Sites on a Tree

 

Searching for up to 100 curated homologs for GFF53 PS417_00270 alcohol dehydrogenase (420 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

gadh2 / Q4KKM6 D-gluconate dehydrogenase cytochrome c subunit (EC 1.1.99.3) from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
    84% identity, 99% coverage of query (723 bits)

A0A2H4PJM7 gluconate 2-dehydrogenase (subunit 1/3) (EC 1.1.1.215) from Pseudomonas plecoglossicida (see paper)
    75% identity, 99% coverage of query (667 bits)

gadh2 / O34215 gluconate 2-dehydrogenase cytochrome c subunit (EC 1.1.99.3) from Pantoea cypripedii (see paper)
GADH2_PANCY / O34215 Gluconate 2-dehydrogenase cytochrome c subunit; GA 2-DH cytochrome c subunit; GADH cytochrome c subunit; EC 1.1.99.3 from Pantoea cypripedii (Pectobacterium cypripedii) (Erwinia cypripedii) (see paper)
    66% identity, 98% coverage of query (559 bits)

ADHB_GLUPO / P0A388 Alcohol dehydrogenase (quinone), cytochrome c subunit; ADH; Alcohol dehydrogenase (quinone), subunit II; Cytochrome c-553; Cytochrome c553; Ethanol:Q2 reductase; G3-ADH subunit II; Quinohemoprotein-cytochrome c complex; Ubiquinol oxidase; EC 1.1.5.5 from Gluconacetobacter polyoxogenes (Acetobacter polyoxogenes) (see paper)
    55% identity, 97% coverage of query (471 bits)

adhB / Q47945 alcohol dehydrogenase cytochrome c subunit (EC 1.1.5.5) from Gluconobacter oxydans (strain 621H) (see 2 papers)
ADHB_GLUOX / Q47945 Alcohol dehydrogenase (quinone), cytochrome c subunit; ADH; Alcohol dehydrogenase (quinone), subunit II; Cytochrome c-553; Cytochrome c553; Ethanol:Q2 reductase; G3-ADH subunit II; Quinohemoprotein-cytochrome c complex; Ubiquinol oxidase; EC 1.1.5.5 from Gluconobacter oxydans (strain 621H) (Gluconobacter suboxydans) (see 5 papers)
    55% identity, 96% coverage of query (462 bits)

8gy2B / Q47945 Cryo-em structure of membrane-bound alcohol dehydrogenase from gluconobacter oxydans
    56% identity, 94% coverage of query (461 bits)

Q5FRK5 gluconate 2-dehydrogenase (EC 1.1.1.215) from Gluconobacter oxydans (see paper)
    52% identity, 98% coverage of query (453 bits)

C7G3B8 alcohol dehydrogenase (cytochrome c) (EC 1.1.2.8) from Acetobacter pasteurianus (see paper)
    54% identity, 99% coverage of query (447 bits)

D2SZY5 alcohol dehydrogenase (cytochrome c) (EC 1.1.2.8) from Acetobacter pasteurianus (see paper)
    54% identity, 99% coverage of query (447 bits)

C9K502 alcohol dehydrogenase (cytochrome c) (EC 1.1.2.8) from Acetobacter pasteurianus (see paper)
    54% identity, 99% coverage of query (445 bits)

PP_3623 vanillin dehydrogenase, cytochrome c component from Pseudomonas putida KT2440
    52% identity, 96% coverage of query (404 bits)

PS417_10880 cytochrome c component of deoxyribose dehydrogenase from Pseudomonas simiae WCS417
    52% identity, 94% coverage of query (399 bits)

fdhC / M1V1V5 fructose dehydrogenase cytochrome subunit (EC 1.1.5.14) from Gluconobacter japonicus (see 4 papers)
FDHC_GLUJA / M1V1V5 Fructose dehydrogenase cytochrome subunit; Fructose dehydrogenase subunit II from Gluconobacter japonicus (see 2 papers)
fdhC / BAM93251.1 cytochrome subunit of fructose dehydrogenase from Gluconobacter japonicus (see 2 papers)
    36% identity, 98% coverage of query (255 bits)

8jejC Cryo-em structure of na-dithionite reduced membrane-bound fructose dehydrogenase from gluconobacter japonicus
    37% identity, 93% coverage of query (255 bits)

7w2jC / M1V1V5 Cryo-em structure of membrane-bound fructose dehydrogenase from gluconobacter japonicus
    38% identity, 93% coverage of query (253 bits)

A0A0B6VQJ4 dehydrogluconate dehydrogenase (subunit 3/3) (EC 1.1.99.4) from Gluconobacter oxydans (see paper)
    37% identity, 96% coverage of query (247 bits)

B1PHD3 nicotinate dehydrogenase (EC 1.17.1.5) from Comamonas testosteroni (see paper)
    39% identity, 93% coverage of query (245 bits)

nicB / Q88FX8 nicotinate hydroxylase large subunit (EC 1.17.2.1) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
NICB_PSEPK / Q88FX8 Nicotinate dehydrogenase subunit B; Nicotinate degradation protein B; Nicotinate dehydrogenase large subunit; EC 1.17.2.1 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
Q88FX8 nicotinate dehydrogenase (EC 1.17.1.5); nicotinate dehydrogenase (cytochrome) (EC 1.17.2.1) from Pseudomonas putida (see paper)
    39% identity, 88% coverage of query (235 bits)

aldF / CAA69953.1 cytochrome c from Komagataeibacter europaeus (see paper)
    34% identity, 87% coverage of query (191 bits)

8gy3A / Q5DW50 Cryo-em structure of membrane-bound aldehyde dehydrogenase from gluconobacter oxydans
    34% identity, 90% coverage of query (190 bits)

Build an alignment

Build an alignment for GFF53 and 20 homologs with ≥ 30% identity

Select sequences

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory