Searching for up to 100 curated homologs for Ga0059261_1576 FitnessBrowser__Korea:Ga0059261_1576 (289 a.a.)
Found high-coverage hits (≥70%) to 60 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
MTAP_RHORT / Q2RXH9 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; EC 2.4.2.28 from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1) (see 2 papers)
54% identity, 98% coverage of query (299 bits)
flB / Q1EMV9 5'-fluoro-5'-deoxy-adenosine phosphorylase (EC 2.4.2.1) from Streptantibioticus cattleyicolor (see paper)
flB / CAJ20005.1 5'-fluoro-5'-deoxy-adenosine phosphorylase from Streptomyces cattleya (see paper)
52% identity, 94% coverage of query (261 bits)
C6KFA4 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from uncultured bacterium (see paper)
47% identity, 90% coverage of query (247 bits)
4gljA / C6KFA4 Crystal structure of methylthioadenosine phosphorylase in complex with rhodamine b (see paper)
47% identity, 90% coverage of query (247 bits)
MTAP_SACS2 / Q97W94 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPII; EC 2.4.2.28 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 2 papers)
Q97W94 purine-nucleoside phosphorylase (EC 2.4.2.1); S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Saccharolobus solfataricus (see 3 papers)
3t94A / Q97W94 Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase (mtap) ii complexed with 5'-deoxy-5'-methylthioadenosine and sulfate (see paper)
46% identity, 90% coverage of query (235 bits)
5eubA Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with 2-amino-mta and sulfate
44% identity, 84% coverage of query (225 bits)
MTAP / Q13126 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Homo sapiens (see 5 papers)
MTAP_HUMAN / Q13126 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; EC 2.4.2.28 from Homo sapiens (Human) (see 6 papers)
Q13126 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Homo sapiens (see 8 papers)
44% identity, 84% coverage of query (224 bits)
5tc5A / Q13126 Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with butylthio-dadme-immucillin-a and chloride
44% identity, 84% coverage of query (224 bits)
6dz3A Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with (3r,4s)-1-((4-amino-5h-pyrrolo[3,2- d]pyrimidin-7-yl)methyl)-4-(((3-(1-butyl-1h-1,2,3-triazol-4-yl) propyl)thio)methyl)pyrrolidin-3-ol
44% identity, 84% coverage of query (224 bits)
6dyzA Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with (3r,4s)-1-((4-amino-5h-pyrrolo[3,2- d]pyrimidin-7-yl)methyl)-4-((prop-2-yn-1-ylthio)methyl)pyrrolidin-3- ol
44% identity, 84% coverage of query (224 bits)
5tc8A Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with methylthio-dadme-immucillin-a
44% identity, 84% coverage of query (224 bits)
5tc6A Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with propylthio-immucillin-a
44% identity, 84% coverage of query (224 bits)
3ozcA Crystal structure of human 5'-deoxy-5'-methyladenosine phosphorylase in complex with pcl-phenylthiodadmeimma
44% identity, 84% coverage of query (224 bits)
6dz0A Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with (3r,4s)-1-((4-amino-5h-pyrrolo[3,2- d]pyrimidin-7-yl)methyl)-4-((pent-4-yn-1-ylthio)methyl)pyrrolidin-3- ol
44% identity, 84% coverage of query (224 bits)
1wtaA / Q9YAQ8 Crystal structure of 5'-deoxy-5'-methylthioadenosine from aeropyrum pernix (r32 form)
48% identity, 87% coverage of query (220 bits)
Q9CQ65 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Mus musculus (see paper)
43% identity, 84% coverage of query (219 bits)
1sd2A Structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase complexed with 5'-methylthiotubercidin
45% identity, 84% coverage of query (218 bits)
1k27A Crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with a transition state analogue
44% identity, 84% coverage of query (217 bits)
6dz2A Crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with (3r,4s)-1-((4-amino-5h-pyrrolo[3,2- d]pyrimidin-7-yl)methyl)-4-(((3-(1-benzyl-1h-1,2,3-triazol-4-yl) propyl)thio)methyl)pyrrolidin-3-ol
43% identity, 84% coverage of query (214 bits)
1sd1A Structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase complexed with formycin a
43% identity, 84% coverage of query (214 bits)
1cg6A Structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase complexed with 5'-deoxy-5'-methylthioadenosine and sulfate at 1.7 a resolution
43% identity, 84% coverage of query (214 bits)
1cb0A Structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 a resolution
43% identity, 84% coverage of query (214 bits)
MTAP_PYRFU / Q8U4Q8 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; PfMTAP; EC 2.4.2.28 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see 3 papers)
Q8U4Q8 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Pyrococcus furiosus (see paper)
43% identity, 86% coverage of query (213 bits)
pnp / Q5JEQ6 adenosine phosphorylase (EC 2.4.2.1) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see paper)
MTAP_THEKO / Q5JEQ6 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; Nucleoside phosphorylase; EC 2.4.2.28 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
44% identity, 85% coverage of query (210 bits)
MTAP_SCHPO / Q09816 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; EC 2.4.2.28 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
44% identity, 81% coverage of query (204 bits)
MTAP_BOVIN / Q3MHF7 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; EC 2.4.2.28 from Bos taurus (Bovine) (see paper)
43% identity, 84% coverage of query (201 bits)
5f7jB / I0B503 Crystal structure of mutant n87t of adenosine/methylthioadenosine phosphorylase from schistosoma mansoni in complex with adenine (see paper)
40% identity, 83% coverage of query (200 bits)
I0B503 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Schistosoma mansoni (see paper)
40% identity, 83% coverage of query (200 bits)
5f76A Crystal structure of mutant s12t of adenosine/methylthioadenosine phosphorylase from schistosoma mansoni in complex with methylthioadenosine
39% identity, 81% coverage of query (190 bits)
4l5aA Methylthioadenosine phosphorylase from schistosoma mansoni in complex with tubercidin
40% identity, 81% coverage of query (189 bits)
MTAP_DROME / Q9V813 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; EC 2.4.2.28 from Drosophila melanogaster (Fruit fly) (see paper)
40% identity, 81% coverage of query (183 bits)
PNPH_PYRFU / Q8U2I1 6-oxopurine nucleoside phosphorylase; Purine nucleoside phosphorylase; PNP; PfPNP; EC 2.4.2.1 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see 2 papers)
Q8U2I1 purine-nucleoside phosphorylase (EC 2.4.2.1) from Pyrococcus furiosus (see 2 papers)
39% identity, 89% coverage of query (178 bits)
MTAP_YEAST / Q07938 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; MTAPase; Multicopy enhancer of UAS2; EC 2.4.2.28 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
37% identity, 83% coverage of query (178 bits)
MTAP_MYCS2 / A0QR54 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; EC 2.4.2.28 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
40% identity, 91% coverage of query (170 bits)
salT / B0L7E7 chloro-purine nucleoside phosphorylase (EC 2.4.2.1) from Salinispora tropica (see paper)
B0L7E7 purine-nucleoside phosphorylase (EC 2.4.2.1) from Salinispora tropica (see paper)
39% identity, 96% coverage of query (169 bits)
TK1482 / Q5JJB8 guanosine phosphorylase (EC 2.4.2.15) from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (see paper)
PNPH_THEKO / Q5JJB8 Probable 6-oxopurine nucleoside phosphorylase; Purine nucleoside phosphorylase; PNP; EC 2.4.2.1 from Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1)) (see paper)
37% identity, 89% coverage of query (169 bits)
MTAP_MYCTU / O06401 S-methyl-5'-thioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase; MTA phosphorylase; MTAP; EC 2.4.2.28 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
O06401 S-methyl-5'-thioadenosine phosphorylase (EC 2.4.2.28) from Mycobacterium tuberculosis (see paper)
38% identity, 88% coverage of query (157 bits)
PA3004 / Q9HZK1 S-methyl-5'-thioinosine phosphorylase monomer (EC 2.4.2.44) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
MTIP_PSEAE / Q9HZK1 S-methyl-5'-thioinosine phosphorylase; 5'-methylthioinosine phosphorylase; MTI phosphorylase; MTIP; EC 2.4.2.44 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
Q9HZK1 S-methyl-5'-thioinosine phosphorylase (EC 2.4.2.44) from Pseudomonas aeruginosa (see paper)
36% identity, 83% coverage of query (142 bits)
3ozbA / Q9HZK1 Crystal structure of 5'-methylthioinosine phosphorylase from psedomonas aeruginosa in complex with hypoxanthine (see paper)
35% identity, 82% coverage of query (132 bits)
Build an alignment for Ga0059261_1576 and 39 homologs with ≥ 30% identity
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4lnaA / D2QIK7 Crystal structure of purine nucleoside phosphorylase i from spirosoma linguale dsm 74, nysgrc target 029362
23% identity, 83% coverage of query (55.1 bits)
3e9rB Crystal structure of purine nucleoside phosphorylase from schistosoma mansoni in complex with adenine
26% identity, 81% coverage of query (55.1 bits)
3lbaA / Q8DTU4 The crystal structure of smu.1229 from streptococcus mutans ua159 bound to hypoxanthine
24% identity, 83% coverage of query (54.7 bits)
3iexA Schistosoma purine nucleoside phosphorylase in complex with guanosine
26% identity, 73% coverage of query (54.7 bits)
PNPH_SCHPO / Q9UTG1 Putative purine nucleoside phosphorylase; PNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
25% identity, 81% coverage of query (53.1 bits)
3e0qC / Q9BMI9 Crystal structure of schistosoma mansoni purine nucleoside phosphorylase complexed with a novel monocyclic inhibitor (see paper)
26% identity, 73% coverage of query (52.4 bits)
3khsB / Q5YBA4 Crystal structure of grouper iridovirus purine nucleoside phosphorylase (see paper)
28% identity, 73% coverage of query (52.4 bits)
1tcvA Crystal structure of the purine nucleoside phosphorylase from schistosoma mansoni in complex with non-detergent sulfobetaine 195 and acetate
24% identity, 77% coverage of query (52.4 bits)
4m1eB / D5SMY7 Crystal structure of purine nucleoside phosphorylase i from planctomyces limnophilus dsm 3776, nysgrc target 029364.
23% identity, 83% coverage of query (52.0 bits)
Q9BMI9 purine-nucleoside phosphorylase (EC 2.4.2.1) from Schistosoma mansoni (see 2 papers)
26% identity, 73% coverage of query (52.0 bits)
3fazA Crystal structure of schistosoma mansoni purine nucleoside phosphorylase in complex with inosine
25% identity, 73% coverage of query (51.6 bits)
1tcuA Crystal structure of the purine nucleoside phosphorylase from schistosoma mansoni in complex with phosphate and acetate
25% identity, 73% coverage of query (51.6 bits)
3e9zA Crystal structure of purine nucleoside phosphorylase from schistosoma mansoni in complex with 6-chloroguanine
25% identity, 73% coverage of query (51.6 bits)
3djfA Crystal structure of schistosoma mansoni purine nucleoside phosphorylase in a complex with bcx-34
25% identity, 73% coverage of query (51.6 bits)
3fb1A Crystal structure of purine nucleoside phosphorylase in complex with ribose-1-phosphate
25% identity, 73% coverage of query (51.6 bits)
3fnqA Crystal structure of schistosoma purine nucleoside phosphorylase in complex with hypoxanthine
25% identity, 73% coverage of query (51.6 bits)
3f8wA Crystal structure of schistosoma mansoni purine nucleoside phosphorylase in complex with adenosine
25% identity, 73% coverage of query (51.6 bits)
8swtA / Q5LAA3 Structure of bacteroides fragilis pnp bound to transition state analog immucillin h and sulfate (see paper)
24% identity, 73% coverage of query (49.7 bits)
2p4sA / A4Q998 Structure of purine nucleoside phosphorylase from anopheles gambiae in complex with dadme-immh (see paper)
24% identity, 80% coverage of query (47.4 bits)
PNPH_ANOGA / A4Q998 Purine nucleoside phosphorylase; AgPNP; Inosine phosphorylase; Inosine-guanosine phosphorylase; EC 2.4.2.1 from Anopheles gambiae (African malaria mosquito) (see paper)
24% identity, 80% coverage of query (46.2 bits)
3odgA / Q66D48 Crystal structure of xanthosine phosphorylase bound with xanthine from yersinia pseudotuberculosis
24% identity, 85% coverage of query (45.8 bits)
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Lawrence Berkeley National Laboratory