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Searching for up to 100 curated homologs for GFF3754 FitnessBrowser__Marino:GFF3754 (689 a.a.)

Found high-coverage hits (≥70%) to 27 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO356_14165 Acyl-CoA dehydrogenase (EC 1.3.8.7) from Pseudomonas fluorescens FW300-N2C3
    58% identity, 88% coverage of query (729 bits)

PS417_25975 Acyl-CoA dehydrogenase (EC 1.3.8.7) from Pseudomonas simiae WCS417
    57% identity, 88% coverage of query (720 bits)

Q8L0X1 long-chain acyl-CoA dehydrogenase (EC 1.3.8.8) from Acinetobacter sp. (see paper)
    54% identity, 88% coverage of query (633 bits)

Psest_0419 Acyl-CoA dehydrogenase (EC 1.3.8.7) from Pseudomonas stutzeri RCH2
    50% identity, 87% coverage of query (572 bits)

BPHYT_RS03220 Acyl-CoA dehydrogenase (EC 1.3.8.7) from Burkholderia phytofirmans PsJN
    49% identity, 88% coverage of query (570 bits)

Q88L87 medium-chain acyl-CoA dehydrogenase (EC 1.3.8.7) from Pseudomonas putida (see paper)
    49% identity, 87% coverage of query (554 bits)

HP15_2478 Acyl-CoA dehydrogenase (EC 1.3.8.7) from Marinobacter adhaerens HP15
    48% identity, 86% coverage of query (553 bits)

AO353_07485 Acyl-CoA dehydrogenase (EC 1.3.8.7) from Pseudomonas fluorescens FW300-N2E3
    48% identity, 87% coverage of query (546 bits)

AO356_14190 Acyl-CoA dehydrogenase (EC 1.3.8.7) from Pseudomonas fluorescens FW300-N2C3
    49% identity, 87% coverage of query (545 bits)

PS417_25960 Acyl-CoA dehydrogenase (EC 1.3.8.7) from Pseudomonas simiae WCS417
    48% identity, 87% coverage of query (542 bits)

AZOBR_RS05755 Butyryl-CoA dehydrogenase (EC 1.3.8.1) from Azospirillum brasilense Sp245
    42% identity, 87% coverage of query (430 bits)

dmdC / Q5LLW7 3-(methylsulfanyl)propanoyl-CoA dehydrogenase monomer (EC 1.3.99.41) from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (see 2 papers)
DMDC_RUEPO / Q5LLW7 3-methylmercaptopropionyl-CoA dehydrogenase; EC 1.3.8.- from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see paper)
    41% identity, 86% coverage of query (429 bits)

Sama_1743 Acyl-CoA dehydrogenase (EC 1.3.8.-) from Shewanella amazonensis SB2B
    42% identity, 87% coverage of query (429 bits)

RR42_RS04580 Butyryl-CoA dehydrogenase (EC 1.3.8.1) from Cupriavidus basilensis FW507-4G11
    42% identity, 84% coverage of query (428 bits)

FADE5_MYCS2 / Q3L887 Broad-specificity linear acyl-CoA dehydrogenase FadE5; Long-chain-acyl-CoA dehydrogenase; Medium-chain-acyl-CoA dehydrogenase; Short-chain-acyl-CoA dehydrogenase; EC 1.3.8.8; EC 1.3.8.7; EC 1.3.8.1 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    34% identity, 87% coverage of query (298 bits)

6ksaB / Q3L887 Crystal structure of e447a acyl-coa dehydrogenase fade5 mutant from mycobacteria smegmatis in complex with c18coa (see paper)
    34% identity, 87% coverage of query (293 bits)

6lq8A Crystal structure of e447a acyl-coa dehydrogenase fade5 mutant from mycobacteria smegmatis in complex with c22coa
    34% identity, 87% coverage of query (293 bits)

6lq7A Crystal structure of e447a acyl-coa dehydrogenase fade5 mutant from mycobacteria smegmatis in complex with c17coa
    34% identity, 87% coverage of query (293 bits)

6lq6A Crystal structure of e447a acyl-coa dehydrogenase fade5 mutant from mycobacteria smegmatis in complex with c20coa
    34% identity, 87% coverage of query (293 bits)

6lq1A Crystal structure of e447a acyl-coa dehydrogenase fade5 mutant from mycobacteria smegmatis in complex with c8coa
    34% identity, 87% coverage of query (293 bits)

6lq0A Crystal structure of e447a acyl-coa dehydrogenase fade5 mutant from mycobacteria smegmatis in complex with c6coa
    34% identity, 87% coverage of query (293 bits)

6lpyA Crystal structure of e447a acyl-coa dehydrogenase fade5 mutant from mycobacteria smegmatis in complex with c4coa
    34% identity, 87% coverage of query (293 bits)

6ksbA Crystal structure of e447a m130g acyl-coa dehydrogenase fade5 mutant from mycobacteria smegmatis in complex with c16coa
    34% identity, 87% coverage of query (292 bits)

FADE5_MYCTU / O53666 Broad-specificity linear acyl-CoA dehydrogenase FadE5; Long-chain-acyl-CoA dehydrogenase; Medium-chain-acyl-CoA dehydrogenase; Short-chain-acyl-CoA dehydrogenase; EC 1.3.8.8; EC 1.3.8.7; EC 1.3.8.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
    35% identity, 87% coverage of query (282 bits)

6kseA / O53666 Crystal structure of e447a acyl-coa dehydrogenase fade5 mutant from mycobacteria tuberculosisin complex with c18coa (see paper)
    34% identity, 87% coverage of query (278 bits)

BCD1_SYNWW / Q0AVM4 Butyryl-CoA dehydrogenase Swol_1933; BCD; EC 1.3.8.1 from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) (see 2 papers)
    32% identity, 83% coverage of query (264 bits)

BCD2_SYNWW / Q0AVA8 Butyryl-CoA dehydrogenase Swol_2052; BCD; EC 1.3.8.1 from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) (see 2 papers)
    30% identity, 83% coverage of query (243 bits)

Build an alignment

Build an alignment for GFF3754 and 27 homologs with ≥ 30% identity

Select sequences

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory