Searching for up to 100 curated homologs for GFF992 FitnessBrowser__WCS417:GFF992 (455 a.a.)
Found high-coverage hits (≥70%) to 54 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PCAK_ACIAD / Q43975 4-hydroxybenzoate transporter PcaK; 4-HB transporter from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
37% identity, 90% coverage of query (294 bits)
PCAK_PSEPU / Q51955 4-hydroxybenzoate transporter PcaK from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
TC 2.A.1.15.1 / Q51955 4-Hydroxybenzoate/protocatechuate porter from Pseudomonas putida (see paper)
pcaK / AAA85137.1 PcaK from Pseudomonas putida (see paper)
37% identity, 92% coverage of query (276 bits)
GALT_PSEPU / E8ZB61 Gallate transporter; Gallate permease from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
galT / CBJ94499.1 gallic acid permease from Pseudomonas putida (see paper)
41% identity, 86% coverage of query (261 bits)
MHBT_KLEOX / Q5EXK5 3-hydroxybenzoate transporter MhbT from Klebsiella oxytoca (see paper)
36% identity, 98% coverage of query (257 bits)
proT / BAB32694.1 putative transporter from Pseudomonas straminea (see 2 papers)
32% identity, 96% coverage of query (239 bits)
TC 2.A.1.15.5 / O30513 Benzoate porter, BenK from Acinetobacter calcoaceticus (see 2 papers)
31% identity, 96% coverage of query (225 bits)
TC 2.A.1.15.7 / Q6FBB3 Aromatic compound (benzoate) uptake transporter of 450 aas from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
33% identity, 92% coverage of query (219 bits)
TC 2.A.1.15.14 / Q8VUZ0 Probable uptake transporter for 2,4-dichlorophenoxyacetic acid (2,4-D), CadK from Bradyrhizobium sp. HW13
34% identity, 87% coverage of query (208 bits)
TC 2.A.1.15.3 / Q46M63 2,4-Dichlorophenoxyacetate porter (see 5 papers)
32% identity, 98% coverage of query (207 bits)
TC 2.A.1.15.6 / O24842 Vanillate porter, VanK (see 4 papers)
30% identity, 95% coverage of query (201 bits)
Build an alignment for GFF992 and 10 homologs with ≥ 30% identity
Or download the sequences
NIAP_ACIAD / Q6FFF7 Niacin transporter NiaP from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
28% identity, 95% coverage of query (184 bits)
TC 2.A.1.15.11 / Q6M372 The Vanillate porter, VanK from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
30% identity, 96% coverage of query (152 bits)
YaiK / b0353 3-hydroxyphenylpropionate/3-hydroxycinnamate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpT / P77589 3-hydroxyphenylpropionate/3-hydroxycinnamate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
MHPT_ECOLI / P77589 3-(3-hydroxy-phenyl)propionate transporter; 3HPP transporter; 3-(3-hydroxy-phenyl)propionate:H(+) symporter; 3HPP:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.15.2 / P77589 MhpT. A specific 3-(3-hydroxyphenyl)propionate (3HPP) transporter; vital for E. coli K-12 W3110 to grow on this substrate from Escherichia coli (see 3 papers)
34% identity, 83% coverage of query (152 bits)
TC 2.A.1.15.8 / O24723 Probable 1-hydroxy-2-naphthoate transporter, orf1 (see paper)
26% identity, 96% coverage of query (142 bits)
genK / Q8NLB7 gentisate transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
GENK_CORGL / Q8NLB7 Gentisate transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
30% identity, 85% coverage of query (139 bits)
NIAP_BACSU / O34691 Putative niacin/nicotinamide transporter NiaP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.82.4 / O34691 Niacin uptake porter NiaP from Bacillus subtilis (see 2 papers)
28% identity, 89% coverage of query (131 bits)
TC 2.A.1.15.9 / O51798 Probable 4-methylmuconolactone transporter, MmlH from Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) (see paper)
28% identity, 79% coverage of query (99.0 bits)
TC 2.A.1.15.4 / P94131 cis,cis-muconate porter, MucK from Acinetobacter calcoaceticus (see 2 papers)
mucK / AAC27117.1 cis,cis-muconate transport protein MucK from Acinetobacter baylyi (see paper)
26% identity, 80% coverage of query (95.1 bits)
S22AD_HUMAN / Q9Y226 Solute carrier family 22 member 13; Organic anion transporter 10; OAT10; Organic cation transporter-like 3; ORCTL-3; ORCTL3 from Homo sapiens (Human) (see 5 papers)
TC 2.A.1.19.17 / Q9Y226 Kidney organic cation transporter-like 3 ORCTL-3 (OAT10; SLC22A13; Like-3) (Bahn et al., 2008) (transports nicotinate, p-aminohippurate and urate; KM=20-40 mμM) via exchange for lactate) from Homo sapiens (Human) (see 4 papers)
26% identity, 88% coverage of query (90.9 bits)
SVOP_BOVIN / Q1JP63 Synaptic vesicle 2-related protein; SV2-related protein from Bos taurus (Bovine) (see paper)
24% identity, 93% coverage of query (85.5 bits)
YdjE / b1769 putative transporter YdjE from Escherichia coli K-12 substr. MG1655 (see 3 papers)
TC 2.A.1.1.92 / P38055 Inner membrane metabolite transport protein YdjE from Escherichia coli (strain K12) (see 6 papers)
25% identity, 96% coverage of query (83.2 bits)
YgcS / b2771 putative transporter YgcS from Escherichia coli K-12 substr. MG1655 (see 2 papers)
TC 2.A.1.1.95 / Q46909 Inner membrane metabolite transport protein YgcS from Escherichia coli (strain K12) (see 3 papers)
27% identity, 84% coverage of query (82.0 bits)
SVOP_XENLA / Q2XWK0 Synaptic vesicle 2-related protein; SV2-related protein from Xenopus laevis (African clawed frog) (see paper)
23% identity, 93% coverage of query (81.3 bits)
SAUU_CUPNH / Q0K843 Probable sulfoacetate transporter SauU from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
27% identity, 73% coverage of query (80.5 bits)
YaaU / b0045 putative transporter YaaU from Escherichia coli K-12 substr. MG1655 (see 4 papers)
24% identity, 80% coverage of query (79.7 bits)
TC 2.A.1.82.1 / F2CRE4 The barley copper uptake porter, CT-1 of 749 aas; nearly identical to the wheat orthologue from Hordeum vulgare var. distichum
22% identity, 90% coverage of query (76.6 bits)
S22AD_MOUSE / Q6A4L0 Solute carrier family 22 member 13; Organic anion transporter 10; OAT10; Organic cation transporter-like 3; ORCTL-3 from Mus musculus (Mouse) (see paper)
26% identity, 78% coverage of query (76.3 bits)
NanX / b4279 sialic acid transporter NanX from Escherichia coli K-12 substr. MG1655 (see 5 papers)
nanX / P39352 sialic acid transporter NanX from Escherichia coli (strain K12) (see 4 papers)
YJHB_ECOLI / P39352 Putative metabolite transport protein YjhB from Escherichia coli (strain K12) (see paper)
22% identity, 82% coverage of query (76.3 bits)
SVOP_RAT / Q9Z2I7 Synaptic vesicle 2-related protein; SV2-related protein from Rattus norvegicus (Rat) (see paper)
23% identity, 97% coverage of query (74.3 bits)
TC 2.A.1.82.3 / Q8BFT9 Synaptic vesicle 2-related protein (SV2-related protein), SVOP from Mus musculus (see 4 papers)
23% identity, 97% coverage of query (73.2 bits)
BWI76_RS23725 2-deoxy-D-ribonate transporter 2 from Klebsiella michiganensis M5al
22% identity, 71% coverage of query (70.9 bits)
S22AB_HUMAN / Q9NSA0 Solute carrier family 22 member 11; Organic anion transporter 4; OAT4; Organic anion:dicarboxylate exchanger OAT4 from Homo sapiens (Human) (see 11 papers)
TC 2.A.1.19.10 / Q9NSA0 The apical proximal tubular kidney/placenta organic anion transporter 4, Oat4 (Slc22a11) (transports estrone sulfate (Km = 1 µM), dehydroepiandrosterone sulfate (Km = 60µM), many anionic drugs, diuretics, bile salts, urate and ochratoxin A). Catalyzes Na+-independent efflux, possibly using glutamate as a counter anion in an exchange reaction, especially in the placenta from Homo sapiens (Human) (see 7 papers)
SLC22A11 / GB|BAA95316.1 solute carrier family 22 member 11 from Homo sapiens
25% identity, 73% coverage of query (70.5 bits)
GUDP_BACSU / P42237 Probable galactarate/D-glucarate transporter GudP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.14.1 / P42237 Glucarate porter from Bacillus subtilis (see 3 papers)
22% identity, 77% coverage of query (69.3 bits)
YdjK / b1775 putative transporter YdjK from Escherichia coli K-12 substr. MG1655 (see 3 papers)
22% identity, 88% coverage of query (65.9 bits)
8bw7A Cryo-em structure of rat slc22a6 bound to alpha-ketoglutaric acid
25% identity, 85% coverage of query (65.5 bits)
PHT19_ARATH / Q9S735 Probable inorganic phosphate transporter 1-9; AtPht1;9; H(+)/Pi cotransporter from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
22% identity, 87% coverage of query (64.7 bits)
GudP / b2789 galactarate/D-glucarate transporter GudP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gudP / Q46916 galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 5 papers)
GUDP_ECOLI / Q46916 Probable galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.14.40 / C4ZZU4 Glucarate transporter, GudP. Encoded in an operon with GudD, a glucarate dehydratase from Escherichia coli (strain K12 / MC4100 / BW2952)
21% identity, 78% coverage of query (64.3 bits)
GlpT / b2240 sn-glycerol 3-phosphate:phosphate antiporter from Escherichia coli K-12 substr. MG1655 (see 24 papers)
glpT / P08194 sn-glycerol 3-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 48 papers)
TC 2.A.1.4.3 / P08194 Glycerol-P:Pi antiporter (may function by a 'rocker switch' mechanism; Law et al., 2007). The 3-d structure is known (3.3Å resolution) (Huang et al., 2003; Lemieux et al., 2005; Lemieux, 2007) from Escherichia coli (see 7 papers)
22% identity, 80% coverage of query (63.2 bits)
S22AL_MOUSE / Q9WTN6 Solute carrier family 22 member 21; Organic cation/carnitine transporter 3; Solute carrier family 22 member 9 from Mus musculus (Mouse) (see 3 papers)
TC 2.A.1.19.41 / Q9WTN6 Organocation transporter, OCTN3. Identified only in mouse; mediates carnitine transport (Pochini et al. 2013). 81% identical to 2.A.1.19.3. Also called SLC22a21 and SLC22a9 from Mus musculus
26% identity, 73% coverage of query (63.2 bits)
8bvtA / O35956 Cryo-em structure of rat slc22a6 bound to probenecid (see paper)
25% identity, 85% coverage of query (63.2 bits)
8et8A Cryo-em structure of the organic cation transporter 1 in complex with verapamil
26% identity, 73% coverage of query (63.2 bits)
8et7A / O15245 Cryo-em structure of the organic cation transporter 1 in complex with diphenhydramine (see paper)
26% identity, 73% coverage of query (63.2 bits)
8bvsA Cryo-em structure of rat slc22a6 bound to tenofovir
25% identity, 85% coverage of query (63.2 bits)
S22A6_PSEAM / O57379 Solute carrier family 22 member 6; Organic anion transporter 1; Renal organic anion transporter 1; ROAT1; fROAT1 from Pseudopleuronectes americanus (Winter flounder) (Pleuronectes americanus) (see paper)
22% identity, 75% coverage of query (62.8 bits)
S22A6_MOUSE / Q8VC69 Solute carrier family 22 member 6; Kidney-specific transport protein; Novel kidney transcript; mNKT; Organic anion transporter 1; mOAT1; Renal organic anion transporter 1; mROAT1 from Mus musculus (Mouse) (see 6 papers)
25% identity, 85% coverage of query (60.1 bits)
S22A6_HUMAN / Q4U2R8 Solute carrier family 22 member 6; Organic anion transporter 1; hOAT1; PAH transporter; hPAHT; Renal organic anion transporter 1; hROAT1 from Homo sapiens (Human) (see 20 papers)
TC 2.A.1.19.31 / Q4U2R8 Solute carrier family 22 member 6 (Organic anion transporter 1) (hOAT1) (PAH transporter) (hPAHT) (Renal organic anion transporter 1) (hROAT1), from Homo sapiens (see 17 papers)
24% identity, 85% coverage of query (58.5 bits)
S22A5_HUMAN / O76082 Organic cation/carnitine transporter 2; High-affinity sodium-dependent carnitine cotransporter; Solute carrier family 22 member 5 from Homo sapiens (Human) (see 28 papers)
TC 2.A.1.19.3 / O76082 The polyspecific organic cation (L- and D-carnitine, butyryl-L-carnitine, acetyl carnitine, γ-butyro-betaine, glycinebetaine, β-lactam antibiotics with a quaternary nitrogen such as cephaloridine, and others):Na+ symporter, OCTN2 (SLC22A5). Carnitine is transporter with high affinity (2 - 20 μM0 (Ingoglia et al. 2015). Associated with Crohn''s disease (Barton et al., 2005) as well as primary carnitine deficiency from Homo sapiens (Human) (see 28 papers)
22% identity, 81% coverage of query (57.4 bits)
S22A1_HUMAN / O15245 Solute carrier family 22 member 1; Organic cation transporter 1; hOCT1 from Homo sapiens (Human) (see 26 papers)
TC 2.A.1.19.29 / O15245 Solute carrier family 22 member 1 (Organic cation transporter 1) (hOCT1) from Homo sapiens (see 18 papers)
26% identity, 73% coverage of query (55.5 bits)
S22AE_HUMAN / Q9Y267 Solute carrier family 22 member 14; Organic cation transporter-like 4; ORCTL-4 from Homo sapiens (Human) (see 2 papers)
TC 2.A.1.19.22 / Q9Y267 solute carrier family 22, member 14, Slc22a14, is crucial for sperm motility and male fertility in mice. It is expressed specifically in male germ cells, and mice lacking the Slc22a14 gene show severe male infertility as well as sperm morphological changes from Homo sapiens (see 5 papers)
24% identity, 78% coverage of query (50.1 bits)
8fvzA / A8N031 Pipt y150a
24% identity, 92% coverage of query (47.8 bits)
S22A2_RABIT / Q8MJI6 Solute carrier family 22 member 2; Organic cation transporter 2 from Oryctolagus cuniculus (Rabbit) (see paper)
24% identity, 84% coverage of query (47.0 bits)
S22A2_HUMAN / O15244 Solute carrier family 22 member 2; Organic cation transporter 2; hOCT2 from Homo sapiens (Human) (see 25 papers)
TC 2.A.1.19.30 / O15244 Solute carrier family 22 member 2 (Organic cation transporter 2) (hOCT2) from Homo sapiens (see 23 papers)
22% identity, 73% coverage of query (45.8 bits)
7zhaA / O75751 Structure of human oct3 in complex with inhibitor decynium-22 (see paper)
23% identity, 84% coverage of query (45.4 bits)
7zh6A Structure of human oct3 in complex with inhibitor corticosterone
23% identity, 84% coverage of query (45.1 bits)
Or start over
Lawrence Berkeley National Laboratory