Searching for up to 100 curated homologs for GFF5019 FitnessBrowser__WCS417:GFF5019 (349 a.a.)
Found high-coverage hits (≥70%) to 51 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
P00500 anthranilate synthase (subunit 1/2) (EC 4.1.3.27) from Serratia marcescens (see paper)
61% identity, 99% coverage of query (437 bits)
4yi7A / P00500 Anthranilate bound at active site of anthranilate phosphoribosyl transferase from acinetobacter (anprt; trpd)
58% identity, 98% coverage of query (399 bits)
trpD / BAC65124.1 anthranilate phosphoribosyltransferase from Burkholderia multivorans (see paper)
50% identity, 98% coverage of query (317 bits)
trpD / AAB39009.1 anthranilate phosphoribosyltransferase from Bradyrhizobium japonicum (see paper)
44% identity, 96% coverage of query (281 bits)
TRPD_XANCP / Q8PD71 Anthranilate phosphoribosyltransferase; EC 2.4.2.18 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
47% identity, 97% coverage of query (273 bits)
trpD / AAD09118.1 anthranilate phosphoribosyltransferase from Rhodobacter sphaeroides (see paper)
45% identity, 79% coverage of query (235 bits)
TRPD_SACS2 / P50384 Anthranilate phosphoribosyltransferase; EC 2.4.2.18 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 4 papers)
P50384 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Saccharolobus solfataricus (see 7 papers)
2gvqD / P50384 Anthranilate phosphoribosyl-transferase (trpd) from s. Solfataricus in complex with anthranilate (see paper)
37% identity, 96% coverage of query (214 bits)
1zxyA Anthranilate phosphoribosyltransferase from sulfolobus solfataricus in complex with prpp and magnesium
37% identity, 96% coverage of query (214 bits)
1kgzB / Q8VP84 Crystal structure analysis of the anthranilate phosphoribosyltransferase from erwinia carotovora (current name, pectobacterium carotovorum) (see paper)
37% identity, 95% coverage of query (204 bits)
1gxbA Anthranilate phosphoribosyltransferase in complex with pyrophosphate and magnesium
36% identity, 96% coverage of query (200 bits)
Q9YGB4 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Thermococcus kodakarensis (see paper)
5nofA / Q9YGB4 Anthranilate phosphoribosyltransferase from thermococcus kodakaraensis (see paper)
38% identity, 96% coverage of query (199 bits)
TrpD / b1263 anthranilate synthase subunit TrpD (EC 2.4.2.18; EC 4.1.3.27) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
trpD / P00904 anthranilate synthase subunit TrpD (EC 2.4.2.18) from Escherichia coli (strain K12) (see 2 papers)
TRPGD_ECOLI / P00904 Bifunctional protein TrpGD; EC 4.1.3.27; EC 2.4.2.18 from Escherichia coli (strain K12) (see 3 papers)
40% identity, 81% coverage of query (184 bits)
TRPGD_SALTY / P00905 Bifunctional protein TrpGD; EC 4.1.3.27; EC 2.4.2.18 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
38% identity, 96% coverage of query (184 bits)
3gbrA Anthranilate phosphoribosyl-transferase (trpd) double mutant d83g f149s from s. Solfataricus
36% identity, 96% coverage of query (183 bits)
TRPD_THETH / P83827 Anthranilate phosphoribosyltransferase; EC 2.4.2.18 from Thermus thermophilus
TRPD_THET8 / Q5SH88 Anthranilate phosphoribosyltransferase; EC 2.4.2.18 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
42% identity, 91% coverage of query (179 bits)
TRPD2_NOSS1 / Q8YXQ9 Anthranilate phosphoribosyltransferase 2; EC 2.4.2.18 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
33% identity, 95% coverage of query (179 bits)
TRPD_MYCTU / P9WFX5 Anthranilate phosphoribosyltransferase; EC 2.4.2.18 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
A5U4M0 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Mycobacterium tuberculosis (see paper)
P9WFX5 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Mycobacterium tuberculosis (see 3 papers)
38% identity, 95% coverage of query (174 bits)
3r88B Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor acs145)
39% identity, 95% coverage of query (174 bits)
5c1rA Stereoisomer of prpp bound in the active site of mycobacterium tuberculosis anthranilate phosphoribosyl (anprt; trpd)
39% identity, 95% coverage of query (174 bits)
4n5vA Alternative substrates of mycobacterium tuberculosis anthranilate phosphoribosyl transferase
39% identity, 95% coverage of query (174 bits)
4n93A Alternative substrates of mycobacterium tuberculosis anthranilate phosphoribosyl transferase
39% identity, 95% coverage of query (174 bits)
4zokA Methylsulfonyl-containing inhibitor bound in the substrate capture site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
38% identity, 95% coverage of query (174 bits)
4zofA Lobenzarit-like inhibitor bound in the active site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
38% identity, 95% coverage of query (174 bits)
4owoA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 6-fluoroanthranilate, prpp and magnesium
38% identity, 95% coverage of query (174 bits)
5c2lA / P9WFX5 Magnesium soaked into the active site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
38% identity, 95% coverage of query (173 bits)
4owmA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 3-fluoroanthranilate, prpp and magnesium
38% identity, 95% coverage of query (173 bits)
4gkmA Bianthranilate-like analogue bound in the outer site of anthranilate phosphoribosyltransferase (anprt; trpd)
38% identity, 95% coverage of query (173 bits)
3r6cA Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor acs179)
38% identity, 95% coverage of query (173 bits)
3qsaA Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor tamu-a7)
38% identity, 95% coverage of query (173 bits)
3qs8A Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor acs174)
38% identity, 95% coverage of query (173 bits)
3qqsA Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor acs172)
38% identity, 95% coverage of query (173 bits)
1zvwA The crystal structure of trpd (rv2192c) from mycobacterium tuberculosis in complex with prpp and magnesium
38% identity, 95% coverage of query (173 bits)
4giuA Bianthranilate-like analogue bound in inner site of anthranilate phosphoribosyltransferase (anprt; trpd).
38% identity, 95% coverage of query (173 bits)
4owuA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 5-methylanthranilate, prpp and magnesium
38% identity, 95% coverage of query (173 bits)
4owqA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 3-methylanthranilate, prpp and magnesium
38% identity, 95% coverage of query (173 bits)
5c7sA Prpp complexed with two mn2+ in the active site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
38% identity, 95% coverage of query (173 bits)
4zojA Methylsulfanyl-containing inhibitor bound in the active site of mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
39% identity, 95% coverage of query (173 bits)
BT0530 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Bacteroides thetaiotaomicron VPI-5482
32% identity, 96% coverage of query (169 bits)
4ownA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 5-fluoroanthranilate, prpp and magnesium
38% identity, 95% coverage of query (168 bits)
3uu1A Anthranilate phosphoribosyltransferase (trpd) from mycobacterium tuberculosis (complex with inhibitor acs142)
39% identity, 95% coverage of query (167 bits)
CA265_RS05010 anthranilate phosphoribosyltransferase (EC 2.4.2.18) from Pedobacter sp. GW460-11-11-14-LB5
36% identity, 81% coverage of query (163 bits)
4m0rA Trianthranilate-like analogue bound to anthranilate phosphoribosyltransferase (anprt; trpd).
38% identity, 95% coverage of query (161 bits)
4owsA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with 4-methylanthranilate, prpp and magnesium
37% identity, 95% coverage of query (155 bits)
4owvA Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with anthranilate
37% identity, 95% coverage of query (152 bits)
5bneA Bianthranilate-like inhibitor with 6 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
37% identity, 95% coverage of query (152 bits)
5bo3B Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
36% identity, 95% coverage of query (149 bits)
5bo2A Bianthranilate-like inhibitor with 4-atom "line" and phosphonate "hook" fishing for hydrogen bond donors in mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
36% identity, 95% coverage of query (148 bits)
5bo3A Bianthranilate-like inhibitor with 5 atom "line" and phosphonate "hook" fishing for hydrogen bond donors in mycobacterium tuberculosis anthranilate phosphoribosyltransferase (anprt; trpd)
36% identity, 95% coverage of query (143 bits)
TRPD_YEAST / P07285 Anthranilate phosphoribosyltransferase; PRtransferase; EC 2.4.2.18 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
30% identity, 86% coverage of query (121 bits)
7dsjA / P07285 Anthranilate phosphoribosyltransferase from saccharomyces cerevisiae in complex with prpp and mg (see paper)
30% identity, 86% coverage of query (120 bits)
Build an alignment for GFF5019 and 50 homologs with ≥ 30% identity
Or download the sequences
7dsoA Anthranilate phosphoribosyltransferase from saccharomyces cerevisiae in complex with 4-fluoroanthranilate
29% identity, 86% coverage of query (112 bits)
Or start over
Lawrence Berkeley National Laboratory