91% coverage of query (223 bits)

4ovqA / Q160Z9 Crystal structure of a trap periplasmic solute binding protein from roseobacter denitrificans, target efi-510230, with bound beta-d- glucuronate (see paper)
    42% identity, 90% coverage of query (222 bits)

4pddA / Q12HD7 Crystal structure of a trap periplasmic solute binding protein from polaromonas sp js666 (bpro_0088, target efi-510167) bound to d- erythronate (see paper)
    34% identity, 92% coverage of query (171 bits)

4nq8B / A0A0H3LPK2 Crystal structure of a trap periplasmic solute binding protein from bordetella bronchispeptica (bb3421), target efi-510039, with density modeled as pantoate (see paper)
    35% identity, 91% coverage of query (159 bits)

4pakA / A1WPV4 Crystal structure of a trap periplasmic solute binding protein from verminephrobacter eiseniae ef01-2 (veis_3954, target efi-510324) a nephridial symbiont of the earthworm eisenia foetida, bound to (r)- pantoic acid (see paper)
    35% identity, 88% coverage of query (156 bits)

4p9kA Crystal structure of a trap periplasmic solute binding protein from verminephrobacter eiseniae ef01-2 (veis_3954, target efi-510324) a nephridial symbiont of the earthworm eisenia foetida, bound to d- erythronate with residual density suggestive of superposition with copurified alternative ligand.
    35% identity, 88% coverage of query (156 bits)

DCTP_VEREI / A1WPV4 Solute-binding protein Veis_3954 from Verminephrobacter eiseniae (strain EF01-2) (see paper)
    35% identity, 88% coverage of query (155 bits)

4pdhA / Q12CD8 Crystal structure of a trap periplasmic solute binding protein from polaromonas sp js666 (bpro_1871, target efi-510164) bound to d- erythronate (see paper)
    34% identity, 85% coverage of query (155 bits)

4n91A / C7RDZ3 Crystal structure of a trap periplasmic solute binding protein from anaerococcus prevotii dsm 20548 (apre_1383), target efi-510023, with bound alpha/beta d-glucuronate (see paper)
    30% identity, 92% coverage of query (150 bits)

DCTP_ROSDO / Q16BC9 Solute-binding protein RD1_1052 from Roseobacter denitrificans (strain ATCC 33942 / OCh 114) (Erythrobacter sp. (strain OCh 114)) (Roseobacter denitrificans) (see paper)
    33% identity, 83% coverage of query (142 bits)

4pc9A / Q16BC9 Crystal structure of a trap periplasmic solute binding protein from rosenbacter denitrificans och 114 (rd1_1052, target efi-510238) with bound d-mannonate (see paper)
    33% identity, 83% coverage of query (141 bits)

4o8mA / A6VKP1 Crystal structure of a trap periplasmic solute binding protein actinobacillus succinogenes 130z, target efi-510004, with bound l- galactonate (see paper)
    32% identity, 83% coverage of query (141 bits)

4pcdA Crystal structure of a trap periplasmic solute binding protein from roseobacter denitrificans och 114 (rd1_1052, target efi-510238) with bound l-galactonate
    33% identity, 83% coverage of query (141 bits)

Psest_2125 D-gluconate TRAP transporter, periplasmic component from Pseudomonas stutzeri RCH2
    30% identity, 89% coverage of query (139 bits)

Build an alignment

Build an alignment for GFF362 and 28 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

4magA Crystal structure of the periplasmic sialic acid binding protein from vibrio cholerea (see paper)
    27% identity, 91% coverage of query (138 bits)

SIAP_VIBCH / Q9KR64 Sialic acid-binding periplasmic protein SiaP from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see 2 papers)
TC 2.A.56.1.6 / Q9KR64 C4-dicarboxylate-binding periplasmic protein, component of The Na+-dependent sialic acid uptake porter, SiaPQM. SiaQ and SiaM form a 1:1 stoichiometric complex from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see paper)
    27% identity, 91% coverage of query (138 bits)

7a5qB Crystal structure of vcsiap bound to sialic acid
    27% identity, 91% coverage of query (138 bits)

7a5qA Crystal structure of vcsiap bound to sialic acid
    27% identity, 91% coverage of query (138 bits)

Ac3H11_3226 gluconate TRAP transporter, periplasmic solute-binding component from Acidovorax sp. GW101-3H11
    31% identity, 82% coverage of query (135 bits)

YiaO / b3579 2,3-diketo-L-gulonate:Na+ symporter - periplasmic binding protein from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yiaO / P37676 2,3-diketo-L-gulonate:Na+ symporter - periplasmic binding protein from Escherichia coli (strain K12) (see 5 papers)
YIAO_ECOLI / P37676 2,3-diketo-L-gulonate-binding periplasmic protein YiaO; 2,3-DKG-binding protein; Extracytoplasmic solute receptor protein YiaO from Escherichia coli (strain K12) (see paper)
TC 2.A.56.1.2 / P37676 YiaO, component of The 2,3-diketo-L-gulonate (2,3-DKG) transporter, YiaMNO [2,3-KDG is a breakdown product of L-ascorbate] from Escherichia coli (see 6 papers)
    29% identity, 97% coverage of query (131 bits)

AZOBR_RS15915 gluconate TRAP transporter, periplasmic solute-binding component from Azospirillum brasilense Sp245
    31% identity, 75% coverage of query (129 bits)

4pfbA / Q8RE65 Crystal structure of a trap periplasmic solute binding protein from fusobacterium nucleatun (fn1258, target efi-510120) with bound sn- glycerol-3-phosphate (see paper)
    30% identity, 79% coverage of query (126 bits)

7t3eA / Q6LPV9 Structure of the sialic acid bound tripartite atp-independent periplasmic (trap) periplasmic component siap from photobacterium profundum (see paper)
    27% identity, 85% coverage of query (125 bits)

4ovtA / A6X5V3 Crystal structure of a trap periplasmic solute binding protein from ochrobacterium anthropi (oant_3902), target efi-510153, with bound l- fuconate (see paper)
    33% identity, 90% coverage of query (125 bits)

DCTP_RHOCA / P37735 C4-dicarboxylate-binding periplasmic protein DctP from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (see 3 papers)
TC 2.A.56.1.1 / P37735 DctP, component of Tripartite dicarboxylate:H+ symporter (substrates include: fumarate, D- and L-malate, succinate, succinamide, orotate, iticonate and mesaconate) from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (see paper)
    28% identity, 81% coverage of query (121 bits)

4mnpA / Q8RDN9 Structure of the sialic acid binding protein from fusobacterium nucleatum subsp. Nucleatum atcc 25586 (see paper)
    29% identity, 87% coverage of query (120 bits)

4pbqA Crystal structure of a trap periplasmic solute binding protein from haemophilus influenzae rdaw (hicg_00826, target efi-510123) with bound l-gulonate (see paper)
    29% identity, 81% coverage of query (120 bits)

7bbrA / R4JTF7 Crystal structure of the sugar acid binding protein dctpam from advenella mimigardefordensis strain dpn7t (see paper)
    26% identity, 88% coverage of query (119 bits)

TC 2.A.56.1.9 / R4JTF7 Putative TRAP transporter solute receptor DctP, component of The possible disulfide 3,3'-dithiodipropionic acid (DTDP) tripartite transporter, DctMPQ from Advenella mimigardefordensis DPN7
    26% identity, 88% coverage of query (119 bits)

7bcrA Crystal structure of the sugar acid binding protein dctpam from advenella mimigardefordensis strain dpn7t in complex with galactonate
    26% identity, 88% coverage of query (119 bits)

7bcpA Crystal structure of the sugar acid binding protein dctpam from advenella mimigardefordensis strain dpn7t in complex with gluconate
    26% identity, 88% coverage of query (119 bits)

7bcoA Crystal structure of the sugar acid binding protein dctpam from advenella mimigardefordensis strain dpn7t in complex with d-foconate
    26% identity, 88% coverage of query (119 bits)

7bcnA Crystal structure of the sugar acid binding protein dctpam from advenella mimigardefordensis strain dpn7t in complex with xylonic acid
    26% identity, 88% coverage of query (119 bits)

4p8bA / Q0KC03 Crystal structure of a trap periplasmic solute binding protein from ralstonia eutropha h16 (h16_a1328), target efi-510189, with bound (s)-2-hydroxy-2-methyl-3-oxobutanoate ((s)-2-acetolactate) (see paper)
    30% identity, 83% coverage of query (116 bits)

4oanA / Q2IWM2 Crystal structure of a trap periplasmic solute binding protein from rhodopseudomonas palustris haa2 (rpb_2686), target efi-510221, with density modeled as (s)-2-hydroxy-2-methyl-3-oxobutanoate ((s)-2- acetolactate) (see paper)
    26% identity, 90% coverage of query (111 bits)

4mmpA Structure of sialic acid binding protein from pasturella multocida (see paper)
    29% identity, 83% coverage of query (111 bits)

4xeqB Crystal structure of a trap periplasmic solute binding protein from desulfovibrio vulgaris (deval_0042, target efi-510114) bound to copurified (r)-pantoic acid
    27% identity, 83% coverage of query (110 bits)

4nhbB / B8J100 Crystal structure of a trap periplasmic solute binding protein from desulfovibrio desulfuricans (ddes_1525), target efi-510107, with bound sn-glycerol-3-phosphate (see paper)
    27% identity, 80% coverage of query (107 bits)

SIAP_HAEIN / P44542 Sialic acid-binding periplasmic protein SiaP; Extracytoplasmic solute receptor protein SiaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 4 papers)
TC 2.A.56.1.3 / P44542 SiaP. AKA Sialic acid-binding periplasmic protein, component of Na+-dependent (smf-driven) sialic acid (N-acetyl neuraminic acid) transporter, SiaTP (Allen et al., 2005; Severi et al., 2005; Johnston et al., 2008). SiaT is also called SiaQM from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 4 papers)
    24% identity, 100% coverage of query (103 bits)

DCTP_OLEA2 / Q312S0 Isethionate-binding periplasmic protein DctP; TRAP transporter, DctP solute-binding subunit from Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20) (Desulfovibrio alaskensis) (see paper)
    26% identity, 99% coverage of query (103 bits)

DCTP_VIBCH / Q9KQR9 C4-dicarboxylate-binding periplasmic protein DctP from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see paper)
    28% identity, 72% coverage of query (103 bits)

4n6kA / C6BWG5 Crystal structure of a trap periplasmic solute binding protein from desulfovibrio salexigens dsm2638, target efi-510113 (desal_0342), complex with diglycerolphosphate (see paper)
    25% identity, 93% coverage of query (102 bits)

DCTB_BACSU / P96600 C4-dicarboxylate-binding protein DctB from Bacillus subtilis (strain 168) (see paper)
    25% identity, 76% coverage of query (100 bits)

2v4cA Structure of sialic acid binding protein (siap) in the presence of kdn
    24% identity, 87% coverage of query (100 bits)

3b50A / P44542 Structure of h. Influenzae sialic acid binding protein bound to neu5ac. (see paper)
    24% identity, 87% coverage of query (99.8 bits)

2cexB Structure of a sialic acid binding protein (siap) in the presence of the sialic acid acid analogue neu5ac2en
    24% identity, 87% coverage of query (99.8 bits)

2wx9A Crystal structure of the sialic acid binding periplasmic protein siap
    24% identity, 87% coverage of query (99.8 bits)

2cexA Structure of a sialic acid binding protein (siap) in the presence of the sialic acid acid analogue neu5ac2en
    24% identity, 87% coverage of query (99.4 bits)

DCTP_PSEAE / Q9HU18 C4-dicarboxylate-binding periplasmic protein DctP from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    25% identity, 93% coverage of query (99.0 bits)

2xwoA Siap r147e mutant in complex with sialylamide
    24% identity, 87% coverage of query (97.1 bits)

Sama_2209 alpha-ketoglutarate TRAP transporter, solute receptor component from Shewanella amazonensis SB2B
    25% identity, 80% coverage of query (96.3 bits)

DCTP2_OLEA2 / Q315G1 Solute-binding protein Dde_0634 from Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20) (Desulfovibrio alaskensis) (see paper)
    24% identity, 93% coverage of query (95.1 bits)

4paiA / Q5LSJ5 Crystal structure of a trap periplasmic solute binding protein from ruegeria pomeroyi dss-3 (spo1773, target efi-510260) with bound 3- hydroxybenzoate (see paper)
    24% identity, 85% coverage of query (94.7 bits)

DCTP_RUEPO / Q5LSJ5 Solute-binding protein SPO1773 from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
    24% identity, 85% coverage of query (94.7 bits)

4napD / Q315G1 Crystal structure of a trap periplasmic solute binding protein from desulfovibrio alaskensis g20 (dde_0634), target efi-510102, with bound d-tryptophan (see paper)
    23% identity, 93% coverage of query (94.0 bits)

4pgpA Crystal structure of a trap periplasmic solute binding protein from desulfovibrio alaskensis g20 (dde_0634, target efi-510120) with bound 3-indole acetic acid
    23% identity, 93% coverage of query (94.0 bits)

4pgnA Crystal structure of a trap periplasmic solute binding protein from desulfovibrio alaskensis g20 (dde_0634, target efi-510120) with bound indole pyruvate
    23% identity, 93% coverage of query (94.0 bits)

TEAA_HALED / E1VBK1 Ectoine-binding periplasmic protein TeaA from Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9) (see 3 papers)
    26% identity, 83% coverage of query (89.7 bits)

4n6dA / C6C297 Crystal structure of a trap periplasmic solute binding protein from desulfovibrio salexigens dsm2638 (desal_3247), target efi-510112, phased with i3c, open complex, c-terminus of symmetry mate bound in ligand binding site (see paper)
    23% identity, 88% coverage of query (85.5 bits)

4n8gA / Q1QZT7 Crystal structure of a trap periplasmic solute binding protein from chromohalobacter salexigens dsm 3043 (csal_0660), target efi-501075, with bound d-alanine-d-alanine (see paper)
    27% identity, 81% coverage of query (82.8 bits)

DCTP_ALBFT / Q21XD7 Solute-binding protein Rfer_1840 from Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Rhodoferax ferrireducens) (see paper)
    26% identity, 94% coverage of query (78.6 bits)

TC 2.A.56.1.7 / Q930W1 ABC transporter, periplasmic solute-binding protein, component of The malonate uptake transporter, MatPQM. Regulated by the GtrA transcriptional activator (Chen et al. 2010). MatM is fused in a single protein C-terminal to MatA (malonyl-CoA decarboxylase) from Rhizobium meliloti (strain 1021)
    26% identity, 93% coverage of query (77.0 bits)

4pe3A / A3PQU4 Crystal structure of a trap periplasmic solute binding protein from rhodobacter sphaeroides (rsph17029_3620, target efi-510199), apo open structure (see paper)
    26% identity, 78% coverage of query (76.6 bits)

4nguA / Q311Q1 Crystal structure of a trap periplasmic solute binding protein from desulfovibrio alaskensis g20 (dde_1548), target efi-510103, with bound d-ala-d-ala (see paper)
    27% identity, 81% coverage of query (75.1 bits)

TMBP_NOSS1 / Q8YSQ6 Monocarboxylate 2-oxoacid-binding periplasmic protein all3028; Extracellular solute-binding protein; Extracytoplasmic solute receptor protein all3028; TRAP transporter monocarboxylate 2-oxoacid-binding subunit P from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) (see paper)
TC 2.A.56.3.3 / Q8YSQ6 Extracellular solute-binding protein, component of The 2-oxo monocarboxylate transporter (Pernil et al., 2010). Transports pyruvate which is inhibited by various 2-ketoacids from Nostoc sp. (strain PCC 7120 / UTEX 2576) (see paper)
    27% identity, 80% coverage of query (69.7 bits)

2pfzA / Q7VXB3 Crystal structure of dctp6, a bordetella pertussis extracytoplasmic solute receptor binding pyroglutamic acid (see paper)
    23% identity, 80% coverage of query (62.0 bits)

4p56B / A0A0H3LM73 Crystal structure of a trap periplasmic solute binding protein from bordetella bronchiseptica, target efi-510038 (bb2442), with bound (r)-mandelate and (s)-mandelate (see paper)
    24% identity, 76% coverage of query (61.2 bits)

4p56A Crystal structure of a trap periplasmic solute binding protein from bordetella bronchiseptica, target efi-510038 (bb2442), with bound (r)-mandelate and (s)-mandelate
    24% identity, 76% coverage of query (61.2 bits)

2pfyA / Q7VXB1 Crystal structure of dctp7, a bordetella pertussis extracytoplasmic solute receptor binding pyroglutamic acid (see paper)
    26% identity, 72% coverage of query (53.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory