Searching for up to 100 curated homologs for GFF4622 FitnessBrowser__WCS417:GFF4622 (416 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

Removed hits that are identical to the query, leaving 18

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

kyn / P83788 kynureninase subunit (EC 3.7.1.3) from Pseudomonas fluorescens (see 2 papers)
KYNU_PSEFL / P83788 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Pseudomonas fluorescens (see paper)
    86% identity, 100% coverage of query (747 bits)

PfGW456L13_4288 Kynureninase (EC 3.7.1.3) from Pseudomonas fluorescens GW456-L13
    85% identity, 100% coverage of query (740 bits)

1qz9A / P83788 The three dimensional structure of kynureninase from pseudomonas fluorescens (see paper)
    87% identity, 97% coverage of query (729 bits)

AO353_05935 Kynureninase (EC 3.7.1.3) from Pseudomonas fluorescens FW300-N2E3
    84% identity, 100% coverage of query (723 bits)

RR42_RS15385 Kynureninase (EC 3.7.1.3) from Cupriavidus basilensis FW507-4G11
    72% identity, 100% coverage of query (608 bits)

BPHYT_RS16030 Kynureninase (EC 3.7.1.3) from Burkholderia phytofirmans PsJN
    66% identity, 100% coverage of query (569 bits)

acmH / D6R244 3-hydroxy-4-methyl-D-kynurenine hydrolase monomer from Streptomyces anulatus (see 4 papers)
    43% identity, 96% coverage of query (304 bits)

sibQ / C0LTN1 kynureninase (EC 3.7.1.3) from Streptosporangium sibiricum (see paper)
    39% identity, 96% coverage of query (268 bits)

B7XB98 kynureninase (EC 3.7.1.3) from Bombyx mori (see paper)
    34% identity, 98% coverage of query (230 bits)

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Build an alignment for GFF4622 and 9 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

KYNU_MOUSE / Q9CXF0 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Mus musculus (Mouse) (see paper)
    28% identity, 94% coverage of query (160 bits)

Kynu / P70712 kynureninase subunit (EC 3.7.1.3) from Rattus norvegicus (see paper)
KYNU_RAT / P70712 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Rattus norvegicus (Rat) (see paper)
    27% identity, 95% coverage of query (159 bits)

3e9kA Crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex
    28% identity, 94% coverage of query (155 bits)

KYNU_YEAST / Q05979 Kynureninase; Biosynthesis of nicotinic acid protein 5; L-kynurenine hydrolase; EC 3.7.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    29% identity, 94% coverage of query (154 bits)

2hzpA / Q16719 Crystal structure of homo sapiens kynureninase (see paper)
    28% identity, 94% coverage of query (154 bits)

KYNU / Q16719 Kynureninase (EC 3.7.1.3) from Homo sapiens (see 5 papers)
KYNU_HUMAN / Q16719 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Homo sapiens (Human) (see 6 papers)
Q16719 kynureninase (EC 3.7.1.3) from Homo sapiens (see 4 papers)
    28% identity, 94% coverage of query (152 bits)

KYNU_CAEEL / Q18026 Kynureninase; Abnormal fluorescence under UV illumination; L-kynurenine hydrolase; EC 3.7.1.3 from Caenorhabditis elegans (see paper)
    27% identity, 89% coverage of query (144 bits)

8odqD / P9WQ69 Sufs-sufu complex from mycobacterium tuberculosis (see paper)
    24% identity, 89% coverage of query (67.8 bits)

7tlmA / C8W9P2 Structure of atopobium parvulum sufs (see paper)
    23% identity, 70% coverage of query (48.1 bits)

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