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Searching for up to 100 curated homologs for GFF4616 FitnessBrowser__WCS417:GFF4616 (297 a.a.)

Found high-coverage hits (≥70%) to 13 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

YLL056C / Q12177 NADH-dependent aldehyde reductase (EC 1.1.1.77; EC 1.1.1.244; EC 1.1.1.1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 10 papers)
YL056_YEAST / Q12177 Uncharacterized protein YLL056C from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    31% identity, 99% coverage of query (125 bits)

UCSJ_ACRSP / A0A411KUU5 Oxidase ucsJ; UCS1025A pyrrolizidinone biosynthesis cluster protein J; EC 1.-.-.- from Acremonium sp. (see paper)
    30% identity, 95% coverage of query (101 bits)

Build an alignment

Build an alignment for GFF4616 and 2 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

auaH / H1ZZB0 4-hydroxy-2-methyl-3-oxo-4-farnesyl-3,4-dihydroquinoline-1-oxide 3-reductase (EC 1.1.1.394) from Stigmatella aurantiaca (see 2 papers)
AUAH_STIAU / H1ZZB0 Aurachin B dehydrogenase; EC 1.1.1.394 from Stigmatella aurantiaca (see 2 papers)
H1ZZB0 aurachin B dehydrogenase (EC 1.1.1.394) from Stigmatella aurantiaca (see paper)
    29% identity, 74% coverage of query (82.4 bits)

Q9SZB3 farnesol dehydrogenase (NAD+) (EC 1.1.1.354) from Arabidopsis thaliana (see paper)
    25% identity, 79% coverage of query (67.0 bits)

OLED_STRMK / B2FI29 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Stenotrophomonas maltophilia (strain K279a) (see paper)
B2FI29 2-alkyl-3-oxoalkanoate reductase (EC 1.1.1.412) from Stenotrophomonas maltophilia (see 2 papers)
    27% identity, 75% coverage of query (66.2 bits)

oleD / Q8EG63 hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oate reductase (EC 1.1.1.412) from Shewanella oneidensis (strain MR-1) (see paper)
OLED_SHEON / Q8EG63 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Shewanella oneidensis (strain ATCC 700550 / JCM 31522 / CIP 106686 / LMG 19005 / NCIMB 14063 / MR-1) (see paper)
    26% identity, 74% coverage of query (55.5 bits)

wbiG / GI|3135686 putative epimerase/dehydratase WbiG from Burkholderia pseudomallei (see paper)
    25% identity, 96% coverage of query (54.7 bits)

ORF35x7 / CAA69124.1 ORF35x7 from Vibrio cholerae (see paper)
    22% identity, 95% coverage of query (50.4 bits)

oleD / Q8PDW5 2-alkyl-3-oxo-fatty acid reductase monomer (EC 1.1.1.412) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 2 papers)
OLED_XANCP / Q8PDW5 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 2 papers)
    26% identity, 75% coverage of query (47.4 bits)

RMLB_MYCS2 / A0QSK6 dTDP-glucose 4,6-dehydratase; EC 4.2.1.46 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    22% identity, 99% coverage of query (46.6 bits)

1ketA The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from streptococcus suis with thymidine diphosphate bound
    22% identity, 97% coverage of query (42.7 bits)

1kepA The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from streptococcus suis with dtdp-xylose bound
    22% identity, 97% coverage of query (42.7 bits)

1kerB / Q8GIP9 The crystal structure of dtdp-d-glucose 4,6-dehydratase (rmlb) from streptococcus suis with dtdp-d-glucose bound (see paper)
    22% identity, 97% coverage of query (42.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory