Searching for up to 100 curated homologs for GFF67 FitnessBrowser__Marino:GFF67 (133 a.a.)
Found high-coverage hits (≥70%) to 47 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YdgB / b1606 dihydromonapterin reductase (EC 1.5.1.50; EC 1.5.1.3) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
folM / P0AFS3 dihydromonapterin reductase (EC 1.5.1.50; EC 1.5.1.3) from Escherichia coli (strain K12) (see 6 papers)
FOLM_ECOLI / P0AFS3 Dihydromonapterin reductase; H(2)-MPt reductase; Dihydrofolate reductase; DHFR; EC 1.5.1.50; EC 1.5.1.3 from Escherichia coli (strain K12) (see 2 papers)
P0AFS3 dihydromonapterin reductase (EC 1.5.1.50) from Escherichia coli (see 3 papers)
folM / RF|NP_416123 dihydrofolate reductase folM; EC 1.5.1.3 from Escherichia coli K12 (see 4 papers)
52% identity, 100% coverage of query (145 bits)
Build an alignment for GFF67 and 1 homologs with ≥ 30% identity
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5bt9C / A9MA73 Crystal structure of folm alternative dihydrofolate reductase 1 from brucella canis complexed with NADP (see paper)
29% identity, 99% coverage of query (67.8 bits)
pruA / Q7CZX3 dihydropterin reductase monomer (EC 1.5.1.33; EC 1.5.1.50) from Agrobacterium fabrum (strain C58 / ATCC 33970) (see 2 papers)
29% identity, 99% coverage of query (67.8 bits)
swb2 / D2KTX1 3-hydroxykynurenate reductase/dehydratase from Streptomyces sp. SNA15896 (see paper)
28% identity, 98% coverage of query (59.7 bits)
gra-orf6 / BAD51477.1 ketoreductase from Streptomyces violaceoruber (see 3 papers)
31% identity, 83% coverage of query (57.0 bits)
FABG_AQUAE / O67610 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Aquifex aeolicus (strain VF5)
39% identity, 77% coverage of query (55.8 bits)
4jroC / Q8Y690 Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (fabg) from listeria monocytogenes in complex with NADP+
29% identity, 95% coverage of query (54.7 bits)
4nbtA / A9NFJ2 Crystal structure of fabg from acholeplasma laidlawii (see paper)
31% identity, 83% coverage of query (51.6 bits)
S5U393 7alpha-hydroxysteroid dehydrogenase (EC 1.1.1.159) from Comamonas testosteroni (see paper)
30% identity, 77% coverage of query (50.8 bits)
3gegA / A3DFK9 Fingerprint and structural analysis of a scor enzyme with its bound cofactor from clostridium thermocellum (see paper)
27% identity, 98% coverage of query (50.1 bits)
FABG_RICPR / P50941 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Rickettsia prowazekii (strain Madrid E)
P50941 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Rickettsia prowazekii (see paper)
29% identity, 95% coverage of query (49.7 bits)
DCXR_MOUSE / Q91X52 L-xylulose reductase; XR; Dicarbonyl/L-xylulose reductase; EC 1.1.1.10 from Mus musculus (Mouse) (see paper)
Q91X52 L-xylulose reductase (EC 1.1.1.10) from Mus musculus (see paper)
29% identity, 80% coverage of query (49.3 bits)
FABG_SYNY3 / P73574 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-acyl carrier protein reductase; EC 1.1.1.100 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
26% identity, 95% coverage of query (48.9 bits)
DER_CHICK / Q8JIS3 D-erythrulose reductase; Probable L-xylulose reductase; XR; EC 1.1.1.162; EC 1.1.1.10 from Gallus gallus (Chicken) (see 2 papers)
27% identity, 80% coverage of query (48.5 bits)
Q31QF3 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Synechococcus elongatus PCC 7942 = FACHB-805 (see paper)
27% identity, 95% coverage of query (48.5 bits)
DCXR_RAT / Q920P0 L-xylulose reductase; XR; Dicarbonyl/L-xylulose reductase; EC 1.1.1.10 from Rattus norvegicus (Rat) (see 3 papers)
Q920P0 L-xylulose reductase (EC 1.1.1.10) from Rattus norvegicus (see paper)
29% identity, 80% coverage of query (48.5 bits)
fabG / D4YGY5 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see paper)
26% identity, 98% coverage of query (47.8 bits)
NR_NARAP / A0A1C9II22 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- from Narcissus aff. pseudonarcissus MK-2014 (Daffodil) (see paper)
NR_NARPS / A0A1A9TAK5 Noroxomaritidine/norcraugsodine reductase; NorRed; EC 1.1.1.- from Narcissus pseudonarcissus (Daffodil) (see 2 papers)
5ff9B / A0A1A9TAK5 Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and tyramine (see paper)
25% identity, 100% coverage of query (47.8 bits)
5fffA Noroxomaritidine/norcraugsodine reductase in complex with NADP+ and piperonal
25% identity, 100% coverage of query (47.8 bits)
DCXR / Q91XV4 L-xylulose reductase subunit (EC 1.1.1.10) from Mesocricetus auratus (see paper)
DCXR_MESAU / Q91XV4 L-xylulose reductase; XR; Dicarbonyl/L-xylulose reductase; Sperm antigen P26h; EC 1.1.1.10 from Mesocricetus auratus (Golden hamster) (see 3 papers)
Q91XV4 L-xylulose reductase (EC 1.1.1.10) from Mesocricetus auratus (see paper)
27% identity, 84% coverage of query (47.4 bits)
DCXR_CAVPO / Q920N9 L-xylulose reductase; XR; Dicarbonyl/L-xylulose reductase; Protein P26h; EC 1.1.1.10 from Cavia porcellus (Guinea pig) (see paper)
Q920N9 L-xylulose reductase (EC 1.1.1.10) from Cavia porcellus (see paper)
29% identity, 80% coverage of query (47.4 bits)
DCXR_HUMAN / Q7Z4W1 L-xylulose reductase; XR; Carbonyl reductase II; Dicarbonyl/L-xylulose reductase; Kidney dicarbonyl reductase; kiDCR; Short chain dehydrogenase/reductase family 20C member 1; Sperm surface protein P34H; EC 1.1.1.10 from Homo sapiens (Human) (see 5 papers)
Q7Z4W1 L-xylulose reductase (EC 1.1.1.10) from Homo sapiens (see 3 papers)
3d3wA / Q7Z4W1 Structure of l-xylulose reductase with bound coenzyme, phosphate and hydroxide. (see paper)
28% identity, 80% coverage of query (46.6 bits)
1pr9A Human l-xylulose reductase holoenzyme
28% identity, 80% coverage of query (46.6 bits)
BBSD_THAAR / Q9KJF1 (2S)-[(R)-hydroxy(phenyl)methyl]succinyl-CoA dehydrogenase subunit BbsD; (S,R)-2-(alpha-hydroxybenzyl)succinyl-CoA dehydrogenase subunit BbsD; EC 1.1.1.429 from Thauera aromatica (see 2 papers)
27% identity, 98% coverage of query (46.2 bits)
7pcsB / Q9KJF1 Structure of the heterotetrameric sdr family member bbscd (see paper)
27% identity, 98% coverage of query (46.2 bits)
3op4A Crystal structure of putative 3-ketoacyl-(acyl-carrier-protein) reductase from vibrio cholerae o1 biovar eltor str. N16961 in complex with NADP+ (see paper)
30% identity, 80% coverage of query (46.2 bits)
2d1yA Crystal structure of tt0321 from thermus thermophilus hb8
28% identity, 95% coverage of query (45.8 bits)
4i08A Crystal structure of beta-ketoacyl-acyl carrier protein reductase (fabg) from vibrio cholerae in complex with NADPH
30% identity, 80% coverage of query (45.8 bits)
A0A5P1R8U8 acetoacetyl-CoA reductase (subunit 2/2) (EC 1.1.1.36) from Neptunomonas concharum (see paper)
26% identity, 84% coverage of query (45.4 bits)
SO1683 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) from Shewanella oneidensis MR-1
25% identity, 98% coverage of query (45.4 bits)
7xqmB / Q72LQ6 Indel-mutant short chain dehydrogenase bound to sah (see paper)
28% identity, 95% coverage of query (45.1 bits)
Q2FZ53 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Staphylococcus aureus (see paper)
29% identity, 80% coverage of query (44.7 bits)
FABG_STAAM / P0A0H9 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Staphylococcus aureus (strain Mu50 / ATCC 700699)
3osuA / P0A0H9 Crystal structure of the 3-oxoacyl-acyl carrier protein reductase, fabg, from staphylococcus aureus
29% identity, 80% coverage of query (44.7 bits)
fabG / P51831 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Bacillus subtilis (strain 168) (see 3 papers)
31% identity, 77% coverage of query (43.9 bits)
CBR4 / Q8N4T8 carbonyl reductase family member 4 (EC 1.1.1.100) from Homo sapiens (see 2 papers)
CBR4_HUMAN / Q8N4T8 3-oxoacyl-[acyl-carrier-protein] reductase; 3-ketoacyl-[acyl-carrier-protein] reductase beta subunit; KAR beta subunit; Carbonyl reductase family member 4; CBR4; Quinone reductase CBR4; Short chain dehydrogenase/reductase family 45C member 1; EC 1.1.1.100; EC 1.6.5.10 from Homo sapiens (Human) (see 3 papers)
29% identity, 81% coverage of query (43.9 bits)
4cqmF / Q8N4T8 Crystal structure of heterotetrameric human ketoacyl reductase complexed with NAD and NADP (see paper)
29% identity, 81% coverage of query (43.9 bits)
Q4UN54 acetoacetyl-CoA reductase (EC 1.1.1.36) from Rickettsia felis (see paper)
30% identity, 80% coverage of query (43.5 bits)
FabG / b1093 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
fabG / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG (EC 1.1.1.100) from Escherichia coli (strain K12) (see 22 papers)
FABG_ECOLI / P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase FabG; 3-ketoacyl-acyl carrier protein reductase; Beta-Ketoacyl-acyl carrier protein reductase; Beta-ketoacyl-ACP reductase; EC 1.1.1.100 from Escherichia coli (strain K12) (see 9 papers)
P0AEK2 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) from Escherichia coli (see 2 papers)
28% identity, 80% coverage of query (43.5 bits)
1q7bA The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
28% identity, 80% coverage of query (43.5 bits)
5t5qC / Q2YL80 Crystal structure of short-chain dehydrogenase/reductase sdr:glucose/ribitol dehydrogenase from brucella melitensis
25% identity, 93% coverage of query (43.1 bits)
3sj7A Structure of beta-ketoacetyl-coa reductase (fabg) from staphylococcus aureus complex with NADPH
28% identity, 80% coverage of query (42.4 bits)
PHAB_SYNY3 / P73826 Acetoacetyl-CoA reductase; EC 1.1.1.36 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
28% identity, 85% coverage of query (42.4 bits)
1q7cA The structure of betaketoacyl-[acp] reductase y151f mutant in complex with NADPH fragment
27% identity, 80% coverage of query (42.4 bits)
5mlnB / B8K244 The crystal structure of alcohol dehydrogenase 10 from candida magnoliae
25% identity, 98% coverage of query (42.0 bits)
4k6fB / B4EAU4 X-ray crystal structure of a putative acetoacetyl-coa reductase from burkholderia cenocepacia bound to the co-factor NADP
29% identity, 92% coverage of query (41.6 bits)
4qecA / I6ZQW6 Elxo with NADP bound (see paper)
29% identity, 77% coverage of query (41.2 bits)
4nbuB Crystal structure of fabg from bacillus sp (see paper)
28% identity, 82% coverage of query (40.4 bits)
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Lawrence Berkeley National Laboratory