Searching for up to 100 curated homologs for GFF503 FitnessBrowser__psRCH2:GFF503 (421 a.a.)

Found high-coverage hits (≥70%) to 15 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ProA / b0243 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
proA / P07004 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Escherichia coli (strain K12) (see 27 papers)
PROA_ECOLI / P07004 Gamma-glutamyl phosphate reductase; GPR; Glutamate-5-semialdehyde dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase; GSA dehydrogenase; EC 1.2.1.41 from Escherichia coli (strain K12) (see 3 papers)
    46% identity, 98% coverage of query (376 bits)

A7Y114 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Halobacillus halophilus (see paper)
    47% identity, 96% coverage of query (357 bits)

PROA_YEAST / P54885 Gamma-glutamyl phosphate reductase; GPR; Glutamate-5-semialdehyde dehydrogenase; GSA dehydrogenase; Glutamyl-gamma-semialdehyde dehydrogenase; EC 1.2.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    39% identity, 97% coverage of query (306 bits)

P5CS1 / P54887 δ1-pyrroline-5-carboxylate synthetase (EC 1.2.1.41; EC 2.7.2.11) from Arabidopsis thaliana (see 4 papers)
    40% identity, 96% coverage of query (295 bits)

P5CS1_ORYSJ / O04226 Delta-1-pyrroline-5-carboxylate synthase 1; OsP5CS1; EC 2.7.2.11; EC 1.2.1.41 from Oryza sativa subsp. japonica (Rice) (see paper)
    38% identity, 100% coverage of query (278 bits)

7wxgA / Q9VNW6 Gpr domain closed form of drosophila p5cs filament with glutamate, atp, and NADPH (see paper)
    39% identity, 97% coverage of query (277 bits)

7wxiA Gpr domain of drosophila p5cs filament with glutamate and atpgammas
    39% identity, 97% coverage of query (277 bits)

P5CS2_ORYSJ / Q941T1 Delta-1-pyrroline-5-carboxylate synthase 2; OsP5CS2; EC 2.7.2.11; EC 1.2.1.41 from Oryza sativa subsp. japonica (Rice)
Q941T1 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Oryza sativa (see paper)
    38% identity, 96% coverage of query (275 bits)

ALDH18A1 / P54886 δ-1-pyrroline-5-carboxylate synthase (EC 1.2.1.41; EC 2.7.2.11) from Homo sapiens (see 4 papers)
P5CS_HUMAN / P54886 Delta-1-pyrroline-5-carboxylate synthase; P5CS; Aldehyde dehydrogenase family 18 member A1; EC 2.7.2.11; EC 1.2.1.41 from Homo sapiens (Human) (see 8 papers)
    39% identity, 97% coverage of query (275 bits)

P5CS_MOUSE / Q9Z110 Delta-1-pyrroline-5-carboxylate synthase; P5CS; Aldehyde dehydrogenase family 18 member A1; EC 2.7.2.11; EC 1.2.1.41 from Mus musculus (Mouse) (see paper)
Q9Z110 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) from Mus musculus (see paper)
    39% identity, 97% coverage of query (272 bits)

p5cs / CAB40834.1 pyrroline-5-carboxylate synthetase from Vitis vinifera (see paper)
    38% identity, 96% coverage of query (270 bits)

Echvi_2633 gamma-glutamylphosphate reductase (EC 1.2.1.41) from Echinicola vietnamensis KMM 6221, DSM 17526
    38% identity, 94% coverage of query (248 bits)

4jbeB / C7MW73 1.95 angstrom crystal structure of gamma-glutamyl phosphate reductase from saccharomonospora viridis.
    31% identity, 98% coverage of query (166 bits)

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Build an alignment for GFF503 and 13 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

5j7iB Crystal structure of a geobacillus thermoglucosidasius acetylating aldehyde dehydrogenase in complex with adp (see paper)
    24% identity, 78% coverage of query (57.4 bits)

5j7iC Crystal structure of a geobacillus thermoglucosidasius acetylating aldehyde dehydrogenase in complex with adp
    24% identity, 78% coverage of query (57.4 bits)

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