Searching for up to 100 curated homologs for GFF453 FitnessBrowser__WCS417:GFF453 (308 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
6wj9B / Q4KCF6 Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-glcnac (see paper)
67% identity, 99% coverage of query (401 bits)
6wjaA Udp-glcnac c4-epimerase mutant s121a/y146f from pseudomonas protegens in complex with udp-galnac
68% identity, 98% coverage of query (400 bits)
F2NQX6 UDP-glucose 4-epimerase (EC 5.1.3.2) from Marinithermus hydrothermalis (see paper)
41% identity, 98% coverage of query (206 bits)
Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
38% identity, 98% coverage of query (204 bits)
F6DEY6 UDP-glucose 4-epimerase (EC 5.1.3.2) from Thermus thermophilus (see paper)
42% identity, 97% coverage of query (197 bits)
2p5uA / Q5SKQ2 Crystal structure of thermus thermophilus hb8 udp-glucose 4-epimerase complex with NAD
42% identity, 97% coverage of query (196 bits)
6dntA / D3E402 Udp-n-acetylglucosamine 4-epimerase from methanobrevibacter ruminantium m1 in complex with udp-n-acetylmuramic acid (see paper)
38% identity, 92% coverage of query (195 bits)
UAE / Q868I5 UDP-N-acetylglucosamine 4'-epimerase (EC 5.1.3.7) from Giardia intestinalis (see 7 papers)
34% identity, 98% coverage of query (179 bits)
GALE_MYCS2 / A0R5C5 UDP-glucose 4-epimerase; UDP-galactose 4-epimerase; Uridine diphosphate galactose 4-epimerase; EC 5.1.3.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
39% identity, 99% coverage of query (164 bits)
3lu1A / Q7BJX9 Crystal structure analysis of wbgu: a udp-galnac 4-epimerase (see paper)
35% identity, 91% coverage of query (162 bits)
Q8KN66 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Pseudomonas aeruginosa (see paper)
1sb8A / Q8KN66 Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-n-acetylgalactosamine (see paper)
36% identity, 91% coverage of query (162 bits)
3ruhA Alternative analogs as viable substrates of udp-hexose 4-epimerases
35% identity, 91% coverage of query (162 bits)
3rufA Alternative analogs as viable substrates of udp-hexose 4-epimerases
35% identity, 91% coverage of query (162 bits)
1sb9A Crystal structure of pseudomonas aeruginosa udp-n-acetylglucosamine 4- epimerase complexed with udp-glucose
36% identity, 91% coverage of query (162 bits)
wbpP / Q9RHD6 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Pseudomonas aeruginosa (see 8 papers)
35% identity, 91% coverage of query (158 bits)
wbgU / Q7BJX9 UDP-N-acetylglucosamine C4-epimerase subunit (EC 5.1.3.7) from Plesiomonas shigelloides (see paper)
GNE_PLESH / Q7BJX9 UDP-N-acetylglucosamine 4-epimerase; UDP-GalNAc 4-epimerase; EC 5.1.3.7 from Plesiomonas shigelloides (Aeromonas shigelloides) (see 3 papers)
Q7BJX9 UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Plesiomonas shigelloides (see 2 papers)
36% identity, 91% coverage of query (158 bits)
8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
36% identity, 89% coverage of query (157 bits)
6zllA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-galacturonic acid and NAD (see paper)
30% identity, 97% coverage of query (147 bits)
6zldA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-glucuronic acid and NAD
30% identity, 97% coverage of query (147 bits)
6zl6A Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp and NAD
30% identity, 97% coverage of query (147 bits)
O73960 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrococcus horikoshii (see paper)
33% identity, 89% coverage of query (146 bits)
galE1 / P9WN67 UDP-galactose/glucose 4-epimerase subunit (EC 5.1.3.7; EC 5.1.3.2) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WN67 UDP-glucose 4-epimerase (EC 5.1.3.2) from Mycobacterium tuberculosis (see paper)
39% identity, 90% coverage of query (146 bits)
7ystA / P9WN67 Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chain b from mycobacterium tuberculosis
39% identity, 90% coverage of query (146 bits)
7ys9A Crystal structure of udp-glucose 4-epimerase (rv3634c) in complex with both udp-glucose and udp-galactose in chaina from mycobacterium tuberculosis
39% identity, 90% coverage of query (146 bits)
7ysmA Crystal structure of udp-glucose 4-epimerase (rv3634c) co-crystallized with udp-n-acetylglucosamine from mycobacterium tuberculosis
39% identity, 90% coverage of query (146 bits)
A3MUJ4 UDP-glucose 4-epimerase (EC 5.1.3.2) from Pyrobaculum calidifontis (see paper)
34% identity, 92% coverage of query (145 bits)
6zljA Crystal structure of udp-glucuronic acid 4-epimerase y149f mutant from bacillus cereus in complex with udp-4-deoxy-4-fluoro-glucuronic acid and NAD
30% identity, 97% coverage of query (145 bits)
Q75PK6 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-1 / BAD12491.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
35% identity, 98% coverage of query (143 bits)
6bwlA / Q3ESA4 X-ray structure of pal from bacillus thuringiensis (see paper)
32% identity, 97% coverage of query (142 bits)
6pnlA / O26475 Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
35% identity, 93% coverage of query (141 bits)
uxs1 / Q92WA4 UDP-xylose synthase 1 subunit (EC 4.1.1.35) from Rhizobium meliloti (strain 1021) (see paper)
32% identity, 92% coverage of query (141 bits)
6pmhA Structure of epimerase mth375 from the thermophilic pseudomurein- containing methanogen methanothermobacter thermautotrophicus
35% identity, 98% coverage of query (141 bits)
UXS1 / Q8VZC0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
UXS1_ARATH / Q8VZC0 UDP-glucuronic acid decarboxylase 1; UDP-XYL synthase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q8VZC0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
32% identity, 98% coverage of query (140 bits)
N0A0C4 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
32% identity, 98% coverage of query (139 bits)
N0A8N3 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
34% identity, 89% coverage of query (139 bits)
UXS1_RAT / Q5PQX0 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; EC 4.1.1.35 from Rattus norvegicus (Rat) (see paper)
32% identity, 98% coverage of query (138 bits)
UXS1_HUMAN / Q8NBZ7 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UGD; UXS-1; hUXS; hUXS1; EC 4.1.1.35 from Homo sapiens (Human) (see 3 papers)
32% identity, 98% coverage of query (138 bits)
2b69A / Q8NBZ7 Crystal structure of human udp-glucoronic acid decarboxylase
32% identity, 98% coverage of query (138 bits)
Q8W3J1 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-4 / BAB84333.2 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
35% identity, 88% coverage of query (137 bits)
2q1sA / O87989 Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with nadh (see paper)
32% identity, 88% coverage of query (137 bits)
2q1tA Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with NAD+ and udp
32% identity, 88% coverage of query (137 bits)
2pzjA Crystal structure of the bordetella bronchiseptica enzyme wbmf in complex with NAD+
32% identity, 88% coverage of query (137 bits)
Q75PK7 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-2 / BAD12490.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
32% identity, 97% coverage of query (136 bits)
1udaA Structure of udp-galactose-4-epimerase complexed with udp-4-deoxy-4- fluoro-alpha-d-galactose
32% identity, 89% coverage of query (135 bits)
1naiA Udp-galactose 4-epimerase from escherichia coli, oxidized
32% identity, 89% coverage of query (135 bits)
1lrjA Crystal structure of e. Coli udp-galactose 4-epimerase complexed with udp-n-acetylglucosamine
32% identity, 89% coverage of query (135 bits)
uxe / Q92WA3 UDP-xylose 4-epimerase subunit (EC 5.1.3.5) from Rhizobium meliloti (strain 1021) (see paper)
Q92WA3 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Sinorhizobium meliloti (see paper)
34% identity, 89% coverage of query (134 bits)
Q8W3J0 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Oryza sativa (see paper)
UXS-3 / BAB84334.1 UDP-glucuronic acid decarboxylase from Oryza sativa Japonica Group (see paper)
34% identity, 90% coverage of query (134 bits)
UXS1_DANRE / Q6GMI9 UDP-glucuronic acid decarboxylase 1; UDP-glucuronate decarboxylase 1; UXS-1; EC 4.1.1.35 from Danio rerio (Zebrafish) (Brachydanio rerio) (see 3 papers)
31% identity, 99% coverage of query (133 bits)
N0A414 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
35% identity, 83% coverage of query (133 bits)
UGA4E_THEGP / F8C4X8 UDP-glucuronate 4-epimerase; UGA4E; TgUGAE; EC 5.1.3.6 from Thermodesulfobacterium geofontis (strain OPF15)
30% identity, 97% coverage of query (132 bits)
GALE_LACHE / Q7WTB1 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Lactobacillus helveticus (Lactobacillus suntoryeus) (see paper)
32% identity, 88% coverage of query (132 bits)
GalD / b0759 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli K-12 substr. MG1655 (see 42 papers)
galE / P09147 UDP-glucose 4-epimerase (EC 5.1.3.2) from Escherichia coli (strain K12) (see 38 papers)
GALE_ECOLI / P09147 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Escherichia coli (strain K12) (see 13 papers)
32% identity, 89% coverage of query (132 bits)
4lk3B / Q8NBZ7 Crystal structure of human udp-xylose synthase r236a substitution (see paper)
33% identity, 90% coverage of query (132 bits)
2udpA Udp-galactose 4-epimerase complexed with udp-phenol
32% identity, 89% coverage of query (132 bits)
1udcA Structure of udp-galactose-4-epimerase complexed with udp-mannose
32% identity, 89% coverage of query (132 bits)
N0A422 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
35% identity, 83% coverage of query (131 bits)
Q2LC83 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Hordeum vulgare (see paper)
34% identity, 92% coverage of query (131 bits)
UXS2 / Q9LZI2 subunit of UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see 3 papers)
UXS2_ARATH / Q9LZI2 UDP-glucuronic acid decarboxylase 2; UDP-XYL synthase 2; UDP-glucuronate decarboxylase 2; UGD; UXS-2; dTDP-glucose 4-6-dehydratase homolog D18; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9LZI2 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
33% identity, 88% coverage of query (131 bits)
1kvrA Udp-galactose 4-epimerase complexed with udp-phenol
32% identity, 89% coverage of query (131 bits)
N0A8N8 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
35% identity, 83% coverage of query (130 bits)
N0A9U2 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Populus tomentosa (see paper)
34% identity, 99% coverage of query (130 bits)
4lk3C Crystal structure of human udp-xylose synthase r236a substitution
34% identity, 84% coverage of query (130 bits)
1a9yA / P09147 Udp-galactose 4-epimerase mutant s124a/y149f complexed with udp- glucose (see paper)
31% identity, 89% coverage of query (129 bits)
galE / P55180 UDP-glucose 4-epimerase (EC 5.1.3.7; EC 5.1.3.2) from Bacillus subtilis (strain 168) (see 5 papers)
galE / CAA67713.1 UDP-glucose 4-epimerase from Bacillus subtilis (see paper)
33% identity, 88% coverage of query (129 bits)
GALE_NEIMC / P56986 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Neisseria meningitidis serogroup C (see paper)
galE / AAA86716.1 UDP-glucose 4-epimerase from Neisseria meningitidis (see paper)
30% identity, 89% coverage of query (128 bits)
epsS / BAC55147.1 UDP-glucose 4-epimerase EpsS from Methylobacillus sp. 12S (see paper)
32% identity, 88% coverage of query (128 bits)
UXS3 / Q9FIE8 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see 2 papers)
UXS3_ARATH / Q9FIE8 UDP-glucuronic acid decarboxylase 3; UDP-XYL synthase 3; UDP-glucuronate decarboxylase 3; UGD; UXS-3; EC 4.1.1.35 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
Q9FIE8 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
35% identity, 83% coverage of query (127 bits)
galE / CAB44218.1 UDP-galactose 4-epimerase from Lactococcus lactis (see paper)
31% identity, 88% coverage of query (127 bits)
GALE_NEIMB / P56985 UDP-glucose 4-epimerase; Galactowaldenase; UDP-galactose 4-epimerase; EC 5.1.3.2 from Neisseria meningitidis serogroup B (strain MC58) (see paper)
galE1 / AAA65535.1 UDP-glucose 4-epimerase from Neisseria meningitidis (see paper)
30% identity, 89% coverage of query (127 bits)
4twrA / Q2YKG6 Structure of udp-glucose 4-epimerase from brucella abortus
33% identity, 89% coverage of query (127 bits)
Q9SN95 UDP-glucuronate decarboxylase (EC 4.1.1.35) from Arabidopsis thaliana (see paper)
35% identity, 83% coverage of query (127 bits)
MUR4 / Q9SA77 UDP-D-xylose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see 3 papers)
ARAE1_ARATH / Q9SA77 UDP-arabinose 4-epimerase 1; UDP-D-xylose 4-epimerase 1; EC 5.1.3.5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9SA77 UDP-arabinose 4-epimerase (EC 5.1.3.5) from Arabidopsis thaliana (see paper)
32% identity, 88% coverage of query (125 bits)
1r6dA Crystal structure of desiv double mutant (dtdp-glucose 4,6- dehydratase) from streptomyces venezuelae with NAD and dau bound
37% identity, 70% coverage of query (124 bits)
1r66A / Q9ZGH3 Crystal structure of desiv (dtdp-glucose 4,6-dehydratase) from streptomyces venezuelae with NAD and tyd bound (see paper)
37% identity, 70% coverage of query (124 bits)
6kv9A / A0A003 Moee5 in complex with udp-glucuronic acid and NAD (see paper)
33% identity, 98% coverage of query (124 bits)
6kvcA Moee5 in complex with udp-glucose and NAD
32% identity, 98% coverage of query (123 bits)
5u4qA 1.5 angstrom resolution crystal structure of NAD-dependent epimerase from klebsiella pneumoniae in complex with NAD.
30% identity, 89% coverage of query (123 bits)
3aw9A / A3MUJ4 Structure of udp-galactose 4-epimerase mutant
32% identity, 92% coverage of query (120 bits)
8sk0A Crystal structure of evds6 decarboxylase in ligand bound state
31% identity, 97% coverage of query (116 bits)
8sk0B / A0A1C5ADV9 Crystal structure of evds6 decarboxylase in ligand bound state (see paper)
31% identity, 97% coverage of query (116 bits)
Build an alignment for GFF453 and 81 homologs with ≥ 30% identity
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3eheA / O29886 Crystal structure of udp-glucose 4 epimerase (gale-1) from archaeoglobus fulgidus
29% identity, 86% coverage of query (115 bits)
GALE / Q14376 UDP-galactose 4-epimerase (EC 5.1.3.2; EC 5.1.3.7) from Homo sapiens (see 6 papers)
GALE_HUMAN / Q14376 UDP-glucose 4-epimerase; Galactowaldenase; UDP-N-acetylgalactosamine 4-epimerase; UDP-GalNAc 4-epimerase; UDP-N-acetylglucosamine 4-epimerase; UDP-GlcNAc 4-epimerase; UDP-galactose 4-epimerase; EC 5.1.3.2; EC 5.1.3.7 from Homo sapiens (Human) (see 12 papers)
Q14376 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Homo sapiens (see 4 papers)
31% identity, 100% coverage of query (114 bits)
1ek6A Structure of human udp-galactose 4-epimerase complexed with nadh and udp-glucose
31% identity, 100% coverage of query (114 bits)
7k3pA / Q0P9C3 The structure of the udp-glc/glcnac 4-epimerase from the human pathogen campylobacter jejuni
29% identity, 93% coverage of query (114 bits)
5u4qB 1.5 angstrom resolution crystal structure of NAD-dependent epimerase from klebsiella pneumoniae in complex with NAD.
30% identity, 84% coverage of query (113 bits)
1hzjA Human udp-galactose 4-epimerase: accommodation of udp-n- acetylglucosamine within the active site
31% identity, 99% coverage of query (112 bits)
2hunA / O58151 Crystal structure of hypothetical protein ph0414 from pyrococcus horikoshii ot3
32% identity, 85% coverage of query (111 bits)
3vpsA / E5KJ94 Structure of a novel NAD dependent-ndp-hexosamine 5,6-dehydratase, tuna, involved in tunicamycin biosynthesis
33% identity, 82% coverage of query (110 bits)
1i3lA Molecular basis for severe epimerase-deficiency galactosemia: x-ray structure of the human v94m-substituted udp-galactose 4-epimerase
31% identity, 99% coverage of query (110 bits)
1i3kA / Q14376 Molecular basis for severe epimerase-deficiency galactosemia: x-ray structure of the human v94m-substituted udp-galactose 4-epimerase (see paper)
31% identity, 99% coverage of query (110 bits)
RHM2 / Q9LPG6 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM2 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM2_ARATH / Q9LPG6 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2; NDP-rhamnose synthase; Protein MUCILAGE-MODIFIED 4; Protein RHAMNOSE BIOSYNTHESIS 2; Rhamnose biosynthetic enzyme 2; AtRHM2; UDP-L-rhamnose synthase MUM4; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
27% identity, 99% coverage of query (110 bits)
2c20A / A0A6L8PTV5 Crystal structure of udp-glucose 4-epimerase
29% identity, 91% coverage of query (110 bits)
tyv / P14169 CDP-paratose 2-epimerase (EC 5.1.3.10) from Salmonella typhi (see paper)
RFBE_SALTI / P14169 CDP-paratose 2-epimerase; CDP-tyvelose 2-epimerase; EC 5.1.3.10 from Salmonella typhi (see paper)
30% identity, 78% coverage of query (110 bits)
1orrA / P14169 Crystal structure of cdp-tyvelose 2-epimerase complexed with NAD and cdp (see paper)
30% identity, 78% coverage of query (109 bits)
1kerB / Q8GIP9 The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from streptococcus suis with dtdp-d-glucose bound (see paper)
30% identity, 99% coverage of query (109 bits)
1ketA The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from streptococcus suis with thymidine diphosphate bound
30% identity, 99% coverage of query (108 bits)
1kepA The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from streptococcus suis with dtdp-xylose bound
30% identity, 99% coverage of query (108 bits)
2q1wA / O87987 Crystal structure of the bordetella bronchiseptica enzyme wbmh in complex with NAD+ (see paper)
32% identity, 96% coverage of query (108 bits)
2pzmA / O87988 Crystal structure of the bordetella bronchiseptica enzyme wbmg in complex with NAD and udp (see paper)
31% identity, 84% coverage of query (107 bits)
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