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Searching for up to 100 curated homologs for GFF5058 FitnessBrowser__WCS417:GFF5058 (560 a.a.)

Found high-coverage hits (≥70%) to 38 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PfGW456L13_1171 Lysine 2-monooxygenase (EC 1.13.12.2) from Pseudomonas fluorescens GW456-L13
    95% identity, 100% coverage of query (1108 bits)

AO353_07420 Lysine 2-monooxygenase (EC 1.13.12.2) from Pseudomonas fluorescens FW300-N2E3
    94% identity, 100% coverage of query (1105 bits)

Pf1N1B4_2505 Lysine 2-monooxygenase (EC 1.13.12.2) from Pseudomonas fluorescens FW300-N1B4
    94% identity, 100% coverage of query (1102 bits)

AO356_14230 lysine 2-monooxygenase (EC 1.13.12.2) from Pseudomonas fluorescens FW300-N2C3
    93% identity, 100% coverage of query (1081 bits)

Pf6N2E2_4778 Lysine 2-monooxygenase (EC 1.13.12.2) from Pseudomonas fluorescens FW300-N2E2
    93% identity, 100% coverage of query (1079 bits)

W6JQJ6 lysine 2-monooxygenase (EC 1.13.12.2); L-amino-acid oxidase (EC 1.4.3.2) from Pseudomonas sp. AIU 813 (see 2 papers)
    91% identity, 100% coverage of query (1065 bits)

davB / B3IVI6 L-lysine monooxygenase monomer (EC 1.13.12.2) from Pseudomonas putida (see 6 papers)
    90% identity, 100% coverage of query (1061 bits)

5yb6A / W6JQJ6 L-amino acid oxidase/monooxygenase from pseudomonas sp. Aiu 813 - l- lysine complex (see paper)
    91% identity, 99% coverage of query (1060 bits)

Q88QV1 lysine 2-monooxygenase (EC 1.13.12.2) from Pseudomonas putida (see 2 papers)
    90% identity, 100% coverage of query (1058 bits)

5yb8A L-amino acid oxidase/monooxygenase from pseudomonas sp. Aiu 813 - l- arginine complex
    91% identity, 98% coverage of query (1044 bits)

5yb7A L-amino acid oxidase/monooxygenase from pseudomonas sp. Aiu 813 - l- ornithine complex
    91% identity, 98% coverage of query (1044 bits)

SGR_6070 / B1W482 arginine 2-monooxygenase monomer (EC 1.13.12.1) from Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350) (see 3 papers)
    58% identity, 99% coverage of query (715 bits)

iaaM / P06617 tryptophan 2-monooxygenase (EC 1.13.12.3) from Pseudomonas savastanoi (see 3 papers)
TR2M_PSESS / P06617 Tryptophan 2-monooxygenase; EC 1.13.12.3 from Pseudomonas savastanoi (Pseudomonas syringae pv. savastanoi) (see paper)
P06617 tryptophan 2-monooxygenase (EC 1.13.12.3) from Pseudomonas savastanoi (see paper)
    31% identity, 92% coverage of query (207 bits)

4iv9A / P06617 Structure of the flavoprotein tryptophan-2-monooxygenase (see paper)
    31% identity, 92% coverage of query (207 bits)

Build an alignment

Build an alignment for GFF5058 and 14 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q9R717 tryptophan 2-monooxygenase (EC 1.13.12.3) from Agrobacterium tumefaciens (see paper)
    29% identity, 93% coverage of query (201 bits)

tms1 / P0A3V3 tryptophan 2'-monooxygenase (EC 1.13.12.3) from Rhizobium radiobacter (see paper)
    30% identity, 93% coverage of query (188 bits)

E3KNM7 tryptophan 2-monooxygenase (EC 1.13.12.3) from Puccinia graminis f. sp. tritici (see paper)
    24% identity, 93% coverage of query (132 bits)

OXLA_SIGCA / P86810 L-amino-acid oxidase; Antiparasitic protein; APP; Serum L-amino-acid oxidase; SR-LAAO; EC 1.4.3.2 from Siganus canaliculatus (White-spotted spinefoot) (Chaetodon canaliculatus) (see 2 papers)
P86810 L-amino-acid oxidase (EC 1.4.3.2) from Siganus canaliculatus (see 2 papers)
    25% identity, 89% coverage of query (91.3 bits)

D2KWB6 L-amino-acid oxidase (EC 1.4.3.2) from Platichthys stellatus (see 3 papers)
    24% identity, 87% coverage of query (82.0 bits)

OXLA_ECHOC / B5U6Y8 L-amino-acid oxidase; LAAO; LAO; EC 1.4.3.2 from Echis ocellatus (Ocellated saw-scaled viper) (see paper)
    24% identity, 86% coverage of query (80.1 bits)

OXLA_OPHHA / P81383 L-amino-acid oxidase; LAO; Oh-LAAO; EC 1.4.3.2 from Ophiophagus hannah (King cobra) (Naja hannah) (see 7 papers)
P81383 L-amino-acid oxidase (EC 1.4.3.2) from Ophiophagus hannah (see paper)
    23% identity, 90% coverage of query (78.2 bits)

OXLA_DABRR / G8XQX1 L-amino-acid oxidase; DrLAO; LAAO; EC 1.4.3.2 from Daboia russelii (Russel's viper) (Vipera russelii) (see paper)
G8XQX1 L-amino-acid oxidase (EC 1.4.3.2) from Daboia russelii (see paper)
    25% identity, 93% coverage of query (77.0 bits)

OXLA_VIPAA / P0DI84 L-amino-acid oxidase; LAO; VAA-LAAO I; EC 1.4.3.2 from Vipera ammodytes ammodytes (Western sand viper) (see 2 papers)
3kveA / P0DI84 Structure of native l-amino acid oxidase from vipera ammodytes ammodytes: stabilization of the quaternary structure by divalent ions and structural changes in the dynamic active site
    24% identity, 88% coverage of query (73.9 bits)

OXLA_GLOBL / Q90W54 L-amino-acid oxidase; LAAO; M-LAO; EC 1.4.3.2 from Gloydius blomhoffii (Mamushi) (Agkistrodon halys blomhoffi) (see 2 papers)
Q90W54 L-amino-acid oxidase (EC 1.4.3.2) from Gloydius blomhoffii (see paper)
    24% identity, 88% coverage of query (69.7 bits)

OXLA_BOTPA / B5AR80 L-amino-acid oxidase; Bp-LAAO; LAO; EC 1.4.3.2 from Bothrops pauloensis (Neuwied's lancehead) (Bothrops neuwiedi pauloensis) (see paper)
    22% identity, 90% coverage of query (68.2 bits)

1reoA / Q6STF1 L-amino acid oxidase from agkistrodon halys pallas (see paper)
    23% identity, 88% coverage of query (66.6 bits)

OXLA_GLOHA / Q6STF1 L-amino-acid oxidase; AHP-LAAO; LAO; EC 1.4.3.2 from Gloydius halys (Chinese water mocassin) (Agkistrodon halys) (see paper)
    23% identity, 88% coverage of query (66.6 bits)

OXLA1_BOTJR / Q6TGQ9 L-amino-acid oxidase BjussuLAAO-I; BjsuLAAO; LAO; EC 1.4.3.2 from Bothrops jararacussu (Jararacussu) (see 2 papers)
    22% identity, 87% coverage of query (66.6 bits)

1tdoA L-amino acid oxidae from agkistrodon halys in complex with l- phenylalanine
    23% identity, 88% coverage of query (66.6 bits)

1tdnA L-amino acid oxidase from agkistrodon halys in complex with l-leucine
    23% identity, 88% coverage of query (66.6 bits)

1tdkA L-amino acid oxidase from agkistrodon halys in complex with suicide substrate l-vinylglycine
    23% identity, 88% coverage of query (66.6 bits)

OXLA_CRODM / K9N7B7 L-amino acid oxidase Cdc18; CdcLAAO; LAO; EC 1.4.3.2 from Crotalus durissus cumanensis (South American rattlesnake) (see 2 papers)
    21% identity, 86% coverage of query (62.8 bits)

OXLA_CRODU / C0HJE7 L-amino acid oxidase bordonein-L; LAAO; LAO; EC 1.4.3.2 from Crotalus durissus terrificus (South American rattlesnake) (see 2 papers)
C0HJE7 L-amino-acid oxidase (EC 1.4.3.2) from Crotalus durissus terrificus (see paper)
    21% identity, 86% coverage of query (62.8 bits)

OXLAA_CERCE / X2JCV5 L-amino acid oxidase; CC-LAAO; LAO; EC 1.4.3.2 from Cerastes cerastes (Horned desert viper) (see 2 papers)
    22% identity, 86% coverage of query (58.2 bits)

OXLA_PSEAU / Q4JHE1 L-amino-acid oxidase; LAAO; LAO; EC 1.4.3.2 from Pseudechis australis (Mulga snake) (King brown snake) (see paper)
    22% identity, 86% coverage of query (56.6 bits)

A8QL51 L-amino-acid oxidase (EC 1.4.3.2) from Bungarus multicinctus (see 2 papers)
    22% identity, 88% coverage of query (54.7 bits)

5z2gA / A8QL58 Crystal structure of l-amino acid oxidase from venom of naja atra
    21% identity, 90% coverage of query (53.5 bits)

OXLA_NAJAT / A8QL58 L-amino-acid oxidase; LAO; NA-LAAO; EC 1.4.3.2 from Naja atra (Chinese cobra) (see paper)
    21% identity, 90% coverage of query (53.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory