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Searching for up to 100 curated homologs for GFF4431 FitnessBrowser__WCS417:GFF4431 (318 a.a.)

Found high-coverage hits (≥70%) to 11 curated proteins.

Removed hits that are identical to the query, leaving 10

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

1sz2B / P0A6V9 Crystal structure of e. Coli glucokinase in complex with glucose (see paper)
    40% identity, 99% coverage of query (217 bits)

Glk / b2388 glucokinase (EC 2.7.1.1; EC 2.7.1.2; EC 2.7.1.8) from Escherichia coli K-12 substr. MG1655 (see 11 papers)
glk / P0A6V8 glucokinase (EC 2.7.1.1; EC 2.7.1.8) from Escherichia coli (strain K12) (see 11 papers)
GLK_ECOLI / P0A6V8 Glucokinase; Glucose kinase; EC 2.7.1.2 from Escherichia coli (strain K12) (see paper)
    40% identity, 99% coverage of query (217 bits)

glk / AAC43672.1 glucokinase from Brucella abortus (see paper)
    39% identity, 96% coverage of query (189 bits)

Dshi_1655 glucokinase (EC 2.7.1.2) from Dinoroseobacter shibae DFL-12
    32% identity, 98% coverage of query (146 bits)

G4T1H4 glucokinase (EC 2.7.1.2) from Methylotuvimicrobium alcaliphilum (see paper)
    31% identity, 97% coverage of query (98.2 bits)

Build an alignment

Build an alignment for GFF4431 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

GL50803_8826 / E2RU42 glucokinase (EC 2.7.1.1) from Giardia intestinalis (strain ATCC 50803 / WB clone C6) (see 3 papers)
    27% identity, 97% coverage of query (84.0 bits)

A0A3G4RI75 glucokinase (EC 2.7.1.2) from Methylomonas methanica (see paper)
    29% identity, 97% coverage of query (84.0 bits)

PGA1_c05420 glucokinase (EC 2.7.1.2) from Phaeobacter inhibens BS107
    29% identity, 98% coverage of query (81.3 bits)

A0A384E136 glucokinase (EC 2.7.1.2) from Naegleria fowleri (see paper)
    24% identity, 83% coverage of query (48.1 bits)

6da0A / A0A384E136 Crystal structure of glucokinase (nfhk) from naegleria fowleri (see paper)
    24% identity, 83% coverage of query (48.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory