Searching for up to 100 curated homologs for GFF499 FitnessBrowser__Phaeo:GFF499 (319 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

A9CGZ4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
    74% identity, 100% coverage of query (481 bits)

lhpC / Q88NF4 Δ¹-pyrroline-4-hydroxy-2-carboxylate deaminase subunit (EC 3.5.4.22) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
    76% identity, 99% coverage of query (479 bits)

2hmcA / A9CGZ4 The crystal structure of dihydrodipicolinate synthase dapa from agrobacterium tumefaciens
    75% identity, 97% coverage of query (477 bits)

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Build an alignment for GFF499 and 3 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

Q8NMD2 N-acetylneuraminate lyase (EC 4.1.3.3) from Corynebacterium glutamicum (see paper)
    29% identity, 71% coverage of query (75.1 bits)

HOGA1_BOVIN / Q0P5I5 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Dihydrodipicolinate synthase-like; DHDPS-like protein; Probable 2-keto-4-hydroxyglutarate aldolase; Probable KHG-aldolase; EC 4.1.3.16 from Bos taurus (Bovine) (see 2 papers)
Q0P5I5 4-Hydroxy-2-oxoglutarate aldolase (EC 4.1.3.16) from Bos taurus (see paper)
    29% identity, 78% coverage of query (73.6 bits)

4fhaA Structure of dihydrodipicolinate synthase from streptococcus pneumoniae,bound to pyruvate and lysine
    27% identity, 73% coverage of query (73.2 bits)

YjhH / b4298 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yjhH / P39359 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli (strain K12) (see 7 papers)
YJHH_ECOLI / P39359 Probable 2-dehydro-3-deoxy-D-pentonate aldolase YjhH; EC 4.1.2.28 from Escherichia coli (strain K12) (see paper)
    26% identity, 78% coverage of query (67.8 bits)

DAPA_NEIMB / Q9JZR4 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Neisseria meningitidis serogroup B (strain MC58) (see paper)
Q9JZR4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Neisseria meningitidis (see paper)
    28% identity, 74% coverage of query (67.4 bits)

dhdps / CAC50571.1 dihydrodipicolinate synthetase from Yersinia enterocolitica (see paper)
    27% identity, 74% coverage of query (60.1 bits)

1o5kA / Q9X1K9 Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
    25% identity, 74% coverage of query (59.7 bits)

DAPA_THEMA / Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
    25% identity, 74% coverage of query (59.7 bits)

CNSN_PENEN / A0A0A2JW93 Communesin biosynthesis cluster-specific transcription factor cnsN; Communesin biosynthesis cluster protein N from Penicillium expansum (Blue mold rot fungus) (see paper)
    26% identity, 74% coverage of query (58.9 bits)

A5F699 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Vibrio cholerae (see paper)
    26% identity, 87% coverage of query (52.4 bits)

4pfmA / A9DKW4 Shewanella benthica dhdps with lysine and pyruvate
    26% identity, 87% coverage of query (52.0 bits)

A9CFV4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
    24% identity, 82% coverage of query (51.6 bits)

8u8wA / A0A0H3FJT8 Crystal structure of n-acetylneuraminate lyase (nana) from klebsiella aerogenes (pyruvate and halides bound)
    27% identity, 82% coverage of query (50.8 bits)

5t25A / B7M7I1 Kinetic, spectral and structural characterization of the slow binding inhibitor acetopyruvate with dihydrodipicolinate synthase from escherichia coli.
    27% identity, 73% coverage of query (49.7 bits)

DapA / b2478 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli K-12 substr. MG1655 (see 24 papers)
dapA / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (strain K12) (see 23 papers)
DAPA_ECOLI / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12) (see 11 papers)
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (see 15 papers)
    27% identity, 73% coverage of query (49.7 bits)

2atsA Dihydrodipicolinate synthase co-crystallised with (s)-lysine
    27% identity, 73% coverage of query (49.7 bits)

3i7sA Dihydrodipicolinate synthase mutant - k161a - with the substrate pyruvate bound in the active site.
    26% identity, 73% coverage of query (48.5 bits)

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