Searching for up to 100 curated homologs for GFF53 FitnessBrowser__Marino:GFF53 (383 a.a.)
Found high-coverage hits (≥70%) to 64 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
pimC / Q6N3I0 pimeloyl-CoA dehydrogenase large subunit (EC 1.3.1.62) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) (see paper)
33% identity, 95% coverage of query (178 bits)
CHSE3_MYCTU / P96855 Acyl-CoA dehydrogenase FadE34; ACAD; 3-oxochol-4-en-24-oyl-CoA dehydrogenase; EC 1.3.99.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
33% identity, 86% coverage of query (148 bits)
chsE2 / P71858 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA dehydrogenase β subunit from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
CHSE2_MYCTU / P71858 Acyl-CoA dehydrogenase FadE29; ACAD; 3-oxo-23,24-bisnorchol-4-en-22-oyl-CoA dehydrogenase beta subunit; 3-oxo-4-pregnene-20-carboxyl-CoA dehydrogenase beta subunit; EC 1.3.99.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
32% identity, 85% coverage of query (148 bits)
IPDE1_MYCS2 / A0R4Z9 Acyl-CoA dehydrogenase IpdE1; 5OH-HIP-CoA dehydrogenase alpha subunit; EC 1.3.99.- from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
30% identity, 96% coverage of query (147 bits)
Build an alignment for GFF53 and 4 homologs with ≥ 30% identity
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8hk0B / A0A1W5T3Z2 Crystal structure of fic32-33 complex from streptomyces ficellus nrrl 8067 (see paper)
29% identity, 95% coverage of query (141 bits)
ACD17_MYCTU / P95280 Putative acyl-CoA dehydrogenase FadE17; EC 1.3.99.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
32% identity, 81% coverage of query (139 bits)
4x28A / I6YCA3 Crystal structure of the chse4-chse5 complex from mycobacterium tuberculosis (see paper)
29% identity, 97% coverage of query (135 bits)
6wy9A Tcur3481-tcur3483 steroid acad g363a variant
28% identity, 87% coverage of query (134 bits)
6wy8B / D1AB78 Tcur3481-tcur3483 steroid acad (see paper)
28% identity, 87% coverage of query (133 bits)
ChsE4 / I6YCA3 3-oxocholest-4-en-26-oyl-CoA dehydrogenase α subunit from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
CHSE4_MYCTU / I6YCA3 Acyl-CoA dehydrogenase FadE26; ACAD; 3-oxocholest-4-en-26-oyl-CoA dehydrogenase alpha subunit; EC 1.3.99.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
28% identity, 97% coverage of query (130 bits)
AO356_01580 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) from Pseudomonas fluorescens FW300-N2C3
27% identity, 97% coverage of query (122 bits)
Pf6N2E2_2191 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) from Pseudomonas fluorescens FW300-N2E2
27% identity, 97% coverage of query (122 bits)
Psest_1084 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) from Pseudomonas stutzeri RCH2
27% identity, 97% coverage of query (121 bits)
ivd1 / CAC08233.1 isovaleryl-CoA dehydrogenase from Solanum tuberosum (see paper)
26% identity, 95% coverage of query (120 bits)
liuA / Q9I296 isovaleryl-CoA dehydrogenase subunit (EC 1.3.8.4) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
27% identity, 97% coverage of query (119 bits)
ACADL_MOUSE / P51174 Long-chain specific acyl-CoA dehydrogenase, mitochondrial; LCAD; EC 1.3.8.8 from Mus musculus (Mouse) (see 2 papers)
P51174 long-chain acyl-CoA dehydrogenase (EC 1.3.8.8) from Mus musculus (see paper)
28% identity, 95% coverage of query (119 bits)
MBCD_SOLTU / Q9FS88 2-methylacyl-CoA dehydrogenase, mitochondrial; 2-methylbutanoyl-CoA dehydrogenase; 2-methylbutyryl-CoA dehydrogenase; 2MBCD; Isovaleryl-CoA dehydrogenase 1; St-IVD1; EC 1.3.8.5 from Solanum tuberosum (Potato) (see 2 papers)
25% identity, 95% coverage of query (118 bits)
AO353_20350 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) from Pseudomonas fluorescens FW300-N2E3
27% identity, 97% coverage of query (118 bits)
ACADL_RAT / P15650 Long-chain specific acyl-CoA dehydrogenase, mitochondrial; LCAD; EC 1.3.8.8 from Rattus norvegicus (Rat) (see 3 papers)
28% identity, 95% coverage of query (117 bits)
ACDC_MYCTU / P9WQG3 Acyl-CoA dehydrogenase FadE12; Medium chain acyl-CoA dehydrogenase; MCADH; EC 1.3.99.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
29% identity, 74% coverage of query (116 bits)
masA / CAO03071.1 MasA protein from Azoarcus sp. HxN1 (see paper)
28% identity, 98% coverage of query (115 bits)
PS417_17015 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) from Pseudomonas simiae WCS417
27% identity, 97% coverage of query (114 bits)
B5UB85 isovaleryl-CoA dehydrogenase (EC 1.3.8.4) from Bombyx mori (see paper)
27% identity, 97% coverage of query (114 bits)
hlmB / E2PZ80 L-cysteinyl-[NRPS] dehydrogenase from Streptomyces clavuligerus (see paper)
31% identity, 96% coverage of query (112 bits)
ACADS / P16219 short-chain acyl-CoA dehydrogenase monomer (EC 1.3.8.1) from Homo sapiens (see 11 papers)
ACADS_HUMAN / P16219 Short-chain specific acyl-CoA dehydrogenase, mitochondrial; SCAD; Butyryl-CoA dehydrogenase; EC 1.3.8.1 from Homo sapiens (Human) (see 4 papers)
26% identity, 97% coverage of query (111 bits)
7y0aC / P16219 Crystal structure of human short-chain acyl-coa dehydrogenase
26% identity, 97% coverage of query (111 bits)
7y0bA Crystal structure of human short-chain acyl-coa dehydrogenase
26% identity, 97% coverage of query (111 bits)
acdA / J7TF92 cinnamate reductase monomer (EC 1.3.8.15) from Clostridium sporogenes (strain ATCC 15579) (see 6 papers)
ACDA_CLOS1 / J7TF92 3-(aryl)acrylate reductase; EC 1.3.8.15 from Clostridium sporogenes (strain ATCC 15579) (see paper)
J7TF92 3-(aryl)acrylate reductase (EC 1.3.8.15) from Clostridium sporogenes (see paper)
25% identity, 96% coverage of query (110 bits)
D4QEZ8 short-chain acyl-CoA dehydrogenase (EC 1.3.8.1) from Homo sapiens (see paper)
26% identity, 97% coverage of query (110 bits)
8sgsA Short-chain specific acyl-CoA dehydrogenase, mitochondrial
26% identity, 96% coverage of query (110 bits)
2pg0A / Q5L0D5 Crystal structure of acyl-coa dehydrogenase from geobacillus kaustophilus
27% identity, 97% coverage of query (109 bits)
ACADL / P28330 long-chain-acyl-CoA dehydrogenase monomer (EC 1.3.8.8; EC 1.3.8.7) from Homo sapiens (see 8 papers)
ACADL_HUMAN / P28330 Long-chain specific acyl-CoA dehydrogenase, mitochondrial; LCAD; EC 1.3.8.8 from Homo sapiens (Human) (see 3 papers)
26% identity, 95% coverage of query (108 bits)
Sama_1362 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) from Shewanella amazonensis SB2B
26% identity, 97% coverage of query (108 bits)
ACADS_RAT / P15651 Short-chain specific acyl-CoA dehydrogenase, mitochondrial; SCAD; Butyryl-CoA dehydrogenase; EC 1.3.8.1 from Rattus norvegicus (Rat) (see 2 papers)
P15651 short-chain acyl-CoA dehydrogenase (EC 1.3.8.1) from Rattus norvegicus (see 2 papers)
25% identity, 97% coverage of query (107 bits)
1jqiA Crystal structure of rat short chain acyl-coa dehydrogenase complexed with acetoacetyl-coa
25% identity, 97% coverage of query (107 bits)
ivd2 / CAC08234.1 isovaleryl-CoA dehydrogenase, partial from Solanum tuberosum (see paper)
27% identity, 99% coverage of query (106 bits)
2vigB Crystal structure of human short-chain acyl coa dehydrogenase
25% identity, 96% coverage of query (106 bits)
ptmO4 / D8L2U8 (4S)-homoplatensicyl-CoA dehydrogenase from Streptomyces platensis (see paper)
D8L2U8 long-chain acyl-CoA dehydrogenase (EC 1.3.8.8) from Streptomyces platensis (see paper)
28% identity, 86% coverage of query (105 bits)
ACADS_BOVIN / Q3ZBF6 Short-chain specific acyl-CoA dehydrogenase, mitochondrial; SCAD; Butyryl-CoA dehydrogenase; EC 1.3.8.1 from Bos taurus (Bovine) (see paper)
26% identity, 97% coverage of query (104 bits)
4l1fA / D2RL84 Electron transferring flavoprotein of acidaminococcus fermentans: towards a mechanism of flavin-based electron bifurcation (see paper)
25% identity, 90% coverage of query (101 bits)
Q18AQ1 butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin) (subunit 3/3) (EC 1.3.1.109); short-chain acyl-CoA dehydrogenase (EC 1.3.8.1) from Clostridioides difficile (see paper)
5ol2F / A0A125V4E7 The electron transferring flavoprotein/butyryl-coa dehydrogenase complex from clostridium difficile (see paper)
25% identity, 95% coverage of query (100 bits)
4iv6B / A0QTW7 X-ray crystal structure of an isovaleryl-coa dehydrogenase from mycobacterium smegmatis (see paper)
27% identity, 98% coverage of query (96.7 bits)
2z1qB / Q5SJW0 Crystal structure of acyl coa dehydrogenase
26% identity, 86% coverage of query (93.2 bits)
6af6A / Q5W271 Piga with fad and proline (see paper)
28% identity, 88% coverage of query (92.4 bits)
8pheA / Q9H845 Acad9-wt in complex with ecsit-cter (see paper)
26% identity, 85% coverage of query (87.8 bits)
ACAD9_HUMAN / Q9H845 Complex I assembly factor ACAD9, mitochondrial; Acyl-CoA dehydrogenase family member 9; ACAD-9; EC 1.3.8.- from Homo sapiens (Human) (see 14 papers)
26% identity, 85% coverage of query (87.4 bits)
8phfA Cryo-em structure of human acad9-s191a
26% identity, 85% coverage of query (86.7 bits)
1egcA Structure of t255e, e376g mutant of human medium chain acyl-coa dehydrogenase complexed with octanoyl-coa
25% identity, 84% coverage of query (85.1 bits)
ACDS_MEGEL / Q06319 Acyl-CoA dehydrogenase, short-chain specific; Butyryl-CoA dehydrogenase; BCAD; SCAD; EC 1.3.8.1 from Megasphaera elsdenii (see paper)
1bucA / Q06319 Three-dimensional structure of butyryl-coa dehydrogenase from megasphaera elsdenii (see paper)
GI|149886 butyryl-CoA dehydrogenase; EC 1.3.99.2 from Megasphaera elsdenii (see 2 papers)
27% identity, 82% coverage of query (84.0 bits)
2a1tC / P11310 Structure of the human mcad:etf e165betaa complex (see paper)
24% identity, 84% coverage of query (82.8 bits)
CARC_ACEWD / H6LGM6 Caffeyl-CoA reductase-Etf complex subunit CarC; Caffeoyl-CoA reductase CarC; NADH-dependent caffeyl-CoA reduction; EC 1.3.1.108 from Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) (see paper)
H6LGM6 caffeoyl-CoA reductase (subunit 3/3) (EC 1.3.1.108) from Acetobacterium woodii (see paper)
6fahD / H6LGM6 Molecular basis of the flavin-based electron-bifurcating caffeyl-coa reductase reaction (see paper)
25% identity, 95% coverage of query (82.8 bits)
ACADM / P11310 mitochondrial medium-chain acyl-CoA dehydrogenase monomer (EC 1.3.8.7) from Homo sapiens (see 16 papers)
ACADM_HUMAN / P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD; Medium chain acyl-CoA dehydrogenase; MCADH; EC 1.3.8.7 from Homo sapiens (Human) (see 25 papers)
P11310 medium-chain acyl-CoA dehydrogenase (EC 1.3.8.7) from Homo sapiens (see 3 papers)
24% identity, 84% coverage of query (82.4 bits)
3mdeA Crystal structures of medium chain acyl-coa dehydrogenase from pig liver mitochondria with and without substrate
25% identity, 84% coverage of query (81.6 bits)
3mddA / P41367 Crystal structures of medium chain acyl-coa dehydrogenase from pig liver mitochondria with and without substrate (see paper)
25% identity, 84% coverage of query (81.6 bits)
1udyA Medium-chain acyl-coa dehydrogenase with 3-thiaoctanoyl-coa
25% identity, 84% coverage of query (81.6 bits)
ACADM_PIG / P41367 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; MCAD; EC 1.3.8.7 from Sus scrofa (Pig) (see 3 papers)
P41367 medium-chain acyl-CoA dehydrogenase (EC 1.3.8.7) from Sus scrofa (see paper)
24% identity, 84% coverage of query (81.3 bits)
ACADM_DROME / Q9VSA3 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial; EC 1.3.8.7 from Drosophila melanogaster (Fruit fly) (see paper)
24% identity, 85% coverage of query (79.3 bits)
1ukwB Crystal structure of medium-chain acyl-coa dehydrogenase from thermus thermophilus hb8
26% identity, 86% coverage of query (79.3 bits)
1ukwA / Q72JJ3 Crystal structure of medium-chain acyl-coa dehydrogenase from thermus thermophilus hb8
26% identity, 86% coverage of query (79.3 bits)
3p4tA Crystal structure of a putative acyl-coa dehydrogenase from mycobacterium smegmatis
25% identity, 97% coverage of query (77.4 bits)
3oibA / A0R3J1 Crystal structure of a putative acyl-coa dehydrogenase from mycobacterium smegmatis, iodide soak (see paper)
25% identity, 97% coverage of query (77.4 bits)
3owaC / A0A6H3ADM7 Crystal structure of acyl-coa dehydrogenase complexed with fad from bacillus anthracis
25% identity, 77% coverage of query (77.0 bits)
8ciwA / A0A1H5ILA2 Methylsuccinyl-coa dehydrogenase from pseudomonas migulae with bound fad and (2s)-methylsuccinyl-coa (see paper)
27% identity, 78% coverage of query (75.1 bits)
4hr3A / B1MFF5 Structure of a putative acyl-coa dehydrogenase from mycobacterium abscessus (see paper)
29% identity, 72% coverage of query (73.9 bits)
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