Searching for up to 100 curated homologs for GFF4259 FitnessBrowser__WCS417:GFF4259 (500 a.a.)

Found high-coverage hits (≥70%) to 35 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

pam / GI|19744118 peptide amidase from Stenotrophomonas maltophilia (see paper)
pam / CAC93616.1 peptide amidase from Stenotrophomonas maltophilia (see paper)
    44% identity, 96% coverage of query (291 bits)

1m21A / Q8RJN5 Crystal structure analysis of the peptide amidase pam in complex with the competitive inhibitor chymostatin (see paper)
    45% identity, 90% coverage of query (291 bits)

AMI4G_ARATH / A0A1P8B760 Probable amidase At4g34880; EC 3.5.1.4 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    38% identity, 90% coverage of query (261 bits)

YI01_SCHPO / Q9URY4 Putative amidase C869.01; EC 3.5.1.4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    33% identity, 96% coverage of query (218 bits)

A2965_ARTBC / D4B3C8 Putative amidase ARB_02965; EC 3.5.1.- from Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) (see 2 papers)
    34% identity, 87% coverage of query (210 bits)

cahA / BAC15598.1 carbaryl hydrolase from Arthrobacter sp. RC100 (see paper)
    34% identity, 88% coverage of query (158 bits)

P63488 glutaminyl-tRNA synthase (glutamine-hydrolysing) (subunit 2/2) (EC 6.3.5.7) from Staphylococcus aureus (see paper)
2dqnA / P63488 Structure of tRNA-dependent amidotransferase gatcab complexed with asn (see paper)
    32% identity, 87% coverage of query (147 bits)

2f2aA Structure of tRNA-dependent amidotransferase gatcab complexed with gln
    32% identity, 87% coverage of query (147 bits)

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Build an alignment for GFF4259 and 8 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

GATA_HUMAN / Q9H0R6 Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Glu-AdT subunit A; Glutaminyl-tRNA synthase-like protein 1; EC 6.3.5.7 from Homo sapiens (Human) (see 3 papers)
Q9H0R6 glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Homo sapiens (see paper)
    29% identity, 89% coverage of query (143 bits)

Q9CZN8 glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Mus musculus (see paper)
    29% identity, 89% coverage of query (138 bits)

gatA / Q9RTA9 glutamyl-tRNA^Gln amidotransferase subunit A (EC 6.3.5.7; EC 6.3.5.6) from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see paper)
    33% identity, 82% coverage of query (137 bits)

gatA / O06491 glutamyl-tRNA^Gln amidotransferase subunit A (EC 6.3.5.7) from Bacillus subtilis (strain 168) (see paper)
GATA_BACSU / O06491 Glutamyl-tRNA(Gln) amidotransferase subunit A; Glu-ADT subunit A; EC 6.3.5.7 from Bacillus subtilis (strain 168) (see 2 papers)
    32% identity, 92% coverage of query (136 bits)

FAAH_ARATH / Q7XJJ7 Fatty acid amide hydrolase; AtFAAH; N-acylethanolamine amidohydrolase; EC 3.5.1.99 from Arabidopsis thaliana (Mouse-ear cress) (see 10 papers)
Q7XJJ7 fatty acid amide hydrolase (EC 3.5.1.99) from Arabidopsis thaliana (see paper)
    30% identity, 84% coverage of query (126 bits)

6diiH / Q7XJJ7 Structure of arabidopsis fatty acid amide hydrolase in complex with methyl linolenyl fluorophosphonate (see paper)
    30% identity, 84% coverage of query (126 bits)

3h0lA / O66610 Structure of tRNA-dependent amidotransferase gatcab from aquifex aeolicus (see paper)
    30% identity, 90% coverage of query (123 bits)

3h0mA Structure of tRNA-dependent amidotransferase gatcab from aquifex aeolicus
    30% identity, 90% coverage of query (123 bits)

MANHY_PSEPU / Q84DC4 Mandelamide hydrolase; EC 3.5.1.86 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
    30% identity, 87% coverage of query (114 bits)

FAAH_MEDTR / G7ISB0 Fatty acid amide hydrolase; N-acylethanolamine amidohydrolase; EC 3.5.1.- from Medicago truncatula (Barrel medic) (Medicago tribuloides) (see paper)
    31% identity, 79% coverage of query (110 bits)

GATA_ARATH / Q9LI77 Glutamyl-tRNA(Gln) amidotransferase subunit A, chloroplastic/mitochondrial; Glu-AdT subunit A; EC 6.3.5.7 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    29% identity, 89% coverage of query (109 bits)

DUR1,2 / P32528 urea amidolyase (EC 6.3.4.6) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 6 papers)
DUR1_YEAST / P32528 Urea amidolyase; EC 6.3.4.6; EC 3.5.1.54 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P32528 allophanate hydrolase (EC 3.5.1.54); urea carboxylase (EC 6.3.4.6) from Saccharomyces cerevisiae (see 3 papers)
    27% identity, 78% coverage of query (108 bits)

Q9X0Z9 glutaminyl-tRNA synthase (glutamine-hydrolysing) (EC 6.3.5.7) from Thermotoga maritima (see paper)
    29% identity, 85% coverage of query (107 bits)

DUR1.2 / AAC41643.1 urea amidolyase from Saccharomyces cerevisiae (see paper)
    26% identity, 78% coverage of query (107 bits)

FAAH_ORYSJ / Q0JFH7 Fatty acid amide hydrolase; N-acylethanolamine amidohydrolase; EC 3.5.1.- from Oryza sativa subsp. japonica (Rice) (see paper)
    27% identity, 84% coverage of query (104 bits)

A0A1D8PDC6 allophanate hydrolase (EC 3.5.1.54) from Candida albicans (see paper)
    29% identity, 79% coverage of query (103 bits)

DUR1,2 likely multifunctional urea amidolyase from Candida albicans (see paper)
    29% identity, 79% coverage of query (103 bits)

3a1iA / Q7DKE4 Crystal structure of rhodococcus sp. N-771 amidase complexed with benzamide (see paper)
    28% identity, 78% coverage of query (96.7 bits)

DUR1_LACKL / A5H0J2 Urea amidolyase; Pyrimidine-degrading protein 13,15; Uracil catabolism protein 3,5; EC 6.3.4.6; EC 3.5.1.54 from Lachancea kluyveri (Yeast) (Saccharomyces kluyveri) (see paper)
    28% identity, 78% coverage of query (95.9 bits)

C3UWD1 aryl-acylamidase (EC 3.5.1.13) from bacterium CSBL00001 (see 2 papers)
    27% identity, 85% coverage of query (95.9 bits)

tms2 / P0A2X0 indoleacetamide hydrolase (EC 3.5.1.4) from Rhizobium radiobacter (see paper)
    26% identity, 88% coverage of query (95.1 bits)

4yjiA / C3UWD1 The crystal structure of a bacterial aryl acylamidase belonging to the amidase signature (as) enzymes family (see paper)
    27% identity, 85% coverage of query (94.4 bits)

CNBH_COMTE / Q38M35 2-amino-5-chloromuconic acid deaminase; 2-aminomuconate deaminase; EC 3.5.99.5 from Comamonas testosteroni (Pseudomonas testosteroni) (see paper)
    26% identity, 87% coverage of query (94.4 bits)

Q6CP22 allophanate hydrolase (EC 3.5.1.54); urea carboxylase (EC 6.3.4.6) from Kluyveromyces lactis (see 3 papers)
    28% identity, 78% coverage of query (93.2 bits)

atzF / Q936X2 allophanate hydrolase subunit from Pseudomonas sp. (strain ADP) (see 2 papers)
ATZF_PSESD / Q936X2 Allophanate hydrolase; EC 3.5.1.54 from Pseudomonas sp. (strain ADP) (see 2 papers)
Q936X2 allophanate hydrolase (EC 3.5.1.54) from Pseudomonas sp. ADP (see paper)
    27% identity, 86% coverage of query (89.0 bits)

Q9ALV2 allophanate hydrolase (EC 3.5.1.54) from Enterobacter cloacae (see 2 papers)
    27% identity, 84% coverage of query (81.3 bits)

5h6sC Crystal structure of hydrazidase s179a mutant complexed with a substrate (see paper)
    27% identity, 88% coverage of query (77.8 bits)

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