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Searching for up to 100 curated homologs for GFF991 FitnessBrowser__WCS417:GFF991 (213 a.a.)

Found high-coverage hits (≥70%) to 87 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO356_16835 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2C3
    81% identity, 99% coverage of query (352 bits)

Pf6N2E2_5292 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E2
    80% identity, 99% coverage of query (351 bits)

AO353_15560 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E3
    77% identity, 99% coverage of query (347 bits)

SO1671 Maleylacetoacetate isomerase (EC 5.2.1.2) from Shewanella oneidensis MR-1
    46% identity, 98% coverage of query (171 bits)

2v6kA / O86043 Structure of maleyl pyruvate isomerase, a bacterial glutathione-s- transferase in zeta class, in complex with substrate analogue dicarboxyethyl glutathione (see paper)
    46% identity, 99% coverage of query (169 bits)

nagL / O86043 glutathion-dependent maleylpyruvate isomerase (EC 5.2.1.4) from Ralstonia sp. (see paper)
NAGL_RALSP / O86043 Maleylpyruvate isomerase; MPI; Naphthalene degradation protein L; EC 5.2.1.4 from Ralstonia sp. (see 2 papers)
    46% identity, 99% coverage of query (169 bits)

2jl4A Holo structure of maleyl pyruvate isomerase, a bacterial glutathione- s-transferase in zeta class
    46% identity, 99% coverage of query (169 bits)

Q5K5T6 glutathione transferase subunit (EC 2.5.1.18) from Escherichia coli (see 8 papers)
    42% identity, 100% coverage of query (164 bits)

Psest_3511 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas stutzeri RCH2
    46% identity, 99% coverage of query (161 bits)

MAAI2_DROME / Q9VHD2 Probable maleylacetoacetate isomerase 2; MAAI 2; Glutathione S-transferase zeta 2; EC 5.2.1.2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    42% identity, 98% coverage of query (159 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    41% identity, 99% coverage of query (155 bits)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
    41% identity, 99% coverage of query (155 bits)

1fw1A / O43708 Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
    42% identity, 99% coverage of query (154 bits)

GSTZ1 / O43708 maleylacetoacetate isomerase/glutathione transferase ζ monomer (EC 2.5.1.18; EC 5.2.1.2) from Homo sapiens (see 11 papers)
MAAI_HUMAN / O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
O43708 glutathione transferase (EC 2.5.1.18); maleylacetoacetate isomerase (EC 5.2.1.2) from Homo sapiens (see 8 papers)
    42% identity, 99% coverage of query (151 bits)

MAAI_RAT / P57113 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Rattus norvegicus (Rat) (see paper)
    41% identity, 99% coverage of query (151 bits)

MAAI1_DROME / Q9VHD3 Probable maleylacetoacetate isomerase 1; MAAI 1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    38% identity, 98% coverage of query (146 bits)

Ac3H11_2306 Maleylacetoacetate isomerase (EC 5.2.1.2) from Acidovorax sp. GW101-3H11
    40% identity, 100% coverage of query (144 bits)

GSTZ1_ARATH / Q9ZVQ3 Glutathione S-transferase Z1; AtGSTZ1; GST class-zeta member 1; Glutathione S-transferase 18; Maleylacetone isomerase; MAI; EC 2.5.1.18; EC 5.2.1.- from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    39% identity, 100% coverage of query (140 bits)

4kdyA / B8J605 Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans 2cp-1, target efi-507175, with bound gsh in the active site
    40% identity, 99% coverage of query (133 bits)

4kaeA Crystal structure of maleylacetoacetate isomerase from anaeromyxobacter dehalogenans 2cp-1, target efi-507175, with bound dicarboxyethyl glutathione and citrate in the active site
    40% identity, 99% coverage of query (133 bits)

O04437 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    36% identity, 99% coverage of query (123 bits)

maiA / O43123 maleylacetoacetate isomerase (EC 5.2.1.2) from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (see paper)
MAAI_EMENI / O43123 Maleylacetoacetate isomerase; MAAI; EC 5.2.1.2 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
O43123 maleylacetoacetate isomerase (EC 5.2.1.2) from Aspergillus nidulans (see paper)
GI|2832725 maleylacetoacetate isomerase; EC 5.2.1.2 from Emericella nidulans (see paper)
maiA / CAA05041.1 maleylacetoacetate isomerase from Aspergillus nidulans (see paper)
maiA / CAA05044.1 maleylacetoacetate isomerase from Aspergillus nidulans (see paper)
    37% identity, 99% coverage of query (122 bits)

4pxoA / C5ATQ9 Crystal structure of maleylacetoacetate isomerase from methylobacteriu extorquens am1 with bound malonate and gsh (target efi-507068)
    36% identity, 100% coverage of query (121 bits)

MAIA_ASPFU / Q4WHT7 Maleylacetoacetate isomerase maiA; EC 5.2.1.2 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 3 papers)
    37% identity, 99% coverage of query (119 bits)

3n5oA / D2YW48 Crystal structure of putative glutathione transferase from coccidioides immitis bound to glutathione (see paper)
    36% identity, 99% coverage of query (118 bits)

D2YW48 Probable glutathione S-transferase; EC 2.5.1.18 from Coccidioides immitis (strain RS) (Valley fever fungus)
    36% identity, 99% coverage of query (118 bits)

6m1tA / O30347 Bacterial beta class sphingomonas chungbukensis glutathione s- transferase
    30% identity, 85% coverage of query (69.7 bits)

Build an alignment

Build an alignment for GFF991 and 27 homologs with ≥ 30% identity

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Change minimum %identity:

Additional hits (identity < 30%)

3qawA / B9VX79 Crystal structure of a glutathione-s-transferase from antarctic clam laternula elliptica in a complex with glutathione (see paper)
    25% identity, 98% coverage of query (65.9 bits)

GSTF3_MAIZE / P04907 Glutathione S-transferase 3; GST class-phi member 3; GST-III; EC 2.5.1.18 from Zea mays (Maize) (see 2 papers)
    31% identity, 90% coverage of query (63.9 bits)

4gf0A / A3STM0 Crystal structure of glutahtione transferase homolog from sulfitobacter, target efi-501084, with bound glutathione
    28% identity, 70% coverage of query (63.5 bits)

1f2eA / O33705 Structure of sphingomonad, glutathione s-transferase complexed with glutathione
GST / AAC46031.1 glutathione S-transferase from Sphingomonas paucimobilis (see paper)
    29% identity, 85% coverage of query (61.2 bits)

4g9hA / Q8D0L3 Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target efi-501894, with bound glutathione
    25% identity, 93% coverage of query (61.2 bits)

D2WL48 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    26% identity, 78% coverage of query (59.7 bits)

Q59721 4-chlorobenzoate dehalogenase (EC 3.8.1.6) from Burkholderia sp. (see paper)
bphK / CAA54033.1 glutathione S-transferase from Paraburkholderia xenovorans LB400 (see paper)
    27% identity, 93% coverage of query (59.7 bits)

2gdrA / Q59721 Crystal structure of a bacterial glutathione transferase (see paper)
    27% identity, 93% coverage of query (58.9 bits)

GSTD7_DROME / Q9VG93 Glutathione S-transferase D7; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    24% identity, 88% coverage of query (58.9 bits)

2dsaA Ternary complex of bphk, a bacterial gst
    27% identity, 93% coverage of query (58.9 bits)

GSTF8 / Q96266 glutathione S-transferase F8 monomer (EC 2.5.1.18) from Arabidopsis thaliana (see 6 papers)
GSTF8_ARATH / Q96266 Glutathione S-transferase F8, chloroplastic; AtGSTF8; AtGSTF5; GST class-phi member 8; Glutathione S-transferase 6; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    29% identity, 91% coverage of query (58.2 bits)

GSTF1_TOBAC / P30109 Glutathione S-transferase PARB; GST class-phi; EC 2.5.1.18 from Nicotiana tabacum (Common tobacco) (see paper)
    29% identity, 91% coverage of query (58.2 bits)

GSTF2_TOBAC / P46440 Glutathione S-transferase APIC; GST class-phi; EC 2.5.1.18 from Nicotiana tabacum (Common tobacco)
    27% identity, 91% coverage of query (56.6 bits)

D2WL57 glutathione transferase (EC 2.5.1.18) from Populus trichocarpa (see paper)
    30% identity, 77% coverage of query (56.2 bits)

A0A4Y5R0C1 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    31% identity, 73% coverage of query (55.8 bits)

4hojA / O33374 Crystal structure of glutathione transferase homolog from neisseria gonorrhoeae, target efi-501841, with bound glutathione
    27% identity, 95% coverage of query (55.5 bits)

3uarA / Q60CN1 Crystal structure of glutathione transferase (target efi-501774) from methylococcus capsulatus str. Bath with gsh bound
    28% identity, 87% coverage of query (55.1 bits)

4qq7A / B4E6Q3 Crystal structure of putative stringent starvation protein a from burkholderia cenocepacia with bound glutathione
    26% identity, 95% coverage of query (55.1 bits)

5f8bA / Q4WB03 Crystallographic structure of psoe with co (see paper)
    27% identity, 74% coverage of query (53.9 bits)

XYLK / AAC44159.1 glutathione S-transferase from Cycloclasticus oligotrophus (see paper)
    26% identity, 95% coverage of query (53.9 bits)

A0A4Y5R0K8 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    29% identity, 77% coverage of query (53.5 bits)

PSOE_ASPFU / Q4WB03 Glutathione S-transferase psoE; Pseurotin biosynthesis protein E; EC 2.5.1.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 4 papers)
    27% identity, 74% coverage of query (53.5 bits)

A0A4Y5QZX0 glutathione transferase (EC 2.5.1.18) from Salix babylonica (see paper)
    27% identity, 78% coverage of query (53.5 bits)

4hz2B / A7ILT8 Crystal structure of glutathione s-transferase xaut_3756 (target efi- 507152) from xanthobacter autotrophicus py2
    28% identity, 90% coverage of query (53.1 bits)

GST_PROMI / P15214 Glutathione S-transferase GST-6.0; GST B1-1; EC 2.5.1.18 from Proteus mirabilis (see paper)
    24% identity, 92% coverage of query (53.1 bits)

1pmtA / P15214 Glutathione transferase from proteus mirabilis (see paper)
    24% identity, 92% coverage of query (53.1 bits)

4ri6A / A9PHH6 Crystal structure of poplar glutathione transferase f1 (see paper)
    27% identity, 76% coverage of query (52.8 bits)

4gltA / Q1GZF4 Crystal structure of glutathione s-transferase mfla_2116 (target efi- 507160) from methylobacillus flagellatus kt with gsh bound
    28% identity, 74% coverage of query (52.4 bits)

Pog / b3229 stringent starvation protein A from Escherichia coli K-12 substr. MG1655 (see 8 papers)
TC 1.A.12.3.1 / P0ACA3 The bacterial CLIC homologue, stringent starvation protein A, SspA (212 aas; 0 TMSs) [N-terminal Trx domain; C-terminal glutathione S-transferase (GST) domain] from Escherichia coli (strain K12) (see 5 papers)
sspA stringent starvation protein A from Escherichia coli K12 (see 5 papers)
    28% identity, 80% coverage of query (51.2 bits)

3wd6A / A8R5V3 Crystal structure of bombyx mori omega-class glutathione transferase in complex with gsh (see paper)
    27% identity, 73% coverage of query (51.2 bits)

4yavA Crystal structure of ligg in complex with b-glutathionyl- acetoveratrone (gs-av) from sphingobium sp. Strain syk-6
    27% identity, 88% coverage of query (51.2 bits)

4g10A / Q9WXJ9 Ligg from sphingobium sp. Syk-6 is related to the glutathione transferase omega class (see paper)
    27% identity, 88% coverage of query (50.8 bits)

4kh7B / Q8Z859 Crystal structure of a glutathione transferase family member from salmonella enterica ty2, target efi-507262, with bound glutathione
    24% identity, 92% coverage of query (50.8 bits)

6gicB Crystal structure of glutathione transferase omega 2s from trametes versicolor in complex with oxyresveratrol
    29% identity, 74% coverage of query (50.4 bits)

6gibB / A0A452CSY5 Crystal structure of glutathione transferase omega 2s from trametes versicolor
    29% identity, 74% coverage of query (50.4 bits)

7dweA / A0A4Y5R087 Crystal structure of a glutathione s-transferase sbgstu7 from salix babylonica in complex with glutathione
    28% identity, 77% coverage of query (50.4 bits)

4chsA Crystal structure of a tau class glutathione transferase 10 from glycine max
    27% identity, 78% coverage of query (49.3 bits)

7rhpA / A0A7M7GUY7 Crystal structure of honeybee (apis mellifera) glutathione s- transferase amgstd1 (see paper)
    27% identity, 74% coverage of query (48.9 bits)

7zvpA Crystal structure of poplar glutathione transferase u19 in complex with glutathione
    28% identity, 77% coverage of query (48.5 bits)

5agyA / I1MJ34 Crystal structure of a tau class gst mutant from glycine (see paper)
    26% identity, 93% coverage of query (48.1 bits)

3touA / Q8XVV6 Crystal structure of glutathione transferase (target efi-501058) from ralstonia solanacearum gmi1000 with gsh bound
    25% identity, 96% coverage of query (47.4 bits)

4mk3A / Q1LJ46 Crystal structure of a glutathione transferase family member from cupriavidus metallidurans ch34, target efi-507362, with bound glutathione sulfinic acid (gso2h)
    25% identity, 77% coverage of query (47.0 bits)

4topA Glycine max glutathione transferase
    25% identity, 93% coverage of query (46.6 bits)

4e8hB / O61996 Structural of bombyx mori glutathione transferase bmgstd1 complex with gtt
    24% identity, 77% coverage of query (46.2 bits)

3g7iB Crystal structure of a delta class gst (adgstd4-4) from anopheles dirus, with glutathione complexed in one subunit
    26% identity, 88% coverage of query (46.2 bits)

5j4uA / B9I0G5 Crystal structure of a glutathione s-transferase ptgstu30 from populus trichocarpa in complex with gsh
    26% identity, 78% coverage of query (45.1 bits)

6ht6A Crystal structure of glutathione transferase omega 2s from trametes versicolor in complex with 2,4-dihydroxybenzophenone
    27% identity, 74% coverage of query (44.7 bits)

6gicA Crystal structure of glutathione transferase omega 2s from trametes versicolor in complex with oxyresveratrol
    27% identity, 74% coverage of query (44.7 bits)

1jzrA / P23202 Ure2p in complex with glutathione (see paper)
    23% identity, 94% coverage of query (43.5 bits)

3pr8A / Q88RE7 Structure of glutathione s-transferase(pp0183) from pseudomonas putida in complex with gsh
    28% identity, 73% coverage of query (43.5 bits)

8a0pA / D2X9R3 Crystal structure of poplar glutathione transferase u20 in complex with morin (see paper)
    27% identity, 77% coverage of query (43.1 bits)

8a0rA Crystal structure of poplar glutathione transferase u20 in complex with pinocembrin
    27% identity, 77% coverage of query (43.1 bits)

8a0qA Crystal structure of poplar glutathione transferase u20 in complex with baicalein
    27% identity, 77% coverage of query (43.1 bits)

8a0oA Crystal structure of poplar glutathione transferase u20 in complex with galangin
    27% identity, 77% coverage of query (43.1 bits)

8a0iA Crystal structure of poplar glutathione transferase u20 in complex with glutathionylphenylacetophenone
    27% identity, 77% coverage of query (43.1 bits)

8a08A Crystal structure of poplar glutathione transferase u20 in complex with glutathione
    27% identity, 77% coverage of query (43.1 bits)

1k0aA Ure2p in complex with s-hexylglutathione
    21% identity, 94% coverage of query (43.1 bits)

4ivfF / A5E437 Crystal structure of glutathione transferase homolog from lodderomyces elongisporus, target efi-501753, with two gsh per subunit
    20% identity, 84% coverage of query (42.7 bits)

1a0fA Crystal structure of glutathione s-transferase from escherichia coli complexed with glutathionesulfonic acid
    27% identity, 92% coverage of query (42.4 bits)

Gst / b1635 glutathione S-transferase GstA (EC 2.5.1.18) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
gstA / P0A9D2 glutathione S-transferase GstA (EC 2.5.1.18) from Escherichia coli (strain K12) (see 8 papers)
GSTA_ECOLI / P0A9D2 Glutathione S-transferase GstA; GST B1-1; EC 2.5.1.18 from Escherichia coli (strain K12) (see 6 papers)
GST / BAA07509.1 glutathione transferase from Escherichia coli (see paper)
    27% identity, 92% coverage of query (42.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory