Searching for up to 100 curated homologs for Ga0059261_1901 FitnessBrowser__Korea:Ga0059261_1901 (423 a.a.)
Found high-coverage hits (≥70%) to 45 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ExuT / b3093 hexuronate transporter from Escherichia coli K-12 substr. MG1655 (see 5 papers)
exuT / P0AA78 hexuronate transporter from Escherichia coli (strain K12) (see 3 papers)
EXUT_ECOLI / P0AA78 Hexuronate transporter; Aldohexuronate transport system from Escherichia coli (strain K12) (see 5 papers)
33% identity, 100% coverage of query (222 bits)
TC 2.A.1.14.2 / P0AA78 Hexuronate (glucuronate; galacturonate) porter, ExuT (Nemoz et al. 1976). It also transports D-glucose (HJ Kim et al., Front. Microbiol., 23 January 2020) from Escherichia coli (see 3 papers)
33% identity, 100% coverage of query (222 bits)
HSERO_RS23010 D-galacturonate transporter ExuT from Herbaspirillum seropedicae SmR1
33% identity, 93% coverage of query (217 bits)
EXUT_DICCH / P94774 Galacturonate transporter from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see 3 papers)
TC 2.A.1.14.41 / P94774 The Aldohexuronate (glucuronate, galacturonate) uptake porter from Dickeya chrysanthemi
exuT / AAB70881.1 exuT from Dickeya chrysanthemi (see paper)
35% identity, 74% coverage of query (213 bits)
Pf1N1B4_5129 D-galacturonate transporter ExuT from Pseudomonas fluorescens FW300-N1B4
33% identity, 85% coverage of query (190 bits)
CA265_RS19855 D-galacturonate transporter ExuT from Pedobacter sp. GW460-11-11-14-LB5
30% identity, 77% coverage of query (171 bits)
Build an alignment for Ga0059261_1901 and 6 homologs with ≥ 30% identity
Or download the sequences
BT4105 D-galacturonate transporter ExuT from Bacteroides thetaiotaomicron VPI-5482
29% identity, 85% coverage of query (162 bits)
LgoT / b4356 galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lgoT / P39398 galactonate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
LGOT_ECOLI / P39398 Probable L-galactonate transporter; Galactonate:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
yjjL / RF|NP_418776 inner membrane transport protein yjjL from Escherichia coli K12 (see 2 papers)
30% identity, 78% coverage of query (159 bits)
GarP / b3127 galactarate/D-glucarate transporter GarP from Escherichia coli K-12 substr. MG1655 (see 6 papers)
garP / P0AA80 galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 5 papers)
GARP_ECOLI / P0AA80 Probable galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 2 papers)
31% identity, 79% coverage of query (155 bits)
TC 2.A.1.14.14 / Q8FDB7 Probable D-galactarate (glucarate?):H+ symporter, GarP or YhaU from Escherichia coli O6 (see paper)
31% identity, 79% coverage of query (155 bits)
SAUU_CUPNH / Q0K843 Probable sulfoacetate transporter SauU from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
29% identity, 93% coverage of query (152 bits)
PS417_04205 D-galacturonate transporter (MFS superfamily) from Pseudomonas simiae WCS417
31% identity, 73% coverage of query (152 bits)
YidT / b3691 D-galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 9 papers)
dgoT / P0AA76 D-galactonate:H+ symporter from Escherichia coli (strain K12) (see 11 papers)
DGOT_ECOLI / P0AA76 D-galactonate transporter; D-galactonate/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.14.7 / P0AA76 Galactonate transporter from Escherichia coli (see 4 papers)
30% identity, 79% coverage of query (150 bits)
6e9nA / J7QAK3 E. Coli d-galactonate:proton symporter in the inward open form (see paper)
30% identity, 79% coverage of query (149 bits)
GUDP_BACSU / P42237 Probable galactarate/D-glucarate transporter GudP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.14.1 / P42237 Glucarate porter from Bacillus subtilis (see 3 papers)
28% identity, 78% coverage of query (142 bits)
GudP / b2789 galactarate/D-glucarate transporter GudP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gudP / Q46916 galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 5 papers)
GUDP_ECOLI / Q46916 Probable galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.14.40 / C4ZZU4 Glucarate transporter, GudP. Encoded in an operon with GudD, a glucarate dehydratase from Escherichia coli (strain K12 / MC4100 / BW2952)
28% identity, 74% coverage of query (141 bits)
6e9oA E. Coli d-galactonate:proton symporter mutant e133q in the outward substrate-bound form
27% identity, 79% coverage of query (117 bits)
ANTR4_ARATH / Q66GI9 Probable anion transporter 4, chloroplastic; Phosphate transporter PHT4;3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
29% identity, 91% coverage of query (112 bits)
ANTR2_ARATH / Q8GX78 Ascorbate transporter, chloroplastic; Phosphate transporter PHT4;4; AtPHT4;4; Probable anion transporter 2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
25% identity, 93% coverage of query (108 bits)
AO356_28540 D-mannose transporter from Pseudomonas fluorescens FW300-N2C3
25% identity, 95% coverage of query (102 bits)
ANTR1_ARATH / O82390 Sodium-dependent phosphate transport protein 1, chloroplastic; Anion transporter 1; Na(+)/PI cotransporter 1; Phosphate transporter PHT4;1; Sodium/phosphate cotransporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
O82390 ABC-type phosphate transporter (EC 7.3.2.1) from Arabidopsis thaliana (see 2 papers)
TC 2.A.1.14.22 / O82390 The chloroplast thylakoid Na+:phosphate symporter, ANTR1 (512aas) (Pavón et al., 2008). Residues essential for function have been identified from Arabidopsis thaliana (see 7 papers)
25% identity, 88% coverage of query (102 bits)
ANTR3_ARATH / Q7XJR2 Probable anion transporter 3, chloroplastic; Phosphate transporter PHT4;2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q7XJR2 ABC-type phosphate transporter (EC 7.3.2.1) from Arabidopsis thaliana (see paper)
26% identity, 88% coverage of query (99.0 bits)
S17A5_HUMAN / Q9NRA2 Sialin; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; AST; Membrane glycoprotein HP59; Solute carrier family 17 member 5; Vesicular excitatory amino acid transporter; VEAT from Homo sapiens (Human) (see 10 papers)
TC 2.A.1.14.10 / Q9NRA2 Lysosomal sialate transporter (Salla disease and infantile sialate storage disease protein (Morin et al., 2004)). Also transports glucuronic acid and aspartate. Structure-function studies have identify crucial residues and substrate-induced conformational changes (Courville et al., 2010). Also called SLC17A5. The substrate binding pocket has been identified based on modeling studies (see 8 papers)
26% identity, 71% coverage of query (98.6 bits)
S17A5_MOUSE / Q8BN82 Sialin; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; AST; Solute carrier family 17 member 5; Vesicular excitatory amino acid transporter; VEAT from Mus musculus (Mouse) (see 3 papers)
26% identity, 71% coverage of query (97.4 bits)
S17A5_RAT / Q5Q0U0 Sialin; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; AST; Solute carrier family 17 (Anion/sugar transporter), member 5; Vesicular excitatory amino acid transporter; VEAT from Rattus norvegicus (Rat) (see 2 papers)
25% identity, 71% coverage of query (95.1 bits)
S17A5_SHEEP / Q9MZD1 Sialin; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; AST; Membrane glycoprotein SP55; Solute carrier family 17 member 5; Vesicular excitatory amino acid transporter; VEAT from Ovis aries (Sheep) (see paper)
25% identity, 71% coverage of query (94.4 bits)
Q03567 Uncharacterized transporter slc-17.2 from Caenorhabditis elegans
26% identity, 75% coverage of query (94.4 bits)
TC 2.A.1.14.26 / F2YPN7 The plasma membrane Lethal (2)01810 glutamate uptake porter (Km=0.07μM) (Inhibited by aspartate) from Drosophila melanogaster
23% identity, 95% coverage of query (92.4 bits)
S17A9_RAT / P0DX21 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Rattus norvegicus (Rat) (see 2 papers)
24% identity, 87% coverage of query (89.7 bits)
ANTR5_ARATH / Q9FKV1 Probable anion transporter 5; Phosphate transporter PHT4;6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
24% identity, 89% coverage of query (86.7 bits)
S17A9_MOUSE / Q8VCL5 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Mus musculus (Mouse) (see 5 papers)
24% identity, 87% coverage of query (85.9 bits)
S17A9_HUMAN / Q9BYT1 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Homo sapiens (Human) (see 4 papers)
TC 2.A.1.14.21 / Q9BYT1 The vesicular purine nucleotide (ADP, ATP, GTP) transporter, VNUT or SLC17A9. It is found in synaptic vesicles and chromafin granules (Sawada et al., 2008)) and is associated with disseminated superficial actinic porokeratosis (DSAP), a rare autosomal dominant genodermatosis (Cui et al. 2014). It plays a key role in purinergic signaling through its ability to transport nucleotides using the pmf. It catalyzes Cl--dependent transport activity involving essential arginines in the transmembrane region. Ketoacids inhibit these transporters through modulation of Cl- activation, but Cl- and the arginine residues are not important for ATP binding (Iwai et al. 2019). High expression of SLC17A9 correlates with a poor prognosis for colorectal cancer from Homo sapiens (Human) (see 5 papers)
26% identity, 95% coverage of query (84.0 bits)
PS417_07265 2-deoxy-D-ribonate transporter 1 from Pseudomonas simiae WCS417
27% identity, 78% coverage of query (82.0 bits)
NPT3_MOUSE / Q5SZA1 Sodium-dependent phosphate transport protein 3; Na(+)/PI cotransporter 3; Sodium/phosphate cotransporter 3; Solute carrier family 17 member 2 from Mus musculus (Mouse) (see paper)
23% identity, 74% coverage of query (79.7 bits)
VGLU3_MOUSE / Q8BFU8 Vesicular glutamate transporter 3; VGluT3; Solute carrier family 17 member 8 from Mus musculus (Mouse) (see 5 papers)
TC 2.A.1.14.23 / Q8BFU8 Vesicular glutamate transporter #3 (VGLUT3) [Its absence in mice causes sensorineural deafness and seizures]. 70% identical to VGLUT2 (TC# 2.A.1.14.16) (Gras et al., 2002). VGLUT1-3 concentrate glutamate into synaptic vesicles before its exocytotic release and contribute to the regulation of serotonergic transmission and anxiety (Amilhon et al., 2010). It may catalyze uptake of the neurotransmitter coupled with H+ export and K+ uptake from Mus musculus (see 6 papers)
25% identity, 72% coverage of query (77.4 bits)
TC 2.A.1.14.8 / Q9RPP3 Phthalate porter from Burkholderia cepacia (Pseudomonas cepacia) (see paper)
21% identity, 82% coverage of query (71.6 bits)
TC 2.A.1.4.2 / P12681 P-glycerate:Pi antiporter, Pgt from Salmonella typhimurium (see 2 papers)
22% identity, 95% coverage of query (69.7 bits)
YfaV / b2246 putative transporter YfaV from Escherichia coli K-12 substr. MG1655 (see 4 papers)
TC 2.A.1.14.35 / P76470 Inner membrane transport protein RhmT from Escherichia coli (strain K12) (see 4 papers)
24% identity, 84% coverage of query (67.8 bits)
BWI76_RS23715 2-deoxy-D-ribonate transporter 1 from Klebsiella michiganensis M5al
25% identity, 80% coverage of query (67.4 bits)
NICT_PSEPK / Q88FY6 Putative metabolite transport protein NicT; Nicotinate degradation protein T from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
21% identity, 98% coverage of query (67.0 bits)
PFMAC_PESFW / W3X9K4 MFS transporter PfmaC; Conidial pigment biosynthesis cluster protein B from Pestalotiopsis fici (strain W106-1 / CGMCC3.15140) (see paper)
22% identity, 74% coverage of query (62.8 bits)
CH_124318 MFS transporter from Magnaporthe grisea 70-15 (see 2 papers)
24% identity, 72% coverage of query (61.6 bits)
Q9HTV5 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Pseudomonas aeruginosa (see paper)
22% identity, 96% coverage of query (61.6 bits)
SPIN_DROME / Q9GQQ0 Protein spinster; Protein benchwarmer; Protein diphthong from Drosophila melanogaster (Fruit fly) (see 3 papers)
TC 2.A.1.49.1 / Q9GQQ0 The spinster protein, spin1 or spns1 gene product (involved in synaptic growth regulation; interacts with Bcl-2/Bcl-xL, affecting programmed cell death) (see 6 papers)
spin / GI|12003970 protein spinster from Drosophila melanogaster (see paper)
23% identity, 80% coverage of query (52.0 bits)
MHBT_KLEOX / Q5EXK5 3-hydroxybenzoate transporter MhbT from Klebsiella oxytoca (see paper)
23% identity, 73% coverage of query (47.0 bits)
Or start over
Lawrence Berkeley National Laboratory