Sites on a Tree

 

Searching for up to 100 curated homologs for Ga0059261_1586 FitnessBrowser__Korea:Ga0059261_1586 (475 a.a.)

Found high-coverage hits (≥70%) to 8 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

THRC_METAC / Q8TQD4 Threonine synthase; TS; EC 4.2.3.1 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
GB|AAM05023.1 threonine synthase; EC 4.2.3.1 from Methanosarcina acetivorans C2A (see paper)
    35% identity, 80% coverage of query (210 bits)

P83823 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see paper)
Q5SL02 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see 2 papers)
3aexA / Q5SL02 Catalytic intermediate analogue of threonine synthase from thermus thermophilus hb8 (see paper)
    35% identity, 70% coverage of query (136 bits)

1uimA Crystal structure of threonine synthase from thermus thermophilus hb8, orthorhombic crystal form
    35% identity, 70% coverage of query (136 bits)

1v7cA Crystal structure of threonine synthase from thermus thermophilus hb8 in complex with a substrate analogue
    35% identity, 70% coverage of query (136 bits)

thrC / CAA82669.1 threonine synthase from Bacillus sp. (see paper)
    35% identity, 71% coverage of query (132 bits)

Build an alignment

Build an alignment for Ga0059261_1586 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

THRC1_ARATH / Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    26% identity, 98% coverage of query (129 bits)

2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine
    27% identity, 81% coverage of query (126 bits)

2c2gA / Q9S7B5 Crystal structure of threonine synthase from arabidopsis thaliana in complex with its cofactor pyridoxal phosphate (see paper)
    27% identity, 81% coverage of query (119 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory