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Searching for up to 100 curated homologs for GFF981 FitnessBrowser__Phaeo:GFF981 (397 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PfGW456L13_4288 Kynureninase (EC 3.7.1.3) from Pseudomonas fluorescens GW456-L13
    49% identity, 98% coverage of query (404 bits)

AO353_05935 Kynureninase (EC 3.7.1.3) from Pseudomonas fluorescens FW300-N2E3
    49% identity, 98% coverage of query (402 bits)

PS417_23650 Kynureninase (EC 3.7.1.3) from Pseudomonas simiae WCS417
    49% identity, 98% coverage of query (400 bits)

kyn / P83788 kynureninase subunit (EC 3.7.1.3) from Pseudomonas fluorescens (see 2 papers)
KYNU_PSEFL / P83788 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Pseudomonas fluorescens (see paper)
    49% identity, 98% coverage of query (397 bits)

1qz9A / P83788 The three dimensional structure of kynureninase from pseudomonas fluorescens (see paper)
    49% identity, 95% coverage of query (387 bits)

BPHYT_RS16030 Kynureninase (EC 3.7.1.3) from Burkholderia phytofirmans PsJN
    48% identity, 99% coverage of query (380 bits)

RR42_RS15385 Kynureninase (EC 3.7.1.3) from Cupriavidus basilensis FW507-4G11
    51% identity, 97% coverage of query (380 bits)

sibQ / C0LTN1 kynureninase (EC 3.7.1.3) from Streptosporangium sibiricum (see paper)
    41% identity, 93% coverage of query (269 bits)

acmH / D6R244 3-hydroxy-4-methyl-D-kynurenine hydrolase monomer from Streptomyces anulatus (see 4 papers)
    39% identity, 93% coverage of query (236 bits)

B7XB98 kynureninase (EC 3.7.1.3) from Bombyx mori (see paper)
    30% identity, 94% coverage of query (207 bits)

KYNU_MOUSE / Q9CXF0 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Mus musculus (Mouse) (see paper)
    31% identity, 92% coverage of query (178 bits)

Build an alignment

Build an alignment for GFF981 and 11 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

Kynu / P70712 kynureninase subunit (EC 3.7.1.3) from Rattus norvegicus (see paper)
KYNU_RAT / P70712 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Rattus norvegicus (Rat) (see paper)
    29% identity, 94% coverage of query (176 bits)

acmK / D6R233 3-hydroxy-4-methyl-D-kynurenine hydrolase monomer from Streptomyces anulatus (see 4 papers)
    38% identity, 70% coverage of query (166 bits)

KYNU_CAEEL / Q18026 Kynureninase; Abnormal fluorescence under UV illumination; L-kynurenine hydrolase; EC 3.7.1.3 from Caenorhabditis elegans (see paper)
    28% identity, 91% coverage of query (165 bits)

KYNU / Q16719 Kynureninase (EC 3.7.1.3) from Homo sapiens (see 5 papers)
KYNU_HUMAN / Q16719 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Homo sapiens (Human) (see 6 papers)
Q16719 kynureninase (EC 3.7.1.3) from Homo sapiens (see 4 papers)
    29% identity, 95% coverage of query (164 bits)

3e9kA Crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex
    29% identity, 92% coverage of query (164 bits)

2hzpA / Q16719 Crystal structure of homo sapiens kynureninase (see paper)
    29% identity, 92% coverage of query (160 bits)

KYNU_YEAST / Q05979 Kynureninase; Biosynthesis of nicotinic acid protein 5; L-kynurenine hydrolase; EC 3.7.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
    27% identity, 92% coverage of query (141 bits)

cefD / P18549 isopenicillin N epimerase (EC 5.1.1.17) from Streptomyces clavuligerus (see 3 papers)
    26% identity, 88% coverage of query (81.6 bits)

Q6B7Z5 L-cysteine desulfidase (EC 4.4.1.28) from Pseudomonas sp. (see paper)
    26% identity, 81% coverage of query (57.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory