Searching for up to 100 curated homologs for Ga0059261_2977 FitnessBrowser__Korea:Ga0059261_2977 (432 a.a.)
Found high-coverage hits (≥70%) to 44 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Pf1N1B4_5129 D-galacturonate transporter ExuT from Pseudomonas fluorescens FW300-N1B4
40% identity, 97% coverage of query (301 bits)
CA265_RS19855 D-galacturonate transporter ExuT from Pedobacter sp. GW460-11-11-14-LB5
33% identity, 96% coverage of query (257 bits)
BT4105 D-galacturonate transporter ExuT from Bacteroides thetaiotaomicron VPI-5482
35% identity, 81% coverage of query (236 bits)
HSERO_RS23010 D-galacturonate transporter ExuT from Herbaspirillum seropedicae SmR1
31% identity, 88% coverage of query (210 bits)
ExuT / b3093 hexuronate transporter from Escherichia coli K-12 substr. MG1655 (see 5 papers)
exuT / P0AA78 hexuronate transporter from Escherichia coli (strain K12) (see 3 papers)
EXUT_ECOLI / P0AA78 Hexuronate transporter; Aldohexuronate transport system from Escherichia coli (strain K12) (see 5 papers)
32% identity, 89% coverage of query (200 bits)
TC 2.A.1.14.2 / P0AA78 Hexuronate (glucuronate; galacturonate) porter, ExuT (Nemoz et al. 1976). It also transports D-glucose (HJ Kim et al., Front. Microbiol., 23 January 2020) from Escherichia coli (see 3 papers)
32% identity, 89% coverage of query (200 bits)
EXUT_DICCH / P94774 Galacturonate transporter from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see 3 papers)
TC 2.A.1.14.41 / P94774 The Aldohexuronate (glucuronate, galacturonate) uptake porter from Dickeya chrysanthemi
exuT / AAB70881.1 exuT from Dickeya chrysanthemi (see paper)
33% identity, 75% coverage of query (178 bits)
LgoT / b4356 galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lgoT / P39398 galactonate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
LGOT_ECOLI / P39398 Probable L-galactonate transporter; Galactonate:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
yjjL / RF|NP_418776 inner membrane transport protein yjjL from Escherichia coli K12 (see 2 papers)
32% identity, 75% coverage of query (173 bits)
Build an alignment for Ga0059261_2977 and 8 homologs with ≥ 30% identity
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YidT / b3691 D-galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 9 papers)
dgoT / P0AA76 D-galactonate:H+ symporter from Escherichia coli (strain K12) (see 11 papers)
DGOT_ECOLI / P0AA76 D-galactonate transporter; D-galactonate/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.14.7 / P0AA76 Galactonate transporter from Escherichia coli (see 4 papers)
28% identity, 94% coverage of query (162 bits)
6e9nA / J7QAK3 E. Coli d-galactonate:proton symporter in the inward open form (see paper)
28% identity, 93% coverage of query (160 bits)
PS417_04205 D-galacturonate transporter (MFS superfamily) from Pseudomonas simiae WCS417
29% identity, 91% coverage of query (152 bits)
GarP / b3127 galactarate/D-glucarate transporter GarP from Escherichia coli K-12 substr. MG1655 (see 6 papers)
garP / P0AA80 galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 5 papers)
GARP_ECOLI / P0AA80 Probable galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 2 papers)
28% identity, 87% coverage of query (152 bits)
TC 2.A.1.14.14 / Q8FDB7 Probable D-galactarate (glucarate?):H+ symporter, GarP or YhaU from Escherichia coli O6 (see paper)
28% identity, 87% coverage of query (152 bits)
GUDP_BACSU / P42237 Probable galactarate/D-glucarate transporter GudP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.14.1 / P42237 Glucarate porter from Bacillus subtilis (see 3 papers)
27% identity, 96% coverage of query (152 bits)
SAUU_CUPNH / Q0K843 Probable sulfoacetate transporter SauU from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
29% identity, 96% coverage of query (146 bits)
6e9oA E. Coli d-galactonate:proton symporter mutant e133q in the outward substrate-bound form
27% identity, 93% coverage of query (140 bits)
ANTR2_ARATH / Q8GX78 Ascorbate transporter, chloroplastic; Phosphate transporter PHT4;4; AtPHT4;4; Probable anion transporter 2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
28% identity, 93% coverage of query (125 bits)
GudP / b2789 galactarate/D-glucarate transporter GudP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gudP / Q46916 galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 5 papers)
GUDP_ECOLI / Q46916 Probable galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.14.40 / C4ZZU4 Glucarate transporter, GudP. Encoded in an operon with GudD, a glucarate dehydratase from Escherichia coli (strain K12 / MC4100 / BW2952)
25% identity, 95% coverage of query (124 bits)
AO356_28540 D-mannose transporter from Pseudomonas fluorescens FW300-N2C3
26% identity, 96% coverage of query (112 bits)
ANTR1_ARATH / O82390 Sodium-dependent phosphate transport protein 1, chloroplastic; Anion transporter 1; Na(+)/PI cotransporter 1; Phosphate transporter PHT4;1; Sodium/phosphate cotransporter 1 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
O82390 ABC-type phosphate transporter (EC 7.3.2.1) from Arabidopsis thaliana (see 2 papers)
TC 2.A.1.14.22 / O82390 The chloroplast thylakoid Na+:phosphate symporter, ANTR1 (512aas) (Pavón et al., 2008). Residues essential for function have been identified from Arabidopsis thaliana (see 7 papers)
25% identity, 93% coverage of query (110 bits)
ANTR4_ARATH / Q66GI9 Probable anion transporter 4, chloroplastic; Phosphate transporter PHT4;3 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
26% identity, 91% coverage of query (95.5 bits)
ANTR3_ARATH / Q7XJR2 Probable anion transporter 3, chloroplastic; Phosphate transporter PHT4;2 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q7XJR2 ABC-type phosphate transporter (EC 7.3.2.1) from Arabidopsis thaliana (see paper)
23% identity, 95% coverage of query (85.9 bits)
S17A9_HUMAN / Q9BYT1 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Homo sapiens (Human) (see 4 papers)
TC 2.A.1.14.21 / Q9BYT1 The vesicular purine nucleotide (ADP, ATP, GTP) transporter, VNUT or SLC17A9. It is found in synaptic vesicles and chromafin granules (Sawada et al., 2008)) and is associated with disseminated superficial actinic porokeratosis (DSAP), a rare autosomal dominant genodermatosis (Cui et al. 2014). It plays a key role in purinergic signaling through its ability to transport nucleotides using the pmf. It catalyzes Cl--dependent transport activity involving essential arginines in the transmembrane region. Ketoacids inhibit these transporters through modulation of Cl- activation, but Cl- and the arginine residues are not important for ATP binding (Iwai et al. 2019). High expression of SLC17A9 correlates with a poor prognosis for colorectal cancer from Homo sapiens (Human) (see 5 papers)
22% identity, 85% coverage of query (81.6 bits)
BWI76_RS23725 2-deoxy-D-ribonate transporter 2 from Klebsiella michiganensis M5al
24% identity, 95% coverage of query (81.3 bits)
S17A9_MOUSE / Q8VCL5 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Mus musculus (Mouse) (see 5 papers)
21% identity, 92% coverage of query (73.6 bits)
ANTR5_ARATH / Q9FKV1 Probable anion transporter 5; Phosphate transporter PHT4;6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
23% identity, 86% coverage of query (72.8 bits)
S17A9_RAT / P0DX21 Voltage-gated purine nucleotide uniporter SLC17A9; Solute carrier family 17 member 9; Vesicular nucleotide transporter; VNUT from Rattus norvegicus (Rat) (see 2 papers)
22% identity, 92% coverage of query (72.8 bits)
TC 2.A.1.8.11 / Q93PW1 NarK, component of The 24 TMS, 2 domain, NarK1-NarK2 porter (NarK1 = a NO3-/H+ symporter; NarK2 = a NO3-/NO2- antiporter) from Paracoccus pantotrophus (Thiosphaera pantotropha) (see paper)
23% identity, 82% coverage of query (70.5 bits)
TC 2.A.1.14.26 / F2YPN7 The plasma membrane Lethal (2)01810 glutamate uptake porter (Km=0.07μM) (Inhibited by aspartate) from Drosophila melanogaster
23% identity, 93% coverage of query (68.6 bits)
Q9HTV5 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Pseudomonas aeruginosa (see paper)
24% identity, 88% coverage of query (68.6 bits)
YfaV / b2246 putative transporter YfaV from Escherichia coli K-12 substr. MG1655 (see 4 papers)
TC 2.A.1.14.35 / P76470 Inner membrane transport protein RhmT from Escherichia coli (strain K12) (see 4 papers)
24% identity, 84% coverage of query (65.9 bits)
ANTR6_ARATH / Q3E9A0 Probable anion transporter 6, chloroplastic; Phosphate transporter PHT4;5 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
23% identity, 86% coverage of query (65.9 bits)
G6PT3_MOUSE / Q9WU81 Glucose-6-phosphate exchanger SLC37A2; Solute carrier family 37 member 2; cAMP-inducible protein 2 from Mus musculus (Mouse) (see paper)
23% identity, 86% coverage of query (65.5 bits)
PS417_07260 2-deoxy-D-ribonate transporter 2 from Pseudomonas simiae WCS417
22% identity, 98% coverage of query (65.1 bits)
G6PT1_HUMAN / O43826 Glucose-6-phosphate exchanger SLC37A4; Glucose-5-phosphate transporter; Glucose-6-phosphate translocase; Solute carrier family 37 member 4; Transformation-related gene 19 protein; TRG-19 from Homo sapiens (Human) (see 24 papers)
TC 2.A.1.4.5 / O43826 Microsomal (ER/Golgi) glucose-6-P:Pi antiporter (glycogen storage disease (GSD1b and 1c); Gierke''s disease protein) (SLC37A2 in mice, associated with white adipose tissue obesity and expressed at high levels in macrophage) (4 isoforms present in humans (Chen et al., 2008)) from Homo sapiens (Human) (see 23 papers)
SLC37A4 / RF|NP_001458.1 glucose-6-phosphate translocase from Homo sapiens
21% identity, 86% coverage of query (65.1 bits)
TC 2.A.1.15.7 / Q6FBB3 Aromatic compound (benzoate) uptake transporter of 450 aas from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
23% identity, 87% coverage of query (63.9 bits)
GlpT / b2240 sn-glycerol 3-phosphate:phosphate antiporter from Escherichia coli K-12 substr. MG1655 (see 24 papers)
glpT / P08194 sn-glycerol 3-phosphate:phosphate antiporter from Escherichia coli (strain K12) (see 48 papers)
TC 2.A.1.4.3 / P08194 Glycerol-P:Pi antiporter (may function by a 'rocker switch' mechanism; Law et al., 2007). The 3-d structure is known (3.3Å resolution) (Huang et al., 2003; Lemieux et al., 2005; Lemieux, 2007) from Escherichia coli (see 7 papers)
23% identity, 84% coverage of query (63.5 bits)
NIAP_ACIAD / Q6FFF7 Niacin transporter NiaP from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
22% identity, 72% coverage of query (61.6 bits)
BWI76_RS23715 2-deoxy-D-ribonate transporter 1 from Klebsiella michiganensis M5al
25% identity, 93% coverage of query (61.2 bits)
Q03567 Uncharacterized transporter slc-17.2 from Caenorhabditis elegans
24% identity, 78% coverage of query (60.8 bits)
G6PT3_HUMAN / Q8TED4 Glucose-6-phosphate exchanger SLC37A2; Solute carrier family 37 member 2 from Homo sapiens (Human) (see paper)
TC 2.A.1.4.8 / Q8TED4 solute carrier family 37 (putative glycerol-3-phosphate transporter), member 2. Has been shown to catalyze glucose 6-P:Pi antiport across the endoplasmic reticular membrane from Homo sapiens (see 3 papers)
22% identity, 86% coverage of query (59.7 bits)
TC 2.A.1.4.11 / Q9ZE92 Glycerol-3-phosphate:inorganic phosphate antiporter, GlpT from Rickettsia prowazekii (strain Madrid E)
22% identity, 84% coverage of query (59.3 bits)
TC 2.A.1.14.8 / Q9RPP3 Phthalate porter from Burkholderia cepacia (Pseudomonas cepacia) (see paper)
22% identity, 95% coverage of query (59.3 bits)
MHBT_KLEOX / Q5EXK5 3-hydroxybenzoate transporter MhbT from Klebsiella oxytoca (see paper)
23% identity, 95% coverage of query (55.5 bits)
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Lawrence Berkeley National Laboratory