Searching for up to 100 curated homologs for GFF375 FitnessBrowser__psRCH2:GFF375 (446 a.a.)
Found high-coverage hits (≥70%) to 26 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
gudD / P42206 D-glucarate dehydratase subunit (EC 4.2.1.40) from Pseudomonas putida (see paper)
GUDD_PSEPU / P42206 Glucarate dehydratase; GDH; GlucD; EC 4.2.1.40 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
80% identity, 99% coverage of query (721 bits)
YgcX / b2787 D-glucarate dehydratase (EC 4.2.1.40) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
gudD / P0AES2 D-glucarate dehydratase (EC 4.2.1.40) from Escherichia coli (strain K12) (see 5 papers)
GUDD_ECOLI / P0AES2 Glucarate dehydratase; GDH; GlucD; D-glucarate dehydratase; EC 4.2.1.40 from Escherichia coli (strain K12) (see 3 papers)
gudD / RF|NP_417267 glucarate dehydratase; EC 4.2.1.40 from Escherichia coli K12 (see 8 papers)
73% identity, 98% coverage of query (683 bits)
1ec9D / P0AES2 E. Coli glucarate dehydratase bound to xylarohydroxamate (see paper)
73% identity, 98% coverage of query (682 bits)
1ecqA E. Coli glucarate dehydratase bound to 4-deoxyglucarate
73% identity, 98% coverage of query (682 bits)
1ec8A E. Coli glucarate dehydratase bound to product 2,3-dihydroxy-5-oxo- hexanedioate
73% identity, 98% coverage of query (682 bits)
1jctA Glucarate dehydratase, n341l mutant orthorhombic form
73% identity, 98% coverage of query (679 bits)
gudD / Q6FFQ2 D-glucarate dehydratase subunit (EC 4.2.1.40) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
GUDD_ACIAD / Q6FFQ2 Glucarate dehydratase; GDH; GlucD; EC 4.2.1.40 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
Q6FFQ2 glucarate dehydratase (EC 4.2.1.40) from Acinetobacter baylyi (see paper)
69% identity, 99% coverage of query (664 bits)
3nxlC / Q39KL8 Crystal structure of glucarate dehydratase from burkholderia cepacia complexed with magnesium
68% identity, 98% coverage of query (572 bits)
3p0wB / B2UIZ1 Crystal structure of d-glucarate dehydratase from ralstonia solanacearum complexed with mg and d-glucarate
67% identity, 98% coverage of query (566 bits)
GudX / b2788 glucarate dehydratase-related protein from Escherichia coli K-12 substr. MG1655 (see 2 papers)
GUDX_ECOLI / Q46915 Glucarate dehydratase-related protein; GDH-RP; GlucDRP; EC 4.2.1.- from Escherichia coli (strain K12) (see paper)
gudX / RF|NP_417268 glucarate dehydratase-related protein from Escherichia coli K12
62% identity, 100% coverage of query (558 bits)
3nfuA / Q1QUN0 Crystal structure of probable glucarate dehydratase from chromohalobacter salexigens dsm 3043 complexed with magnesium
60% identity, 98% coverage of query (552 bits)
3n6hB / A6VQF6 Crystal structure of mandelate racemase/muconate lactonizing protein from actinobacillus succinogenes 130z complexed with magnesium/sulfate
58% identity, 98% coverage of query (507 bits)
3pfrA Crystal structure of d-glucarate dehydratase related protein from actinobacillus succinogenes complexed with d-glucarate
57% identity, 98% coverage of query (506 bits)
4it1D / Q3KB33 Crystal structure of enolase pfl01_3283 (target efi-502286) from pseudomonas fluorescens pf0-1 with bound magnesium, potassium and tartrate
38% identity, 96% coverage of query (241 bits)
3vc6A / D6Y7Y6 Crystal structure of enolase tbis_1083(target efi-502310) from thermobispora bispora dsm 43833 complexed with magnesium and formate
37% identity, 96% coverage of query (227 bits)
3va8A Crystal structure of enolase fg03645.1 (target efi-502278) from gibberella zeae ph-1 complexed with magnesium, formate and sulfate
35% identity, 97% coverage of query (227 bits)
Build an alignment for GFF375 and 16 homologs with ≥ 30% identity
Or download the sequences
D4GYD4 gluconate dehydratase (EC 4.2.1.39) from Haloferax volcanii (see paper)
24% identity, 84% coverage of query (73.2 bits)
araD / Q97U96 D-arabinonate dehydratase subunit (EC 4.2.1.5) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
ARAD_SACS2 / Q97U96 Arabinonate dehydratase; EC 4.2.1.5 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see paper)
Q97U96 Arabinonate dehydratase (EC 4.2.1.5) from Saccharolobus solfataricus (see paper)
25% identity, 80% coverage of query (66.6 bits)
3i6eA / Q5LM96 Crystal structure of muconate lactonizing enzyme from ruegeria pomeroyi.
27% identity, 76% coverage of query (61.6 bits)
xacD / D4GP40 D-xylonate dehydratase subunit (EC 4.2.1.25; EC 4.2.1.82) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
XAD_HALVD / D4GP40 D-xylonate dehydratase; XAD; EC 4.2.1.82 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
D4GP40 xylonate dehydratase (EC 4.2.1.82) from Haloferax volcanii (see paper)
25% identity, 84% coverage of query (59.7 bits)
5olcC / G0L7B8 Crystal structure of the 3,6-anhydro-d-galactonate cycloisomerase from zobellia galactanivorans (see paper)
26% identity, 85% coverage of query (58.9 bits)
3i6tB / Q28SI7 Crystal structure of muconate cycloisomerase from jannaschia sp.
26% identity, 83% coverage of query (56.2 bits)
3ozmA / A0A0H3LT39 Crystal structure of enolase superfamily member from bordetella bronchiseptica complexed with mg, m-xylarate and l-lyxarate
24% identity, 92% coverage of query (52.8 bits)
3ozmD Crystal structure of enolase superfamily member from bordetella bronchiseptica complexed with mg, m-xylarate and l-lyxarate
24% identity, 92% coverage of query (51.2 bits)
2ox4C / Q5NN22 Crystal structure of putative dehydratase from zymomonas mobilis zm4
21% identity, 91% coverage of query (48.1 bits)
3op2A Crystal structure of putative mandelate racemase from bordetella bronchiseptica rb50 complexed with 2-oxoglutarate/phosphate
24% identity, 92% coverage of query (45.1 bits)
Or start over
Lawrence Berkeley National Laboratory