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Searching for up to 100 curated homologs for GFF5160 FitnessBrowser__WCS417:GFF5160 (387 a.a.)

Found high-coverage hits (≥70%) to 62 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q9RBS3 phosphoglycerate kinase (EC 2.7.2.3) from Pseudomonas sp. TACII 18 (see paper)
    95% identity, 100% coverage of query (709 bits)

Pgk / b2926 phosphoglycerate kinase (EC 2.7.2.3) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
pgk / P0A799 phosphoglycerate kinase (EC 2.7.2.3) from Escherichia coli (strain K12) (see 19 papers)
P0A799 phosphoglycerate kinase (EC 2.7.2.3) from Escherichia coli (see 2 papers)
    70% identity, 100% coverage of query (543 bits)

P0A799 Phosphoglycerate kinase; EC 2.7.2.3 from Escherichia coli (strain K12)
    70% identity, 100% coverage of query (543 bits)

1zmrA / P0A799 Crystal structure of the e. Coli phosphoglycerate kinase (see paper)
    70% identity, 99% coverage of query (541 bits)

Q4JDI4 phosphoglycerate kinase (EC 2.7.2.3) from Nitrosospira multiformis (see paper)
    62% identity, 100% coverage of query (482 bits)

4feyA / Q5NF76 An x-ray structure of a putative phosphogylcerate kinase with bound adp from francisella tularensis subsp. Tularensis schu s4
    61% identity, 99% coverage of query (475 bits)

4ng4B / Q83AU6 Structure of phosphoglycerate kinase (cbu_1782) from coxiella burnetii (see paper)
    57% identity, 99% coverage of query (457 bits)

P40924 Phosphoglycerate kinase; EC 2.7.2.3 from Bacillus subtilis (strain 168)
    46% identity, 99% coverage of query (329 bits)

pgk / P36204 Pgk (EC 2.7.2.3; EC 5.3.1.1) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 4 papers)
PGKT_THEMA / P36204 Bifunctional PGK/TIM; EC 2.7.2.3; EC 5.3.1.1 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 3 papers)
P36204 triose-phosphate isomerase (EC 5.3.1.1) from Thermotoga maritima (see 2 papers)
    46% identity, 98% coverage of query (325 bits)

1vpeA / P36204 Crystallographic analysis of phosphoglycerate kinase from the hyperthermophilic bacterium thermotoga maritima (see paper)
    47% identity, 97% coverage of query (325 bits)

PGK_GEOSE / P18912 Phosphoglycerate kinase; EC 2.7.2.3 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 2 papers)
1phpA / P18912 Structure of the adp complex of the 3-phosphoglycerate kinase from bacillus stearothermophilus at 1.65 angstroms (see paper)
    45% identity, 99% coverage of query (322 bits)

Q6H6C7 phosphoglycerate kinase (EC 2.7.2.3) from Oryza sativa (see paper)
    49% identity, 96% coverage of query (322 bits)

PGKY3_ARATH / Q9SAJ4 Phosphoglycerate kinase 3, cytosolic; EC 2.7.2.3 from Arabidopsis thaliana (Mouse-ear cress) (see 7 papers)
    48% identity, 97% coverage of query (321 bits)

A0A1D3TPD1 phosphoglycerate kinase (EC 2.7.2.3) from Anaerobium acetethylicum (see paper)
    44% identity, 96% coverage of query (317 bits)

PGKH1_ARATH / Q9LD57 Phosphoglycerate kinase 1, chloroplastic; EC 2.7.2.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9LD57 phosphoglycerate kinase (EC 2.7.2.3) from Arabidopsis thaliana (see paper)
    47% identity, 97% coverage of query (315 bits)

P50318 phosphoglycerate kinase (EC 2.7.2.3) from Arabidopsis thaliana (see paper)
    46% identity, 97% coverage of query (315 bits)

Q42961 phosphoglycerate kinase (EC 2.7.2.3) from Nicotiana benthamiana (see paper)
    46% identity, 97% coverage of query (310 bits)

A8JC04 phosphoglycerate kinase (EC 2.7.2.3) from Chlamydomonas reinhardtii (see paper)
    46% identity, 97% coverage of query (310 bits)

E5LLE7 phosphoglycerate kinase (EC 2.7.2.3) from Nicotiana benthamiana (see paper)
    46% identity, 97% coverage of query (308 bits)

PGK_NOSS1 / Q8YPR1 Phosphoglycerate kinase; EC 2.7.2.3 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
    46% identity, 98% coverage of query (308 bits)

pgk / AAA62185.1 phosphoglycerate kinase from Xanthobacter flavus (see paper)
    45% identity, 97% coverage of query (306 bits)

c1PGK / AAC37222.1 phosphoglycerate kinase from Trypanosoma congolense (see paper)
c2PGK / AAC37225.1 phosphoglycerate kinase from Trypanosoma congolense (see paper)
    41% identity, 98% coverage of query (292 bits)

P09403 phosphoglycerate kinase (EC 2.7.2.3) from Thermus thermophilus (see paper)
    44% identity, 97% coverage of query (288 bits)

A0A061J5A1 phosphoglycerate kinase (EC 2.7.2.3) from Trypanosoma rangeli (see 2 papers)
    40% identity, 97% coverage of query (286 bits)

Q4D193 phosphoglycerate kinase (EC 2.7.2.3) from Trypanosoma cruzi (see paper)
    42% identity, 97% coverage of query (285 bits)

pgk / O32756 phosphoglycerate kinase subunit (EC 2.7.2.3) from Lactobacillus delbrueckii subsp. bulgaricus (see paper)
    42% identity, 98% coverage of query (284 bits)

PGKC_TRYBB / P07378 Phosphoglycerate kinase, glycosomal; Phosphoglycerate kinase C; EC 2.7.2.3 from Trypanosoma brucei brucei (see paper)
P07378 phosphoglycerate kinase (EC 2.7.2.3) from Trypanosoma brucei brucei (see paper)
    41% identity, 98% coverage of query (281 bits)

13pkA / P07378 Ternary complex of phosphoglycerate kinase from trypanosoma brucei (see paper)
    41% identity, 98% coverage of query (281 bits)

16pkA Phosphoglycerate kinase from trypanosoma brucei bisubstrate analog
    41% identity, 98% coverage of query (281 bits)

PGK_SCHMA / P41759 Phosphoglycerate kinase; PGK; EC 2.7.2.3 from Schistosoma mansoni (Blood fluke) (see paper)
    42% identity, 98% coverage of query (279 bits)

A0A0H5S3P5 phosphoglycerate kinase (EC 2.7.2.3) from Brugia malayi (see 2 papers)
A0A4E9EYJ5 phosphoglycerate kinase (EC 2.7.2.3) from Brugia malayi (see paper)
    42% identity, 98% coverage of query (277 bits)

P07377 phosphoglycerate kinase (EC 2.7.2.3) from Trypanosoma brucei brucei (see paper)
    39% identity, 98% coverage of query (276 bits)

PGK_STRR6 / Q8DQX8 Phosphoglycerate kinase; EC 2.7.2.3 from Streptococcus pneumoniae (strain ATCC BAA-255 / R6) (see paper)
3zlbA / Q04LZ5 Crystal structure of phosphoglycerate kinase from streptococcus pneumoniae (see paper)
    43% identity, 99% coverage of query (274 bits)

C1LT16 phosphoglycerate kinase (EC 2.7.2.3) from Schistosoma japonicum (see paper)
    42% identity, 98% coverage of query (274 bits)

Q01655 phosphoglycerate kinase (EC 2.7.2.3) from Corynebacterium glutamicum (see paper)
    42% identity, 98% coverage of query (274 bits)

O60101 Phosphoglycerate kinase; EC 2.7.2.3 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
    43% identity, 99% coverage of query (272 bits)

PGK2_PIG / Q6RI85 Phosphoglycerate kinase 2; Phosphoglycerate kinase, testis specific; EC 2.7.2.3 from Sus scrofa (Pig) (see paper)
Q6RI85 phosphoglycerate kinase (EC 2.7.2.3) from Sus scrofa (see paper)
    39% identity, 98% coverage of query (270 bits)

2wzcA The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with adp, 3pg and aluminium tetrafluoride
    39% identity, 98% coverage of query (266 bits)

2wzbA The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with adp, 3pg and magnesium trifluoride
    39% identity, 98% coverage of query (266 bits)

Q27683 phosphoglycerate kinase (EC 2.7.2.3) from Leishmania major (see 2 papers)
    39% identity, 99% coverage of query (265 bits)

2wzdA The catalytically active fully closed conformation of human phosphoglycerate kinase k219a mutant in complex with adp, 3pg and aluminium trifluoride
    39% identity, 98% coverage of query (264 bits)

2x15A The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with adp and 1,3- bisphosphoglycerate
    39% identity, 98% coverage of query (264 bits)

4axxA The catalytically active fully closed conformation of human phosphoglycerate kinase in complex with adp 3-phosphoglycerate and beryllium trifluoride
    39% identity, 98% coverage of query (263 bits)

2y3iA The structure of the fully closed conformation of human pgk in complex with l-adp, 3pg and the tsa aluminium tetrafluoride
    38% identity, 98% coverage of query (261 bits)

PGK1 / P00558 phosphoglycerate kinase 1 (EC 2.7.2.3) from Homo sapiens (see 4 papers)
PGK1_HUMAN / P00558 Phosphoglycerate kinase 1; Cell migration-inducing gene 10 protein; Primer recognition protein 2; PRP 2; EC 2.7.2.3 from Homo sapiens (Human) (see 14 papers)
    38% identity, 98% coverage of query (261 bits)

PGK_YEAST / P00560 Phosphoglycerate kinase; EC 2.7.2.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
    41% identity, 98% coverage of query (260 bits)

1kf0A Crystal structure of pig muscle phosphoglycerate kinase ternary complex with amp-pcp and 3pg
    38% identity, 98% coverage of query (260 bits)

1vjcA Structure of pig muscle pgk complexed with mgatp
    39% identity, 98% coverage of query (260 bits)

4o33A / P00558 Crystal structure of human pgk1 3pg and terazosin(tzn) ternary complex (see paper)
    38% identity, 98% coverage of query (259 bits)

1qpgA 3-phosphoglycerate kinase, mutation r65q
    41% identity, 98% coverage of query (258 bits)

5m1rA X-ray structure of human g166d pgk-1 mutant
    38% identity, 98% coverage of query (258 bits)

PGK1_PIG / Q7SIB7 Phosphoglycerate kinase 1; EC 2.7.2.3 from Sus scrofa (Pig) (see 2 papers)
    38% identity, 98% coverage of query (256 bits)

3pgkA / P00560 The structure of yeast phosphoglycerate kinase at 0.25 nm resolution (see paper)
    41% identity, 98% coverage of query (255 bits)

PGK2_MOUSE / P09041 Phosphoglycerate kinase 2; Phosphoglycerate kinase, testis specific; EC 2.7.2.3 from Mus musculus (Mouse) (see 3 papers)
P09041 phosphoglycerate kinase (EC 2.7.2.3) from Mus musculus (see 2 papers)
    38% identity, 98% coverage of query (255 bits)

2paaA / P09041 Crystal structure of phosphoglycerate kinase-2 bound to atp and 3pg (see paper)
    38% identity, 98% coverage of query (253 bits)

1hdiA Pig muscle 3-phosphoglycerate kinase complexed with 3-pg and mgadp.
    38% identity, 98% coverage of query (251 bits)

5np8A Pgk1 in complex with crt0063465 (3-[2-(4-bromophenyl)-5,7-dimethyl- pyrazolo[1,5-a]pyrimidin-6-yl]propanoic acid)
    37% identity, 98% coverage of query (249 bits)

6yjeA / A5K6T9 Plasmoodium vivax phosphoglycerate kinase bound to nitrofuran inhibitor from peg3350 and ammonium acetate at ph 5.5
    36% identity, 98% coverage of query (245 bits)

3c3bA Crystal structure of human phosphoglycerate kinase bound to d-cdp
    37% identity, 98% coverage of query (243 bits)

3c3bB Crystal structure of human phosphoglycerate kinase bound to d-cdp
    37% identity, 98% coverage of query (243 bits)

1ltkC / P27362 Crystal structure of phosphoglycerate kinase from plasmodium falciparum, in the open conformation
    35% identity, 98% coverage of query (238 bits)

O58965 Phosphoglycerate kinase; EC 2.7.2.3 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
    34% identity, 98% coverage of query (207 bits)

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Build an alignment for GFF5160 and 62 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory