Searching for up to 100 curated homologs for GFF4121 FitnessBrowser__Marino:GFF4121 (361 a.a.)
Found high-coverage hits (≥70%) to 24 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
4petA / Q48AL6 Crystal structure of a trap periplasmic solute binding protein from colwellia psychrerythraea (cps_0129, target efi-510097) with bound calcium and pyruvate (see paper)
62% identity, 91% coverage of query (454 bits)
5cm6A Crystal structure of a trap periplasmic solute binding protein from pseudoalteromonas atlantica t6c(patl_2292, target efi-510180) with bound sodium and pyruvate
61% identity, 91% coverage of query (443 bits)
TMBP_NOSS1 / Q8YSQ6 Monocarboxylate 2-oxoacid-binding periplasmic protein all3028; Extracellular solute-binding protein; Extracytoplasmic solute receptor protein all3028; TRAP transporter monocarboxylate 2-oxoacid-binding subunit P from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) (see paper)
TC 2.A.56.3.3 / Q8YSQ6 Extracellular solute-binding protein, component of The 2-oxo monocarboxylate transporter (Pernil et al., 2010). Transports pyruvate which is inhibited by various 2-ketoacids from Nostoc sp. (strain PCC 7120 / UTEX 2576) (see paper)
38% identity, 90% coverage of query (239 bits)
7ug8B / Q0I6F8 Crystal structure of a solute receptor from synechococcus cc9311 in complex with alpha-ketovaleric and calcium
37% identity, 88% coverage of query (221 bits)
TC 2.A.56.3.4 / D5ALT6 TRAP dicarboxylate transporter, DctP-2 subunit, component of The 2-ketomonocarboxylate transporter (presented in order of affinity - 2-oxovalerate [highest affinity, KD=0.1 μM], 2-oxoisovalerate, 2-oxobutyrate, 2-oxoisocaproate, 2-oxo-3-methylvalerate, pyruvate [lowest affinity, KD=3 μM]) from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003) (see paper)
36% identity, 89% coverage of query (214 bits)
TAKP_CERS4 / Q3J1R2 Alpha-keto acid-binding periplasmic protein TakP; Extracytoplasmic solute receptor protein TakP; TRAP transporter alpha-keto acid-binding subunit P; TRAP-T family sorbitol/mannitol transporter, periplasmic binding protein, SmoM from Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter sphaeroides) (see paper)
35% identity, 89% coverage of query (209 bits)
2hzlB / Q3J1R2 Crystal structures of a sodium-alpha-keto acid binding subunit from a trap transporter in its closed forms (see paper)
35% identity, 89% coverage of query (209 bits)
4yicA / A0A0J9X284 Crystal structure of a trap transporter solute binding protein (ipr025997) from bordetella bronchiseptica rb50 (bb0280, target efi- 500035) with bound picolinic acid
33% identity, 89% coverage of query (195 bits)
Build an alignment for GFF4121 and 8 homologs with ≥ 30% identity
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TLBP_THET8 / Q5SK82 Lactate-binding periplasmic protein TTHA0766; ABC transporter, solute-binding protein; Extracytoplasmic solute receptor protein TTHA0766; TRAP transporter lactate-binding subunit P from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
28% identity, 92% coverage of query (141 bits)
2zzvA / Q5SK82 Crystal structure of a periplasmic substrate binding protein in complex with calcium and lactate (see paper)
28% identity, 87% coverage of query (135 bits)
2zzwA Crystal structure of a periplasmic substrate binding protein in complex with zinc and lactate
28% identity, 87% coverage of query (135 bits)
SIAP_HAEIN / P44542 Sialic acid-binding periplasmic protein SiaP; Extracytoplasmic solute receptor protein SiaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 4 papers)
TC 2.A.56.1.3 / P44542 SiaP. AKA Sialic acid-binding periplasmic protein, component of Na+-dependent (smf-driven) sialic acid (N-acetyl neuraminic acid) transporter, SiaTP (Allen et al., 2005; Severi et al., 2005; Johnston et al., 2008). SiaT is also called SiaQM from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 4 papers)
24% identity, 71% coverage of query (65.9 bits)
DCTP2_POLSJ / Q122C7 Solute-binding protein Bpro_4736 from Polaromonas sp. (strain JS666 / ATCC BAA-500) (see paper)
27% identity, 71% coverage of query (63.5 bits)
4p8bA / Q0KC03 Crystal structure of a trap periplasmic solute binding protein from ralstonia eutropha h16 (h16_a1328), target efi-510189, with bound (s)-2-hydroxy-2-methyl-3-oxobutanoate ((s)-2-acetolactate) (see paper)
23% identity, 78% coverage of query (58.5 bits)
Ac3H11_3226 gluconate TRAP transporter, periplasmic solute-binding component from Acidovorax sp. GW101-3H11
27% identity, 72% coverage of query (55.8 bits)
PP_1169 D-glucuronate / D-galacturonate TRAP transporter, solute receptor component from Pseudomonas putida KT2440
25% identity, 74% coverage of query (54.7 bits)
DCTP_ALBFT / Q21XD7 Solute-binding protein Rfer_1840 from Albidiferax ferrireducens (strain ATCC BAA-621 / DSM 15236 / T118) (Rhodoferax ferrireducens) (see paper)
24% identity, 71% coverage of query (53.9 bits)
DCTP_OLEA2 / Q312S0 Isethionate-binding periplasmic protein DctP; TRAP transporter, DctP solute-binding subunit from Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20) (Desulfovibrio alaskensis) (see paper)
23% identity, 78% coverage of query (53.5 bits)
4pgpA Crystal structure of a trap periplasmic solute binding protein from desulfovibrio alaskensis g20 (dde_0634, target efi-510120) with bound 3-indole acetic acid
22% identity, 74% coverage of query (50.4 bits)
4pgnA Crystal structure of a trap periplasmic solute binding protein from desulfovibrio alaskensis g20 (dde_0634, target efi-510120) with bound indole pyruvate
22% identity, 74% coverage of query (50.4 bits)
4napD / Q315G1 Crystal structure of a trap periplasmic solute binding protein from desulfovibrio alaskensis g20 (dde_0634), target efi-510102, with bound d-tryptophan (see paper)
22% identity, 74% coverage of query (50.4 bits)
YiaO / b3579 2,3-diketo-L-gulonate:Na+ symporter - periplasmic binding protein from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yiaO / P37676 2,3-diketo-L-gulonate:Na+ symporter - periplasmic binding protein from Escherichia coli (strain K12) (see 5 papers)
YIAO_ECOLI / P37676 2,3-diketo-L-gulonate-binding periplasmic protein YiaO; 2,3-DKG-binding protein; Extracytoplasmic solute receptor protein YiaO from Escherichia coli (strain K12) (see paper)
TC 2.A.56.1.2 / P37676 YiaO, component of The 2,3-diketo-L-gulonate (2,3-DKG) transporter, YiaMNO [2,3-KDG is a breakdown product of L-ascorbate] from Escherichia coli (see 6 papers)
24% identity, 80% coverage of query (48.9 bits)
4p56B / A0A0H3LM73 Crystal structure of a trap periplasmic solute binding protein from bordetella bronchiseptica, target efi-510038 (bb2442), with bound (r)-mandelate and (s)-mandelate (see paper)
25% identity, 71% coverage of query (47.4 bits)
4p56A Crystal structure of a trap periplasmic solute binding protein from bordetella bronchiseptica, target efi-510038 (bb2442), with bound (r)-mandelate and (s)-mandelate
25% identity, 71% coverage of query (47.0 bits)
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Lawrence Berkeley National Laboratory