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Searching for up to 100 curated homologs for GFF3717 FitnessBrowser__psRCH2:GFF3717 (539 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

B6E9W1 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Enterobacter hormaechei (see paper)
    51% identity, 98% coverage of query (559 bits)

F5S1H2 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Enterobacter hormaechei (see paper)
    51% identity, 98% coverage of query (548 bits)

5x7uA / D1CE96 Trehalose synthase from thermobaculum terrenum (see paper)
    42% identity, 99% coverage of query (408 bits)

D1CE96 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermobaculum terrenum (see 4 papers)
    42% identity, 99% coverage of query (408 bits)

Q47SE5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermobifida fusca (see paper)
    42% identity, 89% coverage of query (390 bits)

D1ABU6 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermomonospora curvata (see 2 papers)
    41% identity, 89% coverage of query (375 bits)

Q9RST7 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus radiodurans (see 2 papers)
    37% identity, 98% coverage of query (364 bits)

I3NX86 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus radiodurans (see 4 papers)
    37% identity, 98% coverage of query (364 bits)

B8YM30 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Paenarthrobacter aurescens (see 2 papers)
    37% identity, 99% coverage of query (363 bits)

Q1J0Z5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Deinococcus geothermalis (see paper)
    39% identity, 98% coverage of query (363 bits)

5gtwA / I3NX86 The n253r mutant structures of trehalose synthase from deinococcus radiodurans display two different active-site conformations
    37% identity, 98% coverage of query (363 bits)

A8QX00 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Actinoplanes sp. (see paper)
    40% identity, 89% coverage of query (361 bits)

Q5SL15 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see paper)
    41% identity, 98% coverage of query (358 bits)

Q6L2Z7 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Picrophilus torridus (see 2 papers)
    40% identity, 92% coverage of query (356 bits)

Q7WUI5 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see 2 papers)
    40% identity, 98% coverage of query (356 bits)

B1PK99 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Meiothermus ruber (see 4 papers)
    40% identity, 98% coverage of query (355 bits)

3zo9A The structure of trehalose synthase (tres) of mycobacterium smegmatis
    37% identity, 99% coverage of query (355 bits)

3zoaA The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose
    37% identity, 99% coverage of query (355 bits)

A0A1R4FYB1 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Corynebacterium glutamicum (see 2 papers)
    39% identity, 91% coverage of query (354 bits)

TRES_MYCTU / P9WQ19 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WQ19 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Mycobacterium tuberculosis (see paper)
    37% identity, 100% coverage of query (354 bits)

I3WCP4 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas sp. P8005 (see paper)
    36% identity, 98% coverage of query (352 bits)

Q88FN0 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas putida (see 2 papers)
    37% identity, 98% coverage of query (350 bits)

4lxfA Crystal structure of m. Tuberculosis tres (see paper)
    37% identity, 98% coverage of query (350 bits)

5jy7B / A0R6E0 Complex of mycobacterium smegmatis trehalose synthase with maltokinase (see paper)
    37% identity, 99% coverage of query (350 bits)

M1PA89 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Rhodococcus opacus (see paper)
    40% identity, 86% coverage of query (350 bits)

treS / A0R6E0 trehalose synthase subunit (EC 5.4.99.16) from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (see 4 papers)
TRES_MYCS2 / A0R6E0 Trehalose synthase/amylase TreS; Maltose alpha-D-glucosyltransferase; MTase; EC 3.2.1.1; EC 5.4.99.16 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see 6 papers)
A0R6E0 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Mycolicibacterium smegmatis (see 3 papers)
    37% identity, 99% coverage of query (350 bits)

3zoaB The structure of trehalose synthase (tres) of mycobacterium smegmatis in complex with acarbose
    37% identity, 99% coverage of query (350 bits)

5ykbD / I3NX86 The n253f mutant structure of trehalose synthase from deinococcus radiodurans reveals an open active-site conformation (see paper)
    36% identity, 98% coverage of query (348 bits)

A0A4S2BJW1 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas stutzeri (see paper)
    37% identity, 98% coverage of query (347 bits)

A0A1I7MT66 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Micrococcus terreus (see paper)
    36% identity, 99% coverage of query (347 bits)

O06458 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Thermus thermophilus (see 3 papers)
    40% identity, 98% coverage of query (346 bits)

A0A2Z4RCL2 maltose alpha-D-glucosyltransferase (EC 5.4.99.16) from Pseudomonas putida (see paper)
    36% identity, 98% coverage of query (346 bits)

4lxfB Crystal structure of m. Tuberculosis tres (see paper)
    35% identity, 98% coverage of query (323 bits)

AAS80455.1 α,α-trehalase / α-glucosidase (TTC0107) (EC 3.2.1.20|3.2.1.28) (see protein)
    33% identity, 91% coverage of query (231 bits)

CAA55409.1 α-1,4-glucosidase (MalA) (EC 3.2.1.20) (see protein)
    30% identity, 93% coverage of query (229 bits)

2ze0A / Q33E90 Alpha-glucosidase gsj (see paper)
    32% identity, 98% coverage of query (228 bits)

Q5FMB7 glucan 1,6-alpha-glucosidase (EC 3.2.1.70) from Lactobacillus acidophilus (see paper)
AAV42157.1 oligo-α-1,6-glucosidase (LBA0264) (EC 3.2.1.10) (see protein)
    31% identity, 97% coverage of query (228 bits)

4aieA / Q5FMB7 Structure of glucan-1,6-alpha-glucosidase from lactobacillus acidophilus ncfm (see paper)
    31% identity, 97% coverage of query (228 bits)

A0A223KY92 alpha-amylase (EC 3.2.1.1) from Sutcliffiella cohnii (see paper)
    30% identity, 98% coverage of query (227 bits)

Build an alignment

Build an alignment for GFF3717 and 39 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

5wczA Crystal structure of wild-type mall from bacillus subtilis with ts analogue 1-deoxynojirimycin
    29% identity, 97% coverage of query (226 bits)

4mazA The structure of mall mutant enzyme v200s from bacillus subtilus
    29% identity, 97% coverage of query (226 bits)

O16G1_BACSU / O06994 Oligo-1,6-glucosidase 1; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase 1; Sucrase-isomaltase 1; Isomaltase 1; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see 3 papers)
CAB15461.1 α-1,6-glucosidase (MalL;YvdL;BSU34560) (EC 3.2.1.10) (see protein)
    29% identity, 97% coverage of query (225 bits)

AKA95141.1 α-glucosidase (TtAG) (EC 3.2.1.20) (see protein)
    32% identity, 91% coverage of query (224 bits)

7lv6B / O06994 The structure of mall mutant enzyme s536r from bacillus subtilis
    29% identity, 97% coverage of query (224 bits)

4m56A The structure of wild-type mall from bacillus subtilis
    29% identity, 97% coverage of query (224 bits)

Q33E90 alpha-glucosidase (EC 3.2.1.20) from Geobacillus sp. HTA-462 (see paper)
BAE48285.1 α-glucosidase (Gsj) (EC 3.2.1.20) (see protein)
    31% identity, 98% coverage of query (223 bits)

O16G_PARTM / P29094 Oligo-1,6-glucosidase; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase; EC 3.2.1.10 from Parageobacillus thermoglucosidasius (Geobacillus thermoglucosidasius) (see paper)
BAA01368.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    29% identity, 98% coverage of query (223 bits)

BAA12704.1 α-glucosidase / exo-α-1,4-glucosidase (EC 3.2.1.20) (see protein)
    31% identity, 98% coverage of query (223 bits)

Q9F4G4 oligo-1,6-glucosidase (EC 3.2.1.10) from Bacillus subtilis (see paper)
AAG23399.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    29% identity, 97% coverage of query (222 bits)

ABU54057.1 α-amylase (BMW-amylase) (EC 3.2.1.1) (see protein)
    30% identity, 91% coverage of query (220 bits)

CAA37583.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    30% identity, 98% coverage of query (219 bits)

Q99040 glucan 1,6-alpha-glucosidase (EC 3.2.1.70) from Streptococcus mutans serotype c (see paper)
    30% identity, 93% coverage of query (219 bits)

8ibkA / A0A2Z5WH92 Crystal structure of bacillus sp. Ahu2216 gh13_31 alpha-glucosidase e256q/n258g in complex with maltotriose (see paper)
    29% identity, 91% coverage of query (219 bits)

ACE77085.1 oligosaccharide-producing multifunctional amylase (OPMA) (EC 2.4.1.-) (see protein)
    29% identity, 97% coverage of query (218 bits)

4wlcA / Q99040 Structure of dextran glucosidase with glucose (see paper)
    30% identity, 93% coverage of query (217 bits)

2zidA Crystal structure of dextran glucosidase e236q complex with isomaltotriose
    30% identity, 93% coverage of query (217 bits)

P20845 alpha-amylase (EC 3.2.1.1) from Priestia megaterium (see paper)
CAA30247.1 α-amylase (EC 3.2.1.1) (see protein)
    30% identity, 91% coverage of query (216 bits)

AAA26939.1 dextran α-1,6-glucosidase (DexB) (EC 3.2.1.70) (see protein)
    30% identity, 93% coverage of query (216 bits)

Q5SL12 alpha-glucosidase (EC 3.2.1.20) from Thermus thermophilus HB8 (see paper)
BAD70304.1 α-glucosidase (TTHA0481) (EC 3.2.1.20) (see protein)
    32% identity, 91% coverage of query (216 bits)

AAX84031.1 α-amylase (AmyF) (EC 3.2.1.1) (see protein)
    30% identity, 91% coverage of query (216 bits)

5do8B / Q8YAE6 1.8 angstrom crystal structure of listeria monocytogenes lmo0184 alpha-1,6-glucosidase (see paper)
    28% identity, 91% coverage of query (215 bits)

BAB18518.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    32% identity, 91% coverage of query (214 bits)

BAE79634.1 dextran α-1,6-glucosidase (DexB;SmDG) (EC 3.2.1.70) (see protein)
    31% identity, 93% coverage of query (214 bits)

AAP10934.1 oligo-α-1,6-glucosidase (BC4015) (EC 3.2.1.10) (see protein)
    29% identity, 98% coverage of query (214 bits)

AAF71997.1 α-glucosidase (EC 3.2.1.20) (see protein)
    29% identity, 98% coverage of query (213 bits)

D7VFY4 oligo-1,6-glucosidase (EC 3.2.1.10) from Lactiplantibacillus plantarum subsp. plantarum (see paper)
    29% identity, 91% coverage of query (212 bits)

CAA02858.1 palatinase / trehalulose hydrolase (MutA) (EC 3.2.1.10|3.2.1.-) (see protein)
    32% identity, 91% coverage of query (210 bits)

AAB82327.1 α-glucosidase 1 (Mav1) (EC 3.2.1.20) (see protein)
    30% identity, 91% coverage of query (209 bits)

BAA11354.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    28% identity, 92% coverage of query (208 bits)

BAC87873.1 α-transglucosidase (XgtA) (EC 2.4.1.-) (see protein)
    32% identity, 89% coverage of query (208 bits)

AAK28739.1 α-glucosidase (PalZ) (EC 3.2.1.20) (see protein)
    30% identity, 91% coverage of query (207 bits)

A1IHL0 alpha-glucosidase (EC 3.2.1.20) from Apis cerana japonica (see paper)
BAF44218.1 α-glucosidase I (JBgI) (EC 3.2.1.20) (see protein)
jbgI / BAF44218.1 alpha-glucosidase isozyme I from Apis cerana japonica (see paper)
    32% identity, 91% coverage of query (207 bits)

CAA60858.1 α-glucosidase (Agm2) (EC 3.2.1.20) (see protein)
    28% identity, 92% coverage of query (206 bits)

BAB38639.1 trehalose 6-P hydrolase (ECs5216) (EC 3.2.1.93) (see protein)
    31% identity, 90% coverage of query (205 bits)

BAE86926.1 α-glucosidase I (Hbg1;HBG-I;Loc409889) (EC 3.2.1.20) (see protein)
    32% identity, 91% coverage of query (204 bits)

AAL07400.1 α-amylase / neopullulanase (Npl) (EC 3.2.1.1) (see protein)
    28% identity, 93% coverage of query (202 bits)

Q9ZAP8 neopullulanase (EC 3.2.1.135) from Paenibacillus polymyxa (see paper)
AAD05199.1 α-amylase (formerly neopullulanase) (EC 3.2.1.1) (see protein)
    28% identity, 91% coverage of query (201 bits)

Dshi_1649 alpha-glucosidase / maltase / trehalase / sucrase (EC 3.2.1.48; EC 3.2.1.20; EC 3.2.1.28) from Dinoroseobacter shibae DFL-12
    31% identity, 97% coverage of query (201 bits)

AAA25570.1 α-glucosidase (Agl) (EC 3.2.1.20) (see protein)
    30% identity, 94% coverage of query (201 bits)

PGA1_c07890 cytoplasmic trehalase (AlgA) from Phaeobacter inhibens BS107
    31% identity, 91% coverage of query (201 bits)

TreE / b4239 trehalose-6-phosphate hydrolase (EC 3.2.1.93) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
treC / P28904 trehalose-6-phosphate hydrolase (EC 3.2.1.93) from Escherichia coli (strain K12) (see 4 papers)
TREC_ECOLI / P28904 Trehalose-6-phosphate hydrolase; Alpha,alpha-phosphotrehalase; EC 3.2.1.93 from Escherichia coli (strain K12) (see paper)
AAC77196.1 trehalose-6-phosphate hydrolase (TreC) (EC 3.2.1.93) (see protein)
    31% identity, 90% coverage of query (201 bits)

O16G2_BACSU / O34364 Probable oligo-1,6-glucosidase 2; Oligosaccharide alpha-1,6-glucosidase 2; Sucrase-isomaltase 2; Isomaltase 2; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see paper)
    28% identity, 91% coverage of query (199 bits)

BAG86620.1 trehalose-6-phosphate hydrolase (TreC;KP1_0530) (EC 3.2.1.93) (see protein)
    29% identity, 90% coverage of query (198 bits)

B5ABD8 isomaltulose synthase (EC 5.4.99.11) from Enterobacter sp. FMB-1 (see 3 papers)
    27% identity, 94% coverage of query (197 bits)

A0A0U4VEK2 alpha-amylase (EC 3.2.1.1) from Paenibacillus sp. SSG-1 (see paper)
    30% identity, 93% coverage of query (197 bits)

AO353_15985 Alpha,alpha-phosphotrehalase (EC 3.2.1.93) from Pseudomonas fluorescens FW300-N2E3
    28% identity, 97% coverage of query (197 bits)

D0VX20 isomaltulose synthase (EC 5.4.99.11) from Serratia plymuthica (see 4 papers)
3gbeA / D0VX20 Crystal structure of the isomaltulose synthase smua from protaminobacter rubrum in complex with the inhibitor deoxynojirimycin (see paper)
    26% identity, 92% coverage of query (196 bits)

S5YEW8 isomaltulose synthase (EC 5.4.99.11) from Pectobacterium carotovorum (see paper)
    28% identity, 90% coverage of query (196 bits)

BAE86927.1 α-glucosidase II (Hbg2;HBG-II;Loc411257) (EC 3.2.1.20) (see protein)
    29% identity, 91% coverage of query (196 bits)

Q9Z3R8 alpha-glucosidase (EC 3.2.1.20) from Sinorhizobium meliloti (see paper)
    31% identity, 91% coverage of query (196 bits)

palI / Q9AI64 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see 2 papers)
Q9AI64 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see paper)
    27% identity, 90% coverage of query (195 bits)

4howA / D9MPF2 The crystal structure of isomaltulose synthase from erwinia rhapontici nx5 (see paper)
    27% identity, 90% coverage of query (195 bits)

D9MPF2 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see 3 papers)
    27% identity, 90% coverage of query (195 bits)

AAG31032.1 trehalose-6-phosphate hydrolase (TreA) (EC 3.2.1.93) (see protein)
    28% identity, 91% coverage of query (194 bits)

4hphA The crystal structure of isomaltulose synthase mutant e295q from erwinia rhapontici nx5 in complex with its natural substrate sucrose
    27% identity, 90% coverage of query (194 bits)

J9SJ08 alpha-glucosidase (EC 3.2.1.20); mannosyl-oligosaccharide alpha-1,3-glucosidase (EC 3.2.1.207) from Apis cerana indica (see paper)
    29% identity, 91% coverage of query (192 bits)

Q6XNK5 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see paper)
    27% identity, 90% coverage of query (192 bits)

SLC31_HUMAN / Q07837 Amino acid transporter heavy chain SLC3A1; D2h; Neutral and basic amino acid transport protein; NBAT; Solute carrier family 3 member 1; b(0,+)-type amino acid transporter-related heavy chain; rBAT from Homo sapiens (Human) (see 24 papers)
    34% identity, 74% coverage of query (192 bits)

MAL3_DROME / P07192 Maltase A3; Larval visceral protein L; EC 3.2.1.20 from Drosophila melanogaster (Fruit fly) (see paper)
AAM50308.1 α-glucosidase L (LvpL) (EC 3.2.1.20) (see protein)
    31% identity, 74% coverage of query (192 bits)

ACN63343.1 sucrase / α-glucosidase II (JBgII;HBGaseII) (EC 3.2.1.20|3.2.1.-) (see protein)
    28% identity, 91% coverage of query (192 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory