Searching for up to 100 curated homologs for GFF875 FitnessBrowser__psRCH2:GFF875 (379 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YYCR_BACSU / Q45604 Uncharacterized zinc-type alcohol dehydrogenase-like protein YycR; EC 1.-.-.- from Bacillus subtilis (strain 168) (see paper)
42% identity, 96% coverage of query (280 bits)
4jlwA Crystal structure of formaldehyde dehydrogenase from pseudomonas aeruginosa (see paper)
44% identity, 96% coverage of query (278 bits)
Q9HTE3 formaldehyde dehydrogenase (EC 1.2.1.46) from Pseudomonas aeruginosa (see paper)
44% identity, 96% coverage of query (278 bits)
FADH_PSEPU / P46154 Glutathione-independent formaldehyde dehydrogenase; FALDH; FDH; Formaldehyde dismutase; EC 1.2.1.46; EC 1.2.98.1 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
P46154 formaldehyde dehydrogenase (EC 1.2.1.46) from Pseudomonas putida (see paper)
42% identity, 96% coverage of query (260 bits)
1kolA / P46154 Crystal structure of formaldehyde dehydrogenase (see paper)
42% identity, 96% coverage of query (258 bits)
A0A224AQI3 formaldehyde dismutase (EC 1.2.98.1) from Methylobacterium sp. FD1 (see 2 papers)
36% identity, 99% coverage of query (240 bits)
2dphA / Q52078 Crystal structure of formaldehyde dismutase
39% identity, 96% coverage of query (231 bits)
FDM_PSEPU / Q52078 Formaldehyde dismutase; EC 1.2.98.1 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 2 papers)
39% identity, 96% coverage of query (231 bits)
A0A6F8QRG1 formaldehyde dismutase (EC 1.2.98.1) from Methylobacterium sp. FD1 (see paper)
36% identity, 96% coverage of query (226 bits)
YbdR / b0608 putative Zn2+-dependent alcohol dehydrogenase YbdR from Escherichia coli K-12 substr. MG1655 (see paper)
35% identity, 100% coverage of query (220 bits)
B2ZRE3 alcohol dehydrogenase (EC 1.1.1.1) from Thermus sp. (see paper)
34% identity, 99% coverage of query (210 bits)
4cpdA / B2ZRE3 Alcohol dehydrogenase tadh from thermus sp. Atn1
34% identity, 99% coverage of query (210 bits)
ADHB_BACSU / O06012 Uncharacterized zinc-type alcohol dehydrogenase-like protein AdhB; EC 1.-.-.- from Bacillus subtilis (strain 168) (see paper)
35% identity, 99% coverage of query (207 bits)
YHG1_SCHPO / Q9P6I8 Zinc-type alcohol dehydrogenase-like protein C1198.01; EC 1.-.-.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
31% identity, 98% coverage of query (185 bits)
D4GP73 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Haloferax volcanii (see paper)
35% identity, 99% coverage of query (182 bits)
adh2 / Q768S7 NAD+-dependent secondary alcohol dehydrogenase II monomer from Gordonia sp. (strain TY-5) (see paper)
33% identity, 99% coverage of query (176 bits)
Q9HMB6 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Halobacterium sp. (see paper)
33% identity, 99% coverage of query (176 bits)
Q5V676 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Haloarcula marismortui (see paper)
34% identity, 99% coverage of query (164 bits)
5ylnA / A0A0H2ZRI0 Zinc dependent alcohol dehydrogenase 2 from streptococcus pneumonia - apo form
32% identity, 99% coverage of query (161 bits)
Q5M4K4 alcohol dehydrogenase (EC 1.1.1.1) from Streptococcus thermophilus (see paper)
30% identity, 99% coverage of query (151 bits)
Build an alignment for GFF875 and 20 homologs with ≥ 30% identity
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ADH_CUPNH / Q0KDL6 Alcohol dehydrogenase; EC 1.1.1.1; EC 1.1.1.4; EC 1.2.1.3 from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see 2 papers)
28% identity, 99% coverage of query (134 bits)
gutB / Q06004 glucitol dehydrogenase monomer (EC 1.1.1.9; EC 1.1.1.14) from Bacillus subtilis (strain 168) (see paper)
DHSO_BACSU / Q06004 Sorbitol dehydrogenase; SDH; Glucitol dehydrogenase; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Bacillus subtilis (strain 168) (see paper)
gutB / GI|304153 L-iditol 2-dehydrogenase; EC 1.1.1.14 from Bacillus subtilis subsp. subtilis str. 168 (see 3 papers)
gutB / AAA22508.1 sorbitol dehydrogenase from Bacillus subtilis (see paper)
34% identity, 75% coverage of query (134 bits)
xdhA / Q5GN51 D-xylulose reductase (EC 1.1.1.9) from Aspergillus niger (see paper)
30% identity, 85% coverage of query (127 bits)
7y9pA / P22144 Xylitol dehydrogenase s96c/s99c/y102c mutant(thermostabilized form) from pichia stipitis (see paper)
30% identity, 94% coverage of query (121 bits)
A2DJ40 isopropanol dehydrogenase (NADP+) (EC 1.1.1.80) from Trichomonas vaginalis (see paper)
30% identity, 87% coverage of query (116 bits)
TDH_PYRFU / Q8U259 L-threonine 3-dehydrogenase; TDH; L-threonine dehydrogenase; EC 1.1.1.103 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see paper)
Q8U259 alcohol dehydrogenase (EC 1.1.1.1) from Pyrococcus furiosus (see paper)
30% identity, 93% coverage of query (116 bits)
xdhA / Q86ZV0 NAD+-dependent xylitol dehydrogenase (EC 1.1.1.9) from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (see paper)
XYL2_ASPOR / Q86ZV0 D-xylulose reductase A; Xylitol dehydrogenase A; EC 1.1.1.9 from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) (see paper)
Q86ZV0 D-xylulose reductase (EC 1.1.1.9) from Aspergillus oryzae (see 3 papers)
GI|83774265 xylitol dehydrogenase; EC 1.1.1.9 from Aspergillus oryzae (see paper)
xdhA / BAC75870.2 xylitol dehydrogenase from Aspergillus oryzae (see paper)
29% identity, 85% coverage of query (115 bits)
TDH_PYRHO / O58389 L-threonine 3-dehydrogenase; L-ThrDH; TDH; L-threonine dehydrogenase; EC 1.1.1.103 from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) (see 3 papers)
O58389 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Pyrococcus horikoshii (see 2 papers)
30% identity, 93% coverage of query (115 bits)
2dfvA / O58389 Hyperthermophilic threonine dehydrogenase from pyrococcus horikoshii (see paper)
30% identity, 93% coverage of query (114 bits)
DHSO1_YEAST / P35497 Sorbitol dehydrogenase 1; SDH 1; Polyol dehydrogenase; Xylitol dehydrogenase; EC 1.1.1.-; EC 1.1.1.9 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P35497 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Saccharomyces cerevisiae (see 2 papers)
27% identity, 95% coverage of query (114 bits)
Q07786 L-iditol 2-dehydrogenase (EC 1.1.1.14) from Saccharomyces cerevisiae (see 2 papers)
27% identity, 95% coverage of query (114 bits)
GulDH / E1V4Y1 L-gulonate 5-dehydrogenase (EC 1.1.1.380) from Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9) (see paper)
E1V4Y1 L-gulonate 5-dehydrogenase (EC 1.1.1.380) from Halomonas elongata (see paper)
30% identity, 99% coverage of query (110 bits)
B0KBL1 alcohol dehydrogenase (EC 1.1.1.1) from Thermoanaerobacter pseudethanolicus (see paper)
28% identity, 93% coverage of query (110 bits)
7ux4A Crystallographic snapshots of ternary complexes of thermophilic secondary alcohol dehydrogenase from thermoanaerobacter pseudoethanolicus reveal the dynamics of ligand exchange and the proton relay network.
28% identity, 93% coverage of query (110 bits)
7uutA Ternary complex crystal structure of secondary alcohol dehydrogenases from the thermoanaerobacter ethanolicus mutants c295a and i86a provides better understanding of catalytic mechanism
28% identity, 93% coverage of query (110 bits)
ADH_THEBR / P14941 NADP-dependent isopropanol dehydrogenase; EC 1.1.1.80 from Thermoanaerobacter brockii (Thermoanaerobium brockii) (see 2 papers)
P14941 isopropanol dehydrogenase (NADP+) (EC 1.1.1.80) from Thermoanaerobacter brockii (see 2 papers)
28% identity, 93% coverage of query (109 bits)
5kiaA / Q2T9E1 Crystal structure of l-threonine 3-dehydrogenase from burkholderia thailandensis
29% identity, 88% coverage of query (109 bits)
xdh1 / Q876R2 D-sorbitol dehydrogenase (EC 1.1.1.14; EC 1.1.1.9) from Hypocrea jecorina (see paper)
31% identity, 85% coverage of query (109 bits)
1ykfA NADP-dependent alcohol dehydrogenase from thermoanaerobium brockii
28% identity, 93% coverage of query (109 bits)
1bxzB Crystal structure of a thermophilic alcohol dehydrogenase substrate complex from thermoanaerobacter brockii
28% identity, 93% coverage of query (109 bits)
G3AIB3 D-xylulose reductase (EC 1.1.1.9) from Spathaspora passalidarum (see paper)
27% identity, 94% coverage of query (108 bits)
F8S123 alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Thermococcus guaymasensis (see paper)
29% identity, 93% coverage of query (108 bits)
Tdh / b3616 threonine dehydrogenase (EC 1.1.1.103) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
tdh / P07913 threonine dehydrogenase (EC 1.1.1.103) from Escherichia coli (strain K12) (see 10 papers)
TDH_ECOLI / P07913 L-threonine 3-dehydrogenase; TDH; L-threonine dehydrogenase; EC 1.1.1.103 from Escherichia coli (strain K12) (see 2 papers)
P07913 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Escherichia coli (see paper)
30% identity, 92% coverage of query (108 bits)
sdhA / A2QM95 L-arabinitol dehydrogenase (EC 1.1.1.12; EC 1.1.1.9; EC 1.1.1.14) from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) (see 3 papers)
30% identity, 98% coverage of query (106 bits)
7f3pD / P14941 Crystal structure of a NADP-dependent alcohol dehydrogenase mutant in apo form (see paper)
28% identity, 93% coverage of query (106 bits)
G3AIP8 D-xylulose reductase (EC 1.1.1.9) from Spathaspora passalidarum (see paper)
26% identity, 94% coverage of query (103 bits)
O31776 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Bacillus subtilis (see paper)
30% identity, 99% coverage of query (103 bits)
3gfbA / Q5JI69 L-threonine dehydrogenase (tktdh) from the hyperthermophilic archaeon thermococcus kodakaraensis (see paper)
28% identity, 93% coverage of query (102 bits)
TDH_THEKO / Q5JI69 L-threonine 3-dehydrogenase; TDH; L-threonine dehydrogenase; EC 1.1.1.103 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see 2 papers)
Q5JI69 L-threonine 3-dehydrogenase (EC 1.1.1.103) from Thermococcus kodakarensis (see 2 papers)
28% identity, 93% coverage of query (101 bits)
TDH_THET8 / Q5SKS4 L-threonine 3-dehydrogenase; TDH; EC 1.1.1.103 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
2dq4A / Q5SKS4 Crystal structure of threonine 3-dehydrogenase
29% identity, 94% coverage of query (100 bits)
2ejvA Crystal structure of threonine 3-dehydrogenase complexed with NAD+
29% identity, 94% coverage of query (100 bits)
E7EKB8 (R,R)-butanediol dehydrogenase (EC 1.1.1.4) from Paenibacillus polymyxa (see paper)
25% identity, 100% coverage of query (99.8 bits)
1vj0A / Q9WYR7 Crystal structure of alcohol dehydrogenase (tm0436) from thermotoga maritima at 2.00 a resolution
27% identity, 98% coverage of query (97.8 bits)
4ej6A / Q92PZ3 Crystal structure of a putative zinc-binding dehydrogenase (target psi-012003) from sinorhizobium meliloti 1021
27% identity, 100% coverage of query (97.1 bits)
4ejmA Crystal structure of a putative zinc-binding dehydrogenase (target psi-012003) from sinorhizobium meliloti 1021 bound to NADP
27% identity, 99% coverage of query (96.7 bits)
DHSO_SHEEP / P07846 Sorbitol dehydrogenase; SDH; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Ovis aries (Sheep) (see 3 papers)
26% identity, 99% coverage of query (93.6 bits)
DHSO_HUMAN / Q00796 Sorbitol dehydrogenase; SDH; (R,R)-butanediol dehydrogenase; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Ribitol dehydrogenase; RDH; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.4; EC 1.1.1.14; EC 1.1.1.56; EC 1.1.1.9 from Homo sapiens (Human) (see 8 papers)
25% identity, 95% coverage of query (92.0 bits)
5o9dA Crystal structure of r. Ruber adh-a, mutant y294f, w295a, y54f, f43h, h39y
27% identity, 96% coverage of query (92.0 bits)
6ffxA Crystal structure of r. Ruber adh-a, mutant f43h (see paper)
26% identity, 96% coverage of query (91.7 bits)
1pl6A / Q00796 Human sdh/nadh/inhibitor complex (see paper)
25% identity, 95% coverage of query (91.7 bits)
3qe3A / P07846 Sheep liver sorbitol dehydrogenase (see paper)
25% identity, 99% coverage of query (89.4 bits)
5tnxA / B1Z4S6 Crystal structure of alcohol dehydrogenase zinc-binding domain protein from burkholderia ambifaria
29% identity, 86% coverage of query (88.6 bits)
DHSO_RAT / P27867 Sorbitol dehydrogenase; SDH; L-iditol 2-dehydrogenase; Polyol dehydrogenase; Xylitol dehydrogenase; XDH; EC 1.1.1.-; EC 1.1.1.14; EC 1.1.1.9 from Rattus norvegicus (Rat) (see 5 papers)
27% identity, 99% coverage of query (88.2 bits)
1e3jA / O96496 Ketose reductase (sorbitol dehydrogenase) from silverleaf whitefly (see paper)
26% identity, 99% coverage of query (87.8 bits)
LAD_PENRW / B6HI95 L-arabinitol 4-dehydrogenase; LAD; EC 1.1.1.12 from Penicillium rubens (strain ATCC 28089 / DSM 1075 / NRRL 1951 / Wisconsin 54-1255) (Penicillium chrysogenum) (see paper)
B6HI95 L-arabinitol 4-dehydrogenase (EC 1.1.1.12) from Penicillium chrysogenum (see paper)
25% identity, 92% coverage of query (84.3 bits)
ladA / A2QAC0 L-arabinitol 4-dehydrogenase (EC 1.1.1.9; EC 1.1.1.12) from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) (see 2 papers)
LAD_ASPNC / A2QAC0 L-arabinitol 4-dehydrogenase; LAD; EC 1.1.1.12 from Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513) (see 3 papers)
A2QAC0 L-arabinitol 4-dehydrogenase (EC 1.1.1.12) from Aspergillus niger (see 2 papers)
25% identity, 95% coverage of query (79.3 bits)
P80468 All-trans-retinol dehydrogenase [NAD(+)] ADH4; Alcohol dehydrogenase 4; Alcohol dehydrogenase class II; EC 1.1.1.105 from Struthio camelus (Common ostrich)
25% identity, 98% coverage of query (78.2 bits)
P49645 Alcohol dehydrogenase 1; Alcohol dehydrogenase I; EC 1.1.1.1 from Apteryx australis (Southern brown kiwi)
27% identity, 97% coverage of query (76.6 bits)
3m6iA / Q7SI09 L-arabinitol 4-dehydrogenase (see paper)
24% identity, 96% coverage of query (75.5 bits)
LAD_NEUCR / Q7SI09 L-arabinitol 4-dehydrogenase; LAD; EC 1.1.1.12 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) (see 2 papers)
Q7SI09 L-arabinitol 4-dehydrogenase (EC 1.1.1.12) from Neurospora crassa (see paper)
23% identity, 96% coverage of query (75.1 bits)
7cyiD / A0A2U1Q018 Crystal structure of alcohol dehydrogenase 1 from artemisia annua
27% identity, 71% coverage of query (73.9 bits)
lad1 / Q96V44 D-galactitol dehydrogenase (EC 1.1.1.12) from Hypocrea jecorina (see paper)
LAD_HYPJE / Q96V44 L-arabinitol 4-dehydrogenase; LAD; EC 1.1.1.12 from Hypocrea jecorina (Trichoderma reesei) (see 4 papers)
Q96V44 L-arabinitol 4-dehydrogenase (EC 1.1.1.12) from Trichoderma reesei (see 5 papers)
22% identity, 93% coverage of query (72.8 bits)
1p0fA Crystal structure of the binary complex: NADP(h)-dependent vertebrate alcohol dehydrogenase (adh8) with the cofactor NADP
24% identity, 76% coverage of query (70.1 bits)
1p0cA / O57380 Crystal structure of the NADP(h)-dependent vertebrate alcohol dehydrogenase (adh8) (see paper)
24% identity, 76% coverage of query (70.1 bits)
2cd9A / O93715 Sulfolobus solfataricus glucose dehydrogenase 1 - apo form (see paper)
25% identity, 98% coverage of query (70.1 bits)
1n8kA Horse liver alcohol dehydrogenase val292thr mutant complexed to NAD+ and pyrazole
23% identity, 76% coverage of query (69.7 bits)
ADH1E_HORSE / P00327 Alcohol dehydrogenase E chain; EC 1.1.1.1 from Equus caballus (Horse) (see paper)
23% identity, 76% coverage of query (69.7 bits)
8eiwA Cobalt(ii)-substituted horse liver alcohol dehydrogenase in complex with nadh and n-cyclohexylformamide
23% identity, 76% coverage of query (69.7 bits)
7k35A Eqadh-nadh-4-methylbenzyl alcohol, p21
23% identity, 76% coverage of query (69.7 bits)
7adhA Three-dimensional structure of isonicotinimidylated liver alcohol dehydrogenase
23% identity, 76% coverage of query (69.7 bits)
6xt2A Eqadh-nadh-heptafluorobutanol, p21
23% identity, 76% coverage of query (69.7 bits)
5vn1A Horse liver alcohol dehydrogenae complexed with nadh (r,s)-n-1- methylhexylformamide
23% identity, 76% coverage of query (69.7 bits)
5vl0A Horse liver alcohol dehydrogenase complexed with nadh and n- benzyformamide
23% identity, 76% coverage of query (69.7 bits)
5vjgA Horse liver alcohol dehydrogenase complexed with 2,2'bipyridine
23% identity, 76% coverage of query (69.7 bits)
5vj5A Horse liver alcohol dehydrogenase complexed with 1,10-phenanthroline
23% identity, 76% coverage of query (69.7 bits)
5adhA Interdomain motion in liver alcohol dehydrogenase. Structural and energetic analysis of the hinge bending mode
23% identity, 76% coverage of query (69.7 bits)
2oxiA Refined crystal structure of cu-substituted alcohol dehydrogenase at 2.1 angstroms resolution
23% identity, 76% coverage of query (69.7 bits)
2jhgA Structural evidence for a ligand coordination switch in liver alcohol dehydrogenase
23% identity, 76% coverage of query (69.7 bits)
2jhfA Structural evidence for a ligand coordination switch in liver alcohol dehydrogenase
23% identity, 76% coverage of query (69.7 bits)
1p1rA Horse liver alcohol dehydrogenase complexed with nadh and r-n-1- methylhexylformamide
23% identity, 76% coverage of query (69.7 bits)
1n92A Horse liver alcohol dehydrogenase complexed with NAD+ and 4- iodopyrazole
23% identity, 76% coverage of query (69.7 bits)
1mg0A Horse liver alcohol dehydrogenase complexed with NAD+ and 2,3- difluorobenzyl alcohol
23% identity, 76% coverage of query (69.7 bits)
1ldyA Horse liver alcohol dehydrogenase complexed to nadh and cyclohexyl formamide (cxf)
23% identity, 76% coverage of query (69.7 bits)
1ldeA Horse liver alcohol dehydrogenase complexed to nadh and n-formyl piperdine
23% identity, 76% coverage of query (69.7 bits)
1hldA Structures of horse liver alcohol dehydrogenase complexed with NAD+ and substituted benzyl alcohols
23% identity, 76% coverage of query (69.7 bits)
1btoA Horse liver alcohol dehydrogenase complexed to nadh and (1s,3r)3- butylthiolane 1-oxide
23% identity, 76% coverage of query (69.7 bits)
1adgA Crystallographic studies of two alcohol dehydrogenase-bound analogs of thiazole-4-carboxamide adenine dinucleotide (tad), the active anabolite of the antitumor agent tiazofurin
23% identity, 76% coverage of query (69.7 bits)
1adfA Crystallographic studies of two alcohol dehydrogenase-bound analogs of thiazole-4-carboxamide adenine dinucleotide (tad), the active anabolite of the antitumor agent tiazofurin
23% identity, 76% coverage of query (69.7 bits)
1adbA Crystallographic studies of isosteric NAD analogues bound to alcohol dehydrogenase: specificity and substrate binding in two ternary complexes
23% identity, 76% coverage of query (69.7 bits)
1qv6A Horse liver alcohol dehydrogenase his51gln/lys228arg mutant complexed with NAD+ and 2,4-difluorobenzyl alcohol
23% identity, 76% coverage of query (68.2 bits)
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