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Searching for up to 100 curated homologs for GFF586 FitnessBrowser__Phaeo:GFF586 (101 a.a.)

Found high-coverage hits (≥70%) to 6 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

2h9dD / Q51507 Pyruvate-bound structure of the isochorismate-pyruvate lyase from pseudomonas aerugionsa (see paper)
    33% identity, 93% coverage of query (51.2 bits)

pchB / Q51507 isochorismate pyruvate lyase (EC 4.2.99.21) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
PCHB_PSEAE / Q51507 Isochorismate pyruvate lyase; IPL; Chorismate mutase; CM; Salicylate biosynthesis protein; EC 4.2.99.21; EC 5.4.99.5 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 6 papers)
Q51507 isochorismate lyase (EC 4.2.99.21) from Pseudomonas aeruginosa (see 3 papers)
    33% identity, 93% coverage of query (51.2 bits)

TyrA / b2600 fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
tyrA / P07023 fused chorismate mutase/prephenate dehydrogenase (EC 5.4.99.5; EC 1.3.1.12) from Escherichia coli (strain K12) (see 12 papers)
    33% identity, 84% coverage of query (50.1 bits)

2h9cA Native crystal structure of the isochorismate-pyruvate lyase from pseudomonas aeruginosa
    31% identity, 93% coverage of query (47.8 bits)

P43902 prephenate dehydrogenase (EC 1.3.1.12) from Haemophilus influenzae (see paper)
    33% identity, 78% coverage of query (44.3 bits)

Build an alignment

Build an alignment for GFF586 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

2h9dA / Q51507 Pyruvate-bound structure of the isochorismate-pyruvate lyase from pseudomonas aerugionsa (see paper)
    29% identity, 89% coverage of query (43.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory