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Searching for up to 100 curated homologs for Ga0059261_0918 FitnessBrowser__Korea:Ga0059261_0918 (135 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 4.A.6.1.10 / Q04GK1 Phosphotransferase system, mannose/fructose-specific component IIA, component of The hexose (glucose and fructose demonstrated) PTS uptake system from Oenococcus oeni (strain BAA-331 / PSU-1) (see paper)
    33% identity, 96% coverage of query (80.9 bits)

TC 4.A.6.1.6 / Q2QKM4 ManL aka EIIAB, component of Glucose porter, ManLMN from Lactobacillus casei (see paper)
    32% identity, 98% coverage of query (80.5 bits)

TC 4.A.6.1.15 / E1UCI0 PTS system, mannose-specific, IIAB component, component of The primary glucose /mannose uptake transporter, ManLMN from Listeria monocytogenes serotype 4a (strain L99)
    37% identity, 84% coverage of query (80.1 bits)

TC 4.A.6.1.18 / B3W757 Phosphotransferase system sugar-specific EII component, component of Uptake porter/group translocator of galacto N-biose (Gal-β-1,3-GalNAc: galactose linked β-1,3 to N-acetylgalactosamine), lacto N-biose (Gal-β-1,3-GlcNAc: galactose linked β-1,3 to N-acetylglucosamine), and D-N-acetylgalactosamine (Bidart et al. 2014). The system is designated the GnbABCD system where GnbA = IIA, GnbB = IIB, GnbC = IIC, and GnbD = IID of the mannose-type PTS Enzyme II complex from Lactobacillus casei (strain BL23)
    36% identity, 92% coverage of query (73.9 bits)

TC 4.A.6.1.25 / CAQ67974.1 CAQ67974.1 PTS system, mannose-specific IIAB component, component of D-ribitol (D-aldonitol) (a pentitol) PTS Enzyme II complex RtlABCD from Lactobacillus casei BL23
    35% identity, 85% coverage of query (71.2 bits)

1vrcB / P69797 Complex of enzyme iiamannose and the histidine-containing phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure (see paper)
    35% identity, 89% coverage of query (70.1 bits)

ManX / b1817 mannose-specific PTS enzyme IIAB component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655 (see 12 papers)
manX / P69797 mannose-specific PTS enzyme IIAB component from Escherichia coli (strain K12) (see 9 papers)
PTNAB_ECOLI / P69797 PTS system mannose-specific EIIAB component; EIIAB-Man; EIII-Man; EC 2.7.1.191 from Escherichia coli (strain K12) (see 10 papers)
TC 4.A.6.1.1 / P69797 PTNA aka MANX aka PTSL aka GPTB aka B1817, component of The mannose (glucose, 2-deoxyglucose, glucosamine, N-acetylglucosamine, N-acetylmannosamine, mannosamine and fructose) PTS porter/group translocator, ManXYZ (Rephaeli and Saier 1980; Plumbridge 2015). Catalyzes xylose facilitated diffusion in lactobacilli. The order of D-sugar substrate affinities is: glucose > mannose > 2-deoxyglucose > N-acetylglucosamine > glucosamine > N-acetylmannosamine > mannosamine > fructose from Escherichia coli (see 10 papers)
manX / RF|NP_416331.1 PTS system mannose-specific EIIAB component; EC 2.7.1.-; EC 2.7.1.69 from Escherichia coli K12 (see 10 papers)
    35% identity, 89% coverage of query (69.3 bits)

Build an alignment

Build an alignment for Ga0059261_0918 and 7 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 4.A.6.1.16 / Q8Y8V8 Lmo0784 protein, component of Constitutively synthesized sensor, MpoABCD, controlling man operon (see TC# 4.A.6.1.15) expression by interacting with and phosphorylating ManR, the transcriptional regulator of the man operon from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
    29% identity, 87% coverage of query (68.2 bits)

agaF / Q8XAC4 AgaF (EC 2.7.1.193) from Escherichia coli O157:H7 (see 4 papers)
    31% identity, 97% coverage of query (63.2 bits)

TC 4.A.6.1.11 / D2BKY7 Mannose-specificPTS system, IIAB component, component of Mannose enzyme II complex, IIAB, IIC, IID. IIC/IID serve allows entry of some bacteriocins including pediocin (class IIa) and lactococcin A (class IIc) (Kjos et al., 2011). Transports and phosphorylates Glucose, Mannose and Glucosamine from Lactococcus lactis subsp. lactis (strain KF147) (see 2 papers)
    34% identity, 72% coverage of query (62.0 bits)

Q9S4L5 protein-Npi-phosphohistidine-D-mannose phosphotransferase (EC 2.7.1.191) from Streptococcus salivarius (see paper)
    33% identity, 72% coverage of query (60.8 bits)

TC 4.A.6.1.8 / Q82ZC8 PTS system, IIA component, component of The gluconate PTS uptake system. IIAGnt and IIBGnt form a high affinity 2:2 heterotetrameric complex from Enterococcus faecalis (see paper)
    34% identity, 73% coverage of query (60.5 bits)

TC 4.A.6.1.7 / Q5M5W6 ManL, component of The glucose/mannose/2-deoxyglucose/fructose phosphotransferase systems (phosphorylates without transport), ManLMN from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
    29% identity, 72% coverage of query (60.1 bits)

AgaX / b0129 putative PTS enzyme IIA component YadI from Escherichia coli K-12 substr. MG1655 (see 3 papers)
yadI / P36881 putative PTS enzyme IIA component YadI from Escherichia coli (strain K12) (see 2 papers)
    35% identity, 81% coverage of query (59.7 bits)

PTRA_LACCA / Q9RGG5 PTS system sorbose-specific EIIA component; EIIA-Sor; Sorbose-specific phosphotransferase enzyme IIA component from Lacticaseibacillus casei (Lactobacillus casei) (see paper)
Q9RGG5 protein-Npi-phosphohistidine-L-sorbose phosphotransferase (subunit 4/4) (EC 2.7.1.206) from Lacticaseibacillus casei (see paper)
    29% identity, 93% coverage of query (58.2 bits)

TC 4.A.6.1.9 / Q97N91 PTS system, IIA component, component of The fucose PTS uptake transporter, IIA/IIB/IIC/IIDFuc (FcsABCD) (Manzoor et al. 2015). Expression in response to fucose is under the control of the FcsR transcriptional activator, and its DNA binding site has been identified from Streptococcus pneumoniae (see paper)
    28% identity, 86% coverage of query (58.2 bits)

PTFA_BACSU / P26379 PTS system fructose-specific EIIA component; EIIA-Fru; Fructose-specific phosphotransferase enzyme IIA component; lev-PTS; p16 from Bacillus subtilis (strain 168) (see 3 papers)
TC 4.A.6.1.2 / P26379 PTFA aka LEVD aka SACL, component of Fructose group translocator, LevDEFG from Bacillus subtilis (see 3 papers)
    24% identity, 96% coverage of query (53.5 bits)

gfrA / A0A0F6BB77 fructoselysine/glucoselysine PTS enzyme IIA component from Salmonella typhimurium (strain 14028s / SGSC 2262) (see paper)
TC 4.A.6.1.19 / V7IHL6 PTS system fructose IIA component, component of PTS uptake system for glucoselysine and fructoselysine, GfrABCD from Salmonella enterica subsp. enterica serovar Cubana str. 76814
    22% identity, 96% coverage of query (50.1 bits)

dgaA / A0A0F6B8S8 D-glucosaminate PTS permease components EIIA (EC 2.7.1.203) from Salmonella typhimurium (strain 14028s / SGSC 2262) (see paper)
TC 4.A.6.1.17 / D0ZLR7 Putative phosphotransferase system enzyme IIA, component of D-glucosaminate group translocating uptake porter, DgaABCD (IIA-141 aas, IIB-161 aas, IIC-249 aas, and IID-285 aas, respectively) from Salmonella typhimurium (strain 14028s / SGSC 2262)
    30% identity, 87% coverage of query (48.5 bits)

TC 4.A.6.1.14 / Q8DR78 Phosphotransferase system sugar-specific EII component, component of Probable PTS uptake porter (IIA - IID) of disaccharides of gluconate and N-acetyglucosamine derived from degradation of hyaluronate and chondroitin by hyaluronidase (Marion et al. 2012). The cytoplasmic disaccharide may be hydrolyzed by the enzyme Ugl from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    31% identity, 81% coverage of query (46.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory