Searching for up to 100 curated homologs for Ga0059261_2137 FitnessBrowser__Korea:Ga0059261_2137 (597 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.210.2 / Q02592 The vacuolar heavy metal tolerance protein precursor, HMT1 (transports phytochelins and Cd2+·phytochelin complexes) from Schizosaccharomyces pombe (Fission yeast) (see 2 papers)
hmt1 / RF|NP_588371.3 heavy metal tolerance protein from Schizosaccharomyces pombe (see 2 papers)
34% identity, 84% coverage of query (287 bits)
Y1866_STAAM / Q99T13 Putative multidrug export ATP-binding/permease protein SAV1866; EC 7.6.2.- from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
Q99T13 ABC-type xenobiotic transporter (EC 7.6.2.2) from Staphylococcus aureus (see paper)
TC 3.A.1.106.2 / Q2G2M9 The homodimeric Sav1866 multidrug exporter (transports doxorubicin, verapamil, ethidium, tetraphenylphosphonium, vinblastine and the fluorescent dye, Hoechst 33342; 3-D structure known at 3 Å resolution; Dawson and Locher, 2006; Velamakanni et al., 2008) The empty site opens by rotation of the nucleotide-binding domain whereas the ATP-bound site remains occluded (Jones and George, 2011). Conformational changes induced by ATP-binding and hydrolysis have been proposed (Becker et al. 2010; Oliveira et al., 2011). The alternating access mechanism and the flippase activity of this ABC exporter has been shown to be lipid-dependent (Becker et al. 2010; Oliveira et al., 2011). The alternating access mechanism and the flippase activity of this ABC exporter has been shown to be lipid-dependent from Staphylococcus aureus (strain NCTC 8325)
2hydA / Q99T13 Multidrug abc transporter sav1866 (see paper)
33% identity, 82% coverage of query (283 bits)
2onjA Structure of the multidrug abc transporter sav1866 from s. Aureus in complex with amp-pnp
33% identity, 82% coverage of query (283 bits)
HMT1_CAEEL / G5EFD4 Heavy metal tolerance factor 1 from Caenorhabditis elegans (see 2 papers)
G5EFD4 ABC-type Cd2+ transporter (EC 7.2.2.2) from Caenorhabditis elegans (see paper)
TC 3.A.1.210.7 / Q9XUJ1 The homodimeric heavy metal tolerance protein 1, CeHMT-1 (AbcB6) (exports phytochelatin ((γ-Glu-Cys)n)-Cd2+ from Caenorhabditis elegans (see 2 papers)
31% identity, 91% coverage of query (273 bits)
msbA / Q2YJN8 lipid A-core oligosaccharide flippase (EC 7.5.2.6) from Brucella abortus (strain 2308) (see 2 papers)
34% identity, 81% coverage of query (269 bits)
TC 3.A.1.210.9 / Q1LRE9 The Ni2+/Co2+ exporter AtmA from Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
33% identity, 93% coverage of query (265 bits)
4mrnA / Q2G506 Structure of a bacterial atm1-family abc transporter (see paper)
36% identity, 82% coverage of query (265 bits)
ATM1_NOVAD / Q2G506 ATM1-type heavy metal exporter; ATP-binding cassette transporter Atm1; NaAtm1; EC 7.-.-.- from Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199) (see paper)
36% identity, 82% coverage of query (265 bits)
4mrvA Structure of a bacterial atm1-family abc transporter
36% identity, 82% coverage of query (265 bits)
4mrsA Structure of a bacterial atm1-family abc transporter
36% identity, 82% coverage of query (265 bits)
4mrpA Structure of a bacterial atm1-family abc transporter
36% identity, 82% coverage of query (265 bits)
6parA Structure of a bacterial atm1-family abc exporter with mgamppnp bound
36% identity, 82% coverage of query (265 bits)
6pamA Structure of a bacterial atm1-family abc transporter with mgadp bound
36% identity, 81% coverage of query (265 bits)
ABCB6_MESAU / A0A125QXJ1 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter; EC 7.6.2.5 from Mesocricetus auratus (Golden hamster) (see paper)
34% identity, 84% coverage of query (263 bits)
6panA Structure of a bacterial atm1-family abc exporter with atp bound
36% identity, 82% coverage of query (263 bits)
8k7bA Post-occluded structure of human abcb6 w546a mutant (adp/vo4-bound)
33% identity, 84% coverage of query (263 bits)
7dnyB Cryo-em structure of the human abcb6 (coproporphyrin iii-bound)
33% identity, 85% coverage of query (262 bits)
ABCB6_MOUSE / Q9DC29 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; EC 7.6.2.5 from Mus musculus (Mouse) (see 7 papers)
35% identity, 84% coverage of query (261 bits)
ABCB6_HUMAN / Q9NP58 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter; EC 7.6.2.5 from Homo sapiens (Human) (see 23 papers)
TC 3.A.1.210.6 / Q9NP58 Mitochondrial outer membrane/lysosome anionic porphyrin uptake half ABC transporter, ABCB6. Expressed in many mammalian tissues (including fetal liver) in response to intracellular porphyrin. Porphyrin uptake activates de novo porphyrin (haem) biosynthesis from Homo sapiens (Human) (see 7 papers)
ABCB6 / RF|NP_005680.1 ATP-binding cassette sub-family B member 6, mitochondrial from Homo sapiens (see paper)
33% identity, 85% coverage of query (260 bits)
7eklA Mitochondrial outer membrane protein
33% identity, 84% coverage of query (260 bits)
7dnzA / Q9NP58 Cryo-em structure of the human abcb6 (hemin and gsh-bound) (see paper)
33% identity, 84% coverage of query (259 bits)
7dnzB Cryo-em structure of the human abcb6 (hemin and gsh-bound)
33% identity, 84% coverage of query (259 bits)
ABCB7_HUMAN / O75027 Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette transporter 7; ABC transporter 7 protein from Homo sapiens (Human) (see 8 papers)
TC 3.A.1.210.4 / O75027 ABC7 or ABCB7 iron transporter (X-linked sideroblastis anemia protein, XLSA/A (Fujiwara and Harigae 2013)) from Homo sapiens (Human) (see 9 papers)
32% identity, 99% coverage of query (258 bits)
AB23B_ARATH / Q9FUT3 ABC transporter B family member 23, mitochondrial; ABC transporter ABCB.23; AtABCB23; ABC transporter of the mitochondrion 1; AtATM1; Iron-sulfur clusters transporter ATM1; Protein STARIK 2 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
32% identity, 83% coverage of query (258 bits)
ABCB1 / P08183 ATP-dependent translocase ABCB1 (EC 7.6.2.2) from Homo sapiens (see 39 papers)
MDR1_HUMAN / P08183 ATP-dependent translocase ABCB1; ATP-binding cassette sub-family B member 1; Multidrug resistance protein 1; P-glycoprotein 1; Phospholipid transporter ABCB1; CD243 antigen; EC 7.6.2.2; EC 7.6.2.1 from Homo sapiens (Human) (see 8 papers)
P08183 ABC-type xenobiotic transporter (EC 7.6.2.2); ABC-type glutathione-S-conjugate transporter (EC 7.6.2.3) from Homo sapiens (see 10 papers)
TC 3.A.1.201.1 / P08183 Broad specificity multidrug resistance (MDR1; MDR-1; Pgp; P-gp; ABCB1; P-glycoprotein) efflux pump. It exports organic cations and amphiphilic compounds of unrelated chemical structure from Homo sapiens (Human) (see 19 papers)
33% identity, 83% coverage of query (256 bits)
ABCB1 / RF|NP_000918.2 multidrug resistance protein 1 from Homo sapiens
33% identity, 83% coverage of query (256 bits)
STA1 / CAB97048.1 mitochondrial half-ABC transporter from Arabidopsis thaliana (see paper)
32% identity, 84% coverage of query (255 bits)
AB24B_ARATH / Q9M0G9 ABC transporter B family member 24, mitochondrial; ABC transporter ABCB.24; AtABCB24; ABC transporter of the mitochondrion 2; AtATM2; Iron-sulfur clusters transporter ATM2; Protein STARIK 3 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
31% identity, 83% coverage of query (255 bits)
ABCB7_RAT / Q704E8 Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette transporter 7; ABC transporter 7 protein from Rattus norvegicus (Rat) (see paper)
32% identity, 98% coverage of query (254 bits)
AB25B_ARATH / Q9LVM1 ABC transporter B family member 25, mitochondrial; ABC transporter ABCB.25; AtABCB25; ABC transporter of the mitochondrion 3; AtATM3; Iron-sulfur clusters transporter ATM3; Protein STARIK 1 from Arabidopsis thaliana (Mouse-ear cress) (see 6 papers)
TC 3.A.1.210.8 / Q9LVM1 Mitochondrial ABC transporter, ATM3, involved in iron homeostasis (Chen et al. 2007) and heavy metal resistance (Kim et al. 2006). There are three isoforms: ATM1, ATM2 and ATM3 (Chen et al., 2007). ATM3 can replace the yeast iron/sulfur cluster exporter better than ATM1 or ATM2. Atm3 is most similar to the human and yeast homologues, TC# 3.A.1.210.4 and 3.A.1.210.1, 51% and 47% identical, respectively from Arabidopsis thaliana (Mouse-ear cress) (see 11 papers)
GB|AAN13224.1 putative ABC transporter protein from Arabidopsis thaliana (see paper)
32% identity, 84% coverage of query (254 bits)
TC 3.A.1.135.5 / Q9WYC4 Uncharacterized ABC transporter ATP-binding protein TM_0288, component of The hetrodimeric ABC transporter, TM287/TM288 from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
30% identity, 98% coverage of query (253 bits)
6qexA / P08183 Nanodisc reconstituted human abcb1 in complex with uic2 fab and taxol (see paper)
33% identity, 82% coverage of query (253 bits)
7a6fA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and zosuquidar
33% identity, 82% coverage of query (253 bits)
7a6eA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and tariquidar
33% identity, 82% coverage of query (253 bits)
7a6cA Nanodisc reconstituted human abcb1 in complex with mrk16 fab and elacridar
33% identity, 82% coverage of query (253 bits)
7a69A Nanodisc reconstituted human abcb1 in complex with mrk16 fab and vincristine
33% identity, 82% coverage of query (253 bits)
7o9wA Encequidar-bound human p-glycoprotein in complex with uic2-fab
33% identity, 82% coverage of query (253 bits)
6c0vA Molecular structure of human p-glycoprotein in the atp-bound, outward- facing conformation
32% identity, 90% coverage of query (253 bits)
7n5aA Structure of atatm3 in the closed conformation
31% identity, 92% coverage of query (252 bits)
7n59A / Q9LVM1 Structure of atatm3 in the inward-facing conformation with gssg bound (see paper)
31% identity, 92% coverage of query (251 bits)
TC 3.A.1.210.5 / Q25693 Multidrug resistance homologues, Pfmdr2, protein from Plasmodium falciparum (see paper)
31% identity, 80% coverage of query (251 bits)
ACLQ_ASPOR / Q2UPC0 ABC transporter aclQ; Aspirochlorine biosynthesis protein Q from Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) (see paper)
32% identity, 93% coverage of query (251 bits)
YWJA_BACSU / P45861 Uncharacterized ABC transporter ATP-binding protein YwjA from Bacillus subtilis (strain 168) (see 2 papers)
31% identity, 94% coverage of query (251 bits)
MDR1_CRIGR / P21448 ATP-dependent translocase ABCB1; ATP-binding cassette sub-family B member 1; Multidrug resistance protein 1; P-glycoprotein 1; Phospholipid transporter ABCB1; CD243 antigen; EC 7.6.2.2; EC 7.6.2.1 from Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (see paper)
32% identity, 84% coverage of query (251 bits)
ABCB7_MOUSE / Q61102 Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial; ATP-binding cassette transporter 7; ABC transporter 7 protein from Mus musculus (Mouse) (see 4 papers)
31% identity, 98% coverage of query (251 bits)
MSBA_VIBCH / Q9KQW9 ATP-dependent lipid A-core flippase; Lipid A export ATP-binding/permease protein MsbA; EC 7.5.2.6 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) (see paper)
Q9KQW9 ABC-type lipopolysaccharide transporter (EC 7.5.2.5) from Vibrio cholerae (see paper)
38% identity, 72% coverage of query (251 bits)
MDR1A_MOUSE / P21447 ATP-dependent translocase ABCB1; ATP-binding cassette sub-family B member 1A; MDR1A; Multidrug resistance protein 1A; Multidrug resistance protein 3; P-glycoprotein 3; Phospholipid transporter ABCB1; EC 7.6.2.2; EC 7.6.2.1 from Mus musculus (Mouse) (see paper)
P21447 ABC-type xenobiotic transporter (EC 7.6.2.2) from Mus musculus (see paper)
32% identity, 83% coverage of query (251 bits)
MsbA / b0914 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli K-12 substr. MG1655 (see 54 papers)
msbA / P60752 ATP-binding lipopolysaccharide transport protein (EC 7.5.2.6) from Escherichia coli (strain K12) (see 57 papers)
MSBA_ECOLI / P60752 ATP-dependent lipid A-core flippase; Lipid A export ATP-binding/permease protein MsbA; Lipid flippase; EC 7.5.2.6 from Escherichia coli (strain K12) (see 17 papers)
P60752 ABC-type lipid A-core oligosaccharide transporter (EC 7.5.2.6); P-type phospholipid transporter (EC 7.6.2.1) from Escherichia coli (see 13 papers)
TC 3.A.1.106.1 / P60752 Phospholipid, LPS, lipid A and drug exporter, MsbA, which flips the substrate from the inner leaflet of the cytoplasmic membrane to the outer leaflet (Eckford and Sharom, 2010). MsbA also confers drug resistance to azidopine, daunomycin, vinblastine, Hoechst 33342 and ethidium (Reuter et al., 2003). Four x-ray structures, trapped in different conformations, two with and two without nucleotide, have been solved (Ward et al., 2007). They suggest an alternating accessibility mode of transport with major conformational changes from Escherichia coli (see 11 papers)
msbA / MB|P60752 lipid A export ATP-binding/permease protein msbA; EC 3.6.3.- from Escherichia coli K12 (see 24 papers)
36% identity, 73% coverage of query (250 bits)
ABCB6_RAT / O70595 ATP-binding cassette sub-family B member 6; ABC-type heme transporter ABCB6; Ubiquitously-expressed mammalian ABC half transporter; EC 7.6.2.5 from Rattus norvegicus (Rat) (see 3 papers)
33% identity, 84% coverage of query (250 bits)
7ph2A Nanodisc reconstituted msba in complex with nanobodies, spin-labeled at position a60c
36% identity, 71% coverage of query (250 bits)
8dmmA Structure of the vanadate-trapped msba bound to kdl
36% identity, 71% coverage of query (250 bits)
7bcwA Structure of msba in salipro with adp vanadate
36% identity, 71% coverage of query (250 bits)
7ph3A / P60752 Amp-pnp bound nanodisc reconstituted msba with nanobodies, spin- labeled at position a60c (see paper)
36% identity, 71% coverage of query (249 bits)
ABCB7_ORYLA / H2LNR5 Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial from Oryzias latipes (Japanese rice fish) (Japanese killifish) (see paper)
32% identity, 82% coverage of query (249 bits)
MDR3_MOUSE / P21440 Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 2; Multidrug resistance protein 3; P-glycoprotein 2; P-glycoprotein 3; EC 7.6.2.1 from Mus musculus (Mouse) (see 14 papers)
33% identity, 82% coverage of query (249 bits)
ABCB7_DANRE / E7F6F7 Iron-sulfur clusters transporter ABCB7, mitochondrial; ATP-binding cassette sub-family B member 7, mitochondrial from Danio rerio (Zebrafish) (Brachydanio rerio) (see paper)
32% identity, 83% coverage of query (249 bits)
P63359 ABC-type lipid A-core oligosaccharide transporter (EC 7.5.2.6) from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
36% identity, 73% coverage of query (249 bits)
4m1mA / P21447 Corrected structure of mouse p-glycoprotein (see paper)
32% identity, 83% coverage of query (249 bits)
6bppA E. Coli msba in complex with lps and inhibitor g092
36% identity, 71% coverage of query (249 bits)
6bplA E. Coli msba in complex with lps and inhibitor g907
36% identity, 71% coverage of query (249 bits)
7mewA E. Coli msba in complex with g247
36% identity, 71% coverage of query (249 bits)
ATM1_CRYNH / J9VWU3 Iron-sulfur clusters transporter ATM1, mitochondrial; EC 7.-.-.- from Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) (see 3 papers)
30% identity, 97% coverage of query (248 bits)
7vgfA / O75027 Cryo-em structure of amp-pnp bound human abcb7
34% identity, 79% coverage of query (248 bits)
MDR3_RAT / Q08201 Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 2; Multidrug resistance protein 3; P-glycoprotein 2; P-glycoprotein 3; EC 7.6.2.1 from Rattus norvegicus (Rat) (see 3 papers)
Q08201 ABC-type xenobiotic transporter (EC 7.6.2.2) from Rattus norvegicus (see paper)
34% identity, 82% coverage of query (248 bits)
6fn1A Zosuquidar and uic2 fab complex of human-mouse chimeric abcb1 (abcb1hm)
32% identity, 81% coverage of query (248 bits)
6quzD / Q9WYC4 Structure of atpgs-bound outward-facing tm287/288 in complex with sybody sb_tm35 (see paper)
30% identity, 96% coverage of query (247 bits)
6qeeA Nanodisc reconstituted human-mouse chimeric abcb1 (abcb1hm)-eq mutant in complex with uic2 fab and zosuquidar.
32% identity, 81% coverage of query (247 bits)
4q9iA P-glycoprotein cocrystallised with qz-ala
32% identity, 82% coverage of query (246 bits)
7otgA Structure of abcb1/p-glycoprotein in the presence of the cftr potentiator ivacaftor
33% identity, 81% coverage of query (246 bits)
6q81A Structure of p-glycoprotein(abcb1) in the post-hydrolytic state
33% identity, 81% coverage of query (246 bits)
3g61A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
33% identity, 81% coverage of query (246 bits)
3g60A Structure of p-glycoprotein reveals a molecular basis for poly- specific drug binding
33% identity, 81% coverage of query (246 bits)
4xwkA P-glycoprotein co-crystallized with bde-100
33% identity, 81% coverage of query (246 bits)
7zk4A The abcb1 l335c mutant (mabcb1) in the outward facing state
33% identity, 82% coverage of query (246 bits)
7zkaA Abcb1 v978c mutant (mabcb1) in the outward facing state bound to aac
33% identity, 81% coverage of query (245 bits)
7zk6A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to 2 molecules of aac
33% identity, 81% coverage of query (245 bits)
7zk5A Abcb1 l335c mutant (mabcb1) in the outward facing state bound to aac
33% identity, 81% coverage of query (245 bits)
5koyA Mouse pgp 34 linker deleted bound with atp
32% identity, 81% coverage of query (244 bits)
ABCB9_HUMAN / Q9NP78 ABC-type oligopeptide transporter ABCB9; ATP-binding cassette sub-family B member 9; ATP-binding cassette transporter 9; ABC transporter 9 protein; hABCB9; TAP-like protein; TAPL; EC 7.4.2.6 from Homo sapiens (Human) (see 16 papers)
Q9NP78 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see 2 papers)
TC 3.A.1.209.2 / Q9NP78 Homodimeric transporter ABCB9 or TAPL. Transports a broad spectrum of peptides (low affinity) from the cytosol to the lysosomal lumen. It exists in two forms (812 aas and 1257 aas). The latter full length protein confers resistance to taxanes and anthracyclines (Kawanobe et al., 2012). Resistance and transport were demonstrated for paclitaxel and docetaxel. TapL transports a broad range of peptides of 6-60aas (23aas optimal). It has also been detected in the ER. It is stabilized by interaction with LAMP-1 and LAMP-2 (see 9.A.16) from Homo sapiens (see 18 papers)
31% identity, 92% coverage of query (244 bits)
MDR3_HUMAN / P21439 Phosphatidylcholine translocator ABCB4; ATP-binding cassette sub-family B member 4; Multidrug resistance protein 3; P-glycoprotein 3; EC 7.6.2.1 from Homo sapiens (Human) (see 28 papers)
TC 3.A.1.201.3 / P21439 Short chain fatty acid phosphatidylcholine translocase (phospholipid flippase), MDR3; AbcB4; Pgy3 from Homo sapiens (Human) (see 15 papers)
33% identity, 82% coverage of query (243 bits)
6qv0B Structure of atp-bound outward-facing tm287/288 in complex with sybody sb_tm35
30% identity, 96% coverage of query (243 bits)
7selA E. Coli msba in complex with lps and inhibitor g7090 (compound 3)
36% identity, 71% coverage of query (243 bits)
7niwA / P21439 Nanodisc reconstituted human abcb4 in complex with 4b1-fab (posaconazole-bound, inward-open conformation) (see paper)
32% identity, 91% coverage of query (242 bits)
6s7pA Nucleotide bound abcb4
33% identity, 81% coverage of query (241 bits)
ABCBA_MOUSE / Q9JI39 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein from Mus musculus (Mouse) (see 9 papers)
31% identity, 93% coverage of query (239 bits)
7v5cA / Q9JJ59 Cryo-em structure of the mouse abcb9 (adp.Bef3-bound) (see paper)
31% identity, 92% coverage of query (239 bits)
7vfiA Cryo-em structure of the mouse tapl (9mer-peptide bound)
31% identity, 92% coverage of query (238 bits)
ABCBA_HUMAN / Q9NRK6 ATP-binding cassette sub-family B member 10, mitochondrial; ABC-mitochondrial erythroid protein; ABC-me protein; ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2; M-ABC2 from Homo sapiens (Human) (see 7 papers)
Q9NRK6 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
30% identity, 96% coverage of query (236 bits)
5ochE / Q9NUT2 The crystal structure of human abcb8 in an outward-facing state
32% identity, 90% coverage of query (232 bits)
MITOS_HUMAN / Q9NUT2 Mitochondrial potassium channel ATP-binding subunit; ATP-binding cassette sub-family B member 8, mitochondrial; ABCB8; Mitochondrial ATP-binding cassette 1; M-ABC1; Mitochondrial sulfonylurea-receptor; MITOSUR from Homo sapiens (Human) (see 5 papers)
Q9NUT2 bacterial ABC-type protein transporter (EC 7.4.2.5) from Homo sapiens (see paper)
TC 3.A.1.201.22 / Q9NUT2 Mitochondrial ATP-binding cassette 1, ABCB8 from Homo sapiens
32% identity, 92% coverage of query (229 bits)
4ayxA / Q9NRK6 Structure of the human mitochondrial abc transporter, abcb10 (rod form b) (see paper)
30% identity, 94% coverage of query (226 bits)
Build an alignment for Ga0059261_2137 and 91 homologs with ≥ 30% identity
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7pr1A / G0SBE6 Structure of ctatm1 in the occluded conformation with atp bound (see paper)
29% identity, 90% coverage of query (225 bits)
7zoaB / Q2YQ73 Cryo-em structure of cgt abc transporter in presence of cbg substrate (see paper)
32% identity, 93% coverage of query (225 bits)
7pruA Structure of ctatm1 in the inward-facing partially occluded with cargo bound
29% identity, 90% coverage of query (225 bits)
7znuA Cryo-em structure of cgt abc transporter in detergent micelle
32% identity, 91% coverage of query (224 bits)
7ehlA Cryo-em structure of human abcb8 transporter in nucleotide binding state
33% identity, 90% coverage of query (221 bits)
ABCBB_HUMAN / O95342 Bile salt export pump; ATP-binding cassette sub-family B member 11; EC 7.6.2.- from Homo sapiens (Human) (see 21 papers)
TC 3.A.1.201.2 / O95342 Bile salt export pump, BSEP, ABCB11 or SPGP in the canalicular membrane of liver cells, is associated with progressive familial intrahepatic cholestasis-2 and benign recurrent intrahepatic cholestasis (Kagawa et al., 2008; Stindt et al. 2013; Park et al. 2016). It exports unconjugaged bile salts and glycine conjugates > taurine conjugates as well as the statin, pravastatin (Nigam 2015). BSEP mediates biliary excretion of bile acids from hepatocytes. Compounds based on GW4064 (Q96RI1), a representative farnesoid X receptor (RXR) agonist, enhance E297G BSEP transport activity from Homo sapiens (Human) (see 11 papers)
32% identity, 88% coverage of query (218 bits)
7dv5U / O95342 Human bile salt exporter abcb11 in complex with taurocholate (see paper)
32% identity, 86% coverage of query (216 bits)
7y48B Cryo-em structure of biliverdin-bound mitochondrial abc transporter abcb10 from biortus
29% identity, 94% coverage of query (214 bits)
6a6mA / M1VAN7 Crystal structure of an outward-open nucleotide-bound state of the eukaryotic abc multidrug transporter cmabcb1 (see paper)
34% identity, 74% coverage of query (213 bits)
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Lawrence Berkeley National Laboratory